• 67302 Citations
  • 113 h-Index
1971 …2020

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Article
2012

Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: Field cancerization or contaminating tumor cells?

Sadanandam, A., Lal, A., Benz, S. C., Eppenberger-Castori, S., Scott, G., Gray, J. W., Spellman, P., Waldman, F. & Benz, C. C., Dec 1 2012, In : Breast Cancer Research and Treatment. 136, 3, p. 693-703 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target

McElwee, J. L., Mohanan, S., Griffith, O. L., Breuer, H. C., Anguish, L. J., Cherrington, B. D., Palmer, A. M., Howe, L. R., Subramanian, V., Causey, C. P., Thompson, P. R., Gray, J. W. & Coonrod, S. A., Oct 30 2012, In : BMC cancer. 12, 500.

Research output: Contribution to journalArticle

63 Scopus citations

Integrating biological knowledge into variable selection: an empirical Bayes approach with an application in cancer biology

Hill, S. M., Neve, R. M., Bayani, N., Kuo, W. L., Ziyad, S., Spellman, P. T., Gray, J. W. & Mukherjee, S., May 11 2012, In : BMC bioinformatics. 13, 1, 94.

Research output: Contribution to journalArticle

16 Scopus citations

Lectin chromatography/mass spectrometry discovery workflow identifies putative biomarkers of aggressive breast cancers

Drake, P. M., Schilling, B., Niles, R. K., Prakobphol, A., Li, B., Jung, K., Cho, W., Braten, M., Inerowicz, H. D., Williams, K., Albertolle, M., Held, J. M., Iacovides, D., Sorensen, D. J., Griffith, O. L., Johansen, E., Zawadzka, A. M., Cusack, M. P., Allen, S., Gormley, M. & 6 others, Hall, S. C., Witkowska, H. E., Gray, J. W., Regnier, F., Gibson, B. W. & Fisher, S. J., Apr 6 2012, In : Journal of Proteome Research. 11, 4, p. 2508-2520 13 p.

Research output: Contribution to journalArticle

42 Scopus citations

Loss of cell-surface laminin anchoring promotes tumor growth and is associated with poor clinical outcomes

Akhavan, A., Griffith, O. L., Soroceanu, L., Leonoudakis, D., Luciani-Torres, M. G., Daemen, A., Gray, J. W. & Muschler, J. L., May 15 2012, In : Cancer Research. 72, 10, p. 2578-2588 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Optimization-based inference for temporally evolving networks with applications in biology

Chang, Y. H., Gray, J. & Tomlin, C., Dec 1 2012, In : Journal of Computational Biology. 19, 12, p. 1307-1323 17 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: Results from the I-SPY 1 TRIAL - CALGB 150007/150012, ACRIN 6657

Esserman, L. J., Berry, D. A., DeMichele, A., Carey, L., Davis, S. E., Buxton, M., Hudis, C., Gray, J. W., Perou, C., Yau, C., Livasy, C., Krontiras, H., Montgomery, L., Tripathy, D., Lehman, C., Liu, M. C., Olopade, O. I., Rugo, H. S., Carpenter, J. T., Dressler, L. & 8 others, Chhieng, D., Singh, B., Mies, C., Rabban, J., Chen, Y. Y., Giri, D., Van't Veer, L. & Hylton, N., Sep 10 2012, In : Journal of Clinical Oncology. 30, 26, p. 3242-3249 8 p.

Research output: Contribution to journalArticle

258 Scopus citations

Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress

Cheng, K. W., Agarwal, R., Mitra, S., Lee, J. S., Carey, M., Gray, J. W. & Mills, G. B., Feb 1 2012, In : EMBO Molecular Medicine. 4, 2, p. 125-141 17 p.

Research output: Contribution to journalArticle

47 Scopus citations

Subtype and pathway specific responses to anticancer compounds in breast cancer

Heiser, L. M., Sadanandam, A., Kuo, W. L., Benz, S. C., Goldstein, T. C., Ng, S., Gibb, W. J., Wang, N., Ziyad, S., Tong, F., Bayani, N., Hu, Z., Billig, J. I., Dueregger, A., Lewis, S., Jakkula, L., Korkola, J. E., Durinck, S., Pepin, F., Guan, Y. & 23 others, Purdom, E., Neuvial, P., Bengtsson, H., Wood, K. W., Smith, P. G., Vassilev, L. T., Hennessy, B. T., Greshock, J., Bachman, K. E., Hardwicke, M. A., Park, J. W., Marton, L. J., Wolf, D. M., Collisson, E. A., Neve, R. M., Mills, G. B., Speed, T. P., Feiler, H. S., Richard, F. W., Haussler, D., Stuart, J. M., Gray, J. W. & Spellman, P. T., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 2724-2729 6 p.

Research output: Contribution to journalArticle

274 Scopus citations

The transcription factor ZNF217 Is a prognostic biomarker and therapeutic target during breast cancer progression

Littlepage, L. E., Adler, A. S., Kouros-Mehr, H., Huang, G., Chou, J., Krig, S. R., Griffi th, O. L., Korkola, J. E., Qu, K., Lawson, D. A., Xue, Q., Sternlicht, M. D., Dijkgraaf, G. J. P., Yaswen, P., Rugo, H. S., Sweeney, C. A., Collins, C. C., Gray, J. W., Chang, H. Y. & Werb, Z., Jul 1 2012, In : Cancer discovery. 2, 7, p. 638-651 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors

Petrillo, L. A., Wolf, D. M., Kapoun, A. M., Wang, N. J., Barczak, A., Xiao, Y., Korkaya, H., Baehner, F., Lewicki, J., Wicha, M., Park, J. W., Spellman, P. T., Gray, J. W., Van'T Veer, L. & Esserman, L. J., Oct 1 2012, In : Breast Cancer Research and Treatment. 135, 3, p. 913-922 10 p.

Research output: Contribution to journalArticle

28 Scopus citations
2011

A new treasure in the breast cancer gene hunt

Spellman, P. & Gray, J., Apr 1 2011, In : Nature medicine. 17, 4, p. 422-423 2 p.

Research output: Contribution to journalArticle

13 Scopus citations

Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence

Fackler, M. J., Umbricht, C. B., Williams, D., Argani, P., Cruz, L. A., Merino, V. F., Teo, W. W., Zhang, Z., Huang, P., Visvananthan, K., Marks, J., Ethier, S., Gray, J. W., Wolff, A. C., Cope, L. M. & Sukumar, S., Oct 1 2011, In : Cancer Research. 71, 19, p. 6195-6207 13 p.

Research output: Contribution to journalArticle

137 Scopus citations

Integrated genomic analyses of ovarian carcinoma

Bell, D., Berchuck, A., Birrer, M., Chien, J., Cramer, D. W., Dao, F., Dhir, R., Disaia, P., Gabra, H., Glenn, P., Godwin, A. K., Gross, J., Hartmann, L., Huang, M., Huntsman, D. G., Iacocca, M., Imielinski, M., Kalloger, S., Karlan, B. Y., Levine, D. A. & 240 others, Mills, G., Morrison, C., Mutch, D., Olvera, N., Orsulic, S., Park, K., Petrelli, N., Rabeno, B., Rader, J. S., Sikic, B. I., Smith-Mccune, K., Sood, A. K., Bowtell, D., Penny, R., Testa, J. R., Chang, K., Dinh, H. H., Drummond, J. A., Fowler, G., Gunaratne, P., Hawes, A. C., Kovar, C. L., Lewis, L. R., Morgan, M. B., Newsham, I. F., Santibanez, J., Reid, J. G., Trevino, L. R., Wu, Y. Q., Wang, M., Muzny, D. M., Wheeler, D. A., Gibbs, R. A., Getz, G., Lawrence, M. S., Cibulskis, K., Sivachenko, A. Y., Sougnez, C., Voet, D., Wilkinson, J., Bloom, T., Ardlie, K., Fennell, T., Baldwin, J., Gabriel, S., Lander, E. S., Ding, L., Fulton, R. S., Koboldt, D. C., McLellan, M. D., Wylie, T., Walker, J., O'Laughlin, M., Dooling, D. J., Fulton, L., Abbott, R., Dees, N. D., Zhang, Q., Kandoth, C., Wendl, M., Schierding, W., Shen, D., Harris, C. C., Schmidt, H., Kalicki, J., Delehaunty, K. D., Fronick, C. C., Demeter, R., Cook, L., Wallis, J. W., Lin, L., Magrini, V. J., Hodges, J. S., Eldred, J. M., Smith, S. M., Pohl, C. S., Vandin, F., Raphael, B. J., Weinstock, G. M., Mardis, E. R., Wilson, R. K., Meyerson, M., Winckler, W., Verhaak, R. G. W., Carter, S. L., Mermel, C. H., Saksena, G., Nguyen, H., Onofrio, R. C., Hubbard, D., Gupta, S., Crenshaw, A., Ramos, A. H., Chin, L., Protopopov, A., Zhang, J., Kim, T. M., Perna, I., Xiao, Y., Zhang, H., Ren, G., Sathiamoorthy, N., Park, R. W., Lee, E., Park, P. J., Kucherlapati, R., Absher, D. M., Waite, L., Sherlock, G., Brooks, J. D., Li, J. Z., Xu, J., Myers, R. M., Laird, P. W., Cope, L., Herman, J. G., Shen, H., Weisenberger, D. J., Noushmehr, H., Pan, F., Triche, T., Berman, B. P., Van Den Berg, D. J., Buckley, J., Baylin, S. B., Spellman, P. T., Purdom, E., Neuvial, P., Bengtsson, H., Jakkula, L. R., Durinck, S., Han, J., Dorton, S., Marr, H., Choi, Y. G., Wang, V., Wang, N. J., Ngai, J., Conboy, J. G., Parvin, B., Feiler, H. S., Speed, T. P., Gray, J. W., Socci, N. D., Liang, Y., Taylor, B. S., Schultz, N., Borsu, L., Lash, A. E., Brennan, C., Viale, A., Sander, C., Ladanyi, M., Hoadley, K. A., Meng, S., Du, Y., Shi, Y., Li, L., Turman, Y. J., Zang, D., Helms, E. B., Balu, S., Zhou, X., Wu, J., Topal, M. D., Hayes, D. N., Perou, C. M., Wu, C. J., Shukla, S., Sivachenko, A., Jing, R., Liu, Y., Noble, M., Carter, H., Kim, D., Karchin, R., Korkola, J. E., Heiser, L. M., Cho, R. J., Hu, Z., Cerami, E., Olshen, A., Reva, B., Antipin, Y., Shen, R., Mankoo, P., Sheridan, R., Ciriello, G., Chang, W. K., Bernanke, J. A., Haussler, D., Benz, C. C., Stuart, J. M., Benz, S. C., Sanborn, J. Z., Vaske, C. J., Zhu, J., Szeto, C., Scott, G. K., Yau, C., Wilkerson, M. D., Zhang, N., Akbani, R., Baggerly, K. A., Yung, W. K., Weinstein, J. N., Shelton, T., Grimm, D., Hatfield, M., Morris, S., Yena, P., Rhodes, P., Sherman, M., Paulauskis, J., Millis, S., Kahn, A., Greene, J. M., Sfeir, R., Jensen, M. A., Chen, J., Whitmore, J., Alonso, S., Jordan, J., Chu, A., Barker, A., Compton, C., Eley, G., Ferguson, M., Fielding, P., Gerhard, D. S., Myles, R., Schaefer, C., Mills Shaw, K. R., Vaught, J., Vockley, J. B., Good, P. J., Guyer, M. S., Ozenberger, B., Peterson, J. & Thomson, E., Jun 30 2011, In : Nature. 474, 7353, p. 609-615 7 p.

Research output: Contribution to journalArticle

3923 Scopus citations

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

Wang, N. J., Sanborn, Z., Arnett, K. L., Bayston, L. J., Liao, W., Proby, C. M., Leigh, I. M., Collisson, E. A., Gordon, P. B., Jakkula, L., Pennypacker, S., Zou, Y., Sharma, M., North, J. P., Vemula, S. S., Mauro, T. M., Neuhaus, I. M., LeBoit, P. E., Hur, J. S., Park, K. & 13 others, Huh, N., Kwok, P. Y., Arron, S. T., Massion, P. P., Bale, A. E., Haussler, D., Cleaver, J. E., Gray, J. W., Spellman, P. T., South, A. P., Aster, J. C., Blacklow, S. C. & Cho, R. J., Oct 25 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 43, p. 17761-17766 6 p.

Research output: Contribution to journalArticle

260 Scopus citations

Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer

Krig, S. R., Frietze, S., Simion, C., Miller, J. K., Fry, W. H. D., Rafidi, H., Kotelawala, L., Qi, L., Griffith, O. L., Gray, J. W., Carraway, K. L. & Sweeney, C., Oct 1 2011, In : Molecular Cancer Research. 9, 10, p. 1406-1417 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Morphometic analysis of TCGA glioblastoma multiforme

Chang, H., Fontenay, G. V., Han, J., Cong, G., Baehner, F. L., Gray, J. W., Spellman, P. T. & Parvin, B., Dec 20 2011, In : BMC bioinformatics. 12, 484.

Research output: Contribution to journalArticle

33 Scopus citations

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

Collisson, E. A., Sadanandam, A., Olson, P., Gibb, W. J., Truitt, M., Gu, S., Cooc, J., Weinkle, J., Kim, G. E., Jakkula, L., Feiler, H. S., Ko, A. H., Olshen, A. B., Danenberg, K. L., Tempero, M. A., Spellman, P. T., Hanahan, D. & Gray, J. W., Apr 1 2011, In : Nature medicine. 17, 4, p. 500-503 4 p.

Research output: Contribution to journalArticle

616 Scopus citations

Temporal dissection of tumorigenesis in primary cancers

Durinck, S., Ho, C., Wang, N. J., Liao, W., Jakkula, L. R., Collisson, E. A., Pons, J., Chan, S. W., Lam, E. T., Chu, C., Park, K., Hong, S. W., Hur, J. S., Huh, N., Neuhaus, I. M., Yu, S. S., Grekin, R. C., Mauro, T. M., Cleaver, J. E., Kwok, P. Y. & 12 others, LeBoit, P. E., Getz, G., Cibulskis, K., Aster, J. C., Huang, H., Purdom, E., Li, J., Bolund, L., Arron, S. T., Gray, J. W., Spellman, P. T. & Cho, R. J., Jun 29 2011, In : Cancer discovery. 1, 2, p. 137-143 7 p.

Research output: Contribution to journalArticle

151 Scopus citations

Topographic enhancement mapping of the cancer-associated breast stroma using breast MRI

Nabavizadeh, N., Klifa, C., Newitt, D., Lu, Y., Chen, Y. Y., Hsu, H., Fisher, C., Tokayasu, T., Olshen, A. B., Spellman, P., Gray, J. W., Hylton, N. & Park, C. C., Apr 1 2011, In : Integrative Biology. 3, 4, p. 490-496 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
2010

Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer

Purcell, J. W., Davis, J., Reddy, M., Martin, S., Samayoa, K., Vo, H., Thomsen, K., Bean, P., Kuo, W. L., Ziyad, S., Billig, J., Feiler, H. S., Gray, J. W., Wood, K. W. & Cases, S., Jan 15 2010, In : Clinical Cancer Research. 16, 2, p. 566-576 11 p.

Research output: Contribution to journalArticle

54 Scopus citations

A technical assessment of the utility of reverse phase protein arrays for the study of the functional proteome in non-microdissected human breast cancers

Hennessy, B. T., Lu, Y., Gonzalez-Angulo, A. M., Carey, M. S., Myhre, S., Ju, Z., Davies, M. A., Liu, W., Coombes, K., Meric-Bernstam, F., Bedrosian, I., McGahren, M., Agarwal, R., Zhang, F., Overgaard, J., Alsner, J., Neve, R. M., Kuo, W. L., Gray, J. W., Borresen-Dale, A. L. & 1 others, Mills, G. B., Dec 1 2010, In : Clinical Proteomics. 6, 4, p. 129-151 23 p.

Research output: Contribution to journalArticle

145 Scopus citations

ERBB receptor regulation of ESX/ELF3 promotes invasion in breast epithelial cells

Coppe, J. P., Amend, C., Semeiks, J., Baehner, F. L., Bayani, N., Campisi, J., Benz, C. C., Gray, J. W. & Neve, R. M., Nov 19 2010, In : Open Cancer Journal. 3, SPEC. ISSUE 1, p. 89-100 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Exon-level microarray analyses identify alternative splicing programs in breast cancer

Lapuk, A., Marr, H., Jakkula, L., Pedro, H., Bhattacharya, S., Purdom, E., Hu, Z., Simpson, K., Pachter, L., Durinck, S., Wang, N., Parvin, B., Fontenay, G., Speed, T., Garbe, J., Stampfer, M., Bayandorian, H., Dorton, S., Clark, T. A., Schweitzer, A. & 5 others, Wyrobek, A., Feiler, H., Spellman, P., Conboy, J. & Gray, J. W., Jul 1 2010, In : Molecular Cancer Research. 8, 7, p. 961-974 14 p.

Research output: Contribution to journalArticle

85 Scopus citations

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

Weigelt, B., Lo, A. T., Park, C. C., Gray, J. W. & Bissell, M. J., Jul 1 2010, In : Breast Cancer Research and Treatment. 122, 1, p. 35-43 9 p.

Research output: Contribution to journalArticle

195 Scopus citations

High-throughput method for analyzing methylation of CpGs in targeted genomic regions

Nautiyal, S., Carlton, V. E. H., Lu, Y., Ireland, J. S., Flaucher, D., Moorhead, M., Gray, J. W., Spellman, P., Mindrinos, M., Berg, P. & Faham, M., Jul 13 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 28, p. 12587-12592 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Verhaak, R. G. W., Hoadley, K. A., Purdom, E., Wang, V., Qi, Y., Wilkerson, M. D., Miller, C. R., Ding, L., Golub, T., Mesirov, J. P., Alexe, G., Lawrence, M., O'Kelly, M., Tamayo, P., Weir, B. A., Gabriel, S., Winckler, W., Gupta, S., Jakkula, L., Feiler, H. S. & 13 others, Hodgson, J. G., James, C. D., Sarkaria, J. N., Brennan, C., Kahn, A., Spellman, P. T., Wilson, R. K., Speed, T. P., Gray, J. W., Meyerson, M., Getz, G., Perou, C. M. & Hayes, D. N., Jan 19 2010, In : Cancer Cell. 17, 1, p. 98-110 13 p.

Research output: Contribution to journalArticle

3664 Scopus citations

Linking changes in epithelial morphogenesis to cancer mutations using computational modeling

Rejniak, K. A., Wang, S. E., Bryce, N. S., Chang, H., Parvin, B., Jourquin, J., Estrada, L., Gray, J. W., Arteaga, C. L., Weaver, A. M., Quaranta, V. & Anderson, A. R. A., Aug 1 2010, In : PLoS computational biology. 6, 8, e1000900.

Research output: Contribution to journalArticle

29 Scopus citations

Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture

Han, J., Chang, H., Giricz, O., Lee, G. Y., Baehner, F. L., Gray, J. W., Bissell, M. J., Kenny, P. A. & Parvin, B., Feb 1 2010, In : PLoS computational biology. 6, 2, e1000684.

Research output: Contribution to journalArticle

59 Scopus citations

p27Kip1 mediates addiction of ovarian cancer cells to MYCC (c-MYC) and their dependence on MYC paralogs

Prathapam, T., Aleshin, A., Guan, Y., Gray, J. W. & Martin, G. S., Oct 15 2010, In : Journal of Biological Chemistry. 285, 42, p. 32529-32538 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Prediction of epigenetically regulated genes in breast cancer cell lines

Loss, L. A., Sadanandam, A., Durinck, S., Nautiyal, S., Flaucher, D., Carlton, V. E. H., Moorhead, M., Lu, Y., Gray, J. W., Faham, M., Spellman, P. & Parvin, B., Jun 4 2010, In : BMC bioinformatics. 11, 305.

Research output: Contribution to journalArticle

29 Scopus citations

Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

Creighton, C. J., Fu, X., Hennessy, B. T., Casa, A. J., Zhang, Y., Gonzalez-Angulo, A. M., Lluch, A., Gray, J. W., Brown, P. H., Hilsenbeck, S. G., Osborne, C. K., Mills, G. B., Lee, A. V. & Schiff, R., Jun 22 2010, In : Breast Cancer Research. 12, 3, R40.

Research output: Contribution to journalArticle

154 Scopus citations

Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities

Langland, G. T., Yannone, S. M., Langland, R. A., Nakao, A., Guan, Y., Long, S. B. T., Vonguyen, L., Chen, D. J., Gray, J. W. & Chen, F., Apr 1 2010, In : Oncology Reports. 23, 4, p. 1021-1026 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Restriction of receptor movement alters cellular response: Physical force sensing by EphA2

Salaita, K., Nair, P. M., Petit, R. S., Neve, R. M., Das, D., Gray, J. W. & Groves, J. T., Mar 12 2010, In : Science. 327, 5971, p. 1380-1385 6 p.

Research output: Contribution to journalArticle

239 Scopus citations

Sparse multitask regression for identifying common mechanism of response to therapeutic targets

Zhang, K., Gray, J. W. & Parvin, B., Jun 1 2010, In : Bioinformatics. 26, 12, p. i97-i105 btq181.

Research output: Contribution to journalArticle

21 Scopus citations

The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer

Hu, Z., Huang, G., Sadanandam, A., Gu, S., Lenburg, M. E., Pai, M., Bayani, N., Blakely, E. A., Gray, J. W. & Mao, J. H., Mar 8 2010, In : Breast Cancer Research. 12, 2, R18.

Research output: Contribution to journalArticle

74 Scopus citations
2009

A primer on regression methods for decoding cis-regulatory logic

Das, D., Pellegrini, M. & Gray, J. W., Jan 1 2009, In : PLoS computational biology. 5, 1, e1000269.

Research output: Contribution to journalArticle

13 Scopus citations

A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047

Kuo, W. L., Das, D., Ziyad, S., Bhattacharya, S., Gibb, W. J., Heiser, L. M., Sadanandam, A., Fontenay, G. V., Hu, Z., Wang, N., Bayani, N., Feiler, H. S., Neve, R. M., Wyrobek, A. J., Spellman, P. T., Marton, L. J. & Gray, J. W., Dec 14 2009, In : BMC Medicine. 7, 77.

Research output: Contribution to journalArticle

25 Scopus citations

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

Mirzoeva, O. K., Das, D., Heiser, L. M., Bhattacharya, S., Siwak, D., Gendelman, R., Bayani, N., Wang, N. J., Neve, R. M., Guan, Y., Hu, Z., Knight, Z., Feiler, H. S., Gascard, P., Parvin, B., Spellman, P. T., Shokat, K. M., Wyrobek, A. J., Bissell, M. J., McCormick, F. & 4 others, Kuo, W. L., Mills, G. B., Gray, J. W. & Korn, W. M., Jan 15 2009, In : Cancer Research. 69, 2, p. 565-572 8 p.

Research output: Contribution to journalArticle

274 Scopus citations

Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

Hennessy, B. T., Gonzalez-Angulo, A. M., Stemke-Hale, K., Gilcrease, M. Z., Krishnamurthy, S., Lee, J. S., Fridlyand, J., Sahin, A., Agarwal, R., Joy, C., Liu, W., Stivers, D., Baggerly, K., Carey, M., Lluch, A., Monteagudo, C., He, X., Weigman, V., Fan, C., Palazzo, J. & 7 others, Hortobagyi, G. N., Nolden, L. K., Wang, N. J., Valero, V., Gray, J. W., Perou, C. M. & Mills, G. B., May 15 2009, In : Cancer Research. 69, 10, p. 4116-4124 9 p.

Research output: Contribution to journalArticle

585 Scopus citations

Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts

Hodgson, J. G., Yeh, R. F., Ray, A., Wang, N. J., Smirnov, I., Yu, M., Hariono, S., Silber, J., Feiler, H. S., Gray, J. W., Spellman, P. T., Vandenberg, S. R., Berger, M. S. & James, C. D., Oct 1 2009, In : Neuro-Oncology. 11, 5, p. 477-487 11 p.

Research output: Contribution to journalArticle

88 Scopus citations

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

Wang, Y., Carlton, V. E., Karlin-Neumann, G., Sapolsky, R., Zhang, L., Moorhead, M., Wang, Z. C., Richardson, A. L., Warren, R., Walther, A., Bondy, M., Sahin, A., Krahe, R., Tuna, M., Thompson, P. A., Spellman, P. T., Gray, J. W., Mills, G. B. & Faham, M., Apr 6 2009, In : BMC Medical Genomics. 2, 8.

Research output: Contribution to journalArticle

75 Scopus citations

Immutable functional attributes of histologic grade revealed by context-independent gene expression in primary breast cancer cells

Dairkee, S. H., Sayeed, A., Luciani, G., Champion, S., Zhenhang, M., Jakkula, L. R., Feiler, H. S., Gray, J. W. & Moore, D. H., Oct 1 2009, In : Cancer Research. 69, 19, p. 7826-7834 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Integrated analysis of breast cancer cell lines reveals unique signaling pathways

Heiser, L. M., Wang, N. J., Talcott, C. L., Laderoute, K. R., Knapp, M., Guan, Y., Hu, Z., Ziyad, S., Weber, B. L., Laquerre, S., Jackson, J. R., Wooster, R. F., Kuo, W., Gray, J. W. & Spellman, P. T., Mar 25 2009, In : Genome biology. 10, 3, R31.

Research output: Contribution to journalArticle

51 Scopus citations

Integrative analysis of cyclin protein levels identifies cyclin B1 as a classifier and predictor of outcomes in breast cancer

Agarwal, R., Gonzalez-Angulo, A. M., Myhre, S., Carey, M., Lee, J. S., Overgaard, J., Alsner, J., Stemke-Hale, K., Lluch, A., Neve, R. M., Kuo, W. L., Sorlie, T., Sahin, A., Valero, V., Keyomarsi, K., Gray, J. W., Borresen-Dale, A. L., Mills, G. B. & Hennessy, B. T., Jun 1 2009, In : Clinical Cancer Research. 15, 11, p. 3654-3662 9 p.

Research output: Contribution to journalArticle

99 Scopus citations

LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer

Ong, D. C. T., Ho, Y. M., Rudduck, C., Chin, K., Kuo, W. L., Lie, D. K. H., Chua, C. L. M., Tan, P. H., Eu, K. W., Seow-Choen, F., Wong, C. Y., Hong, G. S., Gray, J. W. & Lee, A. S. G., Nov 1 2009, In : Oncogene. 28, 47, p. 4189-4200 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Picomolar sensitivity MRI and photoacoustic imaging of cobalt nanoparticles

Bouchard, L. S., Anwar, M. S., Liu, G. L., Hann, B., Xie, Z. H., Gray, J. W., Wang, X., Pines, A. & Chen, F. F., Mar 17 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 11, p. 4085-4089 5 p.

Research output: Contribution to journalArticle

139 Scopus citations

Sparse combinatorial inference with an application in cancer biology

Mukherjee, S., Pelech, S., Neve, R. M., Kuo, W. L., Ziyad, S., Spellman, P. T., Gray, J. W. & Speed, T. P., Jan 1 2009, In : Bioinformatics. 25, 2, p. 265-271 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Yin Yang 1 modulates taxane response in epithelial ovarian cancer

Matsumura, N., Huang, Z., Baba, T., Lee, P. S., Barnett, J. C., Mori, S., Chang, J. T., Kuo, W. L., Gusberg, A. H., Whitaker, R. S., Gray, J. W., Fujii, S., Berchuck, A. & Murphy, S. K., Feb 1 2009, In : Molecular Cancer Research. 7, 2, p. 210-220 11 p.

Research output: Contribution to journalArticle

43 Scopus citations
2008

A human breast cell model of preinvasive to invasive transition

Rizki, A., Weaver, V. M., Lee, S. Y., Rozenberg, G. I., Chin, K., Myers, C. A., Bascom, J. L., Mott, J. D., Semeiks, J. R., Grate, L. R., Mian, I. S., Borowsky, A. D., Jensen, R. A., Idowu, M. O., Chen, F., Chen, D. J., Petersen, O. W., Gray, J. W. & Bissell, M. J., Mar 1 2008, In : Cancer Research. 68, 5, p. 1378-1387 10 p.

Research output: Contribution to journalArticle

107 Scopus citations