Joseph Aslan

Assistant Professor

  • 1016 Citations
  • 16 h-Index
20052019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2019

ELMO1 deficiency enhances platelet function

Patel, A., Kostyak, J., Dangelmaier, C., Badolia, R., Bhavanasi, D., Aslan, J., Merali, S., Kim, S., Eble, J. A., Goldfinger, L. & Kunapuli, S., Feb 26 2019, In : Blood advances. 3, 4, p. 575-587 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Identification, Quantification, and System Analysis of Protein N-ε Lysine Methylation in Anucleate Blood Platelets

Rocheleau, A. D., Melrose, A. R., Cunliffe, J. M., Klimek, J., Babur, O., Tassi Yunga, S., Ngo, A. T. P., Pang, J., David, L., McCarty, O. & Aslan, J., Jan 1 2019, In : Proteomics. 1900001.

Research output: Contribution to journalArticle

Protease-activated receptor 4 activity promotes platelet granule release and platelet-leukocyte interactions

Rigg, R. A., Healy, L. D., Chu, T. T., Ngo, A. T. P., Mitrugno, A., Zilberman-Rudenko, J., Aslan, J. E., Hinds, M. T., Vecchiarelli, L. D., Morgan, T. K., Gruber, A., Temple, K. J., Lindsley, C. W., Duvernay, M. T., Hamm, H. E. & McCarty, O. J. T., Jan 2 2019, In : Platelets. 30, 1, p. 126-135 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Platelet procoagulant phenotype is modulated by a p38-MK2 axis that regulates RTN4/Nogo proximal to the endoplasmic reticulum: utility of pathway analysis

Babur, O., Ngo, A. T. P., Rigg, R. A., Pang, J., Rub, Z. T., Buchanan, A. E., Mitrugno, A., David, L., McCarty, O., Demir, E. & Aslan, J., May 1 2018, In : American journal of physiology. Cell physiology. 314, 5, p. C603-C615

Research output: Contribution to journalArticle

3 Scopus citations
2017

Assessment of roles for the rho-specific guanine nucleotide dissociation inhibitor Ly-GDI in platelet function: A spatial systems approach

Ngo, A. T. P., Thierheimer, M. L. D., Babur, O., Rocheleau, A. D., Huang, T., Pang, J., Rigg, R. A., Mitrugno, A., Theodorescu, D., Burchard, J., Nan, X., Demir, E., McCarty, O. & Aslan, J., Apr 7 2017, In : American Journal of Physiology - Cell Physiology. 312, 4, p. C527-C536

Research output: Contribution to journalArticle

7 Scopus citations

Potentiation of TRAP-6-induced platelet dense granule release by blockade of P2Y12 signaling with MRS2395

Mitrugno, A., Rigg, R. A., Laschober, N. B., Ngo, A. T. P., Pang, J., Williams, C. D., Aslan, J. & McCarty, O., May 20 2017, (Accepted/In press) In : Platelets. p. 1-12 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Heat shock protein 70 regulates platelet integrin activation, granule secretion and aggregation

Rigg, R. A., Healy, L. D., Nowak, M. S., Mallet, J., Thierheimer, M. L. D., Pang, J., McCarty, O. J. T. & Aslan, J. E., Apr 1 2016, In : American Journal of Physiology - Cell Physiology. 310, 7, p. C568-C575

Research output: Contribution to journalArticle

12 Scopus citations

Oral administration of Bruton's tyrosine kinase inhibitors impairs GPVI-mediated platelet function

Rigg, R. A., Aslan, J., Healy, L. D., Wallisch, M., Thierheimer, M. L. D., Loren, C. P., Pang, J., Hinds, M., Gruber, A. & McCarty, O., Mar 1 2016, In : American Journal of Physiology - Cell Physiology. 310, 5, p. C373-C380

Research output: Contribution to journalArticle

31 Scopus citations

PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage

Barroso-González, J., Auclair, S., Luan, S., Thomas, L., Atkins, K. M., Aslan, J., Thomas, L. L., Zhao, J., Zhao, Y. & Thomas, G., Mar 4 2016, (Accepted/In press) In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

16 Scopus citations
2015

Data detailing the platelet acetyl-lysine proteome

Aslan, J. E., David, L. L. & McCarty, O. J. T., Dec 1 2015, In : Data in Brief. 5, p. 368-371 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Lysine acetyltransfer supports platelet function

Aslan, J. E., Rigg, R. A., Nowak, M. S., Loren, C. P., Baker-Groberg, S. M., Pang, J., David, L. L. & Mccarty, O. J. T., Oct 1 2015, In : Journal of Thrombosis and Haemostasis. 13, 10, p. 1908-1917 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization

Kosoff, R. E., Aslan, J., Kostyak, J. C., Dulaimi, E., Chow, H. Y., Prudnikova, T. Y., Radu, M., Kunapuli, S. P., McCarty, O. & Chernoff, J., 2015, In : Blood. 125, 19, p. 2995-3005 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization

Kosoff, R. E., Aslan, J. E., Kostyak, J. C., Dulaimi, E., Chow, H. Y. E., Prudnikova, T. Y., Radu, M., Kunapuli, S. P., McCarty, O. J. T. & Chernoff, J., May 7 2015, In : Blood. 125, 19, p. 2995-3005 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
2013

A physical sciences network characterization of non-tumorigenic and metastatic cells

Agus, D. B., Alexander, J. F., Arap, W., Ashili, S., Aslan, J. E., Austin, R. H., Backman, V., Bethel, K. J., Bonneau, R., Chen, W. C., Chen-Tanyolac, C., Choi, N. C., Curley, S. A., Dallas, M., Damania, D., Davies, P. C. W., Decuzzi, P., Dickinson, L., Estevez-Salmeron, L., Estrella, V. & 75 others, Ferrari, M., Fischbach, C., Foo, J., Fraley, S. I., Frantz, C., Fuhrmann, A., Gascard, P., Gatenby, R. A., Geng, Y., Gerecht, S., Gillies, R. J., Godin, B., Grady, W. M., Greenfield, A., Hemphill, C., Hempstead, B. L., Hielscher, A., Hillis, W. D., Holland, E. C., Ibrahim-Hashim, A., Jacks, T., Johnson, R. H., Joo, A., Katz, J. E., Kelbauskas, L., Kesselman, C., King, M. R., Konstantopoulos, K., Kraning-Rush, C. M., Kuhn, P., Kung, K., Kwee, B., Lakins, J. N., Lambert, G., Liao, D., Licht, J. D., Liphardt, J. T., Liu, L., Lloyd, M. C., Lyubimova, A., Mallick, P., Marko, J., McCarty, O. J. T., Meldrum, D. R., Michor, F., Mumenthaler, S. M., Nandakumar, V., O'Halloran, T. V., Oh, S., Pasqualini, R., Paszek, M. J., Philips, K. G., Poultney, C. S., Rana, K., Reinhart-King, C. A., Ros, R., Semenza, G. L., Senechal, P., Shuler, M. L., Srinivasan, S., Staunton, J. R., Stypula, Y., Subramanian, H., Tlsty, T. D., Tormoen, G. W., Tseng, Y., Van Oudenaarden, A., Verbridge, S. S., Wan, J. C., Weaver, V. M., Widom, J., Will, C., Wirtz, D., Wojtkowiak, J. & Wu, P. H., Jul 4 2013, In : Scientific Reports. 3, 1449.

Research output: Contribution to journalArticle

91 Scopus citations

Histone deacetylase 6-mediated deacetylation of α-tubulin coordinates cytoskeletal and signaling events during platelet activation

Aslan, J. E., Phillips, K. G., Healy, L. D., Itakura, A., Pang, J. & McCarty, O. J. T., Dec 15 2013, In : American Journal of Physiology - Cell Physiology. 305, 12, p. C1230-C1239

Research output: Contribution to journalArticle

25 Scopus citations

p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils

Itakura, A., Aslan, J. E., Kusanto, B. T., Phillips, K. G., Porter, J. E., Newton, P. K., Nan, X., Insall, R. H., Chernoff, J. & McCarty, O. J. T., Sep 3 2013, In : PloS one. 8, 9, e73063.

Research output: Contribution to journalArticle

25 Scopus citations

P21 activated kinase signaling coordinates glycoprotein receptor VI-mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear

Aslan, J. E., Itakura, A., Haley, K. M., Tormoen, G. W., Loren, C. P., Baker, S. M., Pang, J., Chernoff, J. & McCarty, O. J. T., Jul 1 2013, In : Arteriosclerosis, thrombosis, and vascular biology. 33, 7, p. 1544-1551 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Rac and Cdc42 team up for platelets

Aslan, J. E. & McCarty, O. J. T., Oct 31 2013, In : Blood. 122, 18, p. 3096-3097 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation

Aslan, J. E., Baker, S. M., Loren, C. P., Haley, K. M., Itakura, A., Pang, J., Greenberg, D. L., David, L. L., Manser, E., Chernoff, J. & McCarty, O. J. T., Sep 1 2013, In : American Journal of Physiology - Cell Physiology. 305, 5, p. C519-C528

Research output: Contribution to journalArticle

25 Scopus citations
2012

Regulation of the mTOR-Rac1 axis in platelet function

Aslan, J. E. & McCarty, O. J. T., Jan 1 2012, In : Small GTPases. 3, 1

Research output: Contribution to journalArticle

12 Scopus citations
2011

Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

Aslan, J. E., Spencer, A. M., Loren, C. P., Pang, J., Welch, H. C., Greenberg, D. L. & McCarty, O. J. T., Sep 1 2011, In : Journal of Molecular Signaling. 6, 11.

Research output: Contribution to journalArticle

14 Scopus citations

Promotion of experimental thrombus formation by the procoagulant activity of breast cancer cells

Berny-Lang, M. A., Aslan, J. E., Tormoen, G. W., Patel, I. A., Bock, P. E., Gruber, A. & McCarty, O. J. T., Feb 2011, In : Physical Biology. 8, 1, 015014.

Research output: Contribution to journalArticle

18 Scopus citations

S6K1 and mTOR regulate Rac1-driven platelet activation and aggregation

Aslan, J. E., Tormoen, G. W., Loren, C. P., Pang, J. & McCarty, O. J. T., Sep 15 2011, In : Blood. 118, 11, p. 3129-3136 8 p.

Research output: Contribution to journalArticle

68 Scopus citations
2010

Characterization of human platelet binding of recombinant T cell receptor ligand

Itakura, A., Aslan, J. E., Sinha, S., White-Adams, T. C., Patel, I. A., Meza-Romero, R., Vandenbark, A. A., Burrows, G. G., Offner, H. & McCarty, O. J. T., Nov 8 2010, In : Journal of Neuroinflammation. 7, 75.

Research output: Contribution to journalArticle

15 Scopus citations
2009

Akt and 14-3-3 Control a PACS-2 Homeostatic Switch that Integrates Membrane Traffic with TRAIL-Induced Apoptosis

Aslan, J. E., You, H., Williamson, D. M., Endig, J., Youker, R. T., Thomas, L., Shu, H., Du, Y., Milewski, R. L., Brush, M. H., Possemato, A., Sprott, K., Fu, H., Greis, K. D., Runckel, D. N., Vogel, A. & Thomas, G., May 14 2009, In : Molecular Cell. 34, 4, p. 497-509 13 p.

Research output: Contribution to journalArticle

44 Scopus citations
2006

Sustained phosphorylation of Bid is a marker for resistance to fas-induced apoptosis during chronic liver diseases

Vogel, A., Aslan, J. E., Willenbring, H., Klein, C., Finegold, M., Mount, H., Thomas, G. & Grompe, M., Jan 2006, In : Gastroenterology. 130, 1, p. 104-119 16 p.

Research output: Contribution to journalArticle

26 Scopus citations
2005

PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis

Simmen, T., Aslan, J. E., Blagoveshchenskaya, A. D., Thomas, L., Wan, L., Xiang, Y., Feliciangeli, S. F., Hung, C. H., Crump, C. M. & Thomas, G., Feb 23 2005, In : EMBO Journal. 24, 4, p. 717-729 13 p.

Research output: Contribution to journalArticle

310 Scopus citations