Joseph Doggett

Assistant Professor

  • 386 Citations
  • 11 h-Index
20082019
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Fingerprint Dive into the research topics where Joseph Doggett is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Toxoplasmosis Medicine & Life Sciences
Toxoplasma Medicine & Life Sciences
Quinolones Medicine & Life Sciences
Parasites Medicine & Life Sciences
Qi Medicine & Life Sciences
4-Quinolones Medicine & Life Sciences
Atovaquone Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences

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Research Output 2008 2019

  • 386 Citations
  • 11 h-Index
  • 16 Article
  • 6 Chapter
  • 2 Review article
1 Citation (Scopus)

Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis

Hulverson, M. A., Bruzual, I., McConnell, E. V., Huang, W., Vidadala, R. S. R., Choi, R., Arnold, S. L. M., Whitman, G. R., McCloskey, M. C., Barrett, L. K., Rivas, K. L., Scheele, S., DeRocher, A. E., Parsons, M., Ojo, K. K., Maly, D. J., Fan, E., Van Voorhis, W. C. & Doggett, J., Apr 16 2019, In : The Journal of infectious diseases. 219, 9, p. 1464-1473 10 p.

Research output: Contribution to journalArticle

Open Access
Toxoplasmosis
Phosphotransferases
Pharmacokinetics
Toxoplasma
Poisons
11 Citations (Scopus)

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance

Kirkman, L. A., Zhan, W., Visone, J., Dziedziech, A., Singh, P. K., Fan, H., Tong, X., Bruzual, I., Hara, R., Kawasaki, M., Imaeda, T., Okamoto, R., Sato, K., Michino, M., Alvaro, E. F., Guiang, L. F., Sanz, L., Mota, D. J., Govindasamy, K., Wang, R. & 14 others, Ling, Y., Tumwebaze, P. K., Sukenick, G., Shi, L., Vendome, J., Bhanot, P., Rosenthal, P. J., Aso, K., Foley, M. A., Cooper, R. A., Kafsack, B., Doggett, J., Nathan, C. F. & Lin, G., Jul 17 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 29, p. E6863-E6870

Research output: Contribution to journalReview article

Open Access
ethylenediamine
Proteasome Inhibitors
Antimalarials
Plasmodium falciparum
Asparagine
2 Citations (Scopus)

BmGPAC, an antigen capture assay for detection of active babesia microti infection

Thekkiniath, J., Mootien, S., Lawres, L., Perrin, B. A., Gewirtz, M., Krause, P. J., Williams, S., Doggett, J., Ledizet, M. & Mamoun, C. B., Oct 1 2018, In : Journal of Clinical Microbiology. 56, 10, e00067.

Research output: Contribution to journalArticle

Babesia microti
Antigens
Infection
Babesiosis
Microscopy

Endochin-like quinolones exhibit promising efficacy against neospora caninum in vitro and in experimentally infected pregnant mice

Anghel, N., Balmer, V., Müller, J., Winzer, P., Aguado-Martinez, A., Roozbehani, M., Pou, S., Nilsen, A., Riscoe, M., Doggett, J. & Hemphill, A., Nov 19 2018, In : Frontiers in Veterinary Science. 5, NOV, 285.

Research output: Contribution to journalArticle

Neospora
quinolones
Neospora caninum
Quinolones
mice
5 Citations (Scopus)

Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis

McConnell, E. V., Bruzual, I., Pou, S., Winter, R., Dodean, R. A., Smilkstein, M. J., Krollenbrock, A., Nilsen, A., Zakharov, L. N., Riscoe, M. & Doggett, J., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

Qi
4-Quinolones
Electron Transport Complex III
Toxoplasmosis
Quinolones