John Jr Crabbe

Professor

  • 19760 Citations
  • 71 h-Index
1972 …2021

Research output per year

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Research Output

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Review article
2018

Reproducibility and replicability of rodent phenotyping in preclinical studies

Kafkafi, N., Agassi, J., Chesler, E. J., Crabbe, J. J., Crusio, W. E., Eilam, D., Gerlai, R., Golani, I., Gomez-Marin, A., Heller, R., Iraqi, F., Jaljuli, I., Karp, N. A., Morgan, H., Nicholson, G., Pfaff, D. W., Richter, S. H., Stark, P. B., Stiedl, O., Stodden, V. & 6 others, Tarantino, L. M., Tucci, V., Valdar, W., Williams, R. W., Würbel, H. & Benjamini, Y., Apr 1 2018, In : Neuroscience and Biobehavioral Reviews. 87, p. 218-232 15 p.

Research output: Contribution to journalReview article

28 Scopus citations
2015
15 Scopus citations
2014

High Drinking in the Dark Mice: A genetic model of drinking to intoxication

Barkley-Levenson, A. M. & Crabbe, J. C., May 2014, In : Alcohol. 48, 3, p. 217-223 7 p.

Research output: Contribution to journalReview article

22 Scopus citations
7 Scopus citations
2012

Translational behaviour-genetic studies of alcohol: Are we there yet?

Crabbe, J. C., Jun 1 2012, In : Genes, Brain and Behavior. 11, 4, p. 375-386 12 p.

Research output: Contribution to journalReview article

22 Scopus citations
2011

Bridging animal and human models: Translating from (and to) animal genetics

Barkley-Levenson, A. M. & Crabbe, J. C., Dec 1 2011, In : Alcohol Research and Health. 34, 3, p. 325-335 11 p.

Research output: Contribution to journalReview article

5 Scopus citations
2010

A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models

Ehlers, C. L., Walter, N. A. R., Dick, D. M., Buck, K. J. & Crabbe, J. C., Apr 1 2010, In : Addiction Biology. 15, 2, p. 185-199 15 p.

Research output: Contribution to journalReview article

46 Scopus citations

Acute withdrawal, protracted abstinence and negative affect in alcoholism: Are they linked?

Heilig, M., Egli, M., Crabbe, J. C. & Becker, H. C., Apr 1 2010, In : Addiction Biology. 15, 2, p. 169-184 16 p.

Research output: Contribution to journalReview article

243 Scopus citations

Consilient research approaches in studying gene × environment interactions in alcohol research

Sher, K. J., Dick, D. M., Crabbe, J. C., Hutchison, K. E., O'Malley, S. S. & Heath, A. C., Apr 1 2010, In : Addiction Biology. 15, 2, p. 200-216 17 p.

Research output: Contribution to journalReview article

30 Scopus citations

Human and laboratory rodent low response to alcohol: Is better consilience possible?

Crabbe, J. C., Bell, R. L. & Ehlers, C. L., Apr 1 2010, In : Addiction Biology. 15, 2, p. 125-144 20 p.

Research output: Contribution to journalReview article

55 Scopus citations

Reward sensitivity: Issues of measurement, and achieving consilience between human and animal phenotypes

Stephens, D. N., Duka, T., Crombag, H. S., Cunningham, C. L., Heilig, M. & Crabbe, J. C., Apr 1 2010, In : Addiction Biology. 15, 2, p. 146-168 23 p.

Research output: Contribution to journalReview article

67 Scopus citations
2008

Overview of mouse assays of ethanol intoxication

Crabbe, J. C., Cameron, A. J., Munn, E., Bunning, M. & Wahlsten, D., Jan 1 2008, In : Current Protocols in Neuroscience. SUPPL. 42, p. 9.26.1-9.26.19

Research output: Contribution to journalReview article

15 Scopus citations
2006

Alcohol-related genes: Contributions from studies with genetically engineered mice

Crabbe, J. C., Phillips, T. J., Harris, R. A., Arends, M. A. & Koob, G. F., Sep 1 2006, In : Addiction Biology. 11, 3-4, p. 195-269 75 p.

Research output: Contribution to journalReview article

175 Scopus citations
2005

An analysis of the genetics of alcohol intoxication in inbred mice

Crabbe, J. C., Metten, P., Cameron, A. J. & Wahlsten, D., Jan 1 2005, In : Neuroscience and Biobehavioral Reviews. 28, 8, p. 785-802 18 p.

Research output: Contribution to journalReview article

81 Scopus citations

Determining addiction - genes and substance use

Phillips, T. & Crabbe, J. J., Dec 1 2005, In : Drugs and Alcohol Today. 5, 4, p. 26-31 6 p.

Research output: Contribution to journalReview article

Gene expression induced by drugs of abuse

Rhodes, J. S. & Crabbe, J. C., Feb 1 2005, In : Current Opinion in Pharmacology. 5, 1, p. 26-33 8 p.

Research output: Contribution to journalReview article

40 Scopus citations

Laboratory models of alcoholism: Treatment target identification and insight into mechanisms

Lovinger, D. M. & Crabbe, J. C., Nov 1 2005, In : Nature Neuroscience. 8, 11, p. 1471-1480 10 p.

Research output: Contribution to journalReview article

79 Scopus citations
2004

Festina lente: Late-night thoughts on high-throughput screening of mouse behavior

Crabbe, J. C. & Morris, R. G. M., Nov 1 2004, In : Nature Neuroscience. 7, 11, p. 1175-1179 5 p.

Research output: Contribution to journalReview article

58 Scopus citations

Pharmacogenetic studies of alcohol self-administration and withdrawal

Crabbe, J. C. & Phillips, T. J., Aug 2004, In : Psychopharmacology. 174, 4, p. 539-560 22 p.

Research output: Contribution to journalReview article

27 Scopus citations

The Collaborative Cross, a community resource for the genetic analysis of complex traits

Churchill, G. A., Airey, D. C., Allayee, H., Angel, J. M., Attie, A. D., Beatty, J., Beavis, W. D., Belknap, J. K., Bennett, B., Berrettini, W., Bleich, A., Bogue, M., Broman, K. W., Buck, K. J., Buckler, E., Burmeister, M., Chesler, E. J., Cheverud, J. M., Clapcote, S., Cook, M. N. & 93 others, Cox, R. D., Crabbe, J. C., Crusio, W. E., Darvasi, A., Deschepper, C. F., Doerge, R. W., Farber, C. R., Forejt, J., Gaile, D., Garlow, S. J., Geiger, H., Gershenfeld, H., Gordon, T., Gu, J., Gu, W., de Haan, G., Hayes, N. L., Heller, C., Himmelbauer, H., Hitzemann, R., Hunter, K., Hsu, H. C., Iraqi, F. A., Ivandic, B., Jacob, H. J., Jansen, R. C., Jepsen, K. J., Johnson, D. K., Johnson, T. E., Kempermann, G., Kendziorski, C., Kotb, M., Kooy, R. F., Llamas, B., Lammert, F., Lassalle, J. M., Lowenstein, P. R., Lu, L., Lusis, A., Manly, K. F., Marcucio, R., Matthews, D., Medrano, J. F., Miller, D. R., Mittleman, G., Mock, B. A., Mogil, J. S., Montagutelli, X., Morahan, G., Morris, D. G., Mott, R., Nadeau, J. H., Nagase, H., Nowakowski, R. S., O'Hara, B. F., Osadchuk, A. V., Page, G. P., Paigen, B., Paigen, K., Palmer, A. A., Pan, H. J., Peltonen-Palotie, L., Peirce, J., Pomp, D., Pravenec, M., Prows, D. R., Qi, Z., Reeves, R. H., Roder, J., Rosen, G. D., Schadt, E. E., Schalkwyk, L. C., Seltzer, Z., Shimomura, K., Shou, S., Sillanpää, M. J., Siracusa, L. D., Snoeck, H. W., Spearow, J. L., Svenson, K., Tarantino, L. M., Threadgill, D., Toth, L. A., Valdar, W., Pardo-Manuel de Villena, F., Warden, C., Whatley, S., Williams, R. W., Wiltshire, T., Yi, N., Zhang, D., Zhang, M. & Zou, F., Nov 2004, In : Nature genetics. 36, 11, p. 1133-1137 5 p.

Research output: Contribution to journalReview article

676 Scopus citations
75 Scopus citations

Veterans Administration support for medical research: Opinions of the endangered species of physician-scientists

Zucker, S., Crabbe, J. C., Cooper IV, G., Finkelman, F., Largman, C., Mccarley, R. W., Rice, L., Rubin, J., Richardson, B., Seil, F., Snider, G. L. & Vandenbark, A. A., Oct 1 2004, In : FASEB Journal. 18, 13, p. 1481-1486 6 p.

Research output: Contribution to journalReview article

8 Scopus citations
2003

Different data from different labs: Lessons from studies of gene-environment interaction

Wahlsten, D., Metten, P., Phillips, T. J., Boehm, S. L., Burkhart-Kasch, S., Dorow, J., Doerksen, S., Downing, C., Fogarty, J., Rodd-Henricks, K., Hen, R., McKinnon, C. S., Merrill, C. M., Nolte, C., Schalomon, M., Schlumbohm, J. P., Sibert, J. R., Wenger, C. D., Dudek, B. C. & Crabbe, J. C., Jan 1 2003, In : Journal of Neurobiology. 54, 1, p. 283-311 29 p.

Research output: Contribution to journalReview article

342 Scopus citations

Genetic animal models of anxiety

Finn, D. A., Rutledge-Gorman, M. T. & Crabbe, J. C., Apr 1 2003, In : Neurogenetics. 4, 3, p. 109-135 27 p.

Research output: Contribution to journalReview article

125 Scopus citations

In search of a better mouse test

Wahlsten, D., Rustay, N. R., Metten, P. & Crabbe, J. C., Mar 1 2003, In : Trends in Neurosciences. 26, 3, p. 132-136 5 p.

Research output: Contribution to journalReview article

118 Scopus citations

Progress towards finding genes for alcoholism in mice

Rhodes, J. S. & Crabbe, J. C., Dec 1 2003, In : Clinical Neuroscience Research. 3, 4-5, p. 315-323 9 p.

Research output: Contribution to journalReview article

5 Scopus citations

The nature and identification of quantitative trait loci: A community's view

Abiola, O., Angel, J. M., Avner, P., Bachmanov, A. A., Belknap, J. K., Bennett, B., Blankenhorn, E. P., Blizard, D. A., Bolivar, V., Brockmann, G. A., Buck, K. J., Bureau, J. F., Casley, W. L., Chesler, E. J., Cheverud, J. M., Churchill, G. A., Cook, M., Crabbe, J. C., Crusio, W. E., Darvasi, A. & 60 others, de Haan, G., Demant, P., Doerge, R. W., Elliott, R. W., Farber, C. R., Flaherty, L., Flint, J., Gershenfeld, H., Gibson, J. P., Gu, J., Gu, W., Himmelbauer, H., Hitzemann, R., Hsu, H. C., Hunter, K., Iraqi, F. A., Jansen, R. C., Johnson, T. E., Jones, B. C., Kempermann, G., Lammert, F., Lu, L., Manly, K. F., Matthews, D. B., Medrano, J. F., Mehrabian, M., Mittleman, G., Mock, B. A., Mogil, J. S., Montagutelli, X., Morahan, G., Mountz, J. D., Nagase, H., Nowakowski, R. S., O'Hara, B. F., Osadchuk, A. V., Paigen, B., Palmer, A. A., Peirce, J. L., Pomp, D., Rosemann, M., Rosen, G. D., Schalkwyk, L. C., Seltzer, Z., Settle, S., Shimomura, K., Shou, S., Sikela, J. M., Siracusa, L. D., Spearow, J. L., Teuscher, C., Threadgill, D. W., Toth, L. A., Toye, A. A., Vadasz, C., Van Zant, G., Wakeland, E., Williams, R. W., Zhang, H. G. & Zou, F., Nov 1 2003, In : Nature Reviews Genetics. 4, 11, p. 911-916 6 p.

Research output: Contribution to journalReview article

299 Scopus citations
2002

Future of genetics of mood disorders research

Merikangas, K. R., Chakravarti, A., Moldin, S. O., Araj, H., Blangero, J., Burmeister, M., Crabbe, J. C., Depaulo, J. R., Foulks, E., Freimer, N. B., Koretz, D. S., Lichtenstein, W., Mignot, E., Reiss, A. L., Risch, N. J. & Takahashi, J. S., Sep 15 2002, In : Biological Psychiatry. 52, 6, p. 457-477 21 p.

Research output: Contribution to journalReview article

109 Scopus citations

Harnessing the mouse to unravel the genetics of human disease

Phillips, T. J., Belknap, J. K., Hitzemann, R. J., Buck, K. J., Cunningham, C. L. & Crabbe, J. C., Jan 1 2002, In : Genes, Brain and Behavior. 1, 1, p. 14-26 13 p.

Research output: Contribution to journalReview article

63 Scopus citations
2001

QTL analysis and genomewide mutagenesis in mice: Complementary genetic approaches to the dissection of complex traits

Belknap, J. K., Hitzemann, R., Crabbe, J. C., Phillips, T. J., Buck, K. J. & Williams, R. W., Aug 31 2001, In : Behavior genetics. 31, 1, p. 5-15 11 p.

Research output: Contribution to journalReview article

71 Scopus citations

Use of genetic analyses to refine phenotypes related to alcohol tolerance and dependence

Crabbe, J. C., Jan 1 2001, In : Alcoholism: Clinical and Experimental Research. 25, 2, p. 288-292 5 p.

Research output: Contribution to journalReview article

28 Scopus citations
1999

Alcohol and genetics: New animal models

Browman, K. E. & Crabbe, J. C., Jul 1 1999, In : Molecular Medicine Today. 5, 7, p. 310-318 9 p.

Research output: Contribution to journalReview article

16 Scopus citations

Identifying genes for alcohol and drug sensitivity: Recent progress and future directions

Crabbe, J. C., Phillips, T. J., Buck, K. J., Cunningham, C. L. & Belknap, J. K., Apr 1 1999, In : Trends in Neurosciences. 22, 4, p. 173-179 7 p.

Research output: Contribution to journalReview article

213 Scopus citations
1997

Behavioral phenotypes of inbred mouse strains: Implications and recommendations for molecular studies

Crawley, J. N., Belknap, J. K., Collins, A., Crabbe, J. C., Frankel, W., Henderson, N., Hitzemann, R. J., Maxson, S. C., Miner, L. L., Silva, A. J., Wehner, J. M., Wynshaw-Boris, A. & Paylor, R., Aug 25 1997, In : Psychopharmacology. 132, 2, p. 107-124 18 p.

Research output: Contribution to journalReview article

1136 Scopus citations
1996

Quantitative trait locus gene mapping: A new method for locating alcohol response genes

Crabbe, J. C., Jan 1 1996, In : Addiction Biology. 1, 3, p. 229-235 7 p.

Research output: Contribution to journalReview article

6 Scopus citations

Strategies for identifying genes underlying drug abuse susceptibility.

Crabbe, J. C., Buck, K. J., Metten, P. & Belknap, J. K., 1996, In : NIDA research monograph. 161, p. 201-219 19 p.

Research output: Contribution to journalReview article

5 Scopus citations
1994

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

Crabbe, J. C., Belknap, J. K., Buck, K. J. & Metten, P., 1994, In : Alcohol and alcoholism (Oxford, Oxfordshire). Supplement.. 2, p. 67-71 5 p.

Research output: Contribution to journalReview article

29 Scopus citations
1993

Behavior genetic analyses of drug withdrawal.

Crabbe, J. C. & Belknap, J. K., 1993, In : Alcohol and alcoholism (Oxford, Oxfordshire). Supplement.. 2, p. 477-482 6 p.

Research output: Contribution to journalReview article

12 Scopus citations
1991

Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology

Gora-Maslak, G., McClearn, G. E., Crabbe, J. C., Phillips, T. J., Belknap, J. K. & Plomin, R., Aug 1 1991, In : Psychopharmacology. 104, 4, p. 413-424 12 p.

Research output: Contribution to journalReview article

158 Scopus citations
1989

Selected mouse lines, alcohol and behavior

Phillips, T. J., Feller, D. J. & Crabbe, J. C., Sep 1 1989, In : Experientia. 45, 9, p. 805-827 23 p.

Research output: Contribution to journalReview article

72 Scopus citations
1980

Pharmacogenetic tools in the study of drug tolerance and dependence

Crabbe, J. C. & Belknap, J. K., Dec 1 1980, In : Substance and Alcohol Actions/Misuse. 1, 5-6, p. 385-413 29 p.

Research output: Contribution to journalReview article

39 Scopus citations