• 65500 Citations
  • 111 h-Index
1971 …2020
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1971 2020

10 Citations (Scopus)
Polyamines
Cell Cycle
G2 Phase
Cell Division
Putrescine
151 Citations (Scopus)

Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

Creighton, C. J., Fu, X., Hennessy, B. T., Casa, A. J., Zhang, Y., Gonzalez-Angulo, A. M., Lluch, A., Gray, J., Brown, P. H., Hilsenbeck, S. G., Osborne, C. K., Mills, G., Lee, A. V. & Schiff, R., Jun 22 2010, In : Breast Cancer Research. 12, 3, R40.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Estrogen Receptors
Proteomics
Breast Neoplasms
Growth Factor Receptors
39 Citations (Scopus)

Purification of the chromosomes of the Indian muntjac by flow sorting

Carrano, A. V., Gray, J., Moore, D. H., Minkler, J. L., Mayall, B. H., van Dilla, M. A. & Mendelsohn, M. L., 1976, In : Journal of Histochemistry and Cytochemistry. 24, 1, p. 348-354 7 p.

Research output: Contribution to journalArticle

Muntjacs
Chromosomes
Centromere
DNA
X Chromosome
144 Citations (Scopus)

Qdot nanobarcodes for multiplexed gene expression analysis

Eastman, P. S., Ruan, W., Doctolero, M., Nuttall, R., De Feo, G., Park, J. S., Chu, J. S. F., Cooke, P., Gray, J., Li, S. & Chen, F. F., May 2006, In : Nano Letters. 6, 5, p. 1059-1064 6 p.

Research output: Contribution to journalArticle

gene expression
Microarrays
Gene expression
Complementary RNA
Semiconductor quantum dots
19 Citations (Scopus)

Quantification of mammalian sperm morphology by slit-scan flow cytometry

Benaron, D. A., Gray, J., Gledhill, B. L., Lake, S., Wyrobek, A. J. & Young, I. T., 1982, Cytometry. 5 ed. Vol. 2. p. 344-349 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sperm Head
Species Specificity
Cricetinae
Spermatozoa
Testis
6 Citations (Scopus)

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

Hafner, M., Heiser, L., Williams, E. H., Niepel, M., Wang, N. J., Korkola, J., Gray, J. & Sorger, P. K., Nov 7 2017, In : Scientific data. 4, 170166.

Research output: Contribution to journalArticle

Breast Cancer
quantification
Quantification
Cancer
Drugs
31 Citations (Scopus)

Quantification of the DNA content of structurally abnormal X chromosomes and X chromosome aneuploidy using high resolution bivariate flow karyotyping

Trask, B., Van den Engh, G., Nussbaum, R., Schwartz, C. & Gray, J., 1990, In : Cytometry. 11, 1, p. 184-195 12 p.

Research output: Contribution to journalArticle

Karyotyping
X Chromosome
Aneuploidy
Cytogenetics
Karyotype
9 Citations (Scopus)

Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy

Zhang, Y., Huang, T., Jorgens, D., Nickerson, A., Lin, L. J., Pelz, J., Gray, J., Lopez, C. & Nan, X., May 1 2017, In : PLoS One. 12, 5, e0176839.

Research output: Contribution to journalArticle

Electron Scanning Microscopy
Electron microscopy
Microscopy
microscopy
Drying
2 Citations (Scopus)

Quantitative, in situ analysis of mRNAs and proteins with subcellular resolution

Kwon, S., Chin, K-Y., Nederlof, M. & Gray, J., Dec 1 2017, In : Scientific Reports. 7, 1, 16459.

Research output: Contribution to journalArticle

Messenger RNA
Breast Neoplasms
Fluorescent Antibody Technique
Proteins
RNA
78 Citations (Scopus)

Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival

Jain, A. N., Chin, K-Y., Børresen-Dale, A. L., Erikstein, B. K., Lonning, P. E., Kaaresen, R. & Gray, J., 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 14, p. 7952-7957 6 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Comparative Genomic Hybridization
Survival
Genes
Datasets
7 Citations (Scopus)

Quantitative analysis of histological tissue image based on cytological profiles and spatial statistics

Chang, Y. H., Thibault, G., Azimi, V., Johnson, B., Jorgens, D., Link, J., Margolin, A. & Gray, J., Oct 13 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., Vol. 2016-October. p. 1175-1178 4 p. 7590914

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Statistics
Tissue
Chemical analysis
Spatial Analysis
Hematoxylin
19 Citations (Scopus)

Quantitative analysis of the cytokinetic response of KHT tumors in vivo to 1-β-D-arabinofuranosylcytosine

Pallavicini, M. G., Gray, J. & Folstad, L. J., 1982, In : Cancer Research. 42, 8, p. 3125-3131 7 p.

Research output: Contribution to journalArticle

Cytarabine
Neoplasms
S Phase
Thymidine
Cell Survival
20 Citations (Scopus)

Quantitative cytokinetics: Cellular response to cell cycle specific agents

Gray, J., 1983, In : Pharmacology and Therapeutics. 22, 2, p. 163-197 35 p.

Research output: Contribution to journalArticle

Drug Administration Schedule
Biological Models
DNA Replication
Mitosis
Antineoplastic Agents
92 Citations (Scopus)

Quantitative DNA fiber mapping

Weler, H. U. G., Wang, L., Mullikin, J. C., Zhu, Y., Cheng, J. F., Greulich, K. M., Bensimon, A. & Gray, J., Oct 1995, In : Human Molecular Genetics. 4, 10, p. 1903-1910 8 p.

Research output: Contribution to journalArticle

Clone
DNA
Clone Cells
Fiber
Fibers
91 Citations (Scopus)

Quantitative karyotyping of human chromosomes by dual beam flow cytometry

Langlois, R. G., Yu, L. C., Gray, J. & Carrano, A. V., 1982, In : Proceedings of the National Academy of Sciences of the United States of America. 79, 24 I, p. 7876-7880 5 p.

Research output: Contribution to journalArticle

Karyotyping
Human Chromosomes
Flow Cytometry
Chromosomes
Karyotype
489 Citations (Scopus)

Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene

Albertson, D. G., Ylstra, B., Segraves, R., Collins, C., Dairkee, S. H., Kowbel, D., Kuo, W. L., Gray, J. & Pinkel, D., Jun 2000, In : Nature Genetics. 25, 2, p. 144-146 3 p.

Research output: Contribution to journalArticle

Physical Chromosome Mapping
Steroid Hydroxylases
Chromosomes, Human, Pair 20
Nucleic Acid Hybridization
Trans-Activators
255 Citations (Scopus)

Quantitative mRNA expression analysis from formalin-fixed, paraffin-embedded tissues using 5′ nuclease quantitative reverse transcription-polymerase chain reaction

Godfrey, T. E., Kim, S. H., Chavira, M., Ruff, D. W., Warren, R. S., Gray, J. & Jensen, R. H., May 2000, In : Journal of Molecular Diagnostics. 2, 2, p. 84-91 8 p.

Research output: Contribution to journalArticle

Paraffin
Formaldehyde
Reverse Transcription
Polymerase Chain Reaction
Messenger RNA
101 Citations (Scopus)

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis

Tsujikawa, T., Kumar, S., Borkar, R. N., Azimi, V., Thibault, G., Chang, Y. H., Balter, A., Kawashima, R., Choe, G., Sauer, D., El Rassi, E., Clayburgh, D., Kulesz-Martin, M., Lutz, E. R., Zheng, L., Jaffee, E. M., Leyshock, P., Margolin, A., Mori, M. T., Gray, J. & 2 others, Flint, P. & Coussens, L., Apr 4 2017, In : Cell Reports. 19, 1, p. 203-217 15 p.

Research output: Contribution to journalArticle

Tumors
Immunohistochemistry
Tissue
Biomarkers
Papillomaviridae
55 Citations (Scopus)

Quantum dots-based reverse phase protein microarray

Shingyoji, M., Gerion, D., Pinkel, D., Gray, J. & Chen, F., Sep 15 2005, In : Talanta. 67, 3, p. 472-478 7 p.

Research output: Contribution to journalArticle

Quantum Dots
Protein Array Analysis
Microarrays
Semiconductor quantum dots
Horseradish Peroxidase
46 Citations (Scopus)

Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress

Cheng, K. W., Agarwal, R., Mitra, S., Lee, J. S., Carey, M., Gray, J. & Mills, G., Feb 2012, In : EMBO Molecular Medicine. 4, 2, p. 125-141 17 p.

Research output: Contribution to journalArticle

Glycogen
Energy Metabolism
Adenosine Triphosphate
Neoplasms
Autophagy
131 Citations (Scopus)

Radiation-induced chromosome aberrations analysed by fluorescence in situ hybridization with a triple combination of composite whole chromosome-specific DNA probes

Schmid, E., Zitzelsberger, H., Braselmann, H., Gray, J. & Bauchinger, M., 1992, In : International Journal of Radiation Biology. 62, 6, p. 673-678 6 p.

Research output: Contribution to journalArticle

chromosome aberrations
chromosomes
DNA probes
DNA Probes
Chromosomes
12 Citations (Scopus)

Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities

Langland, G. T., Yannone, S. M., Langland, R. A., Nakao, A., Guan, Y., Long, S. B. T., Vonguyen, L., Chen, D. J., Gray, J. & Chen, F., Apr 2010, In : Oncology Reports. 23, 4, p. 1021-1026 6 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Radiation Tolerance
Ovarian Neoplasms
Cell Line
Radiation
10 Citations (Scopus)

Rapid cell cycle analysis. II. Phase durations and dispersions from computer analysis of RC curves.

Gray, J., Bogart, E., Gavel, D. T., George, Y. S. & Moore, D. H., Sep 1983, In : Cell and Tissue Kinetics. 16, 5, p. 457-471 15 p.

Research output: Contribution to journalArticle

Radioactivity
Cell Cycle
G2 Phase
S Phase
Cell Division

Rapid cell cycle analysis by measurement of the radioactivity per cell in a narrow window in S phase (RCS(i))

Gray, J., Carver, J. H., George, Y. S. & Mendelsohn, M. L., 1977, In : Cell and Tissue Kinetics. 10, 2, p. 97-109 13 p.

Research output: Contribution to journalArticle

S Phase
Radioactivity
Cell Cycle
Mitosis
DNA
33 Citations (Scopus)

RAPID CELL CYCLE ANALYSIS BY MEASUREMENT OF THE RADIOACTIVITY PER CELL IN A NARROW WINDOW IN S PHASE (RCSi)

Gray, J., Carver, J. H., George, Y. S. & Mendelsohn, M. L., 1977, In : Cell Proliferation. 10, 2, p. 97-109 13 p.

Research output: Contribution to journalArticle

S Phase
Radioactivity
Cell Cycle
Mitosis
DNA
173 Citations (Scopus)

Rapid human chromosome aberration analysis using fluorescence in situ hybridization

Lucas, J. N., Tenjin, T., Straume, T., Pinkel, D., Moore, D., Litt, M. & Gray, J., 1989, In : International Journal of Radiation Biology. 56, 1, p. 35-44 10 p.

Research output: Contribution to journalArticle

chromosome aberrations
Lymphocytes
Human Chromosomes
Metaphase
Chromosomes
1 Citation (Scopus)

Rapid isolation of metaphase chromosomes after stabilization by a psoralen

Aten, J. A., Yu, L., Lucas, J. N. & Gray, J., 1980, In : Basic and Applied Histochemistry. 24, 4, p. 341 1 p.

Research output: Contribution to journalArticle

Ficusin
Metaphase
Chromosomes
422 Citations (Scopus)

Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation

Lucas, J. N., Awa, A., Straume, T., Poggensee, M., Kodama, Y., Nakano, M., Ohtaki, K., Weier, H. U., Pinkel, D., Gray, J. & Littlefield, G., 1992, In : International Journal of Radiation Biology. 62, 1, p. 53-63 11 p.

Research output: Contribution to journalArticle

Ionizing radiation
Ionizing Radiation
ionizing radiation
Fluorescence In Situ Hybridization
Fluorescence
106 Citations (Scopus)

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway

Nan, X., Tamgüney, T. M., Collisson, E. A., Lin, L. J., Pitt, C., Galeas, J., Lewis, S., Gray, J., McCormick, F. & Chu, S., Jun 30 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 26, p. 7996-8001 6 p.

Research output: Contribution to journalArticle

Guanosine Triphosphate
Mitogen-Activated Protein Kinases
Sarcoma
Dimerization
Cell Membrane
21 Citations (Scopus)

Rates of incorporation of radioactive molecules during the cell cycle

Gray, J., Pallavicini, M. G., George, Y. S., Groppi, V., Look, M. & Dean, P. N., 1981, In : Journal of Cellular Physiology. 108, 2, p. 135-144 10 p.

Research output: Contribution to journalArticle

S Phase
Cell Cycle
Cells
Molecules
Tumors
120 Citations (Scopus)

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Lovci, M. T., Ghanem, D., Marr, H., Arnold, J., Gee, S., Parra, M., Liang, T. Y., Stark, T. J., Gehman, L. T., Hoon, S., Massirer, K. B., Pratt, G. A., Black, D. L., Gray, J., Conboy, J. G. & Yeo, G. W., Dec 2013, In : Nature Structural and Molecular Biology. 20, 12, p. 1434-1442 9 p.

Research output: Contribution to journalArticle

Alternative Splicing
RNA
Exons
Messenger RNA
Proteins
48 Citations (Scopus)

Reconciliation of classification systems defining molecular subtypes of colorectal cancer: Interrelationships and clinical implications

Sadanandam, A., Wang, X., De Sousa E Melo, F., Gray, J., Vermeulen, L., Hanahan, D. & Medema, J. P., Feb 1 2014, In : Cell Cycle. 13, 3, p. 353-357 5 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Gene Expression
Therapeutics
580 Citations (Scopus)

Reconstruction of functionally normal and malignant human breast tissues in mice

Kuperwasser, C., Chavarria, T., Wu, M., Magrane, G., Gray, J., Carey, L., Richardson, A. & Weinberg, R. A., Apr 6 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 14, p. 4966-4971 6 p.

Research output: Contribution to journalArticle

Breast
Morphogenesis
Carcinogenesis
Epithelial Cells
Medical Genetics

Reconstruction of Gene Regulatory Networks Based on Repairing Sparse Low-Rank Matrices

Chang, Y. H., Dobbe, R., Bhushan, P., Gray, J. & Tomlin, C. J., Jul 1 2016, In : IEEE/ACM Transactions on Computational Biology and Bioinformatics. 13, 4, p. 767-777 11 p., 7182286.

Research output: Contribution to journalArticle

Low-rank Matrices
Gene Regulatory Networks
Gene Regulatory Network
Sparse matrix
Genes
Cytarabine
Cell Survival
Radiation
S Phase
Maintenance
15 Citations (Scopus)

Relationship of c-myc gene copy number and gene expression: Cellular effects of elevated c-myc protein

Pallavicini, M. G., Rosette, C., Reitsma, M., Deteresa, P. S. & Gray, J., 1990, In : Journal of Cellular Physiology. 143, 2, p. 372-380 9 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-myc
myc Genes
Gene Dosage
Gene expression
Genes
4 Citations (Scopus)

Replication kinetics of Chinese hamster chromosomes as revealed by bivariate flow karyotyping

Cremer, C. & Gray, J., 1983, Cytometry. 4 ed. Vol. 3. p. 282-286 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Reply to Colorectal cancer classification based on gene expression is not associated with FOLFIRI response

Sadanandam, A., Gray, J. & Hanahan, D., Nov 1 2014, In : Nature Medicine. 20, 11, p. 1231-1232 2 p.

Research output: Contribution to journalArticle

Gene expression
1 Citation (Scopus)

Response to neoadjuvant therapy for breast cancer by magnetic resonance imaging type, estrogen receptor status, grade, and comparative genomic hybridization

Esserman, L. J., Sudilovsky, D., Kuo, W. I., Gray, J. & Hylton, N., 2001, In : Breast Cancer Research and Treatment. 69, 3, p. 245 1 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Comparative Genomic Hybridization
Estrogen Receptors
Magnetic Resonance Imaging
Breast Neoplasms
6 Citations (Scopus)

Restoration of Profiles from Slit-Scan Flow Cytometry

Norgren, R. M., Gray, J. & Young, I. T., 1982, In : IEEE Transactions on Biomedical Engineering. BME-29, 2, p. 101-106 6 p.

Research output: Contribution to journalArticle

Flow cytometry
Chromosomes
Restoration
Laser beams
Fourier analysis
229 Citations (Scopus)

Restriction of receptor movement alters cellular response: Physical force sensing by EphA2

Salaita, K., Nair, P. M., Petit, R. S., Neve, R. M., Das, D., Gray, J. & Groves, J. T., Mar 12 2010, In : Science. 327, 5971, p. 1380-1385 6 p.

Research output: Contribution to journalArticle

Ephrin-A1
Ligands
EphA2 Receptor
Disintegrins
Architectural Accessibility
2 Citations (Scopus)

Retrieving common dynamics of gene regulatory networks under various perturbations

Chang, Y. H., Dobbe, R., Bhushan, P., Gray, J. & Tomlin, C. J., Feb 8 2016, Proceedings of the IEEE Conference on Decision and Control. Institute of Electrical and Electronics Engineers Inc., Vol. 2016-February. p. 2531-2536 6 p. 7402597

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gene Regulatory Network
Genes
Perturbation
Proteomics
Graph in graph theory
42 Citations (Scopus)

Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature

Tutt, A., Wang, A., Rowland, C., Gillett, C., Lau, K., Chew, K., Dai, H., Kwok, S., Ryder, K., Shu, H., Springall, R., Cane, P., McCallie, B., Kam-Morgan, L., Anderson, S., Buerger, H., Gray, J., Bennington, J., Esserman, L., Hastie, T. & 4 others, Broder, S., Sninsky, J., Brandt, B. & Waldman, F., Nov 21 2008, In : BMC Cancer. 8, 339.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Neoplasm Metastasis
Polymerase Chain Reaction
Survival
1 Citation (Scopus)

Robust Cell Detection and Segmentation for Image Cytometry Reveal Th17 Cell Heterogeneity

Tsujikawa, T., Thibault, G., Azimi, V., Sivagnanam, S., Banik, G., Means, C., Kawashima, R., Clayburgh, D., Gray, J., Coussens, L. & Chang, Y. H., Jan 1 2019, In : Cytometry Part A.

Research output: Contribution to journalArticle

Image Cytometry
Th17 Cells
Papillomaviridae
Immunohistochemistry
Biomarkers

Segmentation of Cell Nuclei from Confocal Microscope Images of Thick Tissue Samples

Ortiz de Solorzano, C., Sarti, A., Rodriguez, E. G., Jones, A., Sudar, D., Pinkel, D., Gray, J., Malladi, R. & Lockett, S. J., 1998, Proceedings of the Joint Conference on Information Sciences. Li, K., Pan, Y., Wang, P. P., Al-Dhelaan, A., Da Cheng, H., Pan, Y., Wang, P. P., Li, K., Al-Dhelaan, A. & Da Cheng, H. (eds.). Vol. 4. p. 187-190 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hough transforms
Microscopes
Visualization
Cells
Tissue
121 Citations (Scopus)

Segmentation of confocal microscope images of cell nuclei in thick tissue sections

Ortiz De Solórzano, C., García Rodriguez, E., Jones, A., Pinkel, D., Gray, J., Sudar, D. & Lockett, S. J., 1999, In : Journal of Microscopy. 193, 3, p. 212-226 15 p.

Research output: Contribution to journalArticle

Cell Nucleus
Microscopes
microscopes
Cells
Tissue
9 Citations (Scopus)

Semiautomated DNA probe mapping using digital imaging microscopy: I. System development

Mascio, L. N., Verbeek, P. W., Sudar, D., Kuo, W. L. & Gray, J., 1995, In : Cytometry. 19, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

DNA Probes
Microscopy
Chromosomes
Metaphase
Human Chromosomes
20 Citations (Scopus)

Semiautomated DNA probe mapping using digital imaging microscopy: II. System performance

Sakamoto, M., Pinkel, D., Mascio, L., Sudar, D., Peters, D., Kuo, W. L., Yamakawa, K., Nakamura, Y., Drabkin, H., Jericevic, Z., Smith, L. & Gray, J., 1995, In : Cytometry. 19, 1, p. 60-69 10 p.

Research output: Contribution to journalArticle

Cosmids
DNA Probes
Bacteriophages
Microscopy
Chromosomes
21 Citations (Scopus)

Separation and analysis of human chromosomes by combined velocity sedimentation and flow sorting applying single- and dual-laser flow cytometry

Collard, J. G., Philippus, E., Tulp, A., Lebo, R. V. & Gray, J., 1984, Cytometry. 1 ed. Vol. 5. p. 9-19 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cell Fractionation
Density Gradient Centrifugation
Human Chromosomes
Metaphase
Flow Cytometry
3 Citations (Scopus)

SHIFT: Speedy histopathological-To-immunofluorescent translation of whole slide images using conditional generative adversarial networks

Burlingame, E. A., Margolin, A., Gray, J. & Chang, Y. H., Jan 1 2018, Medical Imaging 2018: Digital Pathology. SPIE, Vol. 10581. 1058105

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hematoxylin
Eosine Yellowish-(YS)
chutes
Coloring Agents
Imaging techniques