Ke-Zhong Shen

Research Assistant Professor

  • 2634 Citations
  • 28 h-Index
1989 …2019

Research output per year

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Research Output

  • 2634 Citations
  • 28 h-Index
  • 56 Article
2019

Phosphoinositol metabolism affects AMP kinase-dependent K-ATP currents in rat substantia nigra dopamine neurons

Shen, K-Z., Munhall, A. C. & Johnson, S., Mar 1 2019, In : Brain Research. 1706, p. 32-40 9 p.

Research output: Contribution to journalArticle

2017
3 Scopus citations
2016

AMP kinase regulates ligand-gated K-ATP channels in substantia nigra dopamine neurons

Shen, K-Z., Wu, Y. N., Munhall, A. C. & Johnson, S., Aug 25 2016, In : Neuroscience. 330, p. 219-228 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

AMP kinase regulates K-ATP currents evoked by NMDA receptor stimulation in rat subthalamic nucleus neurons

Shen, K. Z., Yakhnitsa, V., Munhall, A. C. & Johnson, S. W., Aug 22 2014, In : Neuroscience. 274, p. 138-152 15 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013
6 Scopus citations
2012
5 Scopus citations
1 Scopus citations
8 Scopus citations
2010
30 Scopus citations
2008

5-HT inhibits synaptic transmission in rat subthalamic nucleus neurons in vitro

Shen, K. Z. & Johnson, S. W., Feb 19 2008, In : Neuroscience. 151, 4, p. 1029-1033 5 p.

Research output: Contribution to journalArticle

21 Scopus citations
14 Scopus citations
2007

Multiple conductances are modulated by 5-HT receptor subtypes in rat subthalamic nucleus neurons

Shen, K. Z., Kozell, L. B. & Johnson, S. W., Sep 21 2007, In : Neuroscience. 148, 4, p. 996-1003 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
2006

Subthalamic stimulation evokes complex EPSCs in the rat substantia nigra pars reticulata in vitro

Shen, K. Z. & Johnson, S. W., Jun 15 2006, In : Journal of Physiology. 573, 3, p. 697-709 13 p.

Research output: Contribution to journalArticle

35 Scopus citations
2005

Dopamine depletion alters responses to glutamate and GABA in the rat subthalamic nucleus

Shen, K. Z. & Johnson, S. W., Feb 8 2005, In : NeuroReport. 16, 2, p. 171-174 4 p.

Research output: Contribution to journalArticle

43 Scopus citations

NMDA enhances a depolarization-activated inward current in subthalamic neurons

Zhu, Z. T., Munhall, A., Shen, K. Z. & Johnson, S. W., Sep 1 2005, In : Neuropharmacology. 49, 3, p. 317-327 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
2004
51 Scopus citations
2003

Dopamine receptor supersensitivity in rat subthalamus after 6-hydroxydopamine lesions

Shen, K. Z., Zhu, Z. T., Munhall, A. & Johnson, S. W., Dec 1 2003, In : European Journal of Neuroscience. 18, 11, p. 2967-2974 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
13 Scopus citations

Presynaptic inhibition of synaptic transmission by adenosine in rat subthalamic nucleus in vitro

Shen, K. Z. & Johnson, S. W., Jan 15 2003, In : Neuroscience. 116, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Synaptic Plasticity in Rat Subthalamic Nucleus Induced by High-Frequency Stimulation

Shen, K. Z., Zhu, Z. T., Munhall, A. & Johnson, S. W., Dec 15 2003, In : Synapse. 50, 4, p. 314-319 6 p.

Research output: Contribution to journalArticle

78 Scopus citations
2002

Excitatory effects of dopamine on subthalamic nucleus neurons: In vitro study of rats pretreated with 6-hydroxydopamine and levodopa

Zhu, Z., Bartol, M., Shen, K. & Johnson, S. W., Jul 26 2002, In : Brain research. 945, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

67 Scopus citations

Pharmacological identification of inward current evoked by dopamine in rat subthalamic neurons in vitro

Zhu, Z. T., Shen, K. Z. & Johnson, S. W., May 27 2002, In : Neuropharmacology. 42, 6, p. 772-781 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Presynaptic modulation of synaptic transmission by opioid receptor in rat subthalamic nucleus in vitro

Shen, K. Z. & Johnson, S. W., May 15 2002, In : Journal of Physiology. 541, 1, p. 219-230 12 p.

Research output: Contribution to journalArticle

31 Scopus citations
2001
9 Scopus citations

Presynaptic GABAB receptors inhibit synaptic inputs to rat subthalamic neurons

Shen, K. Z. & Johnson, S. W., Dec 18 2001, In : Neuroscience. 108, 3, p. 431-436 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
2000
113 Scopus citations
1999
26 Scopus citations
1998

Aromatic residues affecting permeation and gating in dSlo BK channels

Lagrutta, A. A., Shen, K. Z., Rivard, A., North, R. A. & Adelman, J. P., Mar 18 1998, In : Pflugers Archiv European Journal of Physiology. 435, 5, p. 731-739 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Sodium pump evokes high density pump currents in rat midbrain dopamine neurons

Shen, K. Z. & Johnson, S. W., Oct 15 1998, In : Journal of Physiology. 512, 2, p. 449-457 9 p.

Research output: Contribution to journalArticle

17 Scopus citations
1997

L-arginine potentiates GABA-mediated synaptic transmission by a nitric oxide-independent mechanism in rat dopamine neurons

Shen, K. Z., Cox, B. A. & Johnson, S. W., May 26 1997, In : Neuroscience. 79, 3, p. 649-658 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
76 Scopus citations
1996

3α-hydroxy-3β-trifluoromethyl-5α-pregnan-20-one (Co 2-1970): A partial agonist at the neuroactive steroid site of the γ-Aminobutyric acidA receptor

Hawkinson, J. E., Drewe, J. A., Kimbrough, C. L., Chen, J. S., Hogenkamp, D. J., Lan, N. C., Gee, K. W., Shen, K. Z., Whittemore, E. R. & Woodward, R. M., May 1 1996, In : Molecular pharmacology. 49, 5, p. 897-906 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Inhibition of morphine tolerance by NMDA receptor antagonists in the formalin test

Lutfy, K., Shen, K. Z., Woodward, R. M. & Weber, E., Aug 26 1996, In : Brain research. 731, 1-2, p. 171-181 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Pharmacology of ACEA-1416: A potent systemically active NMDA receptor glycine site antagonist

Ilyin, V. I., Whittemore, E. R., Tran, M., Shen, K. Z., Cai, S. X., Kher, S. M., Keana, J. F. W., Weber, E. & Woodward, R. M., Aug 29 1996, In : European Journal of Pharmacology. 310, 2-3, p. 107-114 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Sulfonylurea-sensitive potassium current evoked by sodium-loading in rat midbrain dopamine neurons

Seutin, V., Shen, K. Z., North, R. A. & Johnson, S. W., Apr 1996, In : Neuroscience. 71, 3, p. 709-719 11 p.

Research output: Contribution to journalArticle

24 Scopus citations
1995

Blockade of morphine tolerance by ACEA-1328, a novel NMDA receptor/glycine site antagonist

Lutfy, K., Shen, K. Z., Kwon, I. S., Cai, S. X., Woodward, R. M., Keana, J. F. W. & Weber, E., Jan 24 1995, In : European Journal of Pharmacology. 273, 1-2, p. 187-189 3 p.

Research output: Contribution to journalArticle

45 Scopus citations
1994

Functional differences among alternatively spliced variants of Slowpoke, a Drosophila calcium-activated potassium channel

Lagrutta, A., Shen, K. Z., North, R. A. & Adelman, J. P., Aug 12 1994, In : Journal of Biological Chemistry. 269, 32, p. 20347-20351 5 p.

Research output: Contribution to journalArticle

148 Scopus citations

Tetraethylammonium block of Slowpoke calcium-activated potassium channels expressed in Xenopus oocytes: Evidence for tetrameric channel formation

Shen, K. Z., Lagrutta, A., Davies, N. W., Standen, N. B., Adelman, J. P. & North, R. A., Mar 1 1994, In : Pflügers Archiv European Journal of Physiology. 426, 5, p. 440-445 6 p.

Research output: Contribution to journalArticle

155 Scopus citations
1993

Common ionic mechanisms of excitation by substance P and other transmitters in guinea‐pig submucosal neurones.

Shen, K. Z. & Surprenant, A., Mar 1 1993, In : The Journal of Physiology. 462, 1, p. 483-501 19 p.

Research output: Contribution to journalArticle

36 Scopus citations

Excitation of rat locus coeruleus neurons by adenosine 5'-triphosphate: Ionic mechanism and receptor characterization

Shen, K. Z. & North, R. A., Jan 1 1993, In : Journal of Neuroscience. 13, 3, p. 894-899 6 p.

Research output: Contribution to journalArticle

82 Scopus citations

Somatostatin‐mediated inhibitory postsynaptic potential in sympathetically denervated guinea‐pig submucosal neurones.

Shen, K. Z. & Surprenant, A., Oct 1 1993, In : The Journal of Physiology. 470, 1, p. 619-635 17 p.

Research output: Contribution to journalArticle

29 Scopus citations
1992

5-hydroxytryptamine is a fast excitatory transmitter at 5-HT3 receptors in rat amygdala

Sugita, S., Shen, K. Z. & North, R. A., Jan 1992, In : Neuron. 8, 1, p. 199-203 5 p.

Research output: Contribution to journalArticle

155 Scopus citations

Calcium-activated potassium channels expressed from cloned complementary DNAs

Adelman, J. P., Shen, K. Z., Kavanaugh, M. P., Warren, R. A., Wu, Y. N., Lagrutta, A., Bond, C. T. & Alan North, R., Aug 1992, In : Neuron. 9, 2, p. 209-216 8 p.

Research output: Contribution to journalArticle

414 Scopus citations

Muscarine increases cation conductance and decreases potassium conductance in rat locus coeruleus neurones.

Shen, K. Z. & North, R. A., Sep 1 1992, In : The Journal of Physiology. 455, 1, p. 471-485 15 p.

Research output: Contribution to journalArticle

75 Scopus citations

Potassium channels opened by noradrenaline and other transmitters in excised membrane patches of guinea‐pig submucosal neurones.

Shen, K. Z., North, R. A. & Surprenant, A., Jan 1 1992, In : The Journal of Physiology. 445, 1, p. 581-599 19 p.

Research output: Contribution to journalArticle

41 Scopus citations

Substance P opens cation channels and closes potassium channels in rat locus coeruleus neurons

Shen, K. Z. & North, R. A., Sep 1992, In : Neuroscience. 50, 2, p. 345-353 9 p.

Research output: Contribution to journalArticle

108 Scopus citations
1991
22 Scopus citations

Observations on single ion channels affected by inhibitory transmitters in guinea pig submucous plexus neurones

Shen, K. Z., Surprenant, A. & North, R. A., May 1 1991, In : Journal of the Autonomic Nervous System. 33, 2, 1 p.

Research output: Contribution to journalArticle

Transmitter regulation of voltage-dependant K+ channels expressed in Xenopus oocytes

Kavanaugh, M. P., Christie, M. J., Osborne, P. B., Busch, A. E., Shen, K. Z., Wu Seeburg, Y. N. P. H., Adelman, J. P. & North, R. A., Jan 1 1991, In : Biochemical Journal. 277, 3, p. 899-902 4 p.

Research output: Contribution to journalArticle

18 Scopus citations
1990

Cation current activated by hyperpolarization (I(H)) in guinea pig enteric neurons

Galligan, J. J., Tatsumi, H., Shen, K. Z., Surprenant, A. & North, R. A., Dec 1 1990, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 259, 6 22-6, p. G966-G972

Research output: Contribution to journalArticle

55 Scopus citations