• 67731 Citations
  • 113 h-Index
1971 …2020

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Subregional localization of 21 chromosome 7-specific expressed sequence tags (ESTs) by FISH using newly identified YACs and P1s

Morton, S. M., Veile, R. A., Helms, C., Lee, M., Kuo, W. L., Gray, J. & Donis-Keller, H., Dec 15 1997, In : Genomics. 46, 3, p. 491-494 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Subtype and pathway specific responses to anticancer compounds in breast cancer

Heiser, L. M., Sadanandam, A., Kuo, W. L., Benz, S. C., Goldstein, T. C., Ng, S., Gibb, W. J., Wang, N. J., Ziyad, S., Tong, F., Bayani, N., Hu, Z., Billig, J. I., Dueregger, A., Lewis, S., Jakkula, L., Korkola, J. E., Durinck, S., Pepin, F., Guan, Y. & 23 others, Purdom, E., Neuvial, P., Bengtsson, H., Wood, K. W., Smith, P. G., Vassilev, L. T., Hennessy, B. T., Greshock, J., Bachman, K. E., Hardwicke, M. A., Park, J. W., Marton, L. J., Wolf, D. M., Collisson, E. A., Neve, R. M., Mills, G. B., Speed, T. P., Feiler, H. S., Richard, F. W., Haussler, D., Stuart, J. M., Gray, J. W. & Spellman, P. T., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 2724-2729 6 p.

Research output: Contribution to journalArticle

275 Scopus citations

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

Collisson, E. A., Sadanandam, A., Olson, P., Gibb, W. J., Truitt, M., Gu, S., Cooc, J., Weinkle, J., Kim, G. E., Jakkula, L., Feiler, H. S., Ko, A. H., Olshen, A. B., Danenberg, K. L., Tempero, M. A., Spellman, P. T., Hanahan, D. & Gray, J. W., Apr 2011, In : Nature medicine. 17, 4, p. 500-503 4 p.

Research output: Contribution to journalArticle

627 Scopus citations

Synthesis of Y chromosome-specific labeled DNA probes by in vitro DNA amplification

Weier, H. U. G., Segraves, R., Pinkel, D. & Gray, J. W., Jan 1 1990, In : Journal of Histochemistry and Cytochemistry. 38, 3, p. 421-426 6 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Systems biology in cancer research: genomics to cellomics.

Stilwell, J. L., Guan, Y., Neve, R. M. & Gray, J. W., 2007, In : Methods in molecular biology (Clifton, N.J.). 356, p. 353-365 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Targeted treatment of metastatic breast cancer by PLK1 siRNA delivered by an antioxidant nanoparticle platform

Morry, J., Ngamcherdtrakul, W., Gu, S., Reda, M., Castro, D. J., Sangvanich, T., Gray, J. W. & Yantasee, W., Apr 2017, In : Molecular cancer therapeutics. 16, 4, p. 763-772 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Targeting mitochondria in cancer therapy could provide a basis for the selective anticancer activity

Rozanov, D., Cheltsov, A., Nilsen, A., Boniface, C., Forquer, I., Korkola, J., Gray, J., Tyner, J., Tognon, C. E., Mills, G. B. & Spellman, P., Mar 2019, In : PloS one. 14, 3, e0205623.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Targeting the mevalonate pathway to overcome acquired anti-HER2 treatment resistance in breast cancer

Sethunath, V., Hu, H., De Angelis, C., Veeraraghavan, J., Qin, L., Wang, N., Simon, L. M., Wang, T., Fu, X., Nardone, A., Pereira, R., Nanda, S., Griffith, O. L., Tsimelzon, A., Shaw, C., Chamness, G. C., Reis-Filho, J. S., Weigelt, B., Heiser, L. M., Hilsenbeck, S. G. & 5 others, Huang, S., Rimawi, M. F., Gray, J. W., Osborne, C. K. & Schiff, R., 2019, In : Molecular Cancer Research. 17, 11, p. 2318-2330 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Targeting uPAR with antagonistic recombinant human antibodies in aggressive breast cancer

Le Beau, A. M., Duriseti, S., Murphy, S. T., Pepin, F., Hann, B., Gray, J. W., Van Brocklin, H. F. & Craik, C. S., Apr 1 2013, In : Cancer Research. 73, 7, p. 2070-2081 12 p.

Research output: Contribution to journalArticle

45 Scopus citations

TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines

Fan, W., Huang, X., Chen, C., Gray, J. & Huang, T., Aug 1 2004, In : Cancer Research. 64, 15, p. 5132-5139 8 p.

Research output: Contribution to journalArticle

89 Scopus citations

Technical approaches for efficient, high precision nucleic acid analysis using DNA microarrays

Pinkel, D., Hamilton, G., Brown, N., Segraves, R., Huey, B., Snijders, A., Blackwood, S., Hindle, K., Law, S., Gray, J., Jain, A., Hanson, J., Nordmeyer, R. & Albertson, D., Jan 1 2002, In : Proceedings of SPIE-The International Society for Optical Engineering. 4626, p. 82-88 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Temporal dissection of tumorigenesis in primary cancers

Durinck, S., Ho, C., Wang, N., Liao, W., Jakkula, L. R., Collisson, E. A., Pons, J., Chan, S. W., Lam, E. T., Chu, C., Park, K., Hong, S. W., Hur, J. S., Huh, N., Neuhaus, I. M., Yu, S. S., Grekin, R. C., Mauro, T. M., Cleaver, J. E., Kwok, P. Y. & 12 others, LeBoit, P. E., Getz, G., Cibulskis, K., Aster, J. C., Huang, H., Purdom, E., Li, J., Bolund, L., Arron, S. T., Gray, J. W., Spellman, P. T. & Cho, R. J., Jun 29 2011, In : Cancer discovery. 1, 2, p. 137-143 7 p.

Research output: Contribution to journalArticle

152 Scopus citations

The analysis and interpretation of DNA distributions measured by flow cytometry

Dean, P. N., Gray, J. W. & Dolbeare, F. A., Nov 1982, In : Cytometry. 3, 3, p. 188-195 8 p.

Research output: Contribution to journalArticle

81 Scopus citations

The binding kinetics and interaction of DNA fluorochromes used in the analysis of nuclei and chromosomes by flow cytometry

van den Engh, G. J., Trask, B. J. & Gray, J. W., Jul 1 1986, In : Histochemistry. 84, 4-6, p. 501-508 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

The consensus molecular subtypes of colorectal cancer

Guinney, J., Dienstmann, R., Wang, X., De Reyniès, A., Schlicker, A., Soneson, C., Marisa, L., Roepman, P., Nyamundanda, G., Angelino, P., Bot, B. M., Morris, J. S., Simon, I. M., Gerster, S., Fessler, E., De Sousa .E Melo, F., Missiaglia, E., Ramay, H., Barras, D., Homicsko, K. & 20 others, Maru, D., Manyam, G. C., Broom, B., Boige, V., Perez-Villamil, B., Laderas, T., Salazar, R., Gray, J. W., Hanahan, D., Tabernero, J., Bernards, R., Friend, S. H., Laurent-Puig, P., Medema, J. P., Sadanandam, A., Wessels, L., Delorenzi, M., Kopetz, S., Vermeulen, L. & Tejpar, S., Nov 1 2015, In : Nature medicine. 21, 11, p. 1350-1356 7 p.

Research output: Contribution to journalArticle

1338 Scopus citations

The distribution of nuclear DNA from human brain-tumor cells. Flow cytometric studies

Hoshino, T., Nomura, K., Wilson, C. B., Knebel, K. D. & Gray, J. W., Jan 1 1978, In : Unknown Journal. 49, 1, p. 13-21 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment

Turpin, J., Ling, C., Crosby, E. J., Hartman, Z. C., Simond, A. M., Chodosh, L. A., Rennhack, J. P., Andrechek, E. R., Ozcelik, J., Hallett, M., Mills, G. B., Cardiff, R. D., Gray, J. W., Griffith, O. L. & Muller, W. J., Nov 24 2016, In : Oncogene. 35, 47, p. 6053-6064 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas

Sun, Y., Wong, N., Guan, Y., Salamanca, C. M., Jung, C. C., Lee, J. M., Gray, J. W. & Auersperg, N., Oct 15 2008, In : International Journal of Cancer. 123, 8, p. 1761-1769 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer

Hu, Z., Huang, G., Sadanandam, A., Gu, S., Lenburg, M. E., Pai, M., Bayani, N., Blakely, E. A., Gray, J. W. & Mao, J. H., Mar 8 2010, In : Breast Cancer Research. 12, 2, R18.

Research output: Contribution to journalArticle

75 Scopus citations

The LLNL high‐speed sorter: Design features, operational characteristics, and biological utility

Peters, D., Branscomb, E., Dean, P., Merrill, T., Pinkel, D., Van Dilla, M. & Gray, J. W., Jul 1985, In : Cytometry. 6, 4, p. 290-301 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

Gupta, P. B., Kuperwasser, C., Brunet, J. P., Ramaswamy, S., Kuo, W. L., Gray, J. W., Naber, S. P. & Weinberg, R. A., Oct 1 2005, In : Nature genetics. 37, 10, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

326 Scopus citations

The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression

Kenny, P. A., Lee, G. Y., Myers, C. A., Neve, R. M., Semeiks, J. R., Spellman, P. T., Lorenz, K., Lee, E. H., Barcellos-Hoff, M. H., Petersen, O. W., Gray, J. W. & Bissell, M. J., Jun 2007, In : Molecular Oncology. 1, 1, p. 84-96 13 p.

Research output: Contribution to journalArticle

621 Scopus citations

The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

Cheng, K. W., Lahad, J. P., Kuo, W. L., Lapuk, A., Yamada, K., Auersperg, N., Liu, J., Smith-McCune, K., Lu, K. H., Fishman, D., Gray, J. W. & Mills, G. B., Nov 1 2004, In : Nature medicine. 10, 11, p. 1251-1256 6 p.

Research output: Contribution to journalArticle

379 Scopus citations

Therapeutic siRNA for drug-resistant HER2-positive breast cancer

Gu, S., Hu, Z., Ngamcherdtrakul, W., Castro, D. J., Morry, J., Reda, M. M., Gray, J. W. & Yantasee, W., Mar 22 2016, In : Oncotarget. 7, 12, p. 14727-14741 15 p.

Research output: Contribution to journalArticle

15 Scopus citations
1 Scopus citations

The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy

Mills, G. B., Lu, Y., Fang, X., Wang, H., Eder, A., Mao, M., Swaby, R., Cheng, K. W., Stokoe, D., Siminovitch, K., Jaffe, R. & Gray, J., Jan 1 2001, In : Seminars in Oncology. 28, 5 SUPPL. 16, p. 125-141 17 p.

Research output: Contribution to journalArticle

112 Scopus citations

The Role of p53 in Suppression of KSHV Cyclin-induced Lymphomagenesis

Verschuren, E. W., Hodgson, J. G., Gray, J. W., Kogan, S., Jones, N. & Evan, G. I., Jan 15 2004, In : Cancer Research. 64, 2, p. 581-589 9 p.

Research output: Contribution to journalArticle

68 Scopus citations

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

Sternlicht, M. D., Lochtest, A., Sympson, C. J., Huey, B., Rougier, J. P., Gray, J. W., Pinkel, D., Bissell, M. J. & Werb, Z., Jul 23 1999, In : Cell. 98, 2, p. 137-146 10 p.

Research output: Contribution to journalArticle

713 Scopus citations

The transcription factor ZNF217 Is a prognostic biomarker and therapeutic target during breast cancer progression

Littlepage, L. E., Adler, A. S., Kouros-Mehr, H., Huang, G., Chou, J., Krig, S. R., Griffi th, O. L., Korkola, J. E., Qu, K., Lawson, D. A., Xue, Q., Sternlicht, M. D., Dijkgraaf, G. J. P., Yaswen, P., Rugo, H. S., Sweeney, C. A., Collins, C. C., Gray, J. W., Chang, H. Y. & Werb, Z., Jul 2012, In : Cancer discovery. 2, 7, p. 638-651 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells

Nonet, G. H., Stampfer, M. R., Chin, K., Gray, J. W., Collins, C. C. & Yaswen, P., Feb 15 2001, In : Cancer Research. 61, 4, p. 1250-1254 5 p.

Research output: Contribution to journalArticle

121 Scopus citations

Thick-section fluorescence in situ hybridization on formalin-fixed, paraffin-embedded archival tissue provides a histogenetic profile

Thompson, C. T., LeBoit, P. E., Nederlof, P. M. & Gray, J. W., Feb 1 1994, In : American Journal of Pathology. 144, 2, p. 237-243 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

Three-dimensional analysis of the organization of human chromosome domains in human and human-hamster hybrid interphase nuclei

Van Dekken, H., Pinkel, D., Mullikin, J., Trask, B., Van Den Engh, G. & Gray, J., Jan 1 1989, In : Journal of Cell Science. 94, 2, p. 299-306 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Three dimensional reconstruction of human chromosomes in hybrid and human cell line nuclei using fluorescence in situ hybridization.

van Dekken, H., Pinkel, D., Mullikin, J., Trask, B., van den Engh, G. & Gray, J., 1989, In : Acta histochemica. Supplementband. 37, p. 91-94 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Topographic enhancement mapping of the cancer-associated breast stroma using breast MRI

Nabavizadeh, N., Klifa, C., Newitt, D., Lu, Y., Chen, Y. Y., Hsu, H., Fisher, C., Tokayasu, T., Olshen, A. B., Spellman, P., Gray, J. W., Hylton, N. & Park, C. C., Apr 1 2011, In : Integrative Biology. 3, 4, p. 490-496 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution

Cheng, J. B., Sedgewick, A. J., Finnegan, A. I., Harirchian, P., Lee, J., Kwon, S., Fassett, M. S., Golovato, J., Gray, M., Ghadially, R., Liao, W., Perez White, B. E., Mauro, T. M., Mully, T., Kim, E. A., Sbitany, H., Neuhaus, I. M., Grekin, R. C., Yu, S. S., Gray, J. W. & 6 others, Purdom, E., Paus, R., Vaske, C. J., Benz, S. C., Song, J. S. & Cho, R. J., Oct 23 2018, In : Cell Reports. 25, 4, p. 871-883 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Transcription Restores DNA Repair to Heterochromatin, Determining Regional Mutation Rates in Cancer Genomes

Zheng, C. L., Wang, N. J., Chung, J., Moslehi, H., Sanborn, J. Z., Hur, J. S., Collisson, E. A., Vemula, S. S., Naujokas, A., Chiotti, K. E., Cheng, J. B., Fassihi, H., Blumberg, A. J., Bailey, C. V., Fudem, G. M., Mihm, F. G., Cunningham, B. B., Neuhaus, I. M., Liao, W., Oh, D. H. & 10 others, Cleaver, J. E., LeBoit, P. E., Costello, J. F., Lehmann, A. R., Gray, J. W., Spellman, P. T., Arron, S. T., Huh, N., Purdom, E. & Cho, R. J., Nov 20 2014, In : Cell Reports. 9, 4, p. 1228-1234 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Translating laboratory knowledge into biological therapy and genetic analysis

Gray, J., Jan 1 2003, In : Breast Journal. 9, SUPPL. 1, p. S29-S31

Research output: Contribution to journalArticle

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

Zhou, H., Kuang, J., Zhong, L., Kuo, W. L., Gray, J. W., Sahin, A., Brinkley, B. R. & Sen, S., Oct 15 1998, In : Nature genetics. 20, 2, p. 189-193 5 p.

Research output: Contribution to journalArticle

1082 Scopus citations

Two-color hybridization with high complexity chromosome-specific probes and a degenerate alpha satellite probe DNA allows unambiguous discrimination between symmetrical and asymmetrical translocations

Weier, H. U. G., Lucas, J. N., Poggensee, M., Segraves, R., Pinkel, D. & Gray, J. W., Jul 1 1991, In : Chromosoma. 100, 6, p. 371-376 6 p.

Research output: Contribution to journalArticle

74 Scopus citations

Upregulation of ER signaling as an adaptive mechanism of cell survival in HER2-positive breast tumors treated with Anti-HER2 therapy

Giuliano, M., Hu, H., Wang, Y. C., Fu, X., Nardone, A., Herrera, S., Mao, S., Contreras, A., Gutierrez, C., Wang, T., Hilsenbeck, S. G., Angelis, C. D., Wang, N. J., Heiser, L. M., Gray, J. W., Lopez-Tarruella, S., Pavlick, A. C., Trivedi, M. V., Chamness, G. C., Chang, J. C. & 3 others, Osborne, C. K., Rimawi, M. F. & Schiff, R., Sep 1 2015, In : Clinical Cancer Research. 21, 17, p. 3995-4003 9 p.

Research output: Contribution to journalArticle

43 Scopus citations

Use of restriction endonucleases and exonuclease III to expose halogenated pyrimidines for immunochemical staining

Dolbeare, F. & Gray, J. W., Nov 1988, In : Cytometry. 9, 6, p. 631-635 5 p.

Research output: Contribution to journalArticle

40 Scopus citations

Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors

Petrillo, L. A., Wolf, D. M., Kapoun, A. M., Wang, N. J., Barczak, A., Xiao, Y., Korkaya, H., Baehner, F., Lewicki, J., Wicha, M., Park, J. W., Spellman, P. T., Gray, J. W., Van'T Veer, L. & Esserman, L. J., Oct 1 2012, In : Breast Cancer Research and Treatment. 135, 3, p. 913-922 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

X-ray laser microscopy of rat sperm nuclei

Da Silva, L. B., Trebes, J. E., Balhorn, R., Mrowka, S., Anderson, E., Attwood, D. T., Barbee, T. W., Brase, J., Corzett, M., Gray, J., Koch, J. A., Lee, C., Kern, D., London, R. A., MacGowan, B. J., Matthews, D. L. & Stone, G., Jan 1 1992, In : Science. 258, 5080, p. 269-271 3 p.

Research output: Contribution to journalArticle

128 Scopus citations

Yin Yang 1 modulates taxane response in epithelial ovarian cancer

Matsumura, N., Huang, Z., Baba, T., Lee, P. S., Barnett, J. C., Mori, S., Chang, J. T., Kuo, W. L., Gusberg, A. H., Whitaker, R. S., Gray, J. W., Fujii, S., Berchuck, A. & Murphy, S. K., Feb 1 2009, In : Molecular Cancer Research. 7, 2, p. 210-220 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

β1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo

Park, C. C., Zhang, H., Pallavicini, M., Gray, J. W., Baehner, F., Park, C. J. & Bissell, M. J., Feb 1 2006, In : Cancer Research. 66, 3, p. 1526-1535 10 p.

Research output: Contribution to journalArticle

253 Scopus citations