• 67731 Citations
  • 113 h-Index
1971 …2020

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Differential staining of human and murine chromatin in situ by hybridization with species-specific satellite DNA probes

Weier, H. U. G., Zitzelsberger, H. F. & Gray, J. W., Feb 14 1992, In : Biochemical and Biophysical Research Communications. 182, 3, p. 1313-1319 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

Risom, T., Langer, E. M., Chapman, M. P., Rantala, J., Fields, A. J., Boniface, C., Alvarez, M. J., Kendsersky, N. D., Pelz, C. R., Johnson-Camacho, K., Dobrolecki, L. E., Chin, K., Aswani, A. J., Wang, N. J., Califano, A., Lewis, M. T., Tomlin, C. J., Spellman, P. T., Adey, A., Gray, J. W. & 1 others, Sears, R. C., Dec 1 2018, In : Nature communications. 9, 1, 3815.

Research output: Contribution to journalArticle

29 Scopus citations

DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters

Sutton, M. N., Lu, Z., Li, Y. C., Zhou, Y., Huang, T., Reger, A. S., Hurwitz, A. M., Palzkill, T., Logsdon, C., Liang, X., Gray, J. W., Nan, X., Hancock, J., Wahl, G. M. & Bast, R. C., Dec 10 2019, In : Cell Reports. 29, 11, p. 3448-3459.e6

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Disentangling multidimensional spatio-temporal data into their common and aberrant responses

Chang, Y. H., Korkola, J., Amin, D. N., Moasser, M. M., Carmena, J. M., Gray, J. W. & Tomlin, C. J., Apr 22 2015, In : PloS one. 10, 4, e0121607.

Research output: Contribution to journalArticle

1 Scopus citations
5 Scopus citations

DNA copy number changes associated with characteristic LOH in islet cell carcinomas of transgenic mice

Shi, Y. P., Naik, P., Dietrich, W. F., Gray, J. W., Hanahan, D. & Pinkel, D., Jun 14 1997, In : Genes Chromosomes and Cancer. 19, 2, p. 104-111 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Do breast cancer cell lines provide a relevant model of the patient tumor methylome?

Cope, L. M., Fackler, M. J., Lopez-Bujanda, Z., Wolff, A. C., Visvanathan, K., Gray, J. W., Sukumar, S. & Umbricht, C. B., Aug 26 2014, In : PloS one. 9, 8, e105545.

Research output: Contribution to journalArticle

10 Scopus citations

Dose-dependent response of KHT tumour cells to ARA-C

Dolbeare, F., Pallavicini, M. G. & Gray, J. W., Jan 1 1982, In : Cell and Tissue Kinetics. 15, 6, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Double labeling with iodo- and bromodeoxyuridine for cell kinetic studies

Shibui, S., Hoshino, T., Vanderlaan, M. & Gray, J. W., Jan 1 1989, In : Journal of Histochemistry and Cytochemistry. 37, 7, p. 1007-1011 5 p.

Research output: Contribution to journalArticle

Open Access
73 Scopus citations

Effect of methylglyoxal-bis (guanylhydrazone), an inhibitor of spermidine and spermine synthesis, on cell cycle traverse

Heby, O., Marton, L. J., Wilson, C. B. & Gray, J. W., Sep 1977, In : European Journal of Cancer (1965). 13, 9, p. 1009-1017 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Effects of methotrexate on transfected DNA stability in mammalian cells

Pallavicini, M. G., Deteresa, P. S., Rosette, C., Gray, J. W. & Wurm, F. M., Jan 1990, In : Molecular and cellular biology. 10, 1, p. 401-404 4 p.

Research output: Contribution to journalArticle

Open Access
76 Scopus citations

Efficient, interactive, and three-dimensional segmentation of cell nuclei in thick tissue sections

Lockett, S. J., Sudar, D., Thompson, C. T., Pinkel, D. & Gray, J. W., Apr 1 1998, In : Cytometry. 31, 4, p. 275-286 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

EGFR intron 1 polymorphism in Asian populations and its correlation with EGFR gene expression and amplification in breast tumor tissues

Zhou, Q., Yin, B. C., Jada, S. R., Wan, T. L., Kuo, W. L., Gray, J. W., Lee, A. S. G. & Chowbay, B., Nov 2006, In : Cancer Biology and Therapy. 5, 11, p. 1445-1449 5 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer

Mukhtar, R. A., Moore, A. P., Tandon, V. J., Nseyo, O., Twomey, P., Adisa, C. A., Eleweke, N., Au, A., Baehner, F. L., Moore, D. H., McGrath, M. S., Olopade, O. I., Gray, J. W., Campbell, M. J. & Esserman, L. J., Nov 1 2012, In : Annals of surgical oncology. 19, 12, p. 3979-3986 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Endocytic trafficking of laminin is controlled by dystroglycan and is disrupted in cancers

Leonoudakis, D., Huang, G., Akhavan, A., Fata, J. E., Singh, M., Gray, J. W. & Muschler, J. L., Jan 1 2014, In : Journal of Cell Science. 127, 22, p. 4894-4903 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

End-sequence profiling: Sequence-based analysis of aberrant genomes

Volik, S., Zhao, S., Chin, K., Brebner, J. H., Herndon, D. R., Tao, Q., Kowbel, D., Huang, G., Lapuk, A., Kuo, W. L., Magrane, G., De Jong, P., Gray, J. W. & Collins, C., Jun 24 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 13, p. 7696-7701 6 p.

Research output: Contribution to journalArticle

111 Scopus citations

Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer

Zhou, Y., Yau, C., Gray, J. W., Chew, K., Dairkee, S. H., Moore, D. H., Eppenberger, U., Eppenberger-Castori, S. & Benz, C. C., Apr 25 2007, In : BMC cancer. 7, 59.

Research output: Contribution to journalArticle

141 Scopus citations

Enrichment of murine hemopoietic clonogenic cells by multivariate analyses and sorting

Pallavicini, M. G., Summers, L. J., Dean, P. N. & Gray, J. W., Dec 1 1985, In : Experimental hematology. 13, 11, p. 1173-1181 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Enzymatic production of single-stranded DNA as a target for fluorescence in situ hybridization

van Dekken, H., Pinkel, D., Mullikin, J. & Gray, J. W., Sep 1 1988, In : Chromosoma. 97, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Epigenomic inactivation of RasGAPs activates RAS signaling in a subset of luminal B breast cancers

Sears, R. & Gray, J., Feb 1 2017, In : Cancer Discovery. 7, 2, p. 131-133 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization

Kallioniemi, O. P., Kallioniemi, A., Kurisu, W., Thor, A., Chen, L. C., Smith, H. S., Waldman, F. M., Pinkel, D. & Gray, J. W., Jun 22 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 12, p. 5321-5325 5 p.

Research output: Contribution to journalArticle

Open Access
444 Scopus citations

ERBB receptor regulation of ESX/ELF3 promotes invasion in breast epithelial cells

Coppe, J. P., Amend, C., Semeiks, J., Baehner, F. L., Bayani, N., Campisi, J., Benz, C. C., Gray, J. W. & Neve, R. M., Nov 19 2010, In : Open Cancer Journal. 3, SPEC. ISSUE 1, p. 89-100 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Estimation of the frequency of malformed sperm by slit scan flow cytometry

Halamka, J., Gray, J. W., Gledhill, B. L., Lake, S. & Wyrobek, A. J., Jul 1984, In : Cytometry. 5, 4, p. 333-338 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

ESX: A structurally unique Ets overexpressed early during human breast tumorigenesis

Chang, C. H., Scott, G. K., Kuo, W. L., Xiong, X., Suzdaltseva, Y., Park, J. W., Sayre, P., Erny, K., Collins, C., Gray, J. W. & Benz, C. C., Jan 1 1997, In : Oncogene. 14, 13, p. 1617-1622 6 p.

Research output: Contribution to journalArticle

Open Access
151 Scopus citations

Evidence of a dominant transcriptional pathway which regulates an undifferentiated and complete metastatic phenotype

Barsky, S. H., Sternlicht, M. D., Safarians, S., Nguyen, M., Chin, K., Stewart, S. D., Hiti, A. L. & Gray, J. W., Jan 1 1997, In : Oncogene. 15, 17, p. 2077-2091 15 p.

Research output: Contribution to journalArticle

16 Scopus citations

Exact reconstruction of gene regulatory networks using compressive sensing

Chang, Y. H., Gray, J. W. & Tomlin, C. J., Dec 14 2014, In : BMC bioinformatics. 15, 1, 400.

Research output: Contribution to journalArticle

22 Scopus citations

Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease

Butler, T. M., Johnson-Camacho, K., Peto, M., Wang, N. J., Macey, T. A., Korkola, J. E., Koppie, T. M., Corless, C. L., Gray, J. W. & Spellman, P. T., Aug 28 2015, In : PloS one. 10, 8, e0136407.

Research output: Contribution to journalArticle

65 Scopus citations

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

Shain, A. H., Garrido, M., Botton, T., Talevich, E., Yeh, I., Sanborn, J. Z., Chung, J., Wang, N. J., Kakavand, H., Mann, G. J., Thompson, J. F., Wiesner, T., Roy, R., Olshen, A. B., Gagnon, A., Gray, J. W., Huh, N., Hur, J. S., Busam, K. J., Scolyer, R. A. & 3 others, Cho, R. J., Murali, R. & Bastian, B. C., Sep 29 2015, In : Nature genetics. 47, 10, p. 1194-1199 6 p.

Research output: Contribution to journalArticle

108 Scopus citations

Exon-level microarray analyses identify alternative splicing programs in breast cancer

Lapuk, A., Marr, H., Jakkula, L., Pedro, H., Bhattacharya, S., Purdom, E., Hu, Z., Simpson, K., Pachter, L., Durinck, S., Wang, N., Parvin, B., Fontenay, G., Speed, T., Garbe, J., Stampfer, M., Bayandorian, H., Dorton, S., Clark, T. A., Schweitzer, A. & 5 others, Wyrobek, A., Feiler, H., Spellman, P., Conboy, J. & Gray, J. W., Jul 2010, In : Molecular Cancer Research. 8, 7, p. 961-974 14 p.

Research output: Contribution to journalArticle

86 Scopus citations

Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle

Kurki, P., Vanderlaan, M., Dolbeare, F., Gray, J. & Tan, E. M., Sep 1986, In : Experimental Cell Research. 166, 1, p. 209-219 11 p.

Research output: Contribution to journalArticle

423 Scopus citations
8 Scopus citations

Factors that Determine the in vivo Dose-Response Relationship for Stable Chromosome Aberrations in A-Bomb Survivors

Awa, A. A., Nakano, M., Ohtaki, K., Kodama, Y., Lucas, J. & Gray, J., Jan 1 1992, In : Journal of radiation research. 33, p. 206-214 9 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

FISH probes for mouse chromosome identification

Shi, Y. P., Mohapatra, G., Miller, J., Hanahan, D., Lander, E., Gold, P., Pinkel, D. & Gray, J., Oct 1 1997, In : Genomics. 45, 1, p. 42-47 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Flow cytometric analysis of bromodeoxyuridine substituted cells stained with 33258 Hoechst

Latt, S. A., George, Y. S. & Gray, J. W., Jan 1 1977, In : Journal of Histochemistry and Cytochemistry. 25, 7, p. 927-934 8 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Flow cytometric characterization of a Chinese hamster x man hybrid cell line retaining the human Y chromosome

Cremer, C., Gray, J. W. & Ropers, H. H., May 1 1982, In : Human genetics. 60, 3, p. 262-266 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine.

Dolbeare, F., Gratzner, H., Pallavicini, M. G. & Gray, J. W., Sep 1983, In : Proceedings of the National Academy of Sciences of the United States of America. 80, 18, p. 5573-5577 5 p.

Research output: Contribution to journalArticle

Open Access
886 Scopus citations

Flow cytometry and cell kinetics: relation to cancer therapy

Gray, J. W., Jan 1 1981, In : Acta Pathologica et Microbiologica Scandinavica - Section A Pathology. 89, Suppl.274, p. 485-491 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Flow cytometry of isolated nuclei prepared from gL rat brain tumor

Hoshino, T., Gray, J. W. & Nomura, K., Jan 1 1979, In : Laboratory Investigation. 41, 1, p. 72-76 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Flow cytometry of mammalian sperm progress in DNA and morphology measurement

Pinkel, D., Dean, P., Lake, S., Peters, D., Mendelsohn, M., Gray, J., Van Dilla, M. & Gledhill, B., Jan 1 1979, In : Unknown Journal. 27, 1, p. 353-358 6 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Flow karyotyping: current status and potential development

Van Dilla, M. A., Carrano, A. V. & Gray, J. W., Jan 1 1976, In : LAWRENCE LIVERMORE LAB., U.CALIF.. p. 145-164 20 p.

Research output: Contribution to journalArticle

2 Scopus citations

Flow karyotyping and sorting of human chromosomes

Gray, J. W., Lucas, J., Peters, D., Pinkel, D., Trask, B., van den Engh, G. & Van Dilla, M., 1986, In : Cold Spring Harbor symposia on quantitative biology. 51, 1, p. 141-149 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Flow microfluorometric analysis of nuclei isolated from brain and brain tumors

Hoshino, T., Wheeler, K. T., Gray, J. W. & Nomura, K., Jan 1 1976, In : Cancer Treatment Reports. 60, 12, 1 p.

Research output: Contribution to journalArticle

Flow microfluorometric analysis of sperm DNA content: Effect of cell shape on the fluorescence distribution

Gledhill, B. L., Lake, S., Steinmetz, L. L., Gray, J. W., Crawford, J. R., Dean, P. N. & Van Dilla, M. A., Mar 1976, In : Journal of Cellular Physiology. 87, 3, p. 367-375 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

Fluorescence-activated Cell Sorting Analysis of the Induction and Expression of Acute Thermal Tolerance within the Cell Cycle

Rice, G. C., Dewey, W. C., Gray, J. W. & Dean, P. N., Jun 1 1984, In : Cancer Research. 44, 6, p. 2368-2376 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Fluorescence in situ hybridization to interphase cell nuclei in suspension allows flow cytometric analysis of chromosome content and microscopic analysis of nuclear organization

Trask, B., van den Engh, G., Pinkel, D., Mullikin, J., Waldman, F., van Dekken, H. & Gray, J., Mar 1 1988, In : Human genetics. 78, 3, p. 251-259 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Fluorescence in situ hybridization with human chromosome-specific libraries: Detection of trisomy 21 and translocations of chromosome 4

Pinkel, D., Landegent, J., Collins, C., Fuscoe, J., Segraves, R., Lucas, J. & Gray, J., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 23, p. 9138-9142 5 p.

Research output: Contribution to journalArticle

Open Access
1144 Scopus citations

Fluorescent nucleic add hybridization methods

Pinkel, D., Gray, J., Segraves, R., Waldman, F., Trask, B., Yu, L. C., Eastmond, D. & Dean, P., Jun 13 1989, In : Proceedings of SPIE - The International Society for Optical Engineering. 1063, p. 123-132 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

Fu, X., Jeselsohn, R., Pereira, R., Hollingsworth, E. F., Creighton, C. J., Li, F., Shea, M., Nardone, A., De Angelis, C., Heiser, L. M., Anur, P., Wang, N., Grasso, C. S., Spellman, P. T., Griffith, O. L., Tsimelzon, A., Gutierrez, C., Huang, S., Edwards, D. P., Trivedi, M. V. & 7 others, Rimawi, M. F., Lopez-Terrada, D., Hilsenbeck, S. G., Gray, J. W., Brown, M., Osborne, C. K. & Schiff, R., Oct 25 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 43, p. E6600-E6609

Research output: Contribution to journalArticle

47 Scopus citations

Frequent Novel DNA Copy Number Increase in Squamous Cell Head and Neck Tumors

Brzoska, P. M., Levin, N. A., Fu, K. K., Kaplan, M. J., Singer, M. I., Gray, J. W. & Christman, M. F., Jul 15 1995, In : Cancer Research. 55, 14, p. 3055-3059 5 p.

Research output: Contribution to journalArticle

97 Scopus citations