Kari Buck

Professor

  • 4845 Citations
  • 35 h-Index
1989 …2020

Research output per year

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Research Output

2020

RNA-Seq Analysis of Genetic and Transcriptome Network Effects of Dual-Trait Selection for Ethanol Preference and Withdrawal Using SOT and NOT Genetic Models

Kozell, L. B., Lockwood, D., Darakjian, P., Edmunds, S., Shepherdson, K., Buck, K. J. & Hitzemann, R., Apr 1 2020, In : Alcoholism: Clinical and Experimental Research. 44, 4, p. 820-830 11 p.

Research output: Contribution to journalArticle

Open Access
2018

Distinct roles for two chromosome 1 loci in ethanol withdrawal, consumption, and conditioned place preference

Kozell, L. B., Denmark, D. L., Nicole, N. A. & Buck, K., Aug 27 2018, In : Frontiers in Genetics. 9, AUG, 323.

Research output: Contribution to journalArticle

2017

A systems approach implicates a brain mitochondrial oxidative homeostasis co-expression network in genetic vulnerability to alcohol withdrawal

Walter, N. A. R., Denmark, D. A. L., Kozell, L. B. & Buck, K. J., Jan 3 2017, In : Frontiers in Genetics. 7, JAN, 218.

Research output: Contribution to journalArticle

3 Scopus citations

Limbic circuitry activation in ethanol withdrawal is regulated by a chromosome 1 locus

Buck, K. J., Chen, G. & Kozell, L. B., Feb 1 2017, In : Alcohol. 58, p. 153-160 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

G Protein-Gated Inwardly Rectifying Potassium Channel Subunit 3 Knock-Out Mice Show Enhanced Ethanol Reward

Tipps, M. E., Raybuck, J. D., Kozell, L. B., Lattal, K. M. & Buck, K., 2016, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

10 Scopus citations

The multiple PDZ domain protein Mpdz/MUPP1 regulates opioid tolerance and opioid-induced hyperalgesia

Donaldson, R., Sun, Y., Liang, D. Y., Zheng, M., Sahbaie, P., Dill, D. L., Peltz, G., Buck, K. & Clark, J. D., Apr 29 2016, In : BMC Genomics. 17, 1, 313.

Research output: Contribution to journalArticle

8 Scopus citations

The Substantia Nigra Pars Reticulata in Sedative-Hypnotic Withdrawal

Kruse, L. C. & Buck, K., May 13 2016, General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions. Elsevier Inc., Vol. 3. p. 345-355 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

Acute Ethanol Withdrawal Impairs Contextual Learning and Enhances Cued Learning

Tipps, M. E., Raybuck, J. D., Buck, K. J. & Lattal, K. M., Feb 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 2, p. 282-290 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

GIRK Channels: A Potential Link Between Learning and Addiction

Tipps, M. E. & Buck, K. J., Jan 1 2015, International Review of Neurobiology - Structure to Function of G Protein-Gated Inwardly Rectifying (GIRK) Channels, 2015. Harris, R. A. & Jenner, P. (eds.). Academic Press Inc., p. 239-277 39 p. (International Review of Neurobiology; vol. 123).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Novel MPDZ/MUPP1 transgenic and knockdown models confirm Mpdz's role in ethanol withdrawal and support its role in voluntary ethanol consumption

Milner, L. C., Shirley, R. L., Kozell, L. B., Walter, N. A., Kruse, L. C., Komiyama, N. H., Grant, S. G. N. & Buck, K. J., Jan 1 2015, In : Addiction Biology. 20, 1, p. 143-147 5 p.

Research output: Contribution to journalArticle

15 Scopus citations
2014

Delay and trace fear conditioning in C57BL/6 and DBA/2 mice: Issues of measurement and performance

Tipps, M. E., Raybuck, J. D., Buck, K. J. & Lattal, K. M., Aug 2014, In : Learning and Memory. 21, 8, p. 380-393 14 p.

Research output: Contribution to journalReview article

18 Scopus citations

Dual-Trait Selection for Ethanol Consumption and Withdrawal: Genetic and Transcriptional Network Effects

Metten, P., Iancu, O. D., Spence, S. E., Walter, N. A. R., Oberbeck, D., Harrington, C. A., Colville, A., Mcweeney, S., Phillips, T. J., Buck, K. J., Crabbe, J. C., Belknap, J. K. & Hitzemann, R. J., Dec 1 2014, In : Alcoholism: Clinical and Experimental Research. 38, 12, p. 2915-2924 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Genetic variability of respiratory complex abundance, organization and activity in mouse brain

Buck, K. J., Walter, N. A. R. & Denmark, D. L., Feb 1 2014, In : Genes, Brain and Behavior. 13, 2, p. 135-143 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mpdz expression in the caudolateral substantia nigra pars reticulata is crucially involved in alcohol withdrawal

Kruse, L. C., Walter, N. A. R. & Buck, K. J., Nov 1 2014, In : Genes, Brain and Behavior. 13, 8, p. 769-776 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
7 Scopus citations
2013

A spontaneous deletion of α-Synuclein is associated with an increase in CB1 mRNA transcript and receptor expression in the hippocampus and amygdala: Effects on alcohol consumption

López-Jiménez, A., Walter, N. A. R., Giné, E., Santos, Á., Echeverry-Alzate, V., Bühler, K. M., Olmos, P., Giezendanner, S., Moratalla, R., Montoliu, L., Buck, K. J. & López-Moreno, J. A., Jun 1 2013, In : Synapse. 67, 6, p. 280-289 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2012

Discovering genes involved in alcohol dependence and other alcohol responses: role of animal models

Buck, K., Milner, L. C., Denmark, D. L., Grant, S. G. N. & Kozell, L. B., 2012, In : Alcohol research : current reviews. 34, 3, p. 367-374 8 p.

Research output: Contribution to journalEditorial

4 Scopus citations
2011

Computational detection of alternative exon usage

Laderas, T. G., Walter, N. A. R., Mooney, M., Vartanian, K., Darakjian, P., Buck, K., Harrington, C. A., Belknap, J., Hitzemann, R. & McWeeney, S. K., Dec 1 2011, In : Frontiers in Neuroscience. MAY, Article 69.

Research output: Contribution to journalArticle

9 Scopus citations

Discovering genes involved in alcohol dependence and other alcohol responses: Role of animal models

Buck, K. J., Milner, L. C., Denmark, D. L., Grant, S. G. N. & Kozell, L. B., Dec 1 2011, In : Alcohol Research and Health. 34, 3, p. 367-374 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Evaluating gene expression in C57BL/6J and DBA/2J mouse striatum using RNA-Seq and microarrays

Bottomly, D., Walter, N. A. R., Hunter, J. E., Darakjian, P., Kawane, S., Buck, K. J., Searles, R. P., Mooney, M., McWeeney, S. K. & Hitzemann, R., Mar 30 2011, In : PloS one. 6, 3, e17820.

Research output: Contribution to journalArticle

137 Scopus citations

Striatal involvement in human alcoholism and alcohol consumption, and withdrawal in animal models

Chen, G., Cuzon Carlson, V. C., Wang, J., Beck, A., Heinz, A., Ron, D., Lovinger, D. M. & Buck, K. J., Oct 1 2011, In : Alcoholism: Clinical and Experimental Research. 35, 10, p. 1739-1748 10 p.

Research output: Contribution to journalReview article

52 Scopus citations

Substantia nigra pars reticulata is crucially involved in barbiturate and ethanol withdrawal in mice

Chen, G., Kozell, L. B. & Buck, K. J., Mar 17 2011, In : Behavioural Brain Research. 218, 1, p. 152-157 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2010

A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models

Ehlers, C. L., Walter, N. A. R., Dick, D. M., Buck, K. J. & Crabbe, J. C., Apr 1 2010, In : Addiction Biology. 15, 2, p. 185-199 15 p.

Research output: Contribution to journalReview article

46 Scopus citations

Identifying Quantitative Trait Loci (QTLs) and Genes (QTGs) for Alcohol-Related Phenotypes in Mice

Milner, L. C. & Buck, K. J., Jan 1 2010, International Review of Neurobiology. C ed. Academic Press Inc., p. 173-204 32 p. (International Review of Neurobiology; vol. 91, no. C).

Research output: Chapter in Book/Report/Conference proceedingChapter

21 Scopus citations

Intraperitoneal catheter placement for pharmacological imaging studies in conscious mice

Boudreau, E., Chen, G., Li, X., Buck, K., Hitzemann, R. & Hickman, D., Jan 1 2010, In : Lab Animal. 39, 1, p. 23-25 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Rostroventral caudate putamen involvement in ethanol withdrawal is influenced by a chromosome 4 locus

Chen, G. & Buck, K. J., Oct 1 2010, In : Genes, Brain and Behavior. 9, 7, p. 768-776 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
2009

Differential activation of limbic circuitry associated with chronic ethanol withdrawal in DBA/2J and C57BL/6J mice

Chen, G., Reilly, M. T., Kozell, L. B., Hitzemann, R. & Buck, K. J., Sep 1 2009, In : Alcohol. 43, 6, p. 411-420 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

High throughput sequencing in mice: A platform comparison identifies a preponderance of cryptic SNPs

Walter, N. A. R., Bottomly, D., Laderas, T., Mooney, M. A., Darakjian, P., Searles, R. P., Harrington, C. A., McWeeney, S. K., Hitzemann, R. & Buck, K. J., Aug 17 2009, In : BMC Genomics. 10, 1 p., 1471.

Research output: Contribution to journalArticle

22 Scopus citations

Mapping a barbiturate withdrawal locus to a 0.44 Mb interval and analysis of a novel null mutant identify a role for Kcnj9 (GIRK3) in withdrawal from pentobarbital, zolpidem, and ethanol

Kozell, L. B., Walter, N. A. R., Milner, L. C., Wickman, K. & Buck, K. J., Sep 16 2009, In : Journal of Neuroscience. 29, 37, p. 11662-11673 12 p.

Research output: Contribution to journalArticle

42 Scopus citations
2008

5-HT2C and GABAB receptors influence handling-induced convulsion severity in chromosome 4 congenic and DBA/2J background strain mice

Reilly, M. T., Milner, L. C., Shirley, R. L., Crabbe, J. C. & Buck, K. J., Mar 10 2008, In : Brain research. 1198, p. 124-131 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

"Higher order" addiction molecular genetics: Convergent data from genome-wide association in humans and mice

Uhl, G. R., Drgon, T., Johnson, C., Fatusin, O. O., Liu, Q. R., Contoreggi, C., Li, C. Y., Buck, K. & Crabbe, J., Jan 1 2008, In : Biochemical Pharmacology. 75, 1, p. 98-111 14 p.

Research output: Contribution to journalArticle

108 Scopus citations

Interval-specific congenic animals for high-resolution quantitative trait loci mapping

Denmark, D. L., Milner, L. C. & Buck, K. J., Dec 1 2008, In : Alcohol Research and Health. 31, 3, p. 266-269 4 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Involvement of the limbic basal ganglia in ethanol withdrawal convulsivity in mice is influenced by a chromosome 4 locus

Chen, G., Kozell, L. B., Hitzemann, R. & Buck, K. J., Sep 24 2008, In : Journal of Neuroscience. 28, 39, p. 9840-9849 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Mapping a locus for alcohol physical dependence and associated withdrawal to a 1.1 Mb interval of mouse chromosome 1 syntenic with human chromosome 1q23.2-23.3

Kozell, L., Belknap, J. K., Hofstetter, J. R., Mayeda, A. & Buck, K. J., Jul 1 2008, In : Genes, Brain and Behavior. 7, 5, p. 560-567 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
14 Scopus citations

Single-nucleotide polymorphism masking

Walter, N. A. R., McWeeney, S. K., Peters, S. T., Belknap, J. K., Hitzemann, R. & Buck, K. J., Dec 1 2008, In : Alcohol Research and Health. 31, 3, p. 270-271 2 p.

Research output: Contribution to journalShort survey

2007

SNPs matter: Impact on detection of differential expression [3]

Walter, N. A. R., McWeeney, S. K., Peters, S. T., Belknap, J. K., Hitzemann, R. & Buck, K. J., Sep 1 2007, In : Nature Methods. 4, 9, p. 679-680 2 p.

Research output: Contribution to journalLetter

55 Scopus citations

Use of a novel mouse genotype to model acute benzodiazepine withdrawal

Metten, P., Buck, K. J., Merrill, C. M., Roberts, A. J., Yu, C. H. & Crabbe, J. C., Jan 1 2007, In : Behavior genetics. 37, 1, p. 160-170 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2006

Fine mapping of a sedative-hypnotic drug withdrawal locus on mouse chromosome 11

Hood, H. M., Metten, P., Crabbe, J. C. & Buck, K. J., Feb 1 2006, In : Genes, Brain and Behavior. 5, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2005
30 Scopus citations

The syntaxin binding protein 1 gene (Stxbp1) is a candidate for an ethanol preference drinking locus on mouse chromosome 2

Fehr, C., Shirley, R. L., Crabbe, J. C., Belknap, J. K., Buck, K. J. & Phillips, T. J., May 1 2005, In : Alcoholism: Clinical and Experimental Research. 29, 5, p. 708-720 13 p.

Research output: Contribution to journalArticle

41 Scopus citations
2004

Mpdz is a quantitative trait gene for drug withdrawal seizures

Shirley, R. L., Walter, N. A. R., Reilly, M. T., Fehr, C. & Buck, K. J., Jul 1 2004, In : Nature Neuroscience. 7, 7, p. 699-700 2 p.

Research output: Contribution to journalArticle

110 Scopus citations

On the integration of alcohol-related quantitative trait loci and gene expression analyses

Hitzemann, R., Reed, C., Malmanger, B., Lawler, M., Hitzemann, B., Cunningham, B., McWeeney, S., Belknap, J., Harrington, C., Buck, K., Phillips, T. & Crabbe, J., Oct 1 2004, In : Alcoholism: Clinical and Experimental Research. 28, 10, p. 1437-1448 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Potential pleiotropic effects of Mpdz on vulnerability to seizures

Fehr, C., Shirley, R. L., Metten, P., Kosobud, A. E. K., Belknap, J. K., Crabbet, J. C. & Buck, K. J., Feb 1 2004, In : Genes, Brain and Behavior. 3, 1, p. 8-19 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Selection for pentobarbital withdrawal severity: Correlated differences in withdrawal from other sedative drugs

Kliethermes, C. L., Metten, P., Belknap, J. K., Buck, K. J. & Crabbe, J. C., May 29 2004, In : Brain research. 1009, 1-2, p. 17-25 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Serotonin 5-HT2 Receptors and Alcohol: Reward, Withdrawal and Discrimination

Buck, K. J., Reilly, M. T., Rogers, L. M., Szeliga, K., Grant, K. & Brodie, M. S., Feb 1 2004, In : Alcoholism: Clinical and Experimental Research. 28, 2, p. 211-216 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

The Collaborative Cross, a community resource for the genetic analysis of complex traits

Churchill, G. A., Airey, D. C., Allayee, H., Angel, J. M., Attie, A. D., Beatty, J., Beavis, W. D., Belknap, J. K., Bennett, B., Berrettini, W., Bleich, A., Bogue, M., Broman, K. W., Buck, K. J., Buckler, E., Burmeister, M., Chesler, E. J., Cheverud, J. M., Clapcote, S., Cook, M. N. & 93 others, Cox, R. D., Crabbe, J. C., Crusio, W. E., Darvasi, A., Deschepper, C. F., Doerge, R. W., Farber, C. R., Forejt, J., Gaile, D., Garlow, S. J., Geiger, H., Gershenfeld, H., Gordon, T., Gu, J., Gu, W., de Haan, G., Hayes, N. L., Heller, C., Himmelbauer, H., Hitzemann, R., Hunter, K., Hsu, H. C., Iraqi, F. A., Ivandic, B., Jacob, H. J., Jansen, R. C., Jepsen, K. J., Johnson, D. K., Johnson, T. E., Kempermann, G., Kendziorski, C., Kotb, M., Kooy, R. F., Llamas, B., Lammert, F., Lassalle, J. M., Lowenstein, P. R., Lu, L., Lusis, A., Manly, K. F., Marcucio, R., Matthews, D., Medrano, J. F., Miller, D. R., Mittleman, G., Mock, B. A., Mogil, J. S., Montagutelli, X., Morahan, G., Morris, D. G., Mott, R., Nadeau, J. H., Nagase, H., Nowakowski, R. S., O'Hara, B. F., Osadchuk, A. V., Page, G. P., Paigen, B., Paigen, K., Palmer, A. A., Pan, H. J., Peltonen-Palotie, L., Peirce, J., Pomp, D., Pravenec, M., Prows, D. R., Qi, Z., Reeves, R. H., Roder, J., Rosen, G. D., Schadt, E. E., Schalkwyk, L. C., Seltzer, Z., Shimomura, K., Shou, S., Sillanpää, M. J., Siracusa, L. D., Snoeck, H. W., Spearow, J. L., Svenson, K., Tarantino, L. M., Threadgill, D., Toth, L. A., Valdar, W., Pardo-Manuel de Villena, F., Warden, C., Whatley, S., Williams, R. W., Wiltshire, T., Yi, N., Zhang, D., Zhang, M. & Zou, F., Nov 2004, In : Nature genetics. 36, 11, p. 1133-1137 5 p.

Research output: Contribution to journalReview article

682 Scopus citations
2003

A strategy for the integration of QTL, gene expression, and sequence analyses

Hitzemann, R., Malmanger, B., Reed, C., Lawler, M., Hitzemann, B., Coulombe, S., Buck, K., Rademacher, B., Walter, N., Polyakov, Y., Sikela, J., Gensler, B., Burgers, S., Williams, R. W., Manly, K., Flint, J. & Talbot, C., Nov 1 2003, In : Mammalian Genome. 14, 11, p. 733-747 15 p.

Research output: Contribution to journalArticle

68 Scopus citations
14 Scopus citations