Kevin Winthrop

Professor

  • 17115 Citations
  • 58 h-Index
19972020

Research output per year

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Research Output

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Article
2020

An Integrated Analysis of the Safety of Tofacitinib in Psoriatic Arthritis across Phase III and Long-Term Extension Studies with Comparison to Real-World Observational Data

Burmester, G. R., Curtis, J. R., Yun, H., FitzGerald, O., Winthrop, K. L., Azevedo, V. F., Rigby, W. F. C., Kanik, K. S., Wang, C., Biswas, P., Jones, T., Palmetto, N., Hendrikx, T., Menon, S. & Rojo, R., Apr 1 2020, In : Drug Safety. 43, 4, p. 379-392 14 p.

Research output: Contribution to journalArticle

Open Access

Effect of short-term methotrexate discontinuation on rheumatoid arthritis disease activity: post-hoc analysis of two randomized trials

Park, J. K., Kim, M. J., Choi, Y., Winthrop, K., Song, Y. W. & Lee, E. B., Feb 1 2020, In : Clinical Rheumatology. 39, 2, p. 375-379 5 p.

Research output: Contribution to journalArticle

Evaluation of hepatitis B virus in clinical trials of baricitinib in rheumatoid arthritis

Harigai, M., Winthrop, K., Takeuchi, T., Hsieh, T. Y., Chen, Y. M., Smolen, J. S., Burmester, G., Walls, C., Wu, W. S., Dickson, C., Liao, R. & Genovese, M. C., Feb 25 2020, In : RMD Open. 6, 1, e001095.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Immunosuppression and the risk of readmission and mortality in patients with rheumatoid arthritis undergoing hip fracture, abdominopelvic and cardiac surgery

George, M. D., Baker, J. F., Winthrop, K. L., Goldstein, S. D., Alemao, E., Chen, L., Wu, Q., Xie, F. & Curtis, J. R., May 1 2020, In : Annals of the rheumatic diseases. 79, 5, 1 p.

Research output: Contribution to journalArticle

Incidence and prevalence of nontuberculous mycobacterial lung disease in a Large U.S. Managed Care Health Plan, 2008-2015

Winthrop, K. L., Marras, T. K., Adjemian, J., Zhang, H., Wang, P. & Zhang, Q., Jan 1 2020, In : Annals of the American Thoracic Society. 17, 2, p. 178-185 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Safety profile of baricitinib in Japanese patients with active rheumatoid arthritis with over 1.6 years median time in treatment: An integrated analysis of Phases 2 and 3 trials

Harigai, M., Takeuchi, T., Smolen, J. S., Winthrop, K. L., Nishikawa, A., Rooney, T. P., Saifan, C. G., Issa, M., Isaka, Y., Akashi, N., Ishii, T. & Tanaka, Y., Jan 2 2020, In : Modern Rheumatology. 30, 1, p. 36-43 8 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Who Needs a Corona?

Winthrop, K. L., Jan 1 2020, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

Open Access

‘Lady Windermere's counterpart? Pulmonary nontuberculous mycobacteria in men with bronchiectasis

Ku, J. H., Ranches, G., Siegel, S. A. R. & Winthrop, K. L., Feb 2020, In : Diagnostic Microbiology and Infectious Disease. 96, 2, 114916.

Research output: Contribution to journalArticle

1 Scopus citations
2019

A systematic review and meta-analysis of infection risk with small molecule JAK inhibitors in rheumatoid arthritis

Bechman, K., Subesinghe, S., Norton, S., Atzeni, F., Galli, M., Cope, A. P., Winthrop, K. L. & Galloway, J. B., Oct 1 2019, In : Rheumatology (United Kingdom). 58, 10, p. 1755-1766 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Comparative risks of chronic inhaled corticosteroids and macrolides for bronchiectasis

Henkle, E., Curtis, J. R., Chen, L., Chan, B., Aksamit, T. R., Daley, C. L., Griffith, D. E. & Winthrop, K. L., Jul 1 2019, In : The European respiratory journal. 54, 1

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Direct-acting antivirals for hepatitis C: Predictors of early discontinuation in the real world

De Ávila Machado, M. A., De Moura, C. S., Klein, M., Winthrop, K., Carleton, B., Abrahamowicz, M., Feld, J., Curtis, J. R., Beauchamp, M. E. & Bernatsky, S., Jan 1 2019, In : Journal of Managed Care and Specialty Pharmacy. 25, 6, p. 697-704 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Evaluation of pneumococcal and tetanus vaccine responses in patients with rheumatoid arthritis receiving baricitinib: Results from a long-term extension trial substudy

Winthrop, K. L., Bingham, C. O., Komocsar, W. J., Bradley, J., Issa, M., Klar, R. & Kartman, C. E., Apr 18 2019, In : Arthritis Research and Therapy. 21, 1, 102.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Individualized decision aid for diverse women with lupus nephritis (IDEA-WON): A randomized controlled trial

Singh, J. A., Fraenkel, L., Green, C., Alarcón, G. S., Barton, J., Saag, K. G., Hanrahan, L. M., Raymond, S. C., Kimberly, R. P., Leong, A. L., Reyes, E., Street, R. L., Suarez-Almazor, M. E., Eakin, G. S., Marrow, L., Morgan, C. J., Caro, B., Sloan, J. A., Jandali, B., Garcia, S. R. & 8 others, Grossman, J., Winthrop, K., Trupin, L., Dall’era, M., Meara, A., Rizvi, T., Chatham, W. W. & Yazdany, J., May 1 2019, In : PLoS medicine. 16, 5, e1002800.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Long-term safety of certolizumab pegol in rheumatoid arthritis, axial spondyloarthritis, psoriatic arthritis, psoriasis and Crohn's disease: A pooled analysis of 11 317 patients across clinical trials

Curtis, J. R., Mariette, X., Gaujoux-Viala, C., Blauvelt, A., Kvien, T. K., Sandborn, W. J., Winthrop, K., De Longueville, M., Huybrechts, I. & Bykerk, V. P., May 1 2019, In : RMD Open. 5, 1, e000942.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Long-Term Safety of Rituximab in Patients With Rheumatoid Arthritis: Results of a Five-Year Observational Study

Winthrop, K. L., Saag, K., Cascino, M. D., Pei, J., John, A., Jahreis, A., Haselkorn, T. & Furst, D. E., Aug 2019, In : Arthritis Care and Research. 71, 8, p. 993-1003 11 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Practice Patterns of Pneumocystis Pneumonia Prophylaxis in Connective Tissue Diseases: A Survey of Infectious Disease Physicians

Wolfe, R. M., Beekmann, S. E., Polgreen, P. M., Winthrop, K. L. & Peacock, J. E., Oct 5 2019, In : Open Forum Infectious Diseases. 6, 9, ofz315.

Research output: Contribution to journalArticle

Open Access

Prescribing patterns for treatment of mycobacterium avium complex and m. Xenopi pulmonary disease in ontario, canada, 2001–2013

Brode, S. K., Chung, H., Campitelli, M. A., Kwong, J. C., Marchand-Austin, A., Winthrop, K. L., Jamieson, F. B. & Marras, T. K., Jul 2019, In : Emerging infectious diseases. 25, 7, p. 1271-1280 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Risk for Herpes Zoster in Tofacitinib-Treated Rheumatoid Arthritis Patients With and Without Concomitant Methotrexate and Glucocorticoids

Curtis, J. R., Xie, F., Yang, S., Bernatsky, S., Chen, L., Yun, H. & Winthrop, K., Sep 1 2019, In : Arthritis Care and Research. 71, 9, p. 1249-1254 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Safety profile of baricitinib in patients with active rheumatoid arthritis with over 2 years median time in treatment

Smolen, J. S., Genovese, M. C., Takeuchi, T., Hyslop, D. L., Macias, W. L., Rooney, T., Chen, L., Dickson, C. L., Camp, J. R., Cardillo, T. E., Ishii, T. & Winthrop, K., Jan 1 2019, In : Journal of Rheumatology. 46, 1, p. 7-18 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

The clinical features of bronchiectasis associated with alpha-1 antitrypsin deficiency, common variable immunodeficiency and primary ciliary dyskinesia-Results from the U.S. bronchiectasis research registry

Eden, E., Choate, R., Barker, A., Addrizzo-Harris, D., Aksamit, T. R., Daley, C. L., Daniels, M. L. A., DiMango, A., Fennelly, K., Griffith, D. E., Johnson, M. M., Knowles, M. R., Metersky, M. L., Noone, P. G., O'Donnell, A. E., Olivier, K. N., Salathe, M. A., Schmid, A., Thomashow, B., Tino, G. & 2 others, Turino, G. M. & Winthrop, K. L., Jan 1 2019, In : Chronic Obstructive Pulmonary Diseases. 6, 2, p. 145-153 9 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Timing of Abatacept Before Elective Arthroplasty and Risk of Postoperative Outcomes

George, M. D., Baker, J. F., Winthrop, K., Alemao, E., Chen, L., Connolly, S., Hsu, J. Y., Simon, T. A., Wu, Q., Xie, F., Yang, S. & Curtis, J. R., Jan 1 2019, In : Arthritis Care and Research.

Research output: Contribution to journalArticle

3 Scopus citations

Ustekinumab use in patients with severe psoriasis co-infected with hepatitis B and/or C

Siegel, S. A. R., Winthrop, K., Ehst, B. B. & Ortega Loayza, A., Jan 1 2019, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Amikacin liposome inhalation suspension for treatment-refractory lung disease caused by Mycobacterium avium complex (CONVERT) a prospective, open-label, randomized study

Griffith, D. E., Eagle, G., Thomson, R., Aksamit, T. R., Hasegawa, N., Morimoto, K., Addrizzo-Harris, D. J., O'Donnell, A. E., Marras, T. K., Flume, P. A., Loebinger, M. R., Morgan, L., Codecasa, L. R., Hill, A. T., Ruoss, S. J., Yim, J. J., Ringshausen, F. C., Field, S. K., Philley, J. V., Wallace, R. J. & 4 others, Van Ingen, J., Coulter, C., Nezamis, J. & Winthrop, K. L., Dec 15 2018, In : American journal of respiratory and critical care medicine. 198, 12, p. 1559-1569 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Association between inhaled corticosteroid use and pulmonary nontuberculous mycobacterial infection

Liu, V. X., Winthrop, K., Lu, Y., Sharifi, H., Nasiri, H. U. & Ruoss, S. J., Oct 1 2018, In : Annals of the American Thoracic Society. 15, 10, p. 1169-1176 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Characteristics and Health-care Utilization History of Patients With Bronchiectasis in US Medicare Enrollees With Prescription Drug Plans, 2006 to 2014

Henkle, E., Chan, B., Curtis, J. R., Aksamit, T. R., Daley, C. L. & Winthrop, K. L., Dec 2018, In : CHEST. 154, 6, p. 1311-1320 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Effect of oral valproic acid vs placebo for vision loss in patients with autosomal dominant retinitis pigmentosa a randomized phase 2 multicenter placebo-controlled

Birch, D. G., Bernstein, P. S., Iannacone, A., Pennesi, M., Lam, B. L., Heckenlively, J., Csaky, K., Hartnett, M. E., Winthrop, K., Jayasundera, T., Hughbanks-Wheaton, D. K., Warner, J., Yang, P., Fish, G. E., Teske, M. P., Sklaver, N. L., Erker, L., Chegarnov, E., Smith, T., Wahle, A. & 8 others, VanVeldhuisen, P. C., McCormack, J., Lindblad, R., Bramer, S., Rose, S., Zilliox, P., Francis, P. J. & Weleber, R., Aug 1 2018, In : JAMA Ophthalmology. 136, 8, p. 849-856 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Epidemiology of nontuberculous mycobacterial infections in the U.S. Veterans Health Administration

Jones, M. M., Winthrop, K., Nelson, S. D., Duvall, S. L., Patterson, O. V., Nechodom, K. E., Findley, K. E., Radonovich, L. J., Samore, M. H. & Fennelly, K. P., Jun 1 2018, In : PLoS One. 13, 6, 0197976.

Research output: Contribution to journalArticle

3 Scopus citations
35 Scopus citations

Herpes zoster infection in patients with ulcerative colitis receiving tofacitinib

Winthrop, K., Melmed, G. Y., Vermeire, S., Long, M. D., Chan, G., Pedersen, R. D., Lawendy, N., Thorpe, A. J., Nduaka, C. I. & Su, C., Oct 1 2018, In : Inflammatory Bowel Diseases. 24, 10, p. 2258-2265 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Impact of temporary methotrexate discontinuation for 2 weeks on immunogenicity of seasonal influenza vaccination in patients with rheumatoid arthritis: A randomised clinical trial

Park, J. K., Lee, Y. J., Shin, K., Ha, Y. J., Lee, E. Y., Song, Y. W., Choi, Y., Winthrop, K. & Lee, E. B., Jun 1 2018, In : Annals of the Rheumatic Diseases. 77, 6, p. 898-904 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Interaction between B-cell activation factor and methotrexate impacts immunogenicity of seasonal influenza vaccination in patients with rheumatoid arthritis

Park, J. K., Lee, Y. J., Bitoun, S., Winthrop, K., Choi, Y., Lee, E. B. & Mariette, X., Jan 1 2018, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

1 Scopus citations

Multicenter study of QuantiFERON®-TB Gold Plus in patients with active tuberculosis

Horne, D. J., Jones, B. E., Kamada, A., Fukushima, K., Winthrop, K. L., Siegel, S. A. R., Kovacs, A., Anthony, P., Meekin, K. A., Bhat, S., Kerndt, P., Chang, A., Koelle, D. M. & Narita, M., Jun 1 2018, In : International Journal of Tuberculosis and Lung Disease. 22, 6, p. 617-621 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Respire 1: A phase III placebo-controlled randomised trial of ciprofloxacin dry powder for inhalation in non-cystic fibrosis bronchiectasis

De Soyza, A., Aksamit, T., Bandel, T. J., Criollo, M., Stuart Elborn, J., Operschall, E., Polverino, E., Roth, K., Winthrop, K. L. & Wilson, R., Jan 1 2018, In : European Respiratory Journal. 51, 1, 1702052.

Research output: Contribution to journalArticle

70 Scopus citations

Specificity of QuantiFERON-TB plus, a new-generation interferon gamma release assay

Siegel, S. A. R., Cavanaugh, M., Ku, J. H., Kawamura, L. M. & Winthrop, K. L., Dec 2018, In : Journal of Clinical Microbiology. 56, 12, e00629-18.

Research output: Contribution to journalArticle

1 Scopus citations

T-cell–mediated immune response to pneumococcal conjugate vaccine (PCV-13) and tetanus toxoid vaccine in patients with moderate-to-severe psoriasis during tofacitinib treatment

Winthrop, K., Korman, N., Abramovits, W., Rottinghaus, S. T., Tan, H., Gardner, A., Mukwaya, G., Kaur, M. & Valdez, H., Jan 1 2018, (Accepted/In press) In : Journal of the American Academy of Dermatology.

Research output: Contribution to journalArticle

5 Scopus citations

The Italian registry of pulmonary non-tuberculous mycobacteria - IRENE: The study protocol

Aliberti, S., Codecasa, L. R., Gori, A., Sotgiu, G., Spotti, M., Di Biagio, A., Calcagno, A., Nardini, S., Assael, B. M., Tortoli, E., Besozzi, G., Ferrarese, M., Matteelli, A., Girardi, E., De Lorenzo, S., Seia, M., Gramegna, A., Del Prato, B., Terranova, L., Oriano, M. & 20 others, Sverzellati, N., Mirsaeidi, M., Chalmers, J. D., Haworth, C. S., Loebinger, M. R., Aksamit, T., Winthrop, K., Ringshausen, F. C., Previdi, G., Blasi, F., Fusetti, G., Martorana, M., Colella, G., Verga, G., Carbone, G., Damilano, I., Nava, F., Pancini, L., Pasat, A. & Vanoni, N., Aug 9 2018, In : Multidisciplinary Respiratory Medicine. 13, 33.

Research output: Contribution to journalArticle

4 Scopus citations

The prevalence and significance of Staphylococcus aureus in patients with non-cystic fibrosis bronchiectasis

Metersky, M. L., Aksamit, T. R., Barker, A., Choate, R., Daley, C. L., Daniels, L. A., DiMango, A., Eden, E., Griffith, D., Johnson, M., Knowles, M., O'Donnell, A. E., Olivier, K., Salathe, M., Thomashow, B., Tino, G., Turino, G., Winthrop, K. & Mannino, D., Mar 1 2018, In : Annals of the American Thoracic Society. 15, 3, p. 365-370 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

The unmet need in rheumatology: Reports from the targeted therapies meeting 2017

Winthrop, K. L., Strand, V., van der Heijde, D., Mease, P., Crow, M., Weinblatt, M., Bathon, J., Burmester, G. R., Dougados, M., Kay, J., Mariette, X., Van Vollenhoven, R., Sieper, J., Melchers, F., Breedfeld, F. C., Kalden, J., Smolen, J. S. & Furst, D. E., Jan 2018, In : Clinical Immunology. 186, p. 87-93 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Treatment of Mycobacterium abscessus Complex

Strnad, L. & Winthrop, K., Jan 1 2018, In : Seminars in Respiratory and Critical Care Medicine. 39, 3, p. 362-376 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

US Patient-Centered Research Priorities and Roadmap for Bronchiectasis

Henkle, E., Aksamit, T. R., Daley, C. L., Griffith, D. E., O'Donnell, A. E., Quittner, A. L., Malanga, E., Prieto, D., Leitman, A. & Winthrop, K. L., Nov 2018, In : CHEST. 154, 5, p. 1016-1023 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Adult Patients With Bronchiectasis: A First Look at the US Bronchiectasis Research Registry

for the & Bronchiectasis Research Registry Consortium, May 2017, In : CHEST. 151, 5, p. 982-992 11 p.

Research output: Contribution to journalArticle

93 Scopus citations

Disseminated nontuberculous mycobacteria in HIV-infected patients, Oregon, USA, 2007–2012

Varley, C. D., Ku, J. H., Henkle, E., Schafer, S. D. & Winthrop, K., Mar 1 2017, In : Emerging Infectious Diseases. 23, 3, p. 533-535 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Effect of methotrexate discontinuation on efficacy of seasonal influenza vaccination in patients with rheumatoid arthritis: a randomised clinical trial

Park, J. K., Lee, M. A., Lee, E. Y., Song, Y. W., Choi, Y., Winthrop, K. & Lee, E. B., Sep 1 2017, In : Annals of the Rheumatic Diseases. 76, 9, p. 1559-1565 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Frequency of untreated hypogammaglobulinemia in bronchiectasis

Ruffner, M. A., Aksamit, T. R., Thomashow, B., Choate, R., DiMango, A., Turino, G. M., O'Donnell, A. E., Johnson, M. M., Olivier, K. N., Fennelly, K., Daley, C. L., Winthrop, K., Metersky, M. L., Salathe, M. A., Knowles, M. R., Daniels, M. L. A., Noone, P. G., Tino, G., Griffith, D. E. & Sullivan, K. E., Jul 1 2017, In : Annals of Allergy, Asthma and Immunology. 119, 1, p. 83-85 3 p.

Research output: Contribution to journalArticle

Herpes Zoster and the Risk of Stroke in Patients With Autoimmune Diseases

Calabrese, L. H., Xie, F., Yun, H., Winthrop, K., Baddley, J. W., Calabrese, C. & Curtis, J. R., Feb 1 2017, In : Arthritis and Rheumatology. 69, 2, p. 439-446 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy

Winthrop, K., Curtis, J. R., Lindsey, S., Tanaka, Y., Yamaoka, K., Valdez, H., Hirose, T., Nduaka, C. I., Wang, L., Mendelsohn, A. M., Fan, H., Chen, C. & Bananis, E., 2017, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

55 Scopus citations

Herpes zoster in psoriasis patients treated with tofacitinib

Winthrop, K., Lebwohl, M., Cohen, A. D., Weinberg, J. M., Tyring, S. K., Rottinghaus, S. T., Gupta, P., Ito, K., Tan, H., Kaur, M., Egeberg, A., Mallbris, L. & Valdez, H., Aug 1 2017, In : Journal of the American Academy of Dermatology. 77, 2, p. 302-309 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Infections from seven clinical trials of ixekizumab, an anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriasis

Papp, K. A., Bachelez, H., Blauvelt, A., Winthrop, K., Romiti, R., Ohtsuki, M., Acharya, N., Braun, D. K., Mallbris, L., Zhao, F., Xu, W., Walls, C. D. & Strober, B., Jan 1 2017, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

15 Scopus citations

Longterm effectiveness of herpes zoster vaccine among patients with autoimmune and inflammatory diseases

Yun, H., Xie, F., Baddley, J. W., Winthrop, K., Saag, K. G. & Curtis, J. R., Jul 1 2017, In : Journal of Rheumatology. 44, 7, p. 1083-1087 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Long-term outcomes in a population-based cohort with respiratory nontuberculous mycobacteria isolation

Henkle, E., Novosad, S. A., Shafer, S., Hedberg, K., Siegel, S. A. R., Ku, J., Varley, C., Rebecca Prevots, D., Marras, T. K. & Winthrop, K. L., Jul 2017, In : Annals of the American Thoracic Society. 14, 7, p. 1120-1128 9 p.

Research output: Contribution to journalArticle

8 Scopus citations