• 67731 Citations
  • 113 h-Index
1971 …2020

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Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma

Sonoda, I., Imoto, I., Inoue, J., Shibata, T., Shimada, Y., Chin, K., Imamura, M., Amagasa, T., Gray, J. W., Hirohashi, S. & Inazawa, J., Jun 1 2004, In : Cancer Research. 64, 11, p. 3741-3747 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

Fringe‐scan flow cytometry

Mullikin, J., Norgren, R., Lucas, J. & Gray, J., Mar 1988, In : Cytometry. 9, 2, p. 111-120 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death

Guest, S. T., Kratche, Z. R., Irish, J. C., Wilson, R. C., Haddad, R., Gray, J. W., Garrett-Mayer, E. & Ethier, S. P., 2016, In : Oncotarget. 7, 24, p. 36138-36153 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer

Seviour, E. G., Sehgal, V., Lu, Y., Luo, Z., Moss, T., Zhang, F., Hill, S. M., Liu, W., Maiti, S. N., Cooper, L., Azencot, R., Lopez-Berestein, G., Rodriguez-Aguayo, C., Roopaimoole, R., Pecot, C., Sood, A. K., Mukherjee, S., Gray, J. W., Mills, G. B. & Ram, P. T., Feb 11 2016, In : Oncogene. 35, 6, p. 691-701 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Gamma-normal-gamma mixture model for detecting differentially methylated loci in three breast cancer cell lines

Khalili, A., Potter, D., Yan, P., Li, L., Gray, J., Huang, T. & Lin, S., 2007, In : Cancer Informatics. 3, p. 43-54 12 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Gene encoding protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

Anand, N., Murthy, S., Amann, G., Wernick, M., Porter, L. A., Cukier, I. H., Collins, C., Gray, J. W., Diebold, J., Demetrick, D. J. & Lee, J. M., Jul 2002, In : Nature genetics. 31, 3, p. 301-305 5 p.

Research output: Contribution to journalArticle

193 Scopus citations

Generation of five high-complexity painting probe libraries from flow-sorted mouse chromosomes

Weier, H. U. G., Polikoff, D., Fawcett, J. J., Greulich, K. M., Lee, K. H., Cram, S., Chapman, V. M. & Gray, J. W., Jun 1994, In : Genomics. 21, 3, p. 641-644 4 p.

Research output: Contribution to journalArticle

56 Scopus citations
18 Scopus citations

Genetic Analysis of Benign, Low-Grade, and High-Grade Ovarian Tumors

Iwabuchi, H., Sakamoto, M., Sakunaga, H., Ma, Y. Y., Carcangiu, M. L., Pinkel, D., Yang-Feng, T. L. & Gray, J. W., Dec 15 1995, In : Cancer Research. 55, 24, p. 6172-6180 9 p.

Research output: Contribution to journalArticle

273 Scopus citations

Genetic analysis using genomic representations

Lucito, R., Nakimura, M., West, J. A., Han, Y., Chin, K., Jensen, K., Mccombie, R., Gray, J. W. & Wigler, M., Apr 14 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 8, p. 4487-4492 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

Genetic Differences in Transcript Responses to Low-Dose Ionizing Radiation Identify Tissue Functions Associated with Breast Cancer Susceptibility

Snijders, A. M., Marchetti, F., Bhatnagar, S., Duru, N., Han, J., Hu, Z., Mao, J. H., Gray, J. W. & Wyrobek, A. J., Oct 15 2012, In : PloS one. 7, 10, e45394.

Research output: Contribution to journalArticle

16 Scopus citations

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

Hu, Z., Mao, J. H., Curtis, C., Huang, G., Gu, S., Heiser, L., Lenburg, M. E., Korkola, J. E., Bayani, N., Samarajiwa, S., Seoane, J. A., Dane, M., Esch, A., Feiler, H. S., Wang, N. J., Hardwicke, M. A., Laquerre, S., Jackson, J., Wood, K., Weber, B. & 5 others, Spellman, P. T., Aparicio, S., Wooster, R., Caldas, C. & Gray, J. W., Jul 1 2016, In : Breast Cancer Research. 18, 1, 70.

Research output: Contribution to journalArticle

6 Scopus citations

Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas

Hodgson, G., Hager, J. H., Volik, S., Hariono, S., Wernick, M., Moore, D., Albertson, D. G., Pinkel, D., Collins, C., Hanahan, D. & Gray, J. W., Jan 1 2001, In : Nature genetics. 29, 4, p. 459-464 6 p.

Research output: Contribution to journalArticle

250 Scopus citations

Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors

Hackett, C. S., Hodgson, J. G., Law, M. E., Fridlyand, J., Osoegawa, K., De Jong, P. J., Nowak, N. J., Pinkel, D., Albertson, D. G., Jain, A., Jenkins, R., Gray, J. W. & Weiss, W. A., Sep 1 2003, In : Cancer Research. 63, 17, p. 5266-5273 8 p.

Research output: Contribution to journalArticle

89 Scopus citations

Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome

Engler, D. A., Gupta, S., Growdon, W. B., Drapkin, R. I., Nitta, M., Sergent, P. A., Allred, S. F., Gross, J., Deavers, M. T., Kuo, W. L., Karlan, B. Y., Rueda, B. R., Orsulic, S., Gershenson, D. M., Birrer, M. J., Gray, J. W. & Mohapatra, G., Feb 15 2012, In : PloS one. 7, 2, e30996.

Research output: Contribution to journalArticle

25 Scopus citations

Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence

Fackler, M. J., Umbricht, C. B., Williams, D., Argani, P., Cruz, L. A., Merino, V. F., Teo, W. W., Zhang, Z., Huang, P., Visvananthan, K., Marks, J., Ethier, S., Gray, J. W., Wolff, A. C., Cope, L. M. & Sukumar, S., Oct 1 2011, In : Cancer Research. 71, 19, p. 6195-6207 13 p.

Research output: Contribution to journalArticle

137 Scopus citations

Genome-wide perturbations by miRNAs map onto functional cellular pathways, identifying regulators of chromatin modifiers

Moss, T. J., Luo, Z., Seviour, E. G., Sehgal, V., Lu, Y., Hill, S. M., Rupaimoole, R., Lee, J. S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Sood, A. K., Azencott, R., Gray, J., Mukherjee, S., Mills, G. & Ram, P. T., Sep 28 2015, In : npj Systems Biology and Applications. 1, 15001.

Research output: Contribution to journalArticle

2 Scopus citations

Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: Field cancerization or contaminating tumor cells?

Sadanandam, A., Lal, A., Benz, S. C., Eppenberger-Castori, S., Scott, G., Gray, J. W., Spellman, P., Waldman, F. & Benz, C. C., Dec 1 2012, In : Breast Cancer Research and Treatment. 136, 3, p. 693-703 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

Chin, K., DeVries, S., Fridlyand, J., Spellman, P. T., Roydasgupta, R., Kuo, W. L., Lapuk, A., Neve, R. M., Qian, Z., Ryder, T., Chen, F., Feiler, H., Tokuyasu, T., Kingsley, C., Dairkee, S., Meng, Z., Chew, K., Pinkel, D., Jain, A., Ljung, B. M. & 4 others, Esserman, L., Albertson, D. G., Waldman, F. M. & Gray, J. W., Dec 1 2006, In : Cancer Cell. 10, 6, p. 529-541 13 p.

Research output: Contribution to journalArticle

925 Scopus citations

Genomics of islet cell carcinogenesis

Hager, J., Hodgson, G., Collins, C., Tsai, F. Y., Huszar, D., Gray, J. & Hanahan, D., Apr 2001, In : Nature genetics. 27, 4S, p. 57-58 2 p.

Research output: Contribution to journalArticle

Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target

Timmerman, L. A., Holton, T., Yuneva, M., Louie, R. J., Padró, M., Daemen, A., Hu, M., Chan, D. A., Ethier, S. P., van'tVeer, L. J., Polyak, K., McCormick, F. & Gray, J. W., Oct 14 2013, In : Cancer Cell. 24, 4, p. 450-465 16 p.

Research output: Contribution to journalArticle

228 Scopus citations

Heat shock proteins within the mammalian cell cycle: Relationship to thermal sensitivity, thermal tolerance, and cell cycle progression

Rice, G., Laszlo, A., Li, G., Gray, J. & Dewey, W., Feb 1986, In : Journal of Cellular Physiology. 126, 2, p. 291-297 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

HER2 reactivation through acquisition of the HER2 L755S mutation as a mechanism of acquired resistance to HER2-targeted therapy in HER2+ breast cancer

Xu, X., De Angelis, C., Burke, K. A., Nardone, A., Hu, H., Qin, L., Veeraraghavan, J., Sethunath, V., Heiser, L., Wang, N., Ng, C. K. Y., Chen, E. S., Renwick, A., Wang, T., Nanda, S., Shea, M., Mitchell, T., Rajendran, M., Waters, I., Zabransky, D. J. & 14 others, Scott, K. L., Gutierrez, C., Nagi, C., Geyer, F. C., Chamness, G. C., Park, B. H., Shaw, C. A., Hilsenbeck, S. G., Rimawi, M. F., Gray, J., Weigelt, B., Reis-Filho, J. S., Osborne, C. K. & Schiff, R., Sep 1 2017, In : Clinical Cancer Research. 23, 17, p. 5123-5134 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

Weigelt, B., Lo, A. T., Park, C. C., Gray, J. W. & Bissell, M. J., Jul 1 2010, In : Breast Cancer Research and Treatment. 122, 1, p. 35-43 9 p.

Research output: Contribution to journalArticle

197 Scopus citations

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

Wang, Y., Carlton, V. E., Karlin-Neumann, G., Sapolsky, R., Zhang, L., Moorhead, M., Wang, Z. C., Richardson, A. L., Warren, R., Walther, A., Bondy, M., Sahin, A., Krahe, R., Tuna, M., Thompson, P. A., Spellman, P. T., Gray, J. W., Mills, G. B. & Faham, M., 2009, In : BMC Medical Genomics. 2, 8.

Research output: Contribution to journalArticle

75 Scopus citations

High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays

Pinkel, D., Segraves, R., Sudar, D., Clark, S., Poole, I., Kowbel, D., Collins, C., Kuo, W. L., Chen, C., Zhai, Y., Dairkee, S. H., Ljung, B. M., Gray, J. W. & Albertson, D. G., Oct 15 1998, In : Nature genetics. 20, 2, p. 207-211 5 p.

Research output: Contribution to journalArticle

1718 Scopus citations

High resolution chromosome analysis: one and two parameter flow cytometry

Gray, J. W., Langlois, R. G., Carrano, A. V., Burkhart-Schulte, K. & Van Dilla, M. A., Jan 1 1979, In : Chromosoma. 73, 1, p. 9-27 19 p.

Research output: Contribution to journalArticle

92 Scopus citations

High-resolution mapping of genotype-phenotype relationships in cri du chat syndrome using array comparative genomic hybridization

Zhang, X., Snijders, A., Segraves, R., Zhang, X., Niebuhr, A., Albertson, D., Yang, H., Gray, J., Niebuhr, E., Bolund, L. & Pinkel, D., Feb 2005, In : American Journal of Human Genetics. 76, 2, p. 312-326 15 p.

Research output: Contribution to journalArticle

114 Scopus citations

High sensitivity, high resolution physical mapping by fluorescence in situ hybridization on to individual straightened DNA molecules

Wang, M., Duell, T., Gray, J. W. & Weier, H. U. G., 1996, In : Bioimaging. 4, 2, p. 73-83 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

High-speed cell analysis and sorting with flow systems: Biological applications and new approaches

Van Dilla, M. A., Steinmetz, L. L., Davis, D. T., Calver, R. N. & Gray, J., Feb 1974, In : IEEE Transactions on Nuclear Science. 21, 1, p. 714-720 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

High speed chromosome measurement and sorting using flow systems

Carrano, A. V., Gray, J. W., Balhorn, R. L. & Moore, D. H., Jan 1 1976, In : Unknown Journal. No. 397, p. No.293

Research output: Contribution to journalArticle

High-speed chromosome sorting

Gray, J. W., Dean, P. N., Fuscoe, J. C., Peters, D. C., Trask, B. J., Van Den Engh, G. J. & Van Dilla, M. A., Jan 1 1987, In : Science. 238, 4825, p. 323-329 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

High speed quantitative karyotyping by flow microfluorometry

Gray, J. W., Carrano, A. V., Moore, D. H., Steinmetz, L. L., Minkler, J., Mayall, B. H., Mendelsohn, M. L. & Van Dilla, M. A., Jan 1 1975, In : Unknown Journal. 21, 9, p. 1258-1262 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

High-throughput method for analyzing methylation of CpGs in targeted genomic regions

Nautiyal, S., Carlton, V. E. H., Lu, Y., Ireland, J. S., Flaucher, D., Moorhead, M., Gray, J. W., Spellman, P., Mindrinos, M., Berg, P. & Faham, M., Jul 13 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 28, p. 12587-12592 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

High-throughput single-particle tracking reveals 1 nested membrane domains that dictate krasg12d 2 diffusion and trafficking

Lee, Y., Phelps, C., Huang, T., Mostofian, B., Wu, L., Zhang, Y., Tao, K., Chang, Y. H., Stork, P. J. S., Gray, J. W., Zuckerman, D. M. & Nan, X., Nov 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Human chromosome isolation from short-term lymphocyte culture for flow cytometry

Yu, L. C., Aten, J., Gray, J. & Carrano, A. V., Dec 1 1981, In : Nature. 293, 5828, p. 154-155 2 p.

Research output: Contribution to journalArticle

32 Scopus citations

Human chromosome–specific DNA libraries: Construction and availability

Van Dilla, M. A., Deaven, L. L., Albright, K. L., Allen, N. A., Aubuchon, M. R., Bartholdi, M. F., Brown, N. C., Campbell, E. W., Carrano, A. V., Clark, L. M., Cram, L. S., Crawford, B. D., Fuscoe, J. C., Gray, J. W., Hildebrand, C. E., Jackson, P. J., Jett, J. H., Longmire, J. L., Lozes, C. R., Luedemann, M. L. & 11 others, Martin, J. C., McNinch, J. S., Meincke, L. J., Mendelsohn, M. L., Meyne, J., Moyzis, R. K., Munk, A. C., Perlman, J., Peters, D. C., Silva, A. J. & Trask, B. J., Jun 1986, In : Bio/Technology. 4, 6, p. 537-552 16 p.

Research output: Contribution to journalArticle

110 Scopus citations

HYAL1(LUCA-1), a candidate tumor suppressor gene on chromosome 3p21.3, is inactivated in head and neck squamous cell carcinomas by aberrant splicing of pre-mRNA

Frost, G. I., Mohapatra, G., Wong, T. M., Csóka, A. B., Gray, J. W. & Stern, R., Feb 17 2000, In : Oncogene. 19, 7, p. 870-877 8 p.

Research output: Contribution to journalArticle

Open Access
70 Scopus citations

Identification and quantification of AKT isoforms and phosphoforms in breast cancer using a novel nanofluidic immunoassay

Iacovides, D. C., Johnson, A. B., Wang, N., Boddapati, S., Korkola, J. & Gray, J. W., Nov 1 2013, In : Molecular and Cellular Proteomics. 12, 11, p. 3210-3220 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Identification of a novel homozygous deletion region at 6q23.1 in medulloblastomas using high-resolution array: Comparative genomic hybridization analysis

Hui, A. B. Y., Takano, H., Lo, K. W., Kuo, W. L., Lam, C. N. Y., Tong, C. Y. K., Chang, Q., Gray, J. W. & Ng, H. K., Jul 1 2005, In : Clinical Cancer Research. 11, 13, p. 4707-4716 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Identification of Frequent Novel Genetic Alterations in Small Cell Lung Carcinoma

Levin, N. A., Brzoska, P., Gupta, N., Gray, J. W. & Christman, M. F., Oct 1 1994, In : Cancer Research. 54, 19, p. 5086-5091 6 p.

Research output: Contribution to journalArticle

80 Scopus citations

Identification of gene regulation patterns underlying both oestrogen- and tamoxifen-stimulated cell growth through global gene expression profiling in breast cancer cells

Fan, P., Cunliffe, H. E., Griffith, O. L., Agboke, F. A., Ramos, P., Gray, J. W. & Jordan, V. C., Nov 2014, In : European Journal of Cancer. 50, 16, p. 2877-2886 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Identification of novel regions of altered DNA copy number in small cell lung tumors

Levin, N. A., Bnorka, P. M., Warnock, M. L., Gray, J. W. & Christman, M. F., Jul 1995, In : Genes, Chromosomes and Cancer. 13, 3, p. 175-185 11 p.

Research output: Contribution to journalArticle

83 Scopus citations

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target

McElwee, J. L., Mohanan, S., Griffith, O. L., Breuer, H. C., Anguish, L. J., Cherrington, B. D., Palmer, A. M., Howe, L. R., Subramanian, V., Causey, C. P., Thompson, P. R., Gray, J. W. & Coonrod, S. A., Oct 30 2012, In : BMC cancer. 12, 500.

Research output: Contribution to journalArticle

65 Scopus citations

IL-10 and integrin signaling pathways are associated with head and neck cancer progression

Bornstein, S., Schmidt, M., Choonoo, G., Levin, T., Gray, J., Thomas, C., Wong, M. & McWeeney, S., Jan 8 2016, In : BMC Genomics. 17, 1, 38.

Research output: Contribution to journalArticle

25 Scopus citations

Immunofluorescent detection of histone 2B on metaphase chromosomes using flow cytometry

Trask, B., van den Engh, G., Gray, J., Vanderlaan, M. & Turner, B., Oct 1 1984, In : Chromosoma. 90, 4, p. 295-302 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Immutable functional attributes of histologic grade revealed by context-independent gene expression in primary breast cancer cells

Dairkee, S. H., Sayeed, A., Luciani, G., Champion, S., Zhenhang, M., Jakkula, L. R., Feiler, H. S., Gray, J. W. & Moore, D. H., Oct 1 2009, In : Cancer Research. 69, 19, p. 7826-7834 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
7 Scopus citations

Improved resolution of flow cytometric measurements of hoechst‐ and chromomycin‐A3‐stained human chromosomes after addition of citrate and sulfite

Engh, G. V. D., Trask, B., Gray, J. & Lansdorp, P., May 1988, In : Cytometry. 9, 3, p. 266-270 5 p.

Research output: Contribution to journalArticle

48 Scopus citations

Increased Copy Number at 20ql3 in Breast Cancer: Defining the Critical Region and Exclusion of Candidate Genes1

Tanner, M. M., Tirkkonen, M., Kallioniemi, A., Collins, C., Stokke, T., Karhu, R., Kowbel, D., Shadravan, F., Hintz, M., Kuo, W. L., Waldman, F. M., Isola, J. J., Gray, J. W. & Kallioniemi, O. P., Aug 1994, In : Cancer Research. 54, 16, p. 4257-4260 4 p.

Research output: Contribution to journalArticle

166 Scopus citations