• 67302 Citations
  • 113 h-Index
1971 …2020

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1992

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

Kallioniemi, A., Kallioniemi, O. P., Sudar, D., Rutovitz, D., Gray, J. W., Waldman, F. & Pinkel, D., Jan 1 1992, In : Science. 258, 5083, p. 818-821 4 p.

Research output: Contribution to journalArticle

2750 Scopus citations

Construction and characterization of a yeast artificial chromosome library containing 1.5 equivalents of human chromosome 21

Potier, M. C., Kuo, W. L., Dutriaux, A., Gray, J. & Goedert, M., Oct 1992, In : Genomics. 14, 2, p. 481-483 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

Deletion of Chromosome 17p Loci in Breast Cancer Cells Detected by Fluorescence in Situ Hybridization

Matsumura, K., Kallioniemi, A., Kallioniemi, O., Chen, L., Smith, H. S., Pinkel, D., Gray, J. & Waldman, F. M., Jun 1992, In : Cancer Research. 52, 12, p. 3474-3477 4 p.

Research output: Contribution to journalArticle

107 Scopus citations

Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization

Kallioniemi, A., Kallioniemi, O. P., Waidman, F. M., Chen, L. C., Yu, L. C., Fung, Y. K. T., Smith, H. S., Pinkel, D. & Gray, J. W., Jan 1 1992, In : Cytogenetic and Genome Research. 60, 3-4, p. 190-193 4 p.

Research output: Contribution to journalArticle

45 Scopus citations

Differential staining of human and murine chromatin in situ by hybridization with species-specific satellite DNA probes

Weier, H. U. G., Zitzelsberger, H. F. & Gray, J. W., Feb 14 1992, In : Biochemical and Biophysical Research Communications. 182, 3, p. 1313-1319 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization

Kallioniemi, O. P., Kallioniemi, A., Kurisu, W., Thor, A., Chen, L. C., Smith, H. S., Waldman, F. M., Pinkel, D. & Gray, J. W., Jun 22 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 12, p. 5321-5325 5 p.

Research output: Contribution to journalArticle

Open Access
443 Scopus citations

Factors that Determine the in vivo Dose-Response Relationship for Stable Chromosome Aberrations in A-Bomb Survivors

Awa, A. A., Nakano, M., Ohtaki, K., Kodama, Y., Lucas, J. & Gray, J., Jan 1 1992, In : Journal of radiation research. 33, p. 206-214 9 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Molecular cytogenetics: Diagnosis and prognostic assessment

Gray, J. W., Kallioniemi, A., Kallioniemi, O., Pallavicini, M., Waldman, F. & Pinkel, D., Dec 1992, In : Current Opinion in Biotechnology. 3, 6, p. 623-631 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Molecular cytogenetics in human cancer diagnosis

Gray, J. W. & Pinkel, D., Mar 15 1992, In : Cancer. 69, 6 S, p. 1536-1542 7 p.

Research output: Contribution to journalArticle

67 Scopus citations

Radiation-induced chromosome aberrations analysed by fluorescence in situ hybridization with a triple combination of composite whole chromosome-specific DNA probes

Schmid, E., Zitzelsberger, H., Braselmann, H., Gray, J. W. & Bauchinger, M., Jan 1 1992, In : International Journal of Radiation Biology. 62, 6, p. 673-678 6 p.

Research output: Contribution to journalArticle

131 Scopus citations

Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation

Lucas, J. N., Awa, A., Straume, T., Poggensee, M., Kodama, Y., Nakano, M., Ohtaki, K., Weier, H. U., Pinkel, D., Gray, J. & Littlefield, G., Jan 1 1992, In : International Journal of Radiation Biology. 62, 1, p. 53-63 11 p.

Research output: Contribution to journalArticle

426 Scopus citations

Structural Chromosome Analysis by Whole Chromosome Painting for Assessment of Radiation-Induced Genetic Damage

Gray, J. W., Pinkel, D., Lucas, J. N. & Awa, A., Jan 1 1992, In : Journal of radiation research. 33, p. 80-86 7 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

X-ray laser microscopy of rat sperm nuclei

Da Silva, L. B., Trebes, J. E., Balhorn, R., Mrowka, S., Anderson, E., Attwood, D. T., Barbee, T. W., Brase, J., Corzett, M., Gray, J., Koch, J. A., Lee, C., Kern, D., London, R. A., MacGowan, B. J., Matthews, D. L. & Stone, G., Jan 1 1992, In : Science. 258, 5080, p. 269-271 3 p.

Research output: Contribution to journalArticle

128 Scopus citations
1991

Characterization of somatic cell hybrids by bivariate flow karyotyping and fluorescence in situ hybridization

Trask, B. J., van den Engh, G., Christensen, M., Massa, H. F., Gray, J. W. & Van Dilla, M., Mar 1 1991, In : Somatic Cell and Molecular Genetics. 17, 2, p. 117-136 20 p.

Research output: Contribution to journalArticle

38 Scopus citations

Clinical applications of fluorescence in situ hybridization

Tkachuk, D. C., Pinkel, D., Kuo, W. L., Weier, H. U. & Gray, J. W., Apr 1991, In : Genetic Analysis: Biomolecular Engineering. 8, 2, p. 67-74 8 p.

Research output: Contribution to journalArticle

81 Scopus citations

Construction and characterization of plasmid libraries enriched in sequences from single human chromosomes

Collins, C., Kuo, W. L., Segraves, R., Fuscoe, J., Pinkel, D. & Gray, J. W., Dec 1991, In : Genomics. 11, 4, p. 997-1006 10 p.

Research output: Contribution to journalArticle

213 Scopus citations

Detection of aneuploidy involving chromosomes 13, 18, or 21, by fluorescence in situ hybridization (FISH) to interphase and metaphase amniocytes

Kuo, W. L., Tenijn, H., Segraves, R., Pinkel, D., Golbus, M. S. & Gray, J., Aug 29 1991, In : American Journal of Human Genetics. 49, 1, p. 112-119 8 p.

Research output: Contribution to journalArticle

113 Scopus citations

Dicentric chromosome frequency analysis using slit‐scan flow cytometry

Lucas, J. N., Mullikin, J. C. & Gray, J. W., 1991, In : Cytometry. 12, 4, p. 316-322 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Labeling of the centromeric region on human chromosome 8 by in situ hybridization

Weier, H. U. G., Gray, J. W. & Kleine, H. D., Aug 1 1991, In : Human genetics. 87, 4, p. 489-494 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Non-isotopical labeling of murine heterochromatin in situ by hybridization with in vitro-synthesized biotinylated gamma (major) satellite DNA

Weier, H. U., Zitzelsberger, H. F. & Gray, J. W., Jun 28 1991, In : BioTechniques. 10, 4, p. 498-502+504-505

Research output: Contribution to journalArticle

39 Scopus citations

Observations regarding DNA replication sites in human cells in vivo following infusions of iododeoxyuridine and bromodeoxyuridine

Raza, A., Miller, M. A., Mazewski, C., Sheikh, Y., Lampkin, B., Sawaya, R., Crone, K., Berger, T., Reising, J., Gray, J., Khan, S. & Preisler, H., Mar 1991, In : Cell Proliferation. 24, 2, p. 113-126 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Two-color hybridization with high complexity chromosome-specific probes and a degenerate alpha satellite probe DNA allows unambiguous discrimination between symmetrical and asymmetrical translocations

Weier, H. U. G., Lucas, J. N., Poggensee, M., Segraves, R., Pinkel, D. & Gray, J. W., Jul 1 1991, In : Chromosoma. 100, 6, p. 371-376 6 p.

Research output: Contribution to journalArticle

74 Scopus citations
1990

Analytical approaches to detection and characterization of disease-linked chromosome aberrations

Gray, J. W., Kuo, W. L., Liang, J., Pinkel, D., Van den Engh Trask, G. B., Tkachuk, D., Waldman, F. & Westbrook, C., Jan 1 1990, In : Bone marrow transplantation. 6, SUPPL. 1, p. 14-19 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Automated detection of chromosome aberration using color information

Chen, C. H., Wang, Y., Mitra, S. K. & Gray, J., Mar 1 1990, In : Proceedings of SPIE - The International Society for Optical Engineering. 1192, p. 339-343 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine

Asai, A., Shibui, S., Barker, M., Vanderlaan, M., Gray, J. W. & Hoshino, T., Jan 1 1990, In : Journal of neurosurgery. 73, 2, p. 254-258 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Chapter 21 Using Monoclonal Antibodies in Bromodeoxyuridine—DNA Analysis

Dolbeare, F., Kuo, W. L., Beisker, W., Vanderlaan, M. & Gray, J. W., Jan 1 1990, In : Methods in cell biology. 33, C, p. 207-216 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Characterization and organization of DNA sequences adjacent to the human telomere associated repeat (TTAGGG)n

Weber, B., Collins, C., Robbins, C., Magenis, R. E., Delaney, A. D., Gray, J. W. & Hayden, M. R., Jun 11 1990, In : Nucleic acids research. 18, 11, p. 3353-3361 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization

Tkachuk, D. C., Westbrook, C. A., Andreeff, M., Donlon, T. A., Cleary, M. L., Suryanarayan, K., Homge, M., Redner, A., Gray, J. & Pinkel, D., Jan 1 1990, In : Science. 250, 4980, p. 559-562 4 p.

Research output: Contribution to journalArticle

333 Scopus citations

Effects of methotrexate on transfected DNA stability in mammalian cells

Pallavicini, M. G., Deteresa, P. S., Rosette, C., Gray, J. W. & Wurm, F. M., Jan 1990, In : Molecular and cellular biology. 10, 1, p. 401-404 4 p.

Research output: Contribution to journalArticle

Open Access
76 Scopus citations

Quantification of the DNA content of structurally abnormal X chromosomes and X chromosome aneuploidy using high resolution bivariate flow karyotyping

Trask, B., van den Engh, G., Nussbaum, R., Schwartz, C. & Gray, J., 1990, In : Cytometry. 11, 1, p. 184-195 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Relationship of c‐myc gene copy number and gene expression: Cellular effects of elevated c‐myc protein

Pallavicini, M. G., Rosette, C., Reitsma, M., Deteresa, P. S. & Gray, J. W., May 1990, In : Journal of Cellular Physiology. 143, 2, p. 372-380 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Synthesis of Y chromosome-specific labeled DNA probes by in vitro DNA amplification

Weier, H. U. G., Segraves, R., Pinkel, D. & Gray, J. W., Jan 1 1990, In : Journal of Histochemistry and Cytochemistry. 38, 3, p. 421-426 6 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations
1989

An efficient method for selecting unique-sequence clones from DNA libraries and its application to fluorescent staining of human chromosome 21 using in situ hybridization

Fuscoe, J. C., Collins, C. C., Pinkel, D. & Gray, J. W., Jul 1989, In : Genomics. 5, 1, p. 100-109 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Chromosome heteromorphism quantified by high-resolution bivariate flow karyotyping

Trask, B., Van den Engh, G., Mayall, B. & Gray, J. W., Jan 1 1989, In : American Journal of Human Genetics. 45, 5, p. 739-752 14 p.

Research output: Contribution to journalArticle

57 Scopus citations

Double labeling with iodo- and bromodeoxyuridine for cell kinetic studies

Shibui, S., Hoshino, T., Vanderlaan, M. & Gray, J. W., Jan 1 1989, In : Journal of Histochemistry and Cytochemistry. 37, 7, p. 1007-1011 5 p.

Research output: Contribution to journalArticle

Open Access
72 Scopus citations

Fluorescent nucleic add hybridization methods

Pinkel, D., Gray, J., Segraves, R., Waldman, F., Trask, B., Yu, L. C., Eastmond, D. & Dean, P., Jun 13 1989, In : Proceedings of SPIE - The International Society for Optical Engineering. 1063, p. 123-132 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Inheritance of chromosome heteromorphisms analyzed by high-resolution bivariate flow karyotyping

Trask, B., Van den Engh, G. & Gray, J. W., Jan 1 1989, In : American Journal of Human Genetics. 45, 5, p. 753-760 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Rapid human chromosome aberration analysis using fluorescence in situ hybridization

Lucas, J. N., Tenjin, T., Straume, T., Pinkel, D., Moore, D., Litt, M. & Gray, J. W., Jan 1 1989, In : International Journal of Radiation Biology. 56, 1, p. 35-44 10 p.

Research output: Contribution to journalArticle

174 Scopus citations

Three-dimensional analysis of the organization of human chromosome domains in human and human-hamster hybrid interphase nuclei

Van Dekken, H., Pinkel, D., Mullikin, J., Trask, B., Van Den Engh, G. & Gray, J., Jan 1 1989, In : Journal of Cell Science. 94, 2, p. 299-306 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Three dimensional reconstruction of human chromosomes in hybrid and human cell line nuclei using fluorescence in situ hybridization.

van Dekken, H., Pinkel, D., Mullikin, J., Trask, B., van den Engh, G. & Gray, J., 1989, In : Acta histochemica. Supplementband. 37, p. 91-94 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
1988

Application of flow karyotyping in prenatal detection of chromosome aberrations

Gray, J. W., Trask, B., Van Den Engh, G., Silva, A., Lozes, C., Schonberg, S., Yu, L. C. & Golbus, M. S., Jan 1 1988, In : American Journal of Human Genetics. 42, 1, p. 49-59 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

A Programmable System to Perform the Polymerase Chain Reaction

Weier, H. U. & Gray, J. W., Jul 1988, In : DNA. 7, 6, p. 441-447 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Clinical applications of the bromodeoxyuridine/DNA assay

Waldman, F. M., Dolbeare, F. & Gray, J., 1988, In : Cytometry. 9, 3 S, p. 65-72 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Enzymatic production of single-stranded DNA as a target for fluorescence in situ hybridization

van Dekken, H., Pinkel, D., Mullikin, J. & Gray, J. W., Sep 1 1988, In : Chromosoma. 97, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Fluorescence in situ hybridization to interphase cell nuclei in suspension allows flow cytometric analysis of chromosome content and microscopic analysis of nuclear organization

Trask, B., van den Engh, G., Pinkel, D., Mullikin, J., Waldman, F., van Dekken, H. & Gray, J., Mar 1 1988, In : Human genetics. 78, 3, p. 251-259 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Fluorescence in situ hybridization with human chromosome-specific libraries: Detection of trisomy 21 and translocations of chromosome 4

Pinkel, D., Landegent, J., Collins, C., Fuscoe, J., Segraves, R., Lucas, J. & Gray, J., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 23, p. 9138-9142 5 p.

Research output: Contribution to journalArticle

Open Access
1138 Scopus citations

Fringe‐scan flow cytometry

Mullikin, J., Norgren, R., Lucas, J. & Gray, J., Mar 1988, In : Cytometry. 9, 2, p. 111-120 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Improved resolution of flow cytometric measurements of hoechst‐ and chromomycin‐A3‐stained human chromosomes after addition of citrate and sulfite

Engh, G. V. D., Trask, B., Gray, J. & Lansdorp, P., May 1988, In : Cytometry. 9, 3, p. 266-270 5 p.

Research output: Contribution to journalArticle

48 Scopus citations

Prenatal detection of 46,XY,rec(5),dup q, inv(5)(p13q33) using DNA analysis, flow cytometry, and in situ hybridization to supplement classical cytogenetic analysis

Martin, A. O., Northrup, H., Ledbetter, D. H., Trask, B., Van den Engh, G., Le Beau, M. M., Beaudet, A. L., Gray, J. W., Sekhon, G., Krassikoff, N. & Booth, C., Jan 1 1988, In : American Journal of Medical Genetics. 31, 3, p. 643-654 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Use of restriction endonucleases and exonuclease III to expose halogenated pyrimidines for immunochemical staining

Dolbeare, F. & Gray, J. W., Nov 1988, In : Cytometry. 9, 6, p. 631-635 5 p.

Research output: Contribution to journalArticle

40 Scopus citations