Marilyn Huckans

Associate Professor

  • 1056 Citations
  • 18 h-Index
20042019
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Research Output 2005 2019

  • 1056 Citations
  • 18 h-Index
  • 36 Article
  • 1 Review article
2019

Neuroinflammation in addiction: A review of neuroimaging studies and potential immunotherapies

Kohno, M., Link, J., Dennis, L. E., McCready, H., Huckans, M., Hoffman, W. F. & Loftis, J., Apr 1 2019, In : Pharmacology Biochemistry and Behavior. 179, p. 34-42 9 p.

Research output: Contribution to journalReview article

Neuroimaging
pioglitazone
Immunotherapy
Minocycline
Methamphetamine
2018

Functional MRI and delay discounting in patients infected with hepatitis C

McCready, H., Kohno, M., Kolessar, M., Dennis, L., Kriz, D., Luber, H., Anderson, R., Chang, M., Sasaki, A., Flora, K., Vandenbark, A., Mitchell, S., Loftis, J., Hoffman, W. F. & Huckans, M., Jan 1 2018, (Accepted/In press) In : Journal of NeuroVirology.

Research output: Contribution to journalArticle

Impulsive Behavior
Hepatitis C
Parietal Lobe
Viral Load
Reward

Parallel Effects of Methamphetamine on Anxiety and CCL3 in Humans and a Genetic Mouse Model of High Methamphetamine Intake

Huckans, M., Wilhelm, C., Phillips, T., Huang, E. T., Hudson, R. & Loftis, J., Jan 18 2018, (Accepted/In press) In : Neuropsychobiology.

Research output: Contribution to journalArticle

Methamphetamine
Genetic Models
Medical Genetics
Anxiety
Drinking
4 Citations (Scopus)

The relationship between interleukin-6 and functional connectivity in methamphetamine users

Kohno, M., Loftis, J., Huckans, M., Dennis, L. E., McCready, H. & Hoffman, W. F., Jun 11 2018, In : Neuroscience Letters. 677, p. 49-54 6 p.

Research output: Contribution to journalArticle

Methamphetamine
Interleukin-6
Inflammation
Corpus Striatum
Microglia
2017
1 Citation (Scopus)

Mental Health Does Not Moderate Compensatory Cognitive Training Efficacy for Veterans With a History of Mild Traumatic Brain Injury

Pagulayan, K. F., O'Neil, M., Williams, R. M., Turner, A. P., Golshan, S., Roost, M. S., Laman-Maharg, B., Huckans, M., Storzbach, D. & Twamley, E. W., 2017, (Accepted/In press) In : Archives of Physical Medicine and Rehabilitation.

Research output: Contribution to journalArticle

Brain Concussion
Veterans
2003-2011 Iraq War
Mental Health
Afghan Campaign 2001-
5 Citations (Scopus)
Immunologic Factors
Alcoholism
Alcohols
Data storage equipment
Tissue Inhibitor of Metalloproteinase-1
2016
14 Citations (Scopus)

Compensatory Cognitive Training for Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn Veterans With Mild Traumatic Brain Injury

Storzbach, D., Twamley, E. W., Roost, M. S., Golshan, S., Williams, R. M., O'Neil, M., Jak, A. J., Turner, A. P., Kowalski, H. M., Pagulayan, K. F. & Huckans, M., Mar 28 2016, (Accepted/In press) In : Journal of Head Trauma Rehabilitation.

Research output: Contribution to journalArticle

2003-2011 Iraq War
Afghan Campaign 2001-
Brain Concussion
Veterans
Learning
6 Citations (Scopus)

Everyday problems with executive dysfunction and impulsivity in adults recovering from methamphetamine addiction

Ellis, C., Hoffman, W., Jaehnert, S., Plagge, J., Loftis, J., Schwartz, D. & Huckans, M., 2016, In : Addictive Disorders and their Treatment. 15, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Methamphetamine
Impulsive Behavior
Self Report
Research Design
7 Citations (Scopus)

Sensory sensitivity in operation enduring freedom/operation Iraqi freedom veterans with and without blast exposure and mild traumatic brain injury

Callahan, M. L., Binder, L. M., O'Neil, M., Zaccari, B., Roost, M. S., Golshan, S., Huckans, M., Fann, J. R. & Storzbach, D., Dec 9 2016, (Accepted/In press) In : Applied Neuropsychology. p. 1-11 11 p.

Research output: Contribution to journalArticle

2003-2011 Iraq War
Afghan Campaign 2001-
Brain Concussion
Veterans
Photophobia
2015
24 Citations (Scopus)

A longitudinal study evaluating the effects of interferon-alpha therapy on cognitive and psychiatric function in adults with chronic hepatitis C

Huckans, M., Fuller, B., Wheaton, V., Jaehnert, S., Ellis, C., Kolessar, M., Kriz, D., Anderson, J. R., Berggren, K., Olavarria, H., Sasaki, A. W., Chang, M., Flora, K. D. & Loftis, J., Feb 1 2015, In : Journal of Psychosomatic Research. 78, 2, p. 184-192 9 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Virus Diseases
Interferon-alpha
Hepacivirus
Cognition
27 Citations (Scopus)
2003-2011 Iraq War
Afghan Campaign 2001-
Brain Concussion
Neuropsychological Tests
Veterans
17 Citations (Scopus)
Protein Array Analysis
Methamphetamine
Immunologic Factors
Anxiety
Depression
2014
23 Citations (Scopus)

Multi-analyte profile analysis of plasma immune proteins: Altered expression of peripheral immune factors is associated with neuropsychiatric symptom severity in adults with and without chronic hepatitis C virus infection

Huckans, M., Fuller, B. E., Olavarria, H., Sasaki, A. W., Chang, M., Flora, K. D., Kolessar, M., Kriz, D., Anderson, J. R., Vandenbark, A. & Loftis, J., 2014, In : Brain and Behavior. 4, 2, p. 123-142 20 p.

Research output: Contribution to journalArticle

Immunologic Factors
Chronic Hepatitis C
Virus Diseases
Hepacivirus
Blood Proteins
2013
18 Citations (Scopus)
Adipokines
Rats
Sprague Dawley Rats
Depression
Genes
8 Citations (Scopus)
Bipolar Disorder
Schizophrenia
Placebos
Psychiatry
Tea
71 Citations (Scopus)

Efficacy of cognitive rehabilitation therapies for mild cognitive impairment (MCI) in older adults: Working toward a theoretical model and evidence-based interventions

Huckans, M., Hutson, L., Twamley, E., Jak, A., Kaye, J. & Storzbach, D., Mar 2013, In : Neuropsychology Review. 23, 1, p. 63-80 18 p.

Research output: Contribution to journalArticle

Cognitive Therapy
Theoretical Models
Rehabilitation
Dementia
Cognitive Dysfunction
9 Citations (Scopus)
Methamphetamine
immunotherapy
relapse
cytokines
peptides
9 Citations (Scopus)

Protective effects of higher cognitive reserve for neuropsychological and daily functioning among individuals infected with hepatitis C

Sakamoto, M., Woods, S. P., Kolessar, M., Kriz, D., Anderson, J. R., Olavarria, H., Sasaki, A. W., Chang, M., Flora, K. D., Loftis, J. & Huckans, M., Oct 2013, In : Journal of NeuroVirology. 19, 5, p. 442-451 10 p.

Research output: Contribution to journalArticle

Cognitive Reserve
Hepatitis C
Hepacivirus
Executive Function
Wounds and Injuries
15 Citations (Scopus)

Substance use disorders: Psychoneuroimmunological mechanisms and new targets for therapy

Loftis, J. & Huckans, M., Aug 2013, In : Pharmacology and Therapeutics. 139, 2, p. 289-300 12 p.

Research output: Contribution to journalArticle

Substance-Related Disorders
Central Nervous System
Psychoneuroimmunology
Medicine
Therapeutics
34 Citations (Scopus)

Vulnerability to somatic symptoms of depression during interferon-alpha therapy for hepatitis C: A 16-week prospective study

Loftis, J., Patterson, A. L., Wilhelm, C., McNett, H., Morasco, B., Huckans, M., Morgan, T., Saperstein, S., Asghar, A. & Hauser, P., Jan 2013, In : Journal of Psychosomatic Research. 74, 1, p. 57-63 7 p.

Research output: Contribution to journalArticle

Hepatitis C
Interferon-alpha
Prospective Studies
Depression
Veterans
2012
8 Citations (Scopus)

Corticotropin releasing factor-1 receptor antagonism alters the biochemical, but not behavioral effects of repeated interleukin-1β administration

Wilhelm, C., Murphy-Crews, A., Menasco, D. J., Huckans, M. & Loftis, J., Jan 2012, In : Neuropharmacology. 62, 1, p. 313-321 9 p.

Research output: Contribution to journalArticle

Interleukin-1
p38 Mitogen-Activated Protein Kinases
Cytokines
Corticotropin-Releasing Hormone
Illness Behavior
2011
3 Citations (Scopus)

Cognitive enhancement in combination with 'brain repair' may be optimal for the treatment of stimulant addiction

Loftis, J. & Huckans, M., May 2011, In : Addiction. 106, 5, p. 1021-1022 2 p.

Research output: Contribution to journalArticle

Cognition Disorders
Amphetamine-Related Disorders
Nootropic Agents
Combined Modality Therapy
Methamphetamine
26 Citations (Scopus)

Discounting of delayed rewards and executive dysfunction in individuals infected with hepatitis C

Huckans, M., Seelye, A., Woodhouse, J., Parcel, T., Mull, L., Schwartz, D., Mitchell, A., Lahna, D., Johnson, A., Loftis, J., Woods, S. P., Mitchell, S. & Hoffman, W., Feb 2011, In : Journal of Clinical and Experimental Neuropsychology. 33, 2, p. 176-186 11 p.

Research output: Contribution to journalArticle

Hepatitis C
Reward
Substance-Related Disorders
Decision Making
Interviews
64 Citations (Scopus)

Methamphetamine causes persistent immune dysregulation: A cross-species, translational report

Loftis, J., Choi, D., Hoffman, W. & Huckans, M., Jul 2011, In : Neurotoxicity Research. 20, 1, p. 59-68 10 p.

Research output: Contribution to journalArticle

Methamphetamine
Chemokines
Intercellular Adhesion Molecule-1
Cytokines
Brain
2010
21 Citations (Scopus)

Antiviral therapy completion and response rates among hepatitis c patients with and without schizophrenia

Huckans, M., Mitchell, A., Ruimy, S., Loftis, J. & Hauser, P., Jan 2010, In : Schizophrenia Bulletin. 36, 1, p. 165-172 8 p.

Research output: Contribution to journalArticle

Hepatitis
Antiviral Agents
Schizophrenia
Genotype
Therapeutics
30 Citations (Scopus)
Veterans
Psychiatry
Afghanistan
Iraq
Neurobehavioral Manifestations
94 Citations (Scopus)

Global and local morphometric differences in recently abstinent methamphetamine-dependent individuals

Schwartz, D. L., Mitchell, A. D., Lahna, D. L., Luber, H. S., Huckans, M., Mitchell, S. & Hoffman, W. F., May 1 2010, In : NeuroImage. 50, 4, p. 1392-1401 10 p.

Research output: Contribution to journalArticle

Methamphetamine
Impulsive Behavior
Addictive Behavior
Specific Gravity
Gyrus Cinguli
137 Citations (Scopus)
Neuroimmunomodulation
Depression
Cytokines
Therapeutics
Diagnostic and Statistical Manual of Mental Disorders
21 Citations (Scopus)

Predictors of pain intensity and pain functioning in patients with the hepatitis C virus

Morasco, B., Huckans, M., Loftis, J., Woodhouse, J., Seelye, A., Turk, D. C. & Hauser, P., 2010, In : General Hospital Psychiatry. 32, 4, p. 413-418 6 p.

Research output: Contribution to journalArticle

Hepacivirus
Pain
Psychology
Pain Measurement
Medical Records
16 Citations (Scopus)

The influence of antiviral therapy on psychiatric symptoms among patients with hepatitis C and schizophrenia

Huckans, M., Mitchell, A., Pavawalla, S., Morasco, B., Ruimy, S., Loftis, J., Rifai, M. A. & Hauser, P., 2010, In : Antiviral Therapy. 15, 1, p. 111-119 9 p.

Research output: Contribution to journalArticle

Hepatitis C
Antiviral Agents
Psychiatry
Schizophrenia
Therapeutics
2009
32 Citations (Scopus)

The cognitive effects of hepatitis C in the presence and absence of a history of substance use disorder

Huckans, M., Seelye, A., Parcel, T., Mull, L., Woodhouse, J., Bjornson, D., Fuller, B. E., Loftis, J., Morasco, B., Sasaki, A. W., Storzbach, D. & Hauser, P., 2009, In : Journal of the International Neuropsychological Society. 15, 1, p. 69-82 14 p.

Research output: Contribution to journalArticle

Hepatitis C
Substance-Related Disorders
Hepacivirus
Verbal Learning
Veterans
2008
137 Citations (Scopus)

Cortical activation during delay discounting in abstinent methamphetamine dependent individuals

Hoffman, W. F., Schwartz, D. L., Huckans, M., McFarland, B., Meiri, G., Stevens, A. & Mitchell, S., Dec 2008, In : Psychopharmacology. 201, 2, p. 183-193 11 p.

Research output: Contribution to journalArticle

Methamphetamine
Reward
Parietal Lobe
Prefrontal Cortex
Gyrus Cinguli
87 Citations (Scopus)

Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1β and tumor necrosis factor-α

Loftis, J., Huckans, M., Ruimy, S., Hinrichs, D. J. & Hauser, P., Jan 17 2008, In : Neuroscience Letters. 430, 3, p. 264-268 5 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Interleukin-1
Tumor Necrosis Factor-alpha
Depression
Cytokines
25 Citations (Scopus)

Hepatitis C testing and infection rates in bipolar patients with and without comorbid substance use disorders

Matthews, A., Huckans, M., Blackwell, A. D. & Hauser, P., Mar 2008, In : Bipolar Disorders. 10, 2, p. 266-270 5 p.

Research output: Contribution to journalArticle

Hepatitis C
Substance-Related Disorders
Infection
Control Groups
Bipolar Disorder
2007
13 Citations (Scopus)
Hepatitis C
Interferon-alpha
Substance-Related Disorders
Virus Diseases
Genotype
2006
26 Citations (Scopus)

Management of hepatitis C disease among VA patients with schizophrenia and substance use disorders

Huckans, M., Blackwell, A. D., Harms, T. A. & Hauser, P., Mar 2006, In : Psychiatric Services. 57, 3, p. 403-406 4 p.

Research output: Contribution to journalArticle

Hepatitis C
schizophrenia
Substance-Related Disorders
contagious disease
Schizophrenia
2005
24 Citations (Scopus)

Integrated hepatitis C virus treatment: Addressing comorbid substance use disorders and HIV infection

Huckans, M., Blackwell, A. D., Harms, T. A., Indest, D. W. & Hauser, P., Oct 2005, In : AIDS. 19, SUPPL. 3

Research output: Contribution to journalArticle

Hepacivirus
HIV Infections
Substance-Related Disorders
HIV
Veterans