• 29756 Citations
  • 83 h-Index
1976 …2021

Research output per year

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Research Output

Article
56 Scopus citations

Absence of clonal beta and gamma T-cell receptor gene rearrangements in a subset of peripheral T-cell lymphomas

Weiss, L. M., Picker, L. J., Grogan, T. M., Warnke, R. A. & Sklar, J., Jan 1 1988, In : American Journal of Pathology. 130, 3, p. 436-442 7 p.

Research output: Contribution to journalArticle

122 Scopus citations

Acute infection and subsequent subclinical reactivation of herpes simplex virus 2 after vaginal inoculation of rhesus macaques

Lo, M., Zhu, J., Hansen, S., Carroll, T., Zuend, C. F., Nöel-Romas, L., Ma, Z. M., Fritts, L., Huang, M. L., Sun, S., Huang, Y., Koelle, D. M., Picker, L., Burgener, A., Corey, L. & Miller, C. J., Jan 1 2019, In : Journal of Virology. 93, 2, e01574-18.

Research output: Contribution to journalArticle

1 Scopus citations

A human lymphocyte homing receptor, the Hermes antigen, is related to cartilage proteoglycan core and link proteins

Goldstein, L. A., Zhou, D. F. H., Picker, L. J., Minty, C. N., Bargatze, R. F., Ding, J. F. & Butcher, E. C., Mar 24 1989, In : Cell. 56, 6, p. 1063-1072 10 p.

Research output: Contribution to journalArticle

379 Scopus citations

Analysis of the immune response and viral evolution during the acute phase of SIV infection

Horton, H., Vogel, T., O'Connor, D., Picker, L. & Watkins, D. I., May 6 2002, In : Vaccine. 20, 15, p. 1927-1932 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Analysis of total human immunodeficiency virus (HIV)-specific CD4+ and CD8+ T-cell responses: Relationship to viral load in untreated HIV infection

Betts, M. R., Ambrozak, D. R., Douek, D. C., Bonhoeffer, S., Brenchley, J. M., Casazza, J. P., Koup, R. A. & Picker, L. J., Dec 17 2001, In : Journal of virology. 75, 24, p. 11983-11991 9 p.

Research output: Contribution to journalArticle

596 Scopus citations

An anti-CD45RO immunotoxin eliminates T cells latently infected with HIV-1 in vitro

McCoig, C., Van Dyke, G., Chou, C. S., Picker, L. J., Ramilo, O. & Vitetta, E. S., Sep 28 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 20, p. 11482-11485 4 p.

Research output: Contribution to journalArticle

27 Scopus citations

An anti-CD45RO immunotoxin kills HIV-latently infected cells from individuals on HAART with little effect on CD8 memory

Saavedra-Lozano, J., Cao, Y., Callison, J., Sarode, R., Sodora, D., Edgar, J., Hatfield, J., Picker, L., Peterson, D., Ramilo, O. & Vitetta, E. S., Feb 22 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 8, p. 2494-2499 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

An anti-CD45RO immunotoxin kills latently infected human immunodeficiency virus (HIV) CD4 T cells in the blood of HIV-positive persons

Saavedra-Lozano, J., McCoig, C., Xu, J., Cao, Y., Keiser, P., Ghetie, V., Siliciano, R. F., Siliciano, J. D., Picker, L. J., Ramilo, O. & Vitetta, E. S., Feb 1 2002, In : Journal of Infectious Diseases. 185, 3, p. 306-314 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

A new perspective of the structural complexity of HCMV-specific T-cell responses

Sylwester, A., Nambiar, K. Z., Caserta, S., Klenerman, P., Picker, L. J. & Kern, F., Sep 1 2016, In : Mechanisms of Ageing and Development. 158, p. 14-22 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Anti-CD19 inhibits the growth of human B-cell tumor lines in vitro and of Daudi cells in SCID mice by inducing cell cycle arrest

Ghetie, M. A., Picker, L. J., Richardson, J. A., Tucker, K., Uhr, J. W. & Vitetta, E. S., Jan 1 1994, In : Blood. 83, 5, p. 1329-1336 8 p.

Research output: Contribution to journalArticle

84 Scopus citations

Antigen-presenting capabilities of human monocytes correlates with their expression of HLA-DS, an Ia determinant distinct from HLA-DR

Gonwa, T. A., Picker, L. J., Raff, H. V., Goyert, S. M., Silver, J. & Stobo, J. D., Mar 24 1983, In : Journal of Immunology. 130, 2, p. 706-711 6 p.

Research output: Contribution to journalArticle

182 Scopus citations

Anti-OX40 (CD134) administration to nonhuman primates: Immunostimulatory effects and toxicokinetic study

Weinberg, A. D., Thalhofer, C., Morris, N., Walker, J. M., Seiss, D., Wong, S., Axthelm, M. K., Picker, L. J. & Urba, W. J., Nov 1 2006, In : Journal of Immunotherapy. 29, 6, p. 575-585 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion

Ranasinghe, S., Lamothe, P. A., Soghoian, D. Z., Kazer, S. W., Cole, M. B., Shalek, A. K., Yosef, N., Jones, R. B., Donaghey, F., Nwonu, C., Jani, P., Clayton, G. M., Crawford, F., White, J., Montoya, A., Power, K., Allen, T. M., Streeck, H., Kaufmann, D. E., Picker, L. & 2 others, Kappler, J. W. & Walker, B. D., Oct 18 2016, In : Immunity. 45, 4, p. 917-930 14 p.

Research output: Contribution to journalArticle

25 Scopus citations

A two-step adhesion cascade for T cell/endothelial cell interactions under flow conditions

Jones, D. A., McIntire, L. V., Smith, C. W. & Picker, L. J., Dec 1994, In : Journal of Clinical Investigation. 94, 6, p. 2443-2450 8 p.

Research output: Contribution to journalArticle

Open Access
152 Scopus citations

A unique phenotype of skin-associated lymphocytes in humans: preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites

Picker, L. J., Michie, S. A., Rott, L. S. & Butcher, E. C., Jan 1 1990, In : American Journal of Pathology. 136, 5, p. 1053-1068 16 p.

Research output: Contribution to journalArticle

463 Scopus citations

Bacterial superantigens induce t cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production

Leung, D. Y. M., Gately, M., Trumble, A., Ferguson-Darnell, B., Schlievert, P. M. & Picker, L. J., Feb 1 1995, In : Journal of Experimental Medicine. 181, 2, p. 747-753 7 p.

Research output: Contribution to journalArticle

279 Scopus citations

B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

Fukazawa, Y., Lum, R., Okoye, A. A., Park, H., Matsuda, K., Bae, J. Y., Hagen, S. I., Shoemaker, R., Deleage, C., Lucero, C., Morcock, D., Swanson, T., Legasse, A. W., Axthelm, M. K., Hesselgesser, J., Geleziunas, R., Hirsch, V. M., Edlefsen, P. T., Piatak, M., Estes, J. D. & 2 others, Lifson, J. D. & Picker, L. J., Feb 2015, In : Nature medicine. 21, 2, p. 132-139 8 p.

Research output: Contribution to journalArticle

267 Scopus citations

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

Hansen, S., Wu, H. L., Burwitz, B., Hughes, C. M., Hammond, K. B., Ventura, A. B., Reed, J. S., Gilbride, R. M., Ainslie, E., Morrow, D. W., Ford, J. C., Selseth, A. N., Pathak, R., Malouli, D., Legasse, A. W., Axthelm, M., Nelson, J., Gillespie, G. M., Walters, L. C., Brackenridge, S. & 8 others, Sharpe, H. R., López, C. A., Frueh, K., Korber, B. T., McMichael, A. J., Gnanakaran, S., Sacha, J. & Picker, L., Feb 12 2016, In : Science. 351, 6274, p. 714-720 7 p.

Research output: Contribution to journalArticle

135 Scopus citations

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

Sylwester, A. W., Mitchell, B. L., Edgar, J. B., Taormina, C., Pelte, C., Ruchti, F., Sleath, P. R., Grabstein, K. H., Hosken, N. A., Kern, F., Nelson, J. A. & Picker, L. J., Sep 5 2005, In : Journal of Experimental Medicine. 202, 5, p. 673-685 13 p.

Research output: Contribution to journalArticle

863 Scopus citations

Cancer dormancy: Isolation and characterization of dormant lymphoma cells

Yefenof, E., Picker, L. J., Scheuermann, R. H., Tucker, T. F., Vitetta, E. S. & Uhr, J. W., Mar 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 5, p. 1829-1833 5 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

CD4+CD8dim T lymphocytes exhibit enhanced cytokine expression, proliferation and cytotoxic activity in response to HCMV and HIV-1 antigens

Suni, M. A., Ghanekar, S. A., Houck, D. W., Maecker, H. T., Wormsley, S. B., Picker, L. J., Moss, R. B. & Maino, V. C., Sep 6 2001, In : European Journal of Immunology. 31, 8, p. 2512-2520 9 p.

Research output: Contribution to journalArticle

92 Scopus citations

CD4+ T-Cell Depletion In Hiv Infection: Mechanisms Of Immunological Failure

Okoye, A. A. & Picker, L. J., Jul 1 2013, In : Immunological reviews. 254, 1, p. 54-64 11 p.

Research output: Contribution to journalArticle

154 Scopus citations

CD44 and its ligand hyaluronate mediate rolling under physiologic flow: A novel lymphocyte-endothelial cell primary adhesion pathway

DeGrendele, H. C., Estess, P., Picker, L. J. & Siegelman, M. H., Mar 1 1996, In : Journal of Experimental Medicine. 183, 3, p. 1119-1130 12 p.

Research output: Contribution to journalArticle

338 Scopus citations

Changes in thymic function with age and during the treatment of HIV infection

Douek, D. C., McFarland, R. D., Keiser, P. H., Gage, E. A., Massey, J. M., Haynes, B. F., Polis, M. A., Haase, A. T., Feinberg, M. B., Sullivan, J. L., Jamieson, B. D., Zack, J. A., Picker, L. J. & Koup, R. A., Dec 17 1998, In : Nature. 396, 6712, p. 690-695 6 p.

Research output: Contribution to journalArticle

1472 Scopus citations

Characterization of a live-attenuated HCMV-based vaccine platform

Caposio, P., van den Worm, S., Crawford, L., Perez, W., Kreklywich, C., Gilbride, R. M., Hughes, C. M., Ventura, A. B., Ratts, R., Marshall, E. E., Malouli, D., Axthelm, M. K., Streblow, D., Nelson, J. A., Picker, L. J., Hansen, S. G. & Früh, K., Dec 1 2019, In : Scientific Reports. 9, 1, 19236.

Research output: Contribution to journalArticle

Open Access

Circulating allergen-reactive T cells from patients with atopic dermatitis and allergic contact dermatitis express the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen

Babi, L. F. S., Picker, L. J., Teresa Perez Soler, M., Drzimalla, K., Flohr, P., Blaser, K. & Hauser, C., May 1 1995, In : Journal of Experimental Medicine. 181, 5, p. 1935-1940 6 p.

Research output: Contribution to journalArticle

Open Access
244 Scopus citations

Clinical, microbiological, and immunological characteristics in HIV-infected subjects at risk for disseminated Mycobacterium avium complex disease: An AACTG Study

MacGregor, R. R., Hafner, R., Wu, J. W., Murphy, R. L., Perlman, D. C., Bermudez, L. E., Inderlied, C. B., Picker, L. J., Wallis, R. S., Andersen, J. W., Mahon, L. F., Koletar, S. L. & Peterson, D. M., Aug 1 2005, In : AIDS Research and Human Retroviruses. 21, 8, p. 689-695 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Clonotypic structure of the human CD4+ memory T cell response to cytomegalovirus

Bitmansour, A. D., Waldrop, S. L., Pitcher, C. J., Khatamzas, E., Kern, F., Maino, V. C. & Picker, L. J., Aug 1 2001, In : Journal of Immunology. 167, 3, p. 1151-1163 13 p.

Research output: Contribution to journalArticle

Open Access
88 Scopus citations

Control of lymphocyte homing

Picker, L. J., Jun 1994, In : Current opinion in immunology. 6, 3, p. 394-406 13 p.

Research output: Contribution to journalArticle

166 Scopus citations

Control of lymphocyte recirculation in man: I. Differential regulation of the peripheral lymph node homing receptor L-selectin on T cells during the virgin to memory cell transition

Picker, L. J., Treer, J. R., Ferguson-Darnell, B., Collins, P. A., Buck, D. & Terstappen, L. W. M. M., Jan 1 1993, In : Journal of Immunology. 150, 3, p. 1105-1121 17 p.

Research output: Contribution to journalArticle

315 Scopus citations

Control of lymphocyte recirculation in man: II. Differential regulation of the cutaneous lymphocyte-associated antigen, a tissue-selective homing receptor for skin-homing T cells

Picker, L. J., Treer, J. R., Ferguson-Darnell, B., Collins, P. A., Bergstresser, P. R. & Terstappen, L. W. M. M., Jan 1 1993, In : Journal of Immunology. 150, 3, p. 1122-1136 15 p.

Research output: Contribution to journalArticle

339 Scopus citations

Coordinate expression of β1 and β2 integrin “activation” epitopes during T cell responses in secondary lymphoid tissue

Picker, L. J., Treer, J. R., Nguyen, M., Terstappen, L. W. M. M., Hogg, N. & Yednock, T., Nov 1993, In : European Journal of Immunology. 23, 11, p. 2751-2757 7 p.

Research output: Contribution to journalArticle

45 Scopus citations

Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques

Burwitz, B., Malouli, D., Bimber, B. N., Reed, J. S., Ventura, A. B., Hancock, M., Uebelhoer, L. S., Bhusari, A., Hammond, K. B., Espinosa Trethewy, R. G., Klug, A., Legasse, A. W., Axthelm, M., Nelson, J., Park, B., Streblow, D., Hansen, S., Picker, L., Frueh, K. & Sacha, J., Nov 1 2016, In : PLoS Pathogens. 12, 11, e1006014.

Research output: Contribution to journalArticle

15 Scopus citations

Cutaneous lymphoid hyperplasia: Immunologic characteristics and assessment of criteria recently proposed as diagnostic of malignant lymphoma

Medeiros, L. J., Picker, L. J., Abel, E. A., Hu, C. H., Hoppe, R. T., Warnke, R. A. & Wood, G. S., Jan 1 1989, In : Journal of the American Academy of Dermatology. 21, 5, p. 929-942 14 p.

Research output: Contribution to journalArticle

47 Scopus citations

Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals

Kern, F., Bunde, T., Faulhaber, N., Kiecker, F., Khatamzas, E., Rudawski, I. M., Pruss, A., Gratama, J. W., Volkmer-Engert, R., Ewert, R., Reinke, P., Volk, H. D. & Picker, L. J., Jun 15 2002, In : Journal of Infectious Diseases. 185, 12, p. 1709-1716 8 p.

Research output: Contribution to journalArticle

206 Scopus citations

Cytomegalovirus pp65 limits dissemination but is dispensable for persistence

Malouli, D., Hansen, S. G., Nakayasu, E. S., Marshall, E. E., Hughes, C. M., Ventura, A. B., Gilbride, R. M., Lewis, M. S., Xu, G., Kreklywich, C., Whizin, N., Fischer, M., Legasse, A. W., Viswanathan, K., Siess, D., Camp, D. G., Axthelm, M. K., Kahl, C., DeFilippis, V. R., Smith, R. D. & 3 others, Streblow, D. N., Picker, L. J. & Früh, K., 2014, In : Journal of Clinical Investigation. 124, 5, p. 1928-1944 17 p.

Research output: Contribution to journalArticle

19 Scopus citations

Cytomegalovirus-specific T cell immunity is maintained in immunosenescent rhesus macaques

Čičin-Šain, L., Sylwester, A. W., Hagen, S. I., Siess, D. C., Currier, N., Legasse, A. W., Fischer, M. B., Koudelka, C. W., Axthelm, M. K., Nikolich-Žugich, J. & Picker, L. J., Aug 15 2011, In : Journal of Immunology. 187, 4, p. 1722-1732 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge

Hansen, S., Womack, J., Scholz, I., Renner, A., Edgel, K. A., Xu, G., Ford, J. C., Grey, M., St. Laurent, B., Turner, J. M., Planer, S., Legasse, A. W., Richie, T. L., Aguiar, J. C., Axthelm, M., Villasante, E. D., Weiss, W., Edlefsen, P. T., Picker, L. & Frueh, K., Jan 1 2019, In : PLoS One. 14, 1, e0210252.

Research output: Contribution to journalArticle

9 Scopus citations

Decay kinetics of human immunodeficiency virus-specific CD8+ T cells in peripheral blood after initiation of highly active antiretroviral therapy

Casazza, J. P., Betts, M. R., Picker, L. J. & Koup, R. A., Jul 7 2001, In : Journal of virology. 75, 14, p. 6508-6516 9 p.

Research output: Contribution to journalArticle

138 Scopus citations

Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates

Messaoudi, I., Warner, J., Fischer, M., Park, B., Hill, B., Mattison, J., Lane, M. A., Roth, G. S., Ingram, D. K., Picker, L. J., Douek, D. C., Mori, M. & Nikolich-Žugich, J., Dec 19 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 51, p. 19448-19453 6 p.

Research output: Contribution to journalArticle

159 Scopus citations

Dendritic cell ontogeny: A human dendritic cell lineage of myeloid origin

Olweus, J., BitMansour, A., Warnke, R., Thompson, P. A., Carballido, J., Picker, L. J. & Lund-Johansen, F., Nov 11 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 23, p. 12551-12556 6 p.

Research output: Contribution to journalArticle

373 Scopus citations

De novo CD5+ diffuse large B-cell lymphomas: A heterogeneous group containing an unusual form of splenic lymphoma

Kroft, S. H., Howard, M. S., Picker, L. J., Ansari, M. Q., Aquino, D. B. & McKenna, R. W., Oct 1 2000, In : American journal of clinical pathology. 114, 4, p. 523-533 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Detection of antigen-specific T cell cytokine expression in whole blood by flow cytometry

Suni, M. A., Picker, L. J. & Maino, V. C., Mar 1 1998, In : Journal of Immunological Methods. 212, 1, p. 89-98 10 p.

Research output: Contribution to journalArticle

243 Scopus citations

Determination of antigen-specific memory/effector CD4+ T cell frequencies by flow cytometry. Evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency

Waldrop, S. L., Pitcher, C. J., Peterson, D. M., Maino, V. C. & Picker, L. J., Apr 1 1997, In : Journal of Clinical Investigation. 99, 7, p. 1739-1750 12 p.

Research output: Contribution to journalArticle

Open Access
472 Scopus citations

Development and homeostasis of T cell memory in rhesus macaque

Pitcher, C. J., Hagen, S. I., Walker, J. M., Lum, R., Mitchell, B. L., Maino, V. C., Axthelm, M. K. & Picker, L. J., Jan 1 2002, In : Journal of Immunology. 168, 1, p. 29-43 15 p.

Research output: Contribution to journalArticle

Open Access
388 Scopus citations

Differences between T cell epitopes recognized after immunization and after infection

Vogel, T. U., Horton, H., Fuller, D. H., Carter, D. K., Vielhuber, K., O'Connor, D. H., Shipley, T., Fuller, J., Sutter, G., Erfle, V., Wilson, N., Picker, L. J. & Watkins, D. I., Oct 15 2002, In : Journal of Immunology. 169, 8, p. 4511-4521 11 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

Differential expression of homing-associated adhesion molecules by T cell subsets in man

Picker, L. J., Terstappen, L. W. M. M., Rott, L. S., Streeter, P. R., Stein, H. & Butcher, E. C., Jan 1 1990, In : Journal of Immunology. 145, 10, p. 3247-3255 9 p.

Research output: Contribution to journalArticle

209 Scopus citations

Differential expression of lymphocyte homing receptors by human memory/effector T cells in pulmonary versus cutaneous immune effector sites

Picker, L. J., Martin, R. J., Trumble, A., Newman, L. S., Collins, P. A., Bergstresser, P. R. & Leung, D. Y. M., Jun 1994, In : European Journal of Immunology. 24, 6, p. 1269-1277 9 p.

Research output: Contribution to journalArticle

164 Scopus citations

Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry

Picker, L. J., Singh, M. K., Zdraveski, Z., Treer, J. R., Waldrop, S. L., Bergstresser, P. R. & Maino, V. C., Jan 1 1995, In : Blood. 86, 4, p. 1408-1419 12 p.

Research output: Contribution to journalArticle

473 Scopus citations