Maria Fleseriu

Professor

  • 2220 Citations
  • 24 h-Index
20062019
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Research Output 2006 2019

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Article
2019
Somatostatin Receptors
Gallium
Cushing Syndrome
Adrenocorticotropic Hormone
Neoplasms

Ipilimumab-induced hypophysitis, a single academic center experience

Snyders, T., Chakos, D., Swami, U., Latour, E., Chen, Y., Fleseriu, M., Milhem, M., Zakharia, Y. & Zahr, R., Jan 1 2019, In : Pituitary.

Research output: Contribution to journalArticle

Melanoma
Survival
Hypophysitis
ipilimumab
Disease-Free Survival
2 Citations (Scopus)

Psychological effects of dopamine agonist treatment in patients with hyperprolactinemia and prolactin-secreting adenomas

Ioachimescu, A. G., Fleseriu, M., Hoffman, A. R., Vaughan, T. B. & Katznelson, L., Jan 1 2019, In : European Journal of Endocrinology. 180, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

Hyperprolactinemia
Dopamine Agonists
Prolactin
Adenoma
Psychology

Safety and efficacy of subcutaneous pasireotide in patients with Cushing’s disease: Results from an open-label, multicenter, single-arm, multinational, expanded-access study

Fleseriu, M., Iweha, C., Salgado, L., Mazzuco, T. L., Campigotto, F., Maamari, R. & Limumpornpetch, P., Jan 1 2019, In : Frontiers in Endocrinology. 10, JULY, 436.

Research output: Contribution to journalArticle

Open Access
Pituitary ACTH Hypersecretion
Safety
Hyperglycemia
Hydrocortisone
Quality of Life
7 Citations (Scopus)

Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update

Gadelha, M. R., Kasuki, L., Lim, D. S. T. & Fleseriu, M., Feb 1 2019, In : Endocrine Reviews. 40, 1, p. 268-332 65 p.

Research output: Contribution to journalArticle

Acromegaly
Mortality
Therapeutics
Diabetes Complications
Insulin-Like Growth Factor I
2018
4 Citations (Scopus)
Prolactinoma
ACTH-Secreting Pituitary Adenoma
Residual Neoplasm
Pituitary Neoplasms
Optic Chiasm
22 Citations (Scopus)

Efficacy and safety of once-monthly pasireotide in Cushing's disease: a 12 month clinical trial

for the & Pasireotide G2304 Study Group, Jan 1 2018, In : The Lancet Diabetes and Endocrinology. 6, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

Pituitary ACTH Hypersecretion
Clinical Trials
Safety
Hydrocortisone
pasireotide
1 Citation (Scopus)
Central Nervous System Cysts
Adrenal Insufficiency
Headache
Recurrence
Cysts

Non-functioning pituitary adenomas, not all the same and certainly not boring!

Fleseriu, M. & Karavitaki, N., Feb 13 2018, (Accepted/In press) In : Pituitary. p. 1-2 2 p.

Research output: Contribution to journalArticle

Pituitary Neoplasms
3 Citations (Scopus)

Physicians’ awareness of gadolinium retention and MRI timing practices in the longitudinal management of pituitary tumors: a “Pituitary Society” survey

Nachtigall, L. B., Karavitaki, N., Kiseljak-Vassiliades, K., Ghalib, L., Fukuoka, H., Syro, L. V., Kelly, D. & Fleseriu, M., Jan 1 2018, (Accepted/In press) In : Pituitary.

Research output: Contribution to journalArticle

Gadolinium
Pituitary Neoplasms
Contrast Media
Magnetic Resonance Imaging
Physicians

Recombinant growth hormone treatment, osteoporosis and fractures, more complicated than it seems!

Fleseriu, M., Jan 19 2018, (Accepted/In press) In : Endocrine. p. 1-3 3 p.

Research output: Contribution to journalArticle

Growth Hormone
Osteoporosis
6 Citations (Scopus)

Silent somatotroph pituitary adenomas: an update

Langlois, F., Woltjer, R. R., Cetas, J. & Fleseriu, M., Jan 5 2018, (Accepted/In press) In : Pituitary. p. 1-9 9 p.

Research output: Contribution to journalArticle

Growth Hormone-Secreting Pituitary Adenoma
Pituitary Neoplasms
Acromegaly
Neoplasms
Neuroendocrine Tumors
2017
2 Citations (Scopus)

Candida Meningitis After Transsphenoidal Surgery: A Single-Institution Case Series and Literature Review

Bridges, K. J., Li, R., Fleseriu, M. & Cetas, J., Dec 1 2017, In : World Neurosurgery. 108, p. 41-49 9 p.

Research output: Contribution to journalArticle

Candida
Meningitis
Neurosurgical Procedures
Flucytosine
Indwelling Catheters
8 Citations (Scopus)

Clinical profile of silent growth hormone pituitary adenomas; higher recurrence rate compared to silent gonadotroph pituitary tumors, a large single center experience

Langlois, F., Lim, D. S. T., Varlamov, E., Yedinak, C. C., Cetas, J., McCartney, S., Dogan, A. & Fleseriu, M., Oct 17 2017, (Accepted/In press) In : Endocrine. p. 1-7 7 p.

Research output: Contribution to journalArticle

Gonadotrophs
Pituitary Neoplasms
Adenoma
Growth Hormone
Recurrence
33 Citations (Scopus)

Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): A Pituitary Society Statement

On behalf of The Pituitary Society, Expert Group on Pituitary Tumors, Oct 1 2017, In : Pituitary. 20, 5, p. 489-498 10 p.

Research output: Contribution to journalArticle

Pituitary Neoplasms
Pituitary Diseases
Advisory Committees
Patient Care
Organizations
1 Citation (Scopus)
Pituitary ACTH Hypersecretion
Therapeutics
pasireotide
Glycosylated Hemoglobin A
Gallstones
11 Citations (Scopus)

Predictors of silent corticotroph adenoma recurrence; a large retrospective single center study and systematic literature review

Langlois, F., Lim, D. S. T., Yedinak, C. C., Cetas, I., McCartney, S., Cetas, J., Dogan, A. & Fleseriu, M., Oct 14 2017, (Accepted/In press) In : Pituitary. p. 1-9 9 p.

Research output: Contribution to journalArticle

ACTH-Secreting Pituitary Adenoma
Recurrence
Gonadotrophs
Adenoma
Adrenocorticotropic Hormone
10 Citations (Scopus)

Update on adrenal insufficiency: diagnosis and management in pregnancy

Langlois, F., Lim, D. S. T. & Fleseriu, M., Mar 10 2017, (Accepted/In press) In : Current Opinion in Endocrinology, Diabetes and Obesity.

Research output: Contribution to journalArticle

Adrenal Insufficiency
Hydrocortisone
Pregnancy
11-beta-Hydroxysteroid Dehydrogenases
Glucocorticoids

Vitamin D Hormone: Where Do We Stand, Where Are We Heading?

Ben-Shlomo, A. & Fleseriu, M., 2017, (Accepted/In press) In : Endocrinology and Metabolism Clinics of North America.

Research output: Contribution to journalArticle

Vitamin D
Hormones
2016
Prolactinoma
Dopamine Agonists
Pituitary Neoplasms
Neoplasms
Therapeutics
26 Citations (Scopus)

Effect of pasireotide on glucose- and growth hormone-related biomarkers in patients with inadequately controlled acromegaly

Schmid, H. A., Brue, T., Colao, A., Gadelha, M. R., Shimon, I., Kapur, K., Pedroncelli, A. M. & Fleseriu, M., Feb 23 2016, (Accepted/In press) In : Endocrine. p. 1-10 10 p.

Research output: Contribution to journalArticle

Acromegaly
Growth Hormone
Insulin-Like Growth Factor Binding Protein 2
Biomarkers
Glucose
8 Citations (Scopus)

Late-night salivary cortisol may be valuable for assessing treatment response in patients with Cushing’s disease: 12-month, Phase III pasireotide study

Findling, J. W., Fleseriu, M., Newell-Price, J., Petersenn, S., Pivonello, R., Kandra, A., Pedroncelli, A. M. & Biller, B. M. K., May 21 2016, (Accepted/In press) In : Endocrine. p. 1-8 8 p.

Research output: Contribution to journalArticle

Pituitary ACTH Hypersecretion
Hydrocortisone
Therapeutics
pasireotide
Cushing Syndrome
16 Citations (Scopus)

Pasireotide: A novel treatment for patients with acromegaly

Cuevas-Ramos, D. & Fleseriu, M., Jan 11 2016, In : Drug Design, Development and Therapy. 10, p. 227-239 13 p.

Research output: Contribution to journalArticle

Acromegaly
Somatostatin Receptors
Octreotide
Therapeutics
Ligands
8 Citations (Scopus)

Safety and tolerability of pasireotide long-acting release in acromegaly—results from the acromegaly, open-label, multicenter, safety monitoring program for treating patients who have a need to receive medical therapy (ACCESS) study

Fleseriu, M., Rusch, E., Geer, E. B. & On Behalf Of The Access Study Investigators, B. O. T. A. S. I., Nov 28 2016, (Accepted/In press) In : Endocrine. p. 1-9 9 p.

Research output: Contribution to journalArticle

Acromegaly
Safety
Therapeutics
Glycosylated Hemoglobin A
Hyperglycemia
29 Citations (Scopus)
Acromegaly
Octreotide
Somatostatin
Insulin-Like Growth Factor I
Safety
5 Citations (Scopus)

The role of combination medical therapy in the treatment of acromegaly

Lim, D. S. T. & Fleseriu, M., Aug 13 2016, (Accepted/In press) In : Pituitary. p. 1-13 13 p.

Research output: Contribution to journalArticle

Acromegaly
Somatostatin Receptors
Ligands
Somatomedins
Therapeutics
2015
1 Citation (Scopus)

Cushing disease: where do we stand, where are we heading?

Fleseriu, M. & Petersenn, S., Apr 1 2015, In : Pituitary. 18, 2, p. 179-180 2 p.

Research output: Contribution to journalArticle

ACTH-Secreting Pituitary Adenoma
Pituitary ACTH Hypersecretion
Adenoma
3 Citations (Scopus)

Discovery of Cushing’s Syndrome After Bariatric Surgery: Multicenter Series of 16 Patients

Javorsky, B. R., Carroll, T. B., Tritos, N. A., Salvatori, R., Heaney, A. P., Fleseriu, M., Biller, B. M. K. & Findling, J. W., Dec 1 2015, In : Obesity Surgery. 25, 12, p. 2306-2313 8 p.

Research output: Contribution to journalArticle

Bariatric Surgery
Cushing Syndrome
Diabetes Mellitus
Hypertension
Tertiary Care Centers
25 Citations (Scopus)

Fracture risk in adult patients treated with growth hormone replacement therapy for growth hormone deficiency: A prospective observational cohort study

Mo, D., Fleseriu, M., Qi, R., Jia, N., Child, C. J., Bouillon, R. & Hardin, D. S., May 1 2015, In : The Lancet Diabetes and Endocrinology. 3, 5, p. 331-338 8 p.

Research output: Contribution to journalArticle

Hormone Replacement Therapy
Growth Hormone
Observational Studies
Cohort Studies
Osteoporosis
15 Citations (Scopus)

Giant GH-secreting pituitary adenomas: Management of rare and aggressive pituitary tumors

Shimon, I., Jallad, R. S., Fleseriu, M., Yedinak, C. C., Greenman, Y. & Bronstein, M. D., Jun 1 2015, In : European Journal of Endocrinology. 172, 6, p. 707-713 7 p.

Research output: Contribution to journalArticle

Growth Hormone-Secreting Pituitary Adenoma
Pituitary Neoplasms
Adenoma
Acromegaly
Somatostatin
12 Citations (Scopus)

Medical therapy for Cushing’s disease: adrenal steroidogenesis inhibitors and glucocorticoid receptor blockers

Fleseriu, M. & Petersenn, S., Apr 1 2015, In : Pituitary. 18, 2, p. 245-252 8 p.

Research output: Contribution to journalArticle

Pituitary ACTH Hypersecretion
Glucocorticoid Receptors
Ketoconazole
Therapeutics
Cytochrome P-450 CYP11B2
5 Citations (Scopus)

Medical treatment of acromegaly in pregnancy, highlights on new reports

Fleseriu, M., May 1 2015, In : Endocrine. 49, 3, p. 577-579 3 p.

Research output: Contribution to journalArticle

Hormone Antagonists
Acromegaly
Pregnancy Complications
Human Growth Hormone
Epidermal Growth Factor Receptor
14 Citations (Scopus)

Medical Treatment of Cushing Disease. New Targets, New Hope

Fleseriu, M., Mar 1 2015, In : Endocrinology and Metabolism Clinics of North America. 44, 1, p. 51-70 20 p.

Research output: Contribution to journalArticle

Pituitary ACTH Hypersecretion
Therapeutics
Pharmaceutical Preparations
35 Citations (Scopus)

Osilodrostat, a potent oral 11β-hydroxylase inhibitor: 22-week, prospective, Phase II study in Cushing’s disease

Fleseriu, M., Pivonello, R., Young, J., Hamrahian, A. H., Molitch, M. E., Shimizu, C., Tanaka, T., Shimatsu, A., White, T., Hilliard, A., Tian, C., Sauter, N., Biller, B. M. K. & Bertagna, X., Nov 5 2015, (Accepted/In press) In : Pituitary.

Research output: Contribution to journalArticle

Pituitary ACTH Hypersecretion
Mixed Function Oxygenases
Hydrocortisone
Asthenia
Hirsutism
4 Citations (Scopus)

Pituitary-directed medical therapy in Cushing’s disease

Petersenn, S. & Fleseriu, M., Apr 1 2015, In : Pituitary. 18, 2, p. 238-244 7 p.

Research output: Contribution to journalArticle

Pituitary ACTH Hypersecretion
Therapeutics
Adrenalectomy
Dopamine Agonists
Tretinoin
4 Citations (Scopus)
Pituitary ACTH Hypersecretion
Cavernous Sinus
Magnetic Resonance Imaging
Outcome Assessment (Health Care)
Neoplasms
9 Citations (Scopus)
Acromegaly
Pituitary Neoplasms
Adrenal Insufficiency
Adenoma
Neoplasms

Updates and Highlights in Pituitary Medicine

Ben-Shlomo, A. & Fleseriu, M., Mar 1 2015, In : Endocrinology and Metabolism Clinics of North America. 44, 1, p. xxi-xxiii

Research output: Contribution to journalArticle

Pituitary Diseases
Medicine
2014

Absence of immunostaining for growth hormone in a subset of patients with acromegaly

Schroeder, J. L., Spiotta, A. M., Fleseriu, M., Prayson, R. A., Hamrahian, A. H. & Weil, R. J., 2014, In : Pituitary. 17, 2, p. 103-108 6 p.

Research output: Contribution to journalArticle

Acromegaly
Growth Hormone
Adenoma
Pituitary Neoplasms
Somatomedins
12 Citations (Scopus)

Acromegaly: Assessing the disorder and navigating therapeutic options for treatment

Melmed, S., Kleinberg, D., Bonert, V. & Fleseriu, M., Oct 1 2014, In : Endocrine Practice. 20, p. 7-17 11 p.

Research output: Contribution to journalArticle

Combined Modality Therapy
Biological Models
Continuing Medical Education
Precision Medicine
Acromegaly
9 Citations (Scopus)

Advances in the pharmacotherapy of patients with acromegaly

Fleseriu, M., 2014, In : Discovery medicine. 17, 96, p. 329-338 10 p.

Research output: Contribution to journalArticle

Acromegaly
Drug Therapy
Somatostatin Receptors
Ligands
Therapeutics
17 Citations (Scopus)

Can we predict long-term remission after somatostatin analog withdrawal in patients with acromegaly? Results from a multicenter prospective trial

Vilar, L., Fleseriu, M., Naves, L. A., Albuquerque, J. L., Gadelha, P. S., Dos Santos Faria, M., Nascimento, G. C., Montenegro, R. M. & Montenegro, R. M., 2014, In : Endocrine. 46, 3, p. 577-584 8 p.

Research output: Contribution to journalArticle

Acromegaly
Somatostatin
Multicenter Studies
Octreotide
Therapeutics
1 Citation (Scopus)

Case Report: Reversible cabergoline-associated cardiac valvulopathy post drug discontinuation

McCartney, S., Yedinak, C. C., Dillard, T. H., Wei, K. & Fleseriu, M., Jul 25 2014, In : F1000Research. 3, 3062.1.

Research output: Contribution to journalArticle

Optic Chiasm
Pharmaceutical Preparations
Prolactin
Adenoma
Optics
35 Citations (Scopus)

Changes in plasma ACTH levels and corticotroph tumor size in patients with Cushing's disease during long-term treatment with the glucocorticoid receptor antagonist mifepristone

Fleseriu, M., Findling, J. W., Koch, C. A., Schlaffer, S. M., Buchfelder, M. & Gross, C., Oct 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 10, p. 3718-3727 10 p.

Research output: Contribution to journalArticle

Corticotrophs
Pituitary ACTH Hypersecretion
Mifepristone
Glucocorticoid Receptors
Adrenocorticotropic Hormone
28 Citations (Scopus)

Desafios e armadilhas no diagnóstico da hiperprolactinemia

Translated title of the contribution: Challenges and pitfalls in the diagnosis of hyperprolactinemiaVilar, L., Fleseriu, M. & Bronstein, M. D., 2014, In : Arquivos Brasileiros de Endocrinologia e Metabologia. 58, 1, p. 9-22 14 p.

Research output: Contribution to journalArticle

Hyperprolactinemia
Prolactinoma
Prolactin
Galactorrhea
Pituitary Neoplasms
23 Citations (Scopus)

Extended treatment of Cushing's disease with pasireotide: Results from a 2-year, Phase II study

Boscaro, M., Bertherat, J., Findling, J., Fleseriu, M., Atkinson, A. B., Petersenn, S., Schopohl, J., Snyder, P., Hughes, G., Trovato, A., Hu, K., Maldonado, M. & Biller, B. M. K., 2014, In : Pituitary. 17, 4, p. 320-326 7 p.

Research output: Contribution to journalArticle

Pituitary ACTH Hypersecretion
Hydrocortisone
Therapeutics
Blood Pressure
pasireotide
15 Citations (Scopus)

Factors associated with biochemical remission after microscopic transsphenoidal surgery for acromegaly

Sun, H., Brzana, J., Yedinak, C. C., Gultekin, S., Delashaw, J. B. & Fleseriu, M., Feb 2014, In : Journal of Neurological Surgery, Part B: Skull Base. 75, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

Acromegaly
Growth Hormone
Adenoma
Neoplasms
Reoperation
18 Citations (Scopus)

FRAX score in acromegaly: Does it tell the whole story?

Brzana, J., Yedinak, C. C., Hameed, N. & Fleseriu, M., 2014, In : Clinical Endocrinology. 80, 4, p. 614-616 3 p.

Research output: Contribution to journalArticle

Spinal Fractures
Osteoporotic Fractures
Acromegaly
Photon Absorptiometry
Bone Density
9 Citations (Scopus)

Insight into cardiovascular risk factors in patients with acromegaly

Fleseriu, M., 2014, In : Endocrine. 47, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

Acromegaly
Cardiovascular Diseases
100 Citations (Scopus)

LCI699, a Potent 11β-hydroxylase Inhibitor, normalizes urinary cortisol in patients with Cushing's disease: Results from a multicenter, proof-of-concept study

Bertagna, X., Pivonello, R., Fleseriu, M., Zhang, Y., Robinson, P., Taylor, A., Watson, C. E., Maldonado, M., Hamrahian, A. H., Boscaro, M. & Biller, B. M. K., 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 4, p. 1375-1383 9 p.

Research output: Contribution to journalArticle

Pituitary ACTH Hypersecretion
Mixed Function Oxygenases
Hydrocortisone
Cushing Syndrome
Cortodoxone