Lev Fedorov

Research Assistant Professor

  • 877 Citations
  • 10 h-Index
1986 …2019
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Research Output 1986 2019

  • 877 Citations
  • 10 h-Index
  • 26 Article
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20 Citations (Scopus)

A comparison of the germline potential of differently aged ES cell lines and their transfected descendants

Fedorov, L., Haegel-Kronenberger, H. & Hirchenhain, J., May 1997, In : Transgenic Research. 6, 3, p. 223-231 9 p.

Research output: Contribution to journalArticle

germ cells
Clone Cells
cell lines
Cell Line
Genes

Analiz khimernykh mysheǐ, poluchennykh putem in''ektsii kletok vnutrenneǐ kletochnoǐ massy v blastotsistu.

Translated title of the contribution: An analysis of chimeric mice obtained by the injection of the inner cell mass into the blastocystMitalipov, S., Fedorov, L. & Strel'chenko, N. S., Sep 1993, In : Ontogenez. 24, 5, p. 5-10 6 p.

Research output: Contribution to journalArticle

Blastocyst Inner Cell Mass
Glucose-6-Phosphate Isomerase
Chimerism
Injections
Blastocyst
19 Citations (Scopus)

Apoptotic signaling proteins: Possible participation in the regulation of vasopressin and catecholamines biosynthesis in the hypothalamus

Chernigovskaya, E. V., Taranukhin, A. G., Glazova, M. V., Yamova, L. A. & Fedorov, L., Dec 2005, In : Histochemistry and Cell Biology. 124, 6, p. 523-533 11 p.

Research output: Contribution to journalArticle

vasopressins
hypothalamus
catecholamine
biosynthesis
Biosynthesis
25 Citations (Scopus)

Bcl-2 determines susceptibility to induction of lung cancer by oncogenic CRaf

Fedorov, L., Tyrsin, O. Y., Papadopoulos, T., Camarero, G., Götz, R. & Rapp, U. R., Nov 1 2002, In : Cancer Research. 62, 21, p. 6297-6303 7 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Neoplasms
Oncogenes
Transgenic Mice
Modifier Genes

Chimeric drift in the erythrocyte population in BALB/c-C57BL/10 and BALB/c-B10.D2 mice

Fedorov, L. & Konyukhov, B. V., Sep 1988, In : Bulletin of Experimental Biology and Medicine. 106, 3, p. 1322-1324 3 p.

Research output: Contribution to journalArticle

Erythrocytes
Population
3 Citations (Scopus)

Complex cytogenetic analysis of early lethality mouse embryos

Tian, Q., Hanlon Newell, A. E., Wang, Y., Olson, S. & Fedorov, L., 2011, In : Chromosome Research. 19, 4, p. 567-574 8 p.

Research output: Contribution to journalArticle

Cytogenetic Analysis
Embryonic Structures
Chromosomes
Genes
Chromosomal Instability

Erratum to: Mosaic variegated aneuploidy in mouse BubR1 deficient embryos and pregnancy loss in human [Chromosome Research, 10.1007/s10577-014-9432-x]

Schmid, M., Steinlein, C., Tian, Q., Hanlon Newell, A. E., Gessler, M., Olson, S., Rosenwald, A., Kneitz, B. & Fedorov, L., Dec 6 2014, In : Chromosome Research. 22, 4

Research output: Contribution to journalArticle

Embryo Loss
Human Chromosomes
Aneuploidy
Pregnancy
Research
45 Citations (Scopus)

Fibroblast Growth Factor Signaling Controls Liver Size in Mice with Humanized Livers

Naugler, W. S., Tarlow, B. D., Fedorov, L., Taylor, M., Pelz, C., Li, B., Darnell, J. & Grompe, M., Sep 1 2015, In : Gastroenterology. 149, 3, p. 728e15-740e15

Research output: Contribution to journalArticle

Fibroblast Growth Factors
Bile Acids and Salts
Liver
Hepatocytes
Body Weight
7 Citations (Scopus)

Generation dependent reduction of tTA expression in double transgenic NZL-2/tTACMV mice

Fedorov, L., Tyrsin, O. Y., Sakk, O., Ganscher, A. & Rapp, U. R., 2001, In : Genesis. 31, 2, p. 78-84 7 p.

Research output: Contribution to journalArticle

Galactosidases
Luciferases
Reporter Genes
Transgenic Mice
Trans-Activators
1 Citation (Scopus)

Genotipicheskiǐ sostav razlichnykh tkaneǐ i organov u agregatsionnykh khimer myshi BALB/c--C57BL/10 i BALB/c--B10.D2 s vyiavlennym khimernym dreǐfom.

Translated title of the contribution: Genotypic status of different tissues and organs in aggregated chimeras of BALB/c----C57BL/10 and BALB/c----B10.D2 with discovered chimeric driftFedorov, L., Oct 1988, In : Byulleten Eksperimentalnoi Biologii i Meditsiny. 106, 10, p. 484-487 4 p.

Research output: Contribution to journalArticle

Blood
Tissue
Chromosomes
Erythrocytes
Electrophoresis
Gametogenesis
Hematopoiesis
Agglomeration
Tissue
Chemical analysis

Interaction of lymphocytes from allophenic mice with spleen colony-forming units of the parental genotype

Fedorov, L., Panteleev, E. I., Irisova, O. A. & Sokolov, V. S., 1993, In : Immunologiya. 6, p. 22-26 5 p.

Research output: Contribution to journalArticle

Stem Cells
Spleen
Genotype
Lymphocytes
Self Tolerance
1 Citation (Scopus)

Izuchenie patogeneza leǐkoza Raushera u agregatsionnykh khimer myshi BALB/C----C57BL/6.

Translated title of the contribution: Pathogenesis of Rauscher leukemia in aggregation chimeras of the BALB/C----C57BL/6 mouseFedorov, L., Klepikov, N. N. & Koniukhov, B. V., Jul 1986, In : Izvestiia Akademii nauk SSSR. Seriia biologicheskaia. 4, p. 561-570 10 p.

Research output: Contribution to journalArticle

Animals
Agglomeration
1 Citation (Scopus)

Khimernyǐ dreǐf v populiatsii éritrotsitov krovi u mysheǐ BALB/c----C57Bl/10 i BALB/c----B10.D2.

Translated title of the contribution: Chimeric drift in blood erythrocyte population in BALB/c----C57BL/10 and BALB----B10.D2 miceFedorov, L. & Koniukhov, B. V., Sep 1988, In : Byulleten Eksperimentalnoi Biologii i Meditsiny. 106, 9, p. 344-347 4 p.

Research output: Contribution to journalArticle

Blood
Erythrocytes
Population
Cellular Structures
Cell Communication
550 Citations (Scopus)

Lack of β-catenin affects mouse development at gastrulation

Haegel, H., Larue, L., Ohsugi, M., Fedorov, L., Herrenknecht, K. & Kemler, R., 1995, In : Development. 121, 11, p. 3529-3537 9 p.

Research output: Contribution to journalArticle

Catenins
Gastrulation
Embryonic Structures
Cadherins
Armadillos
23 Citations (Scopus)

Loss of p53 in CRaf-induced transgenic lung adenoma leads to tumor acceleration and phenotypic switch

Fedorov, L., Papadopoulos, T., Tyrsin, O. Y., Twardzik, T., Götz, R. & Rapp, U. R., May 1 2003, In : Cancer Research. 63, 9, p. 2268-2277 10 p.

Research output: Contribution to journalArticle

Adenoma
Lung
Neoplasms
Cell Dedifferentiation
Animal Disease Models
85 Citations (Scopus)

Lung-targeted expression of the c-Raf-1 kinase in transgenic mice exposes a novel oncogenic character of the wild-type protein

Kerkhoff, E., Fedorov, L., Siefken, R., Walter, A. O., Papadopoulos, T. & Rapp, U. R., Apr 2000, In : Cell Growth and Differentiation. 11, 4, p. 185-190 6 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-raf
Transgenic Mice
Lung
Proteins
Lung Neoplasms
47 Citations (Scopus)

Measles virus-induced immunosuppression in vitro is associated with deregulation of G1 cell cycle control proteins

Engelking, O., Fedorov, L., Lilischkis, R., Ter Meulen, V. & Schneider-Schaulies, S., 1999, In : Journal of General Virology. 80, 7, p. 1599-1608 10 p.

Research output: Contribution to journalArticle

Cell Cycle Proteins
Measles virus
Cell Cycle Checkpoints
Immunosuppression
Lymphocytes
6 Citations (Scopus)

Mosaic variegated aneuploidy in mouse BubR1 deficient embryos and pregnancy loss in human

Schmid, M., Steinlein, C., Tian, Q., Hanlon Newell, A. E., Gessler, M., Olson, S., Rosenwald, A., Kneitz, B. & Fedorov, L., 2014, In : Chromosome Research. 22, 3, p. 375-392 18 p.

Research output: Contribution to journalArticle

Embryo Loss
Aneuploidy
Pregnancy
M Phase Cell Cycle Checkpoints
Chromatids
10 Citations (Scopus)

Renal failure causes early death of bcl-2 deficient mice

Fedorov, L., Schmittwolf, C., Amann, K., Thomas, W. H., Müller, A. M., Schubert, H., Domen, J. & Kneitz, B., Jul 2006, In : Mechanisms of Ageing and Development. 127, 7, p. 600-609 10 p.

Research output: Contribution to journalArticle

Renal Insufficiency
Cause of Death
Polycystic Kidney Diseases
Tissue
Kidney
1 Citation (Scopus)

RHEB1 expression in embryonic and postnatal mouse

Tian, Q., Smart, J. L., Clement, J. H., Wang, Y., Derkatch, A., Schubert, H., Danilchik, M., Marks, D. & Fedorov, L., Dec 26 2015, (Accepted/In press) In : Histochemistry and Cell Biology. p. 1-12 12 p.

Research output: Contribution to journalArticle

Intestines
Embryonic Development
Urinary Bladder
Physiological Phenomena
Telencephalon
5 Citations (Scopus)

RHEB1 insufficiency in aged male mice is associated with stress-induced seizures

Tian, Q., Gromov, P., Clement, J. H., Wang, Y., Riemann, M., Weih, F., Sun, X-X., Dai, M. & Fedorov, L., Sep 10 2017, (Accepted/In press) In : GeroScience. p. 1-14 14 p.

Research output: Contribution to journalArticle

Sirolimus
Seizures
Brain
TOR Serine-Threonine Kinases
Gene Knockout Techniques
8 Citations (Scopus)

STAT3 and SMAD1 signaling in medaka embryonic stem-like cells and blastula embryos

Wagner, T. U., Kraeussling, M., Fedorov, L., Reiss, C., Kneitz, B. & Schartl, M., Jan 1 2009, In : Stem Cells and Development. 18, 1, p. 151-160 10 p.

Research output: Contribution to journalArticle

Oryzias
Blastula
STAT3 Transcription Factor
Embryonic Stem Cells
Embryonic Structures
2 Citations (Scopus)

Taar1 gene variants have a causal role in methamphetamine intake and response and interact with Oprm1

Stafford, A. M., Reed, C., Baba, H., Walter, N. A., Mootz, J. R., Williams, R. W., Neve, K., Fedorov, L., Janowsky, A. & Phillips, T., Jul 9 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Methamphetamine
Genes
Clustered Regularly Interspaced Short Palindromic Repeats
Hot Temperature
Chromosomes, Human, Pair 10
18 Citations (Scopus)

Tet-system for the regulation of gene expression during embryonic development

Fedorov, L., Tyrsin, O. Y., Krenn, V., Chernigovskaya, E. V. & Rapp, U. R., 2001, In : Transgenic Research. 10, 3, p. 247-258 12 p.

Research output: Contribution to journalArticle

gene expression regulation
Gene Expression Regulation
Embryonic Development
embryogenesis
Trans-Activators

T lymphocytes of allophenic mice do not reject spleen colony-forming units of the parental genotypes

Fedorov, L. & Panteleev, E. I., 2000, In : Journal of Hematotherapy and Stem Cell Research. 9, 4, p. 517-523 7 p.

Research output: Contribution to journalArticle

Stem Cells
Spleen
Genotype
T-Lymphocytes
Bone Marrow Cells