Kent Thornburg

Professor

  • 8505 Citations
  • 45 h-Index
1972 …2020

Research output per year

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Research Output

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2020

Leptin and insulin in young adulthood are associated with weight in infancy

Simeoni, U., Osmond, C., Garay, R., Buffat, C., Boubred, F., Chagnaud, C., Jouve, E., Audebert, C., Antoine, J. M. & Thornburg, K., Jan 1 2020, In : Journal of Endocrinology. 244, 2, p. 249-259 11 p.

Research output: Contribution to journalArticle

2019

Activator protein-1 and caspase 8 mediate p38α MAPK-dependent cardiomyocyte apoptosis induced by palmitic acid

Oh, C. C., Lee, J., D’Souza, K., Zhang, W., Migrino, R. Q., Thornburg, K. & Reaven, P., Jan 1 2019, In : Apoptosis.

Research output: Contribution to journalArticle

1 Scopus citations

Down-regulation of MEIS1 promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes

Lindgren, I. M., Drake, R. R., Chattergoon, N. N. & Thornburg, K. L., Jun 1 2019, In : FASEB Journal. 33, 6, p. 7417-7426 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
5 Scopus citations

Right ventricular remodeling in response to volume overload in fetal sheep

Karamlou, T., Giraud, G. D., McKeogh, D., Jonker, S. S., Shen, I., Ungerleider, R. M. & Thornburg, K. L., May 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 5, p. H985-H991

Research output: Contribution to journalArticle

Thyroid hormone receptor function in maturing ovine cardiomyocytes

Chattergoon, N. N., Louey, S., Scanlan, T., Lindgren, I., Giraud, G. D. & Thornburg, K. L., Apr 15 2019, In : Journal of Physiology. 597, 8, p. 2163-2176 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

What's so special about lipid transport in the human placenta?

Thornburg, K. L., Kolahi, K. S. & Valent, A. M., Oct 1 2019, In : Journal of Physiology. 597, 19, p. 4863-4864 2 p.

Research output: Contribution to journalArticle

2018

A cautionary response to SMFM statement: pharmacological treatment of gestational diabetes

Barbour, L. A., Scifres, C., Valent, A. M., Friedman, J. E., Buchanan, T. A., Coustan, D., Aagaard, K., Thornburg, K., Catalano, P. M., Galan, H. L., Hay, W. W., Frias, A., Shankar, K., Simmons, R. A., Moses, R. G., Sacks, D. A. & Loeken, M. R., Jan 1 2018, (Accepted/In press) In : American Journal of Obstetrics and Gynecology.

Research output: Contribution to journalArticle

21 Scopus citations

Inflammatory determinants of pregravid obesity in placenta and peripheral blood

Sureshchandra, S., Marshall, N. E., Wilson, R. M., Barr, T., Rais, M., Purnell, J. Q., Thornburg, K. L. & Messaoudi, I., Aug 7 2018, In : Frontiers in Physiology. 9, AUG, 1089.

Research output: Contribution to journalArticle

14 Scopus citations

Prenatal Development and Adolescent Obesity: Two Distinct Pathways to Diabetes in Adulthood

Boone-Heinonen, J., Sacks, R. M., Takemoto, E. E., Hooker, E. R., DIeckmann, N. F., Harrod, C. S. & Thornburg, K. L., Apr 2018, In : Childhood Obesity. 14, 3, p. 173-181 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Real-time microscopic assessment of fatty acid uptake kinetics in the human term placenta

Kolahi, K. S., Valent, A. M. & Thornburg, K., Dec 1 2018, In : Placenta. 72-73, p. 1-9 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Maternal Nutritional Milieu and Neonatal Outcomes: Connecting the Dots

Thornburg, K. & Valent, A. M., Jan 1 2018, (Accepted/In press) In : Journal of Pediatrics.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Blood flow patterns underlie developmental heart defects

Midgett, M., Thornburg, K. & Rugonyi, S., Mar 13 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 312, 3, p. H632-H642

Research output: Contribution to journalArticle

20 Scopus citations

Cytotrophoblast, Not Syncytiotrophoblast, Dominates Glycolysis and Oxidative Phosphorylation in Human Term Placenta

Kolahi, K. S., Valent, A. M. & Thornburg, K., Feb 23 2017, In : Scientific Reports. 7, 42941.

Research output: Contribution to journalArticle

16 Scopus citations

IFPA meeting 2016 workshop report III: Decidua-trophoblast interactions; trophoblast implantation and invasion; immunology at the maternal-fetal interface; placental inflammation

Aplin, J. D., Beristain, A., DaSilva-Arnold, S., Dunk, C., Duzyj, C., Golos, T. G., Kemmerling, U., Knöfler, M., Mitchell, M. D., Olson, D. M., Petroff, M., Pollheimer, J., Reyes, L., Schedin, P., Soares, M. J., Stencel-Baerenwald, J., Thornburg, K. & Lash, G. E., Apr 13 2017, (Accepted/In press) In : Placenta.

Research output: Contribution to journalArticle

Maternal pregravid obesity remodels the DNA methylation landscape of cord blood monocytes disrupting their inflammatory program

Sureshchandra, S., Wilson, R. M., Rais, M., Marshall, N., Purnell, J., Thornburg, K. & Messaoudi, I., Oct 15 2017, In : Journal of Immunology. 199, 8, p. 2729-2744 16 p.

Research output: Contribution to journalArticle

11 Scopus citations

Maternal weight gain regulates omega-3 fatty acids in male, not female, neonates: A cross-sectional study

O'Tierney-Ginn, P. F., Gillingham, M., Fowler, J., Brass, E., Marshall, N. & Thornburg, K., 2017, In : Reproductive Sciences. 24, 4, p. 560-567 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade

Lue, H. W., Podolak, J., Kolahi, K., Cheng, L., Rao, S., Garg, D., Xue, C. H., Rantala, J. K., Tyner, J., Thornburg, K., Martinez-Acevedo, A., Liu, J-J., Amling, C., Truillet, C., Louie, S. M., Anderson, K. E., Evans, M. J., O’Donnell, V. B., Nomura, D. K., Drake, J. M. & 2 others, Ritz, A. & Thomas, G., Oct 15 2017, In : Genes and Development. 31, 20, p. 2067-2084 18 p.

Research output: Contribution to journalArticle

17 Scopus citations

Neonatal fatty acid profiles are correlated with infant growth measures at 6 months

O’Tierney-Ginn, P. F., Davina, D., Gillingham, M., Barker, D. J. P., Morris, C. & Thornburg, K., Mar 16 2017, (Accepted/In press) In : Journal of Developmental Origins of Health and Disease. p. 1-9 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Poorer maternal diet quality and increased birth weight*

Grandy, M., Snowden, J., Heinonen, J., Purnell, J., Thornburg, K. & Marshall, N., May 17 2017, (Accepted/In press) In : Journal of Maternal-Fetal and Neonatal Medicine. p. 1-7 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

The neuropeptide galanin promotes an anti-thrombotic phenotype on endocardial endothelial cells from heart failure patients

Tyrrell, C., Toyooka, A., Khan, F., Thornburg, K., Mudd, J. & Hasan, W., Sep 1 2017, In : Autonomic Neuroscience: Basic and Clinical. 206, p. 35-42 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Thyroid hormone and pancreas development: diabetes culprit or innocent bystander?

Thornburg, K. & Chattergoon, N., Jun 1 2017, In : Journal of Physiology. 595, 11, p. 3261 1 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Biological features of placental programming

Thornburg, K., Kolahi, K., Pierce, M., Valent, A., Drake, R. & Louey, S., Dec 1 2016, In : Placenta. 48, p. S47-S53

Research output: Contribution to journalArticle

19 Scopus citations

Changes in dynamic embryonic heart wall motion in response to outflow tract banding measured using video densitometry

Stovall, S., Midgett, M., Thornburg, K. & Rugonyi, S., Nov 1 2016, In : Journal of Biomedical Optics. 21, 11, 116003.

Research output: Contribution to journalArticle

2 Scopus citations

Comparison of multiple methods to measure maternal fat mass in late gestation

Marshall, N., Murphy, E. J., King, J. C., Haas, E. K., Lim, J. Y., Wiedrick, J., Thornburg, K. & Purnell, J., Apr 1 2016, In : American Journal of Clinical Nutrition. 103, 4, p. 1055-1063 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Developmental Origins, Epigenetics, and Equity: Moving Upstream

Wallack, L. & Thornburg, K., May 1 2016, In : Maternal and Child Health Journal. 20, 5, p. 935-940 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Furosemide Pharmacokinetics in Adult Rats become Abnormal with an Adverse Intrauterine Environment and Modulated by a Post-Weaning High-Fat Diet

Dubois, B. N., Pearson, J., Mahmood, T., Thornburg, K. & Cherala, G., Jun 1 2016, In : Basic and Clinical Pharmacology and Toxicology. 118, 6, p. 432-439 8 p.

Research output: Contribution to journalArticle

Long-term cardiovascular outcome following fetal anaemia and intrauterine transfusion: A cohort study

Wallace, A. H., Dalziel, S. R., Cowan, B. R., Young, A. A., Thornburg, K. & Harding, J. E., Sep 23 2016, (Accepted/In press) In : Archives of Disease in Childhood.

Research output: Contribution to journalArticle

6 Scopus citations

Overcoming birth weight: Can physical activity mitigate birth weight-related differences in adiposity?

Boone-Heinonen, J., Markwardt, S., Fortmann, S. P. & Thornburg, K. L., Jun 1 2016, In : Pediatric Obesity. 11, 3, p. 166-173 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Placental origins of chronic disease

Burton, G. J., Fowden, A. L. & Thornburg, K., Oct 1 2016, In : Physiological Reviews. 96, 4, p. 1509-1565 57 p.

Research output: Contribution to journalArticle

128 Scopus citations

Prenatal and maternal characteristics and later risk for coronary heart disease among women

Eriksson, J. G., Kajantie, E., Thornburg, K. & Osmond, C., Mar 1 2016, In : European Journal of Preventive Cardiology. 23, 4, p. 385-390 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
22 Scopus citations
2015

Endocardial endothelial dysfunction progressively disrupts initially anti then pro-thrombotic pathways in heart failure mice

Schoner, A., Tyrrell, C., Wu, M., Gelow, J., Hayes, A. A., Lindner, J., Thornburg, K. & Hasan, W., Nov 1 2015, In : PLoS One. 10, 11, e0142940.

Research output: Contribution to journalArticle

8 Scopus citations

IFPA meeting 2015 workshop report: Mechanistic role of the placenta in fetal programming; biomarkers of placental function and complications of pregnancy; late onset fetal growth restriction surveillance and monitoring

Andraweera, P. H., Bobek, G., Bowen, C., Burton, G. J., Correa Frigerio, P., Chaparro, A., Dickinson, H., Duncombe, G., Hyett, J., Illanes, S. E., Johnstone, E., Kumar, S., Morgan, T., Myers, J., Orefice, R., Roberts, C. T., Salafia, C. M., Thornburg, K., Whitehead, C. L. & Bainbridge, S. A., Oct 14 2015, (Accepted/In press) In : Placenta.

Research output: Contribution to journalArticle

4 Scopus citations

Increased fetal myocardial sensitivity to insulin-stimulated glucose metabolism during ovine fetal growth restriction

Barry, J. S., Rozance, P. J., Brown, L. D., Anthony, R. V., Thornburg, K. & Hay, W. W., 2015, In : Experimental Biology and Medicine. 241, 8, p. 839-847 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Influence of high fat diet and resveratrol supplementation on placental fatty acid uptake in the Japanese macaque

O'Tierney-Ginn, P., Roberts, V., Gillingham, M., Walker, J., Glazebrook, P. A., Thornburg, K. L., Grove, K. & Frias, A. E., Aug 1 2015, In : Placenta. 36, 8, p. 903-910 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Letter to Hiroko Nishimura

Thornburg, K. L., Sep 1 2015, Physiologist, 58, 5 1 p.

Research output: Contribution to specialist publicationArticle

Maternal obesity alters immune cell frequencies and responses in umbilical cord blood samples

Wilson, R. M., Marshall, N. E., Jeske, D. R., Purnell, J. Q., Thornburg, K. & Messaoudi, I., Jun 1 2015, In : Pediatric Allergy and Immunology. 26, 4, p. 344-351 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

The placenta is the center of the chronic disease universe

Thornburg, K. L. & Marshall, N., Oct 1 2015, In : American journal of obstetrics and gynecology. 213, 4, p. S14-S20

Research output: Contribution to journalArticle

31 Scopus citations

Timing of cardiomyocyte growth, maturation, and attrition in perinatal sheep

Jonker, S. S., Louey, S., Giraud, G. D., Thornburg, K. L. & Faber, J. J., Oct 1 2015, In : FASEB Journal. 29, 10, p. 4346-4357 12 p.

Research output: Contribution to journalArticle

25 Scopus citations
2014

3D imaging of the early embryonic chicken heart with focused ion beam scanning electron microscopy

Rennie, M. Y., Gahan, C. G., López, C. S., Thornburg, K. L. & Rugonyi, S., Aug 2014, In : Microscopy and Microanalysis. 20, 4, p. 1111-1119 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Beneficial and cautionary outcomes of resveratrol supplementation in pregnant nonhuman primates

Roberts, V. H. J., Pound, L. D., Thorn, S. R., Gillingham, M. B., Thornburg, K. L., Friedman, J. E., Frias, A. E. & Grove, K. L., Jun 2014, In : FASEB Journal. 28, 6, p. 2466-2477 12 p.

Research output: Contribution to journalArticle

70 Scopus citations

P38α mitogen-activated kinase mediates cardiomyocyte apoptosis induced by palmitate

Oh, C. C., Nguy, M. Q., Schwenke, D. C., Migrino, R. Q., Thornburg, K. & Reaven, P., Jul 18 2014, In : Biochemical and Biophysical Research Communications. 450, 1, p. 628-633 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Perinatal growth restriction decreases diuretic action of furosemide in adult rats

Dubois, B. N., Pearson, J., Mahmood, T., Nguyen, D., Thornburg, K. & Cherala, G., Apr 5 2014, In : European Journal of Pharmacology. 728, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
13 Scopus citations
2013
20 Scopus citations

Foetal and childhood growth and asthma in adult life

Barker, D. J. P., Osmond, C., Forsén, T. J., Thornburg, K. L., Kajantie, E. & Eriksson, J. G., Jun 10 2013, In : Acta Paediatrica, International Journal of Paediatrics. 102, 7, p. 732-738 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Hyperglycemia slows embryonic growth and suppresses cell cycle via cyclin D1 and p21

Scott-Drechsel, D. E., Rugonyi, S., Marks, D. L., Thornburg, K. L. & Hinds, M. T., Jan 1 2013, In : Diabetes. 62, 1, p. 234-242 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Maternal cotyledons at birth predict blood pressure in childhood

Barker, D., Osmond, C., Grant, S., Thornburg, K. L., Cooper, C., Ring, S. & Davey-Smith, G., Aug 2013, In : Placenta. 34, 8, p. 672-675 4 p.

Research output: Contribution to journalArticle

15 Scopus citations