• 67731 Citations
  • 113 h-Index
1971 …2020

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Article
2012

Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: Results from the I-SPY 1 TRIAL - CALGB 150007/150012, ACRIN 6657

Esserman, L. J., Berry, D. A., DeMichele, A., Carey, L., Davis, S. E., Buxton, M., Hudis, C., Gray, J. W., Perou, C., Yau, C., Livasy, C., Krontiras, H., Montgomery, L., Tripathy, D., Lehman, C., Liu, M. C., Olopade, O. I., Rugo, H. S., Carpenter, J. T., Dressler, L. & 8 others, Chhieng, D., Singh, B., Mies, C., Rabban, J., Chen, Y. Y., Giri, D., Van't Veer, L. & Hylton, N., Sep 10 2012, In : Journal of Clinical Oncology. 30, 26, p. 3242-3249 8 p.

Research output: Contribution to journalArticle

262 Scopus citations

Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress

Cheng, K. W., Agarwal, R., Mitra, S., Lee, J. S., Carey, M., Gray, J. W. & Mills, G. B., Feb 1 2012, In : EMBO Molecular Medicine. 4, 2, p. 125-141 17 p.

Research output: Contribution to journalArticle

48 Scopus citations

Subtype and pathway specific responses to anticancer compounds in breast cancer

Heiser, L. M., Sadanandam, A., Kuo, W. L., Benz, S. C., Goldstein, T. C., Ng, S., Gibb, W. J., Wang, N. J., Ziyad, S., Tong, F., Bayani, N., Hu, Z., Billig, J. I., Dueregger, A., Lewis, S., Jakkula, L., Korkola, J. E., Durinck, S., Pepin, F., Guan, Y. & 23 others, Purdom, E., Neuvial, P., Bengtsson, H., Wood, K. W., Smith, P. G., Vassilev, L. T., Hennessy, B. T., Greshock, J., Bachman, K. E., Hardwicke, M. A., Park, J. W., Marton, L. J., Wolf, D. M., Collisson, E. A., Neve, R. M., Mills, G. B., Speed, T. P., Feiler, H. S., Richard, F. W., Haussler, D., Stuart, J. M., Gray, J. W. & Spellman, P. T., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 2724-2729 6 p.

Research output: Contribution to journalArticle

275 Scopus citations

The transcription factor ZNF217 Is a prognostic biomarker and therapeutic target during breast cancer progression

Littlepage, L. E., Adler, A. S., Kouros-Mehr, H., Huang, G., Chou, J., Krig, S. R., Griffi th, O. L., Korkola, J. E., Qu, K., Lawson, D. A., Xue, Q., Sternlicht, M. D., Dijkgraaf, G. J. P., Yaswen, P., Rugo, H. S., Sweeney, C. A., Collins, C. C., Gray, J. W., Chang, H. Y. & Werb, Z., Jul 2012, In : Cancer discovery. 2, 7, p. 638-651 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors

Petrillo, L. A., Wolf, D. M., Kapoun, A. M., Wang, N. J., Barczak, A., Xiao, Y., Korkaya, H., Baehner, F., Lewicki, J., Wicha, M., Park, J. W., Spellman, P. T., Gray, J. W., Van'T Veer, L. & Esserman, L. J., Oct 1 2012, In : Breast Cancer Research and Treatment. 135, 3, p. 913-922 10 p.

Research output: Contribution to journalArticle

28 Scopus citations
2013

A colorectal cancer classification system that associates cellular phenotype and responses to therapy

Sadanandam, A., Lyssiotis, C. A., Homicsko, K., Collisson, E. A., Gibb, W. J., Wullschleger, S., Ostos, L. C. G., Lannon, W. A., Grotzinger, C., Del Rio, M., Lhermitte, B., Olshen, A. B., Wiedenmann, B., Cantley, L. C., Gray, J. W. & Hanahan, D., May 2013, In : Nature medicine. 19, 5, p. 619-625 7 p.

Research output: Contribution to journalArticle

512 Scopus citations

A robust prognostic signature for hormone-positive node-negative breast cancer

Griffith, O. L., Pepin, F., Enache, O. M., Heiser, L. M., Collisson, E. A., Spellman, P. T. & Gray, J. W., Oct 11 2013, In : Genome Medicine. 5, 10, 92.

Research output: Contribution to journalArticle

11 Scopus citations

CpG island shore methylation regulates caveolin-1 expression in breast cancer

Rao, X., Evans, J., Chae, H., Pilrose, J., Kim, S., Yan, P., Huang, R. L., Lai, H. C., Lin, H., Liu, Y., Miller, D., Rhee, J. K., Huang, Y. W., Gu, F., Gray, J. W., Huang, T. M. & Nephew, K. P., Sep 19 2013, In : Oncogene. 32, 38, p. 4519-4528 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

C-Src modulates estrogen-induced stress and apoptosis in estrogen-deprived breast cancer cells

Fan, P., Griffith, O. L., Agboke, F. A., Anur, P., Zou, X., McDaniel, R. E., Creswell, K., Kim, S. H., Katzenellenbogen, J. A., Gray, J. W. & Jordan, V. C., Jul 15 2013, In : Cancer Research. 73, 14, p. 4510-4520 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target

Timmerman, L. A., Holton, T., Yuneva, M., Louie, R. J., Padró, M., Daemen, A., Hu, M., Chan, D. A., Ethier, S. P., van'tVeer, L. J., Polyak, K., McCormick, F. & Gray, J. W., Oct 14 2013, In : Cancer Cell. 24, 4, p. 450-465 16 p.

Research output: Contribution to journalArticle

228 Scopus citations

Identification and quantification of AKT isoforms and phosphoforms in breast cancer using a novel nanofluidic immunoassay

Iacovides, D. C., Johnson, A. B., Wang, N., Boddapati, S., Korkola, J. & Gray, J. W., Nov 1 2013, In : Molecular and Cellular Proteomics. 12, 11, p. 3210-3220 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer

Rhee, J. K., Kim, K., Chae, H., Evans, J., Yan, P., Zhang, B. T., Gray, J., Spellman, P., Huang, T. H. M., Nephew, K. P. & Kim, S., Oct 2013, In : Nucleic acids research. 41, 18, p. 8464-8474 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association

Chang, H., Han, J., Borowsky, A., Loss, L., Gray, J. W., Spellman, P. T. & Parvin, B., Apr 15 2013, In : IEEE Transactions on Medical Imaging. 32, 4, p. 670-682 13 p., 6374258.

Research output: Contribution to journalArticle

65 Scopus citations

Metrics other than potency reveal systematic variation in responses to cancer drugs

Fallahi-Sichani, M., Honarnejad, S., Heiser, L. M., Gray, J. W. & Sorger, P. K., Nov 1 2013, In : Nature Chemical Biology. 9, 11, p. 708-714 7 p.

Research output: Contribution to journalArticle

159 Scopus citations

Modeling precision treatment of breast cancer

Daemen, A., Griffith, O. L., Heiser, L. M., Wang, N. J., Enache, O. M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J. E., Griffith, M., Hur, J. S., Huh, N., Chung, J., Cope, L., Fackler, M. J., Umbricht, C., Sukumar, S., Seth, P., Sukhatme, V. P., Jakkula, L. R. & 7 others, Lu, Y., Mills, G. B., Cho, R. J., Collisson, E. A., van't Veer, L. J., Spellman, P. T. & Gray, J. W., Dec 10 2013, In : Genome biology. 14, 10, R110.

Research output: Contribution to journalArticle

Open Access
141 Scopus citations

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

Verhaak, R. G. W., Tamayo, P., Yang, J. Y., Hubbard, D., Zhang, H., Creighton, C. J., Fereday, S., Lawrence, M., Carter, S. L., Mermel, C. H., Kostic, A. D., Etemadmoghadam, D., Saksena, G., Cibulskis, K., Duraisamy, S., Levanon, K., Sougnez, C., Tsherniak, A., Gomez, S., Onofrio, R. & 21 others, Gabriel, S., Chin, L., Zhang, N., Spellman, P. T., Zhang, Y., Akbani, R., Hoadley, K. A., Kahn, A., Köbel, M., Huntsman, D., Soslow, R. A., Defazio, A., Birrer, M. J., Gray, J. W., Weinstein, J. N., Bowtell, D. D., Drapkin, R., Mesirov, J. P., Getz, G., Levine, D. A. & Meyerson, M., Jan 2 2013, In : Journal of Clinical Investigation. 123, 1, p. 517-525 9 p.

Research output: Contribution to journalArticle

297 Scopus citations

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Lovci, M. T., Ghanem, D., Marr, H., Arnold, J., Gee, S., Parra, M., Liang, T. Y., Stark, T. J., Gehman, L. T., Hoon, S., Massirer, K. B., Pratt, G. A., Black, D. L., Gray, J. W., Conboy, J. G. & Yeo, G. W., Dec 1 2013, In : Nature Structural and Molecular Biology. 20, 12, p. 1434-1442 9 p.

Research output: Contribution to journalArticle

134 Scopus citations

Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling

Nan, X., Collisson, E. A., Lewis, S., Huang, J., Tamgüney, T. M., Liphardt, J. T., McCormick, F., Gray, J. W. & Chu, S., Nov 12 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 46, p. 18519-18524 6 p.

Research output: Contribution to journalArticle

91 Scopus citations

Targeting uPAR with antagonistic recombinant human antibodies in aggressive breast cancer

Le Beau, A. M., Duriseti, S., Murphy, S. T., Pepin, F., Hann, B., Gray, J. W., Van Brocklin, H. F. & Craik, C. S., Apr 1 2013, In : Cancer Research. 73, 7, p. 2070-2081 12 p.

Research output: Contribution to journalArticle

45 Scopus citations
2014

A community computational challenge to predict the activity of pairs of compounds

Cellworks Group & NCI DREAM Community, Dec 1 2014, In : Nature biotechnology. 32, 12, p. 1213-1222 10 p.

Research output: Contribution to journalArticle

122 Scopus citations

A community effort to assess and improve drug sensitivity prediction algorithms

NCI DREAM Community, Dec 1 2014, In : Nature biotechnology. 32, 12, p. 1202-1212 11 p.

Research output: Contribution to journalArticle

290 Scopus citations

Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells

Zhang, H., Fan, Y., Ge, N., Wang, X., Sun, W., Mao, R., Bu, W., Creighton, C. J., Zheng, P., Vasudevan, S., An, L., Yang, J., Zhao, Y. J., Zhang, H., Li, X. N., Rao, P. H., Leung, E., Lu, Y. J., Gray, J. W., Schiff, R. & 3 others, Hilsenbeck, S. G., Osborne, C. K. & Yang, J., Jan 2014, In : Journal of Pathology. 232, 1, p. 75-86 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Causal network inference using biochemical kinetics

Oates, C. J., Dondelinger, F., Bayani, N., Korkola, J., Gray, J. W. & Mukherjee, S., Sep 1 2014, In : Bioinformatics. 30, 17, p. i468-i474

Research output: Contribution to journalArticle

32 Scopus citations

Copy Number Gain of hsa-miR-569 at 3q26.2 Leads to Loss of TP53INP1 and Aggressiveness of Epithelial Cancers

Chaluvally-Raghavan, P., Zhang, F., Pradeep, S., Hamilton, M. P., Zhao, X., Rupaimoole, R., Moss, T., Lu, Y., Yu, S., Pecot, C. V., Aure, M. R., Peuget, S., Rodriguez-Aguayo, C., Han, H. D., Zhang, D., Venkatanarayan, A., Krohn, M., Kristensen, V. N., Gagea, M., Ram, P. & 11 others, Liu, W., Lopez-Berestein, G., Lorenzi, P. L., Børresen-Dale, A. L., Chin, K., Gray, J., Dusetti, N. J., McGuire, S. E., Flores, E. R., Sood, A. K. & Mills, G. B., Dec 8 2014, In : Cancer Cell. 26, 6, p. 863-879 17 p.

Research output: Contribution to journalArticle

31 Scopus citations

CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression

Wang, Y., Wen, M., Kwon, Y., Xu, Y., Liu, Y., Zhang, P., He, X., Wang, Q., Huang, Y., Jen, K. Y., Labarge, M. A., You, L., Kogan, S. C., Gray, J. W., Mao, J. H. & Wei, G., Jan 15 2014, In : Cancer Research. 74, 2, p. 520-531 12 p.

Research output: Contribution to journalArticle

142 Scopus citations

Do breast cancer cell lines provide a relevant model of the patient tumor methylome?

Cope, L. M., Fackler, M. J., Lopez-Bujanda, Z., Wolff, A. C., Visvanathan, K., Gray, J. W., Sukumar, S. & Umbricht, C. B., Aug 26 2014, In : PloS one. 9, 8, e105545.

Research output: Contribution to journalArticle

10 Scopus citations

Endocytic trafficking of laminin is controlled by dystroglycan and is disrupted in cancers

Leonoudakis, D., Huang, G., Akhavan, A., Fata, J. E., Singh, M., Gray, J. W. & Muschler, J. L., Jan 1 2014, In : Journal of Cell Science. 127, 22, p. 4894-4903 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Exact reconstruction of gene regulatory networks using compressive sensing

Chang, Y. H., Gray, J. W. & Tomlin, C. J., Dec 14 2014, In : BMC bioinformatics. 15, 1, 400.

Research output: Contribution to journalArticle

22 Scopus citations

Identification of gene regulation patterns underlying both oestrogen- and tamoxifen-stimulated cell growth through global gene expression profiling in breast cancer cells

Fan, P., Cunliffe, H. E., Griffith, O. L., Agboke, F. A., Ramos, P., Gray, J. W. & Jordan, V. C., Nov 2014, In : European Journal of Cancer. 50, 16, p. 2877-2886 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Joint estimation of multiple related biological networks

Oates, C. J., Korkola, J., Gray, J. W. & Mukherjee, S., Sep 1 2014, In : Annals of Applied Statistics. 8, 3, p. 1892-1919 28 p.

Research output: Contribution to journalArticle

12 Scopus citations

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase

Fu, X., Creighton, C. J., Biswal, N. C., Kumar, V., Shea, M., Herrera, S., Contreras, A., Gutierrez, C., Wang, T., Nanda, S., Giuliano, M., Morrison, G., Nardone, A., Karlin, K. L., Westbrook, T. F., Heiser, L. M., Anur, P., Spellman, P., Guichard, S. M., Smith, P. D. & 10 others, Davies, B. R., Klinowska, T., Lee, A. V., Mills, G. B., Rimawi, M. F., Hilsenbeck, S. G., Gray, J. W., Joshi, A., Osborne, C. K. & Schiff, R., Sep 11 2014, In : Breast Cancer Research. 16, 5, 430.

Research output: Contribution to journalArticle

47 Scopus citations

Reconciliation of classification systems defining molecular subtypes of colorectal cancer: Interrelationships and clinical implications

Sadanandam, A., Wang, X., De Sousa E Melo, F., Gray, J. W., Vermeulen, L., Hanahan, D. & Medema, J. P., Feb 1 2014, In : Cell Cycle. 13, 3, p. 353-357 5 p.

Research output: Contribution to journalArticle

51 Scopus citations

Transcription Restores DNA Repair to Heterochromatin, Determining Regional Mutation Rates in Cancer Genomes

Zheng, C. L., Wang, N. J., Chung, J., Moslehi, H., Sanborn, J. Z., Hur, J. S., Collisson, E. A., Vemula, S. S., Naujokas, A., Chiotti, K. E., Cheng, J. B., Fassihi, H., Blumberg, A. J., Bailey, C. V., Fudem, G. M., Mihm, F. G., Cunningham, B. B., Neuhaus, I. M., Liao, W., Oh, D. H. & 10 others, Cleaver, J. E., LeBoit, P. E., Costello, J. F., Lehmann, A. R., Gray, J. W., Spellman, P. T., Arron, S. T., Huh, N., Purdom, E. & Cho, R. J., Nov 20 2014, In : Cell Reports. 9, 4, p. 1228-1234 7 p.

Research output: Contribution to journalArticle

50 Scopus citations
2015

Cationic polymer modified mesoporous silica nanoparticles for targeted siRNA delivery to HER2+ breast cancer

Ngamcherdtrakul, W., Morry, J., Gu, S., Castro, D. J., Goodyear, S. M., Sangvanich, T., Reda, M. M., Lee, R., Mihelic, S. A., Beckman, B. L., Hu, Z., Gray, J. W. & Yantasee, W., May 13 2015, In : Advanced Functional Materials. 25, 18, p. 2646-2659 14 p.

Research output: Contribution to journalArticle

101 Scopus citations

Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer

Korkola, J. E., Collisson, E. A., Heiser, L., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N. J., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Feiler, H., Lu, Y., Mills, G. B., Spellman, P. T., Tomlin, C. & 3 others, Mukherjee, S., Gray, J. W. & Jakkula, L., Jul 16 2015, In : PloS one. 10, 7, e0133219.

Research output: Contribution to journalArticle

11 Scopus citations

Disentangling multidimensional spatio-temporal data into their common and aberrant responses

Chang, Y. H., Korkola, J., Amin, D. N., Moasser, M. M., Carmena, J. M., Gray, J. W. & Tomlin, C. J., Apr 22 2015, In : PloS one. 10, 4, e0121607.

Research output: Contribution to journalArticle

1 Scopus citations

Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease

Butler, T. M., Johnson-Camacho, K., Peto, M., Wang, N. J., Macey, T. A., Korkola, J. E., Koppie, T. M., Corless, C. L., Gray, J. W. & Spellman, P. T., Aug 28 2015, In : PloS one. 10, 8, e0136407.

Research output: Contribution to journalArticle

65 Scopus citations

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

Shain, A. H., Garrido, M., Botton, T., Talevich, E., Yeh, I., Sanborn, J. Z., Chung, J., Wang, N. J., Kakavand, H., Mann, G. J., Thompson, J. F., Wiesner, T., Roy, R., Olshen, A. B., Gagnon, A., Gray, J. W., Huh, N., Hur, J. S., Busam, K. J., Scolyer, R. A. & 3 others, Cho, R. J., Murali, R. & Bastian, B. C., Sep 29 2015, In : Nature genetics. 47, 10, p. 1194-1199 6 p.

Research output: Contribution to journalArticle

108 Scopus citations

Genome-wide perturbations by miRNAs map onto functional cellular pathways, identifying regulators of chromatin modifiers

Moss, T. J., Luo, Z., Seviour, E. G., Sehgal, V., Lu, Y., Hill, S. M., Rupaimoole, R., Lee, J. S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Sood, A. K., Azencott, R., Gray, J., Mukherjee, S., Mills, G. & Ram, P. T., Sep 28 2015, In : npj Systems Biology and Applications. 1, 15001.

Research output: Contribution to journalArticle

2 Scopus citations

Large-scale drug screens support precision medicine

Gray, J. W. & Mills, G. B., Nov 2015, In : Cancer discovery. 5, 11, p. 1130-1132 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination

Sanborn, J. Z., Chung, J., Purdom, E., Wang, N. J., Kakavand, H., Wilmott, J. S., Butler, T., Thompson, J. F., Mann, G. J., Haydu, L. E., Saw, R. P. M., Busam, K. J., Lo, R. S., Collisson, E. A., Hur, J. S., Spellman, P. T., Cleaver, J. E., Gray, J. W., Huh, N., Murali, R. & 3 others, Scolyer, R. A., Bastian, B. C. & Cho, R. J., Sep 1 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 35, p. 10995-11000 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway

Nan, X., Tamgüney, T. M., Collisson, E. A., Lin, L. J., Pitt, C., Galeas, J., Lewis, S., Gray, J. W., McCormick, F. & Chu, S., Jun 30 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 26, p. 7996-8001 6 p.

Research output: Contribution to journalArticle

122 Scopus citations

The consensus molecular subtypes of colorectal cancer

Guinney, J., Dienstmann, R., Wang, X., De Reyniès, A., Schlicker, A., Soneson, C., Marisa, L., Roepman, P., Nyamundanda, G., Angelino, P., Bot, B. M., Morris, J. S., Simon, I. M., Gerster, S., Fessler, E., De Sousa .E Melo, F., Missiaglia, E., Ramay, H., Barras, D., Homicsko, K. & 20 others, Maru, D., Manyam, G. C., Broom, B., Boige, V., Perez-Villamil, B., Laderas, T., Salazar, R., Gray, J. W., Hanahan, D., Tabernero, J., Bernards, R., Friend, S. H., Laurent-Puig, P., Medema, J. P., Sadanandam, A., Wessels, L., Delorenzi, M., Kopetz, S., Vermeulen, L. & Tejpar, S., Nov 1 2015, In : Nature medicine. 21, 11, p. 1350-1356 7 p.

Research output: Contribution to journalArticle

1338 Scopus citations

Upregulation of ER signaling as an adaptive mechanism of cell survival in HER2-positive breast tumors treated with Anti-HER2 therapy

Giuliano, M., Hu, H., Wang, Y. C., Fu, X., Nardone, A., Herrera, S., Mao, S., Contreras, A., Gutierrez, C., Wang, T., Hilsenbeck, S. G., Angelis, C. D., Wang, N. J., Heiser, L. M., Gray, J. W., Lopez-Tarruella, S., Pavlick, A. C., Trivedi, M. V., Chamness, G. C., Chang, J. C. & 3 others, Osborne, C. K., Rimawi, M. F. & Schiff, R., Sep 1 2015, In : Clinical Cancer Research. 21, 17, p. 3995-4003 9 p.

Research output: Contribution to journalArticle

43 Scopus citations
2016

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

Bruna, A., Rueda, O. M., Greenwood, W., Batra, A. S., Callari, M., Batra, R. N., Pogrebniak, K., Sandoval, J., Cassidy, J. W., Tufegdzic-Vidakovic, A., Sammut, S. J., Jones, L., Provenzano, E., Baird, R., Eirew, P., Hadfield, J., Eldridge, M., McLaren-Douglas, A., Barthorpe, A., Lightfoot, H. & 10 others, O'Connor, M. J., Gray, J., Cortes, J., Baselga, J., Marangoni, E., Welm, A. L., Aparicio, S., Serra, V., Garnett, M. J. & Caldas, C., Sep 22 2016, In : Cell. 167, 1, p. 260-274.e22

Research output: Contribution to journalArticle

150 Scopus citations

ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin

Fleyshman, D., Cheney, P., Ströse, A., Mudambi, S., Safina, A., Commane, M., Purmal, A., Morgan, K., Wang, N. J., Gray, J., Spellman, P., Issaeva, N. & Gurova, K., Feb 1 2016, In : Cell Cycle. 15, 3, p. 455-470 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

Current development of targeted oligonucleotide-based cancer therapies: Perspective on HER2-positive breast cancer treatment

Ngamcherdtrakul, W., Castro, D. J., Gu, S., Morry, J., Reda, M., Gray, J. & Yantasee, W., Apr 1 2016, In : Cancer Treatment Reviews. 45, p. 19-29 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

Fu, X., Jeselsohn, R., Pereira, R., Hollingsworth, E. F., Creighton, C. J., Li, F., Shea, M., Nardone, A., De Angelis, C., Heiser, L. M., Anur, P., Wang, N., Grasso, C. S., Spellman, P. T., Griffith, O. L., Tsimelzon, A., Gutierrez, C., Huang, S., Edwards, D. P., Trivedi, M. V. & 7 others, Rimawi, M. F., Lopez-Terrada, D., Hilsenbeck, S. G., Gray, J. W., Brown, M., Osborne, C. K. & Schiff, R., Oct 25 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 43, p. E6600-E6609

Research output: Contribution to journalArticle

47 Scopus citations

Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death

Guest, S. T., Kratche, Z. R., Irish, J. C., Wilson, R. C., Haddad, R., Gray, J. W., Garrett-Mayer, E. & Ethier, S. P., 2016, In : Oncotarget. 7, 24, p. 36138-36153 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer

Seviour, E. G., Sehgal, V., Lu, Y., Luo, Z., Moss, T., Zhang, F., Hill, S. M., Liu, W., Maiti, S. N., Cooper, L., Azencot, R., Lopez-Berestein, G., Rodriguez-Aguayo, C., Roopaimoole, R., Pecot, C., Sood, A. K., Mukherjee, S., Gray, J. W., Mills, G. B. & Ram, P. T., Feb 11 2016, In : Oncogene. 35, 6, p. 691-701 11 p.

Research output: Contribution to journalArticle

26 Scopus citations