Joseph Doggett

Assistant Professor

  • 458 Citations
  • 12 h-Index
20082019

Research output per year

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Research Output

  • 458 Citations
  • 12 h-Index
  • 16 Article
  • 6 Chapter
  • 2 Review article
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Article
2008

Lyme disease in Oregon

Doggett, J. S., Kohlhepp, S., Gresbrink, R., Metz, P., Gleaves, C. & Gilbert, D., Jun 1 2008, In : Journal of Clinical Microbiology. 46, 6, p. 2115-2118 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
2011
22 Scopus citations
2012

Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis

Doggett, J. S., Nilsen, A., Forquer, I., Wegmann, K. W., Jones-Brando, L., Yolken, R. H., Bordón, C., Charman, S. A., Katneni, K., Schultz, T., Burrows, J. N., Hinrichs, D. J., Meunier, B., Carruthers, V. B. & Riscoe, M. K., Sep 25 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 39, p. 15936-15941 6 p.

Research output: Contribution to journalArticle

84 Scopus citations

Sontochin as a guide to the development of drugs against chloroquine-resistant malaria

Pou, S., Winter, R. W., Nilsen, A., Kelly, J. X., Li, Y., Doggett, J. S., Riscoe, E. W., Wegmann, K. W., Hinrichs, D. J. & Riscoe, M. K., Jul 1 2012, In : Antimicrobial agents and chemotherapy. 56, 7, p. 3475-3480 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Bumped kinase inhibitor 1294 treats established toxoplasma gondii infection

Doggett, J. S., Ojo, K. K., Fan, E., Maly, D. J. & Van Voorhis, W. C., Jun 2014, In : Antimicrobial agents and chemotherapy. 58, 6, p. 3547-3549 3 p.

Research output: Contribution to journalArticle

36 Scopus citations

Discovery, synthesis, and optimization of antimalarial 4(1 H)-quinolone-3-diarylethers

Nilsen, A., Miley, G. P., Forquer, I. P., Mather, M. W., Katneni, K., Li, Y., Pou, S., Pershing, A. M., Stickles, A. M., Ryan, E., Kelly, J. X., Doggett, J. S., White, K. L., Hinrichs, D. J., Winter, R. W., Charman, S. A., Zakharov, L. N., Bathurst, I., Burrows, J. N., Vaidya, A. B. & 1 others, Riscoe, M. K., May 8 2014, In : Journal of Medicinal Chemistry. 57, 9, p. 3818-3834 17 p.

Research output: Contribution to journalArticle

66 Scopus citations
2015

SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1

Huang, W., Ojo, K. K., Zhang, Z., Rivas, K., Vidadala, R. S. R., Scheele, S., Derocher, A. E., Choi, R., Hulverson, M. A., Barrett, L. K., Bruzual, I., Siddaramaiah, L. K., Kerchner, K. M., Kurnick, M. D., Freiberg, G. M., Kempf, D., Hol, W. G. J., Merritt, E. A., Neckermann, G., De Hostos, E. L. & 6 others, Isoherranen, N., Maly, D. J., Parsons, M., Doggett, J., Van Voorhis, W. C. & Fan, E., Dec 10 2015, In : ACS Medicinal Chemistry Letters. 6, 12, p. 1184-1189 6 p.

Research output: Contribution to journalArticle

23 Scopus citations
2016

Cystic neutrophilic granulomatous mastitis: Association with gram-positive bacilli and corynebacterium

Troxell, M., Gordon, N. T., Doggett, J., Ballard, M., Vetto, J., Pommier, R. & Naik, A., May 1 2016, In : American Journal of Clinical Pathology. 145, 5, p. 635-645 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis

Vidadala, R. S. R., Rivas, K. L., Ojo, K. K., Hulverson, M. A., Zambriski, J. A., Bruzual, I., Schultz, T. L., Huang, W., Zhang, Z., Scheele, S., DeRocher, A. E., Choi, R., Barrett, L. K., Siddaramaiah, L. K., Hol, W. G. J., Fan, E., Merritt, E. A., Parsons, M., Freiberg, G., Marsh, K. & 6 others, Kempf, D. J., Carruthers, V. B., Isoherranen, N., Doggett, J. S., Van Voorhis, W. C. & Maly, D. J., Jul 14 2016, In : Journal of Medicinal Chemistry. 59, 13, p. 6531-6546 16 p.

Research output: Contribution to journalArticle

43 Scopus citations

Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone

Lawres, L. A., Garg, A., Kumar, V., Bruzual, I., Forquer, I. P., Renard, I., Virji, A. Z., Boulard, P., Rodriguez, E. X., Allen, A. J., Pou, S., Wegmann, K. W., Winter, R. W., Nilsen, A., Mao, J., Preston, D. A., Belperron, A. A., Bockenstedt, L. K., Hinrichs, D. J., Riscoe, M. K. & 2 others, Doggett, J. S. & Mamoun, C. B., Jan 1 2016, In : Journal of Experimental Medicine. 213, 7, p. 1307-1318 12 p.

Research output: Contribution to journalArticle

25 Scopus citations
2017

Extended-spectrum antiprotozoal bumped kinase inhibitors: A review

Van Voorhis, W. C., Doggett, J. S., Parsons, M., Hulverson, M. A., Choi, R., Arnold, S. L. M., Riggs, M. W., Hemphill, A., Howe, D. K., Mealey, R. H., Lau, A. O. T., Merritt, E. A., Maly, D. J., Fan, E. & Ojo, K. K., Sep 2017, In : Experimental Parasitology. 180, p. 71-83 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Genetic evidence for cytochrome b Qi site inhibition by 4(1H)-quinolone-3-diarylethers and antimycin in Toxoplasma gondii

Alday, P. H., Bruzual, I., Nilsen, A., Pou, S., Winter, R., Mamoun, C. B., Riscoe, M. & Doggett, J., Feb 1 2017, In : Antimicrobial Agents and Chemotherapy. 61, 2, e01866.

Research output: Contribution to journalArticle

22 Scopus citations
2018

BmGPAC, an antigen capture assay for detection of active babesia microti infection

Thekkiniath, J., Mootien, S., Lawres, L., Perrin, B. A., Gewirtz, M., Krause, P. J., Williams, S., Doggett, J., Ledizet, M. & Mamoun, C. B., Oct 1 2018, In : Journal of Clinical Microbiology. 56, 10, e00067.

Research output: Contribution to journalArticle

3 Scopus citations

Endochin-like quinolones exhibit promising efficacy against neospora caninum in vitro and in experimentally infected pregnant mice

Anghel, N., Balmer, V., Müller, J., Winzer, P., Aguado-Martinez, A., Roozbehani, M., Pou, S., Nilsen, A., Riscoe, M., Doggett, J. & Hemphill, A., Nov 19 2018, In : Frontiers in Veterinary Science. 5, NOV, 285.

Research output: Contribution to journalArticle

2 Scopus citations

Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis

McConnell, E. V., Bruzual, I., Pou, S., Winter, R., Dodean, R. A., Smilkstein, M. J., Krollenbrock, A., Nilsen, A., Zakharov, L. N., Riscoe, M. & Doggett, J., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

7 Scopus citations
2019

Pharmacokinetics and in Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis

Hulverson, M. A., Bruzual, I., Mcconnell, E. V., Huang, W., Vidadala, R. S. R., Choi, R., Arnold, S. L. M., Whitman, G. R., Mccloskey, M. C., Barrett, L. K., Rivas, K. L., Scheele, S., Derocher, A. E., Parsons, M., Ojo, K. K., Maly, D. J., Fan, E., Van Voorhis, W. C. & Doggett, J. S., Jan 1 2019, In : Journal of Infectious Diseases. 219, 9, p. 1464-1473 10 p., jiy664.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations