Joseph El Youssef

Assistant Professor

  • 829 Citations
  • 16 h-Index
20042020

Research output per year

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Research Output

  • 829 Citations
  • 16 h-Index
  • 30 Article
  • 3 Comment/debate
  • 2 Conference contribution
  • 2 Review article

Accuracy of wrist-worn activity monitors during common daily physical activities and types of structured exercise: Evaluation study

Kondama Reddy, R., Pooni, R., Zaharieva, D. P., Senf, B., El Youssef, J., Dassau, E., Doyle, F. J., Clements, M. A., Rickels, M. R., Patton, S. R., Castle, J. R., Riddell, M. C. & Jacobs, P. G., Dec 2018, In : JMIR mHealth and uHealth. 6, 12, e10338.

Research output: Contribution to journalArticle

12 Scopus citations

A controlled study of the effectiveness of an adaptive closed-loop algorithm to minimize corticosteroidinduced stress hyperglycemia in type 1 diabetes

El Castle, J., Youssef, J. R., Branigan, D. L., Massoud, R. G., Breen, M. E., Jacobs, P. G., Bequette, B. W. & Ward, W. K., Jun 1 2013, In : Diabetes Technology and Therapeutics. 15, SUPPL.1, p. S30-S31

Research output: Contribution to journalComment/debate

A controlled study of the effectiveness of an adaptive closed-loop algorithm to minimize corticosteroid-induced stress hyperglycemia in type 1 diabetes

El Youssef, J., Castle, J. R., Branigan, D. L., Massoud, R. G., Breen, M. E., Jacobs, P. G., Bequette, B. W. & Ward, W. K., Nov 2011, In : Journal of Diabetes Science and Technology. 5, 6, p. 1312-1326 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

Adaptive tuning of basal and bolus insulin to reduce postprandial hypoglycemia in a hybrid artificial pancreas

Resalat, N., El Youssef, J., Reddy, R., Castle, J. & Jacobs, P., Aug 1 2019, In : Journal of Process Control. 80, p. 247-254 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

An artificial intelligence decision support system for the management of type 1 diabetes

Tyler, N. S., Mosquera-Lopez, C. M., Wilson, L. M., Dodier, R. H., Branigan, D. L., Gabo, V. B., Guillot, F. H., Hilts, W. W., El Youssef, J., Castle, J. R. & Jacobs, P. G., Jan 1 2020, (Accepted/In press) In : Nature Metabolism.

Research output: Contribution to journalArticle

A novel, stable, aqueous Glucagon formulation using Ferulic acid as an Excipient

Bakhtiani, P. A., Caputo, N., Castle, J. R., Youssef, J. E., Carroll, J. M., David, L. L., Roberts, C. T. & Kenneth, W., Jan 1 2015, In : Journal of Diabetes Science and Technology. 9, 1, p. 17-23 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

A review of artificial pancreas technologies with an emphasis on bi-hormonal therapy

Bakhtiani, P. A., Zhao, L. M., El Youssef, J., Castle, J. R. & Ward, W. K., Dec 2013, In : Diabetes, Obesity and Metabolism. 15, 12, p. 1065-1070 6 p.

Research output: Contribution to journalReview article

49 Scopus citations

A review of closed-loop algorithms for glycemic control in the treatment of type 1 diabetes

El Youssef, J., Castle, J. & Ward, W. K., Mar 1 2009, In : Algorithms. 2, 1, p. 518-532 15 p.

Research output: Contribution to journalReview article

35 Scopus citations

A statistical virtual patient population for the glucoregulatory system in type 1 diabetes with integrated exercise model

Resalat, N., El Youssef, J., Tyler, N., Castle, J. & Jacobs, P., Jan 1 2019, In : PloS one. 14, 7, e0217301.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Automated control of an adaptive bihormonal, dual-sensor artificial pancreas and evaluation during inpatient studies

Jacobs, P. G., El Youssef, J., Castle, J., Bakhtiani, P., Branigan, D., Breen, M., Bauer, D., Preiser, N., Leonard, G., Stonex, T. & Ward, W. K., Oct 1 2014, In : IEEE Transactions on Biomedical Engineering. 61, 10, p. 2569-2581 13 p., 6814769.

Research output: Contribution to journalArticle

52 Scopus citations

Biochemical stabilization of glucagon at alkaline pH

Caputo, N., Jackson, M. A., Castle, J. R., El Youssef, J., Bakhtiani, P. A., Bergstrom, C. P., Carroll, J. M., Breen, M. E., Leonard, G. L., David, L. L., Roberts, C. T. & Ward, W. K., Jan 1 2014, In : Diabetes Technology and Therapeutics. 16, 11, p. 747-758 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Continuous glucose monitoring in subjects with type 1 diabetes: Improvement in accuracy by correcting for background current

Youssef, J. E., Castle, J. R., Engle, J. M., Massoud, R. G. & Ward, W. K., Nov 1 2010, In : Diabetes Technology and Therapeutics. 12, 11, p. 921-928 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Design of a dual-hormone model predictive control for artificial pancreas with exercise model

Resalat, N., Youssef, J. E., Reddy, R. & Jacobs, P. G., Oct 13 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., p. 2270-2273 4 p. 7591182. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2016-October).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Development of a fully automated closed loop artificial pancreas control system with dual pump delivery of insulin and glucagon

Jacobs, P. G., Youssef, J. E., Castle, J. R., Engle, J. M., Branigan, D. L., Johnson, P., Massoud, R., Kamath, A. & Ward, W. K., Dec 26 2011, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. p. 397-400 4 p. 6090127. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Scopus citations

Discomfort from an alkaline formulation delivered subcutaneously in humans: Albumin at pH 7 versus pH 10

Ward, W. K., Castle, J. R., Branigan, D. L., Massoud, R. G. & El Youssef, J., Jun 14 2012, In : Clinical Drug Investigation. 32, 7, p. 433-438 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Effect of Aerobic and Resistance Exercise on Glycemic Control in Adults With Type 1 Diabetes

Reddy, R., Wittenberg, A., Castle, J., El Youssef, J., Winters-Stone, K., Gillingham, M. & Jacobs, P., Jan 1 2018, (Accepted/In press) In : Canadian Journal of Diabetes.

Research output: Contribution to journalArticle

3 Scopus citations

Effect of repeated glucagon doses on hepatic glycogen in type 1 Diabetes: Implications for a bihormonal Closed-Loop system

Castle, J. R., Youssef, J. E., Bakhtiani, P. A., Cai, Y., Stobbe, J. M., Branigan, D., Ramsey, K., Jacobs, P., Reddy, R., Woods, M. & Ward, W. K., Nov 2015, In : Diabetes care. 38, 11, p. 2115-2119 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Evaluation of model complexity in model predictive control within an exercise-enabled artificial pancreas

Resalat, N., El Youssef, J., Reddy, R. & Jacobs, P., Jul 1 2017, In : IFAC-PapersOnLine. 50, 1, p. 7756-7761 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
2 Scopus citations

Factors affecting the success of glucagon delivered during an automated closed-loop system in type 1 diabetes

Bakhtiani, P. A., El Youssef, J., Duell, A. K., Branigan, D. L., Jacobs, P. G., Lasarev, M. R., Castle, J. R. & Ward, W. K., Jan 1 2015, In : Journal of Diabetes and Its Complications. 29, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Factors influencing the effectiveness of glucagon for preventing hypoglycemia

Castle, J. R., Engle, J. M., El Youssef, J., Massoud, R. G. & Ward, W. K., Nov 2010, In : Journal of Diabetes Science and Technology. 4, 6, p. 1305-1310 6 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

IN CONTROL of type 1 diabetes, despite hypoglycaemia unawareness

El Youssef, J., Nov 1 2016, In : The Lancet Diabetes and Endocrinology. 4, 11, p. 874-875 2 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Incorporating an exercise detection, grading, and hormone dosing algorithm into the artificial pancreas using accelerometry and heart rate

Jacobs, P., Resalat, N., El Youssef, J., Reddy, R., Branigan, D., Preiser, N., Condon, J. & Castle, J., Nov 1 2015, In : Journal of diabetes science and technology. 9, 6, p. 1175-1184 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

In vitro and in vivo evaluation of native glucagon and glucagon analog (MAR-D28) during aging: Lack of cytotoxicity and preservation of hyperglycemic effect

Ward, W. K., Massoud, R. G., Szybala, C. J., Engle, J. M., El Youssef, J., Carroll, J. M., Roberts, C. T. & DiMarchi, R. D., Nov 2010, In : Journal of Diabetes Science and Technology. 4, 6, p. 1311-1321 11 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

Modeling Glucagon Action in Patients with Type 1 Diabetes

Emami, A., El Youssef, J., Rabasa-Lhoret, R., Pineau, J., Castle, J. & Haidar, A., Jul 1 2017, In : IEEE Journal of Biomedical and Health Informatics. 21, 4, p. 1163-1171 9 p., 7517341.

Research output: Contribution to journalArticle

2 Scopus citations

Novel use of glucagon in a closed-loop system for prevention of hypoglycemia in type 1 diabetes

Castle, J. R., Engle, J. M., El Youssef, J., Massoud, R. G., Yuen, K. C. J., Kagan, R. & Ward, W. K., Jun 1 2010, In : Diabetes care. 33, 6, p. 1282-1287 6 p.

Research output: Contribution to journalArticle

181 Scopus citations

Prediction of Hypoglycemia During Aerobic Exercise in Adults With Type 1 Diabetes

Reddy, R., Resalat, N., Wilson, L. M., Castle, J. R., El Youssef, J. & Jacobs, P. G., Sep 1 2019, In : Journal of Diabetes Science and Technology. 13, 5, p. 919-927 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Prolonged inadvertent pravastatin use in pregnancy

Teelucksingh, S., El Youssef, J., Sohan, K. & Ramsewak, S., Mar 1 2004, In : Reproductive Toxicology. 18, 2, p. 299-300 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Quantification of the glycemic response to microdoses of subcutaneous glucagon at varying insulin levels

El Youssef, J., Castle, J. R., Bakhtiani, P. A., Haidar, A., Branigan, D. L., Breen, M. & Ward, W. K., Nov 1 2014, In : Diabetes care. 37, 11, p. 3054-3060 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Randomized outpatient trial of single- and dual-hormone closed-loop systems that adapt to exercise using wearable sensors

Castle, J. R., Youssef, J. E., Wilson, L. M., Reddy, R., Resalat, N., Branigan, D., Ramsey, K., Leitschuh, J., Rajhbeharrysingh, U., Senf, B., Sugerman, S. M., Gabo, V. & Jacobs, P. G., Jul 1 2018, In : Diabetes care. 41, 7, p. 1471-1477 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

Randomized trial of a dual-hormone artificial pancreas with dosing adjustment during exercise compared with no adjustment and sensor-augmented pump therapy

Jacobs, P., El Youssef, J., Reddy, R., Resalat, N., Branigan, D., Condon, J., Preiser, N., Ramsey, K., Jones, M., Edwards, C., Kuehl, K., Leitschuh, J., Rajhbeharrysingh, U. & Castle, J., 2016, (Accepted/In press) In : Diabetes, Obesity and Metabolism.

Research output: Contribution to journalArticle

57 Scopus citations
27 Scopus citations

The accuracy benefit of multiple amperometric glucose sensors in people with type 1 diabetes

Castle, J. R., Pitts, A., Hanavan, K., Muhly, R., El Youssef, J., Hughes-Karvetski, C., Kovatchev, B. & Ward, W. K., Apr 1 2012, In : Diabetes care. 35, 4, p. 706-710 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

The effect of exercise on sleep in adults with type 1 diabetes

Reddy, R., El Youssef, J., Winters-Stone, K., Branigan, D., Leitschuh, J., Castle, J. & Jacobs, P., Feb 1 2018, In : Diabetes, Obesity and Metabolism. 20, 2, p. 443-447 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

The effect of rising vs. falling glucose level on amperometric glucose sensor lag and accuracy in Type1 diabetes

Ward, W. K., Engle, J. M., Branigan, D., El Youssef, J., Massoud, R. G. & Castle, J. R., Aug 1 2012, In : Diabetic Medicine. 29, 8, p. 1067-1073 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Treatment challenges for the young patient with type 1 diabetes

El Youssef, J. & Ward, W. K., Jun 1 2015, In : Diabetes Technology and Therapeutics. 17, 6, p. 367-369 3 p.

Research output: Contribution to journalComment/debate

3 Scopus citations