Kari Buck

Professor

  • 4711 Citations
  • 35 h-Index
1989 …2021
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Research Output 1989 2018

  • 4711 Citations
  • 35 h-Index
  • 92 Article
  • 3 Chapter
  • 1 Editorial
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Article
2002
59 Citations (Scopus)

Expression profiling identifies strain-specific changes associated with ethanol withdrawal in mice

Daniels, G. M. & Buck, K., Jan 2002, In : Genes, Brain and Behavior. 1, 1, p. 35-45 11 p.

Research output: Contribution to journalArticle

Ethanol
Inbred C57BL Mouse
Inbred DBA Mouse
Genes
Mitogen-Activated Protein Kinases
63 Citations (Scopus)

Harnessing the mouse to unravel the genetics of human disease

Phillips, T., Belknap, J., Hitzemann, R., Buck, K., Cunningham, C. & Crabbe, J. J., Jan 2002, In : Genes, Brain and Behavior. 1, 1, p. 14-26 13 p.

Research output: Contribution to journalArticle

Inborn Genetic Diseases
Genes
Quantitative Trait Loci
Viral Genes
Mutagenesis
15 Citations (Scopus)

In silico discovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databases.

Marshall, K. E., Godden, E. L., Yang, F., Burgers, S., Buck, K. & Sikela, J. M., 2002, In : Genome Biology. 3, 12

Research output: Contribution to journalArticle

Quantitative Trait Loci
Genetic Association Studies
Computer Simulation
quantitative trait loci
genome
55 Citations (Scopus)

Mapping murine loci for physical dependence on ethanol

Buck, K., Rademacher, B. L., Metten, P. & Crabbe, J. J., 2002, In : Psychopharmacology. 160, 4, p. 398-407 10 p.

Research output: Contribution to journalArticle

Ethanol
Quantitative Trait Loci
Seizures
Human Chromosomes
Genes
45 Citations (Scopus)

Multiple cross mapping (MCM) markedly improves the localization of a QTL for ethanol-induced activation

Hitzemann, R., Malmanger, B., Cooper, S., Coulombe, S., Reed, C., Demarest, K., Koyner, J., Cipp, L., Flint, J., Talbot, C., Rademacher, B., Buck, K. & McCaughran, J., Nov 2002, In : Genes, Brain and Behavior. 1, 4, p. 214-222 9 p.

Research output: Contribution to journalArticle

Ethanol
Chromosomes, Human, Pair 1
Inbred Strains Mice
Microsatellite Repeats
Genetic Recombination
2001
24 Citations (Scopus)

Alcohol actions on GABAA receptors: From protein structure to mouse behavior

Ueno, S., Harris, R. A., Messing, R. O., Sanchez-Perez, A. M., Hodge, C. W., McMahon, T., Wang, D., Mehmert, K. K., Kelley, S. P., Haywood, A., Olive, M. F., Buck, K., Hood, H. M., Blednov, Y., Findlay, G. & Mascia, M. P., 2001, In : Alcoholism: Clinical and Experimental Research. 25, 5 SUPPL.

Research output: Contribution to journalArticle

GABA-A Receptors
Alcohols
Proteins
Aminobutyrates
Glycine Receptors
47 Citations (Scopus)
Chromosome Mapping
Quantitative Trait Loci
Alcohols
Genes
Pentobarbital
26 Citations (Scopus)

Genomewide search for epistasis in a complex trait: Pentobarbital withdrawal convulsions in mice

Hood, H. M., Belknap, J., Crabbe, J. J. & Buck, K., 2001, In : Behavior Genetics. 31, 1, p. 93-100 8 p.

Research output: Contribution to journalArticle

epistasis
pentobarbital
Pentobarbital
seizures
modifiers (genes)
71 Citations (Scopus)

QTL analysis and genomewide mutagenesis in mice: Complementary genetic approaches to the dissection of complex traits

Belknap, J., Hitzemann, R., Crabbe, J. J., Phillips, T., Buck, K. & Williams, R. W., 2001, In : Behavior Genetics. 31, 1, p. 5-15 11 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
dissection
mutagenesis
Mutagenesis
Dissection
2000
34 Citations (Scopus)
Hypothermia
GABA-A Receptors
Ataxia
Genetic Predisposition to Disease
Ethanol
13 Citations (Scopus)

GABA(A) receptor β2 subunit mRNA content is differentially regulated in ethanol-dependent DBA/2J and C57BL/6J mice

Reilly, M. T. & Buck, K., Nov 1 2000, In : Neurochemistry International. 37, 5-6, p. 443-452 10 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Inbred C57BL Mouse
Ethanol
Messenger RNA
Cerebellum
20 Citations (Scopus)
Quinpirole
Quantitative Trait Loci
Dopamine
Locomotion
Dopamine D2 Receptors
1999
212 Citations (Scopus)

Identifying genes for alcohol and drug sensitivity: Recent progress and future directions

Crabbe, J. J., Phillips, T., Buck, K., Cunningham, C. & Belknap, J., Apr 1 1999, In : Trends in Neurosciences. 22, 4, p. 173-179 7 p.

Research output: Contribution to journalArticle

Alcohols
Quantitative Trait Loci
Pharmaceutical Preparations
Genes
Direction compound
59 Citations (Scopus)

Quantitative trait loci affecting risk for pentobarbital withdrawal map near alcohol withdrawal loci on mouse Chromosomes 1, 4, and 11

Buck, K., Metten, P., Belknap, J. & Crabbe, J. J., 1999, In : Mammalian Genome. 10, 5, p. 431-437 7 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 4
Chromosomes, Human, Pair 1
Quantitative Trait Loci
Pentobarbital
1998
91 Citations (Scopus)

Genes on mouse chromosomes 2 and 9 determine variation in ethanol consumption

Phillips, T., Belknap, J., Buck, K. & Cunningham, C., 1998, In : Mammalian Genome. 9, 12, p. 936-941 6 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 9
Chromosomes, Human, Pair 2
Ethanol
Genes
Quantitative Trait Loci
42 Citations (Scopus)

Genetic association of a GABA(A) receptor γ2 subunit variant with severity of acute physiological dependence on alcohol

Buck, K. & Hood, H. M., 1998, In : Mammalian Genome. 9, 12, p. 975-978 4 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Alcoholism
Quantitative Trait Loci
Alcohols
Genes
1 Citation (Scopus)

In vivo generation of chimeras

Buck, K. & Amara, S. G., 1998, In : Methods. 296, p. 466-475 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Recent progress toward the identification of genes related to risk for alcoholism

Buck, K., 1998, In : Mammalian Genome. 9, 12, p. 927-928 2 p.

Research output: Contribution to journalArticle

Heritable Quantitative Trait
Alcoholism
Genes
1997
7 Citations (Scopus)

Quantitative Trait Loci: Mapping Drug and Alcohol-Related Genes

Crabbe, J. J., Belknap, J., Metten, P., Grisel, J. E. & Buck, K., 1997, In : Advances in Pharmacology. 42, C, p. 1033-1037 5 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Alcohols
Pharmaceutical Preparations
Genes
235 Citations (Scopus)

Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice

Buck, K., Metten, P., Belknap, J. & Crabbe, J. J., 1997, In : Journal of Neuroscience. 17, 10, p. 3946-3955 10 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Genetic Predisposition to Disease
Alcohols
Alcoholism
Chromosomes, Human, Pair 11
1996
3 Citations (Scopus)

Discrete structural domains and cell-specific expression determine functional selectivity of the dopamine and norepinephrine transporters.

Buck, K., Lorang, D. & Amara, S. G., 1996, In : NIDA research monograph. 161, p. 154-175 22 p.

Research output: Contribution to journalArticle

Norepinephrine Plasma Membrane Transport Proteins
Dopamine Plasma Membrane Transport Proteins
Mood Disorders
Antidepressive Agents
Catecholamines
49 Citations (Scopus)

Molecular genetic analysis of the role of GABAergic systems in the behavioral and cellular actions of alcohol

Buck, K., May 1996, In : Behavior Genetics. 26, 3, p. 313-323 11 p.

Research output: Contribution to journalArticle

genetic analysis
molecular genetics
genetic techniques and protocols
Molecular Biology
alcohol
17 Citations (Scopus)
Gene expression regulation
Alcohol Withdrawal Delirium
Animal Behavior
Gene Expression Regulation
GABA-A Receptors
5 Citations (Scopus)

Strategies for identifying genes underlying drug abuse susceptibility.

Crabbe, J. J., Buck, K., Metten, P. & Belknap, J., 1996, In : NIDA research monograph. 161, p. 201-219 19 p.

Research output: Contribution to journalArticle

Substance Withdrawal Syndrome
Inbred Strains Mice
Chromosome Mapping
Genetic Predisposition to Disease
Substance-Related Disorders
1995
88 Citations (Scopus)

Localization to chromosome 10 of a locus influencing morphine analgesia in crosses derived from C57BL/ and DBA/2 strains

Belknap, J., Mogil, J. S., Helms, M. L., Richards, S. P., O'Toole, L. A., Bergeson, S. E. & Buck, K., Jul 28 1995, In : Life Sciences. 57, 10

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 10
Quantitative Trait Loci
Chromosomes
Analgesia
Morphine
13 Citations (Scopus)
Quantitative Trait Loci
Genes
Alcohols
Cloning
Alcoholism
88 Citations (Scopus)
Dopamine Plasma Membrane Transport Proteins
nisoxetine
Antidepressive Agents
Catecholamines
Norepinephrine Plasma Membrane Transport Proteins
1994
188 Citations (Scopus)
1-Methyl-4-phenylpyridinium
Norepinephrine Plasma Membrane Transport Proteins
Dopamine Plasma Membrane Transport Proteins
Catecholamines
Dopamine
361 Citations (Scopus)

Genetic animal models of alcohol and drug abuse

Crabbe, J. J., Belknap, J. & Buck, K., Jun 17 1994, In : Science. 264, 5166, p. 1715-1723 9 p.

Research output: Contribution to journalArticle

Genetic Models
Alcoholism
Substance-Related Disorders
Animal Models
Quantitative Trait Loci
3 Citations (Scopus)

The D2 receptor gene [5]

Crabbe, J. J., Belknap, J. & Buck, K., 1994, In : Science. 266, 5184, p. 352-353 2 p.

Research output: Contribution to journalArticle

Dopamine D2 Receptors
Chromosome Mapping
Alcoholism
Genes
29 Citations (Scopus)
Seizures
Alcohols
Genes
Chromosomes, Human, Pair 2
Alleles
1992
19 Citations (Scopus)

GABAA receptor function and regional analysis of subunit mRNAs in long-sleep and short-sleep mouse brain

Zahniser, N. R., Buck, K., Curella, P., McQuilkin, S. J., Wilson-Shaw, D., Miller, C. L., Klein, R. L., Heidenreich, K. A., Keir, W. J., Sikela, J. M. & Harris, R. A., 1992, In : Molecular Brain Research. 14, 3, p. 196-206 11 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Sleep
Messenger RNA
Brain
Ethanol
1991
22 Citations (Scopus)
GABA-A Receptors
Genes
Polymerase Chain Reaction
Messenger RNA
Chemical analysis
100 Citations (Scopus)
Brain
Seizures
Ethanol
Messenger RNA
GABA-A Receptors
4 Citations (Scopus)

Localization and functional expression of alternatively spliced forms of the GABAA receptor γ2 subunit

Sikela, J. M., Leidenheimer, N. J., Gambarana, C., Buck, K., Lin, L. H., Khan, A. S., Wilson-Shaw, D. & Siegel, R. E., 1991, In : Molecular and Cellular Neuroscience. 2, 4, p. 338-343 6 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Protein Isoforms
Messenger RNA
Oocytes
Cerebral Cortex
20 Citations (Scopus)
Chloride Channels
Benzodiazepines
Seizures
Ethanol
Modulation
160 Citations (Scopus)

Multiple human D5 dopamine receptor genes: A functional receptor and two pseudogenes

Grandy, D., Zhang, Y., Bouvier, C., Zhou, Q. Y., Johnson, R. A., Allen, L., Buck, K., Bunzow, J. R., Salon, J. & Civelli, O., Oct 15 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 20, p. 9175-9179 5 p.

Research output: Contribution to journalArticle

Dopamine D5 Receptors
Pseudogenes
Genes
Dopamine D1 Receptors
Terminator Codon
58 Citations (Scopus)

Neuroadaptive responses to chronic ethanol

Buck, K. & Harris, R. A., 1991, In : Alcoholism: Clinical and Experimental Research. 15, 3, p. 460-470 11 p.

Research output: Contribution to journalArticle

Ethanol
Chloride Channels
Guanine Nucleotides
N-Methylaspartate
Calcium Channels
47 Citations (Scopus)

Reversal of alcohol dependence and tolerance by a single administration of flumazenil

Buck, K., Heim, H. & Harris, R. A., 1991, In : Journal of Pharmacology and Experimental Therapeutics. 257, 3, p. 984-989 6 p.

Research output: Contribution to journalArticle

Flumazenil
Alcoholism
Ethanol
Aptitude
GABA-A Receptors
1990
37 Citations (Scopus)
Chloride Channels
GABA-A Receptors
Benzodiazepines
Ethanol
Muscimol
139 Citations (Scopus)
Chloride Channels
GABA-A Receptors
Benzodiazepines
Ethanol
Muscimol
1989
18 Citations (Scopus)

Fluidization of brain membranes by A2C does not produce anesthesia and does not augment muscimol-stimulated 36Cl- influx

Buck, K., Allan, A. M. & Adron Harris, R., Feb 7 1989, In : European Journal of Pharmacology. 160, 3, p. 359-367 9 p.

Research output: Contribution to journalArticle

Muscimol
Benzyl Alcohol
Anesthesia
Anesthetics
Membranes