• 65064 Citations
  • 110 h-Index
1971 …2020
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Research Output 1971 2020

1994
128 Citations (Scopus)

Statement on Use of DNA Testing for Presymptomatic Identification of Cancer Risk

Collins, F. S., Benjamin, L. J., Botstein, D., Cox, J. R., Davidson, N., Gray, J., Housman, D. E., Holtzman, N., Jamison, K. R., Rothstein, R., Smith, D. C., Smith, L. M., Spence, M. A. & Tilghman, S. M., Mar 9 1994, In : JAMA - Journal of the American Medical Association. 271, 10, p. 785 1 p.

Research output: Contribution to journalArticle

Inborn Genetic Diseases
Genetic Testing
Advisory Committees
Oncogenes
DNA
61 Citations (Scopus)

Thick-section fluorescence in situ hybridization on formalin-fixed, paraffin-embedded archival tissue provides a histogenetic profile

Thompson, C. T., LeBoit, P. E., Nederlof, P. M. & Gray, J., Feb 1994, In : American Journal of Pathology. 144, 2, p. 237-243 7 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Paraffin
Formaldehyde
Gene Dosage
DNA Probes
1993
4 Citations (Scopus)

Application of confocal laser scanning microscope on fluorescence in situ hybridization (FISH)

Matsuta, M., Matsuta, M., Sasaki, K., Hariu, H., Nishiya, I., Katou, M., Kallioniemi, A., Weier, H. U. & Gray, J., 1993, In : Acta Histochemica et Cytochemica. 26, 5, p. 415-421 7 p.

Research output: Contribution to journalArticle

DNA sequences
Chromosomes
Fluorescence In Situ Hybridization
Chromosomes, Human, Pair 6
Lasers
7 Citations (Scopus)

Application of x rays to the analysis of DNA packaging in mammalian sperm

Balhorn, R., Corzett, M., Allen, M. J., Lee, C., Barbee, T. W., Koch, J. A., MacGowan, B. J., Matthews, D. L., Mrowka, S. J., Trebes, J. E., McNulty, I., Da Silva, L. B., Gray, J., Anderson, E. H., Kern, D. & Attwood, D. T., 1993, Proceedings of SPIE - The International Society for Optical Engineering. Publ by Int Soc for Optical Engineering, Vol. 1741. p. 374-385 12 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

packaging
Packaging
DNA
deoxyribonucleic acid
X rays
12 Citations (Scopus)

Chromosomal Reassignment: YACs Containing Both YES1 and Thymidylate Synthase Map to the Short Arm of Chromosome 18

Silverman, G. A., Kuo, W. L., Taillon-Miller, P. & Gray, J., Feb 1993, In : Genomics. 15, 2, p. 442-445 4 p.

Research output: Contribution to journalArticle

Yeast Artificial Chromosomes
Chromosomes, Human, Pair 18
Thymidylate Synthase
Genes
Proto-Oncogenes
6 Citations (Scopus)

Cloning and Characterization of EagI YACs from Human Chromosome 21

Gingrich, J. C., Lowry, S. R., Kuo, W. L., Gray, J., Smith, C. L. & Cantori, C. R., Jan 1993, In : Genomics. 15, 1, p. 228-230 3 p.

Research output: Contribution to journalArticle

Yeast Artificial Chromosomes
Chromosomes, Human, Pair 21
Human Chromosomes
Organism Cloning
Hybrid Cells
202 Citations (Scopus)

Comparative genomic hybridization: A rapid new method for detecting and mapping DNA amplification in tumors

Kallioniemi, O. P., Kallioniemi, A., Sudar, D., Rutovitz, D., Gray, J., Waldman, F. & Pinkel, D., 1993, In : Seminars in Cancer Biology. 4, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

Comparative Genomic Hybridization
DNA
Neoplasms
Metaphase
Fluorescent Dyes
20 Citations (Scopus)
Comparative Genomic Hybridization
Fluorescence In Situ Hybridization
Cytogenetics
Neoplasms
Chromosomes
3 Citations (Scopus)

Derivative domain fitting: A new method for resolving a mixture of normal distributions in the presence of a contaminating background

Moore, D. H. & Gray, J., 1993, In : Cytometry. 14, 5, p. 510-518 9 p.

Research output: Contribution to journalArticle

Normal Distribution
Least-Squares Analysis
18 Citations (Scopus)
Satellite DNA
Chromosomes, Human, Pair 10
DNA Primers
Cell Separation
Interphase

Imaging microscopy with x-ray lasers at LLNL

Da Silva, L. B., Trebes, J. E., Mrowka, S. J., MacGowan, B. J., Koch, J. A., Matthews, D. L., Barbee, T. W., Balhorn, R., Gray, J., Anderson, E. H., Kern, D. & Attwood, D. T., 1993, Proceedings of SPIE - The International Society for Optical Engineering. Publ by Int Soc for Optical Engineering, Vol. 1741. p. 154-159 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

x ray lasers
Microscopic examination
microscopy
Imaging techniques
X rays
59 Citations (Scopus)

Libraries for each human chromosome, constructed from sorter-enriched chromosomes by using linker-adaptor PCR

Vooijs, M., Yu, L. C., Tkachuk, D., Pinkel, D., Johnson, D. & Gray, J., Mar 1993, In : American Journal of Human Genetics. 52, 3, p. 586-597 12 p.

Research output: Contribution to journalArticle

Human Chromosomes
Libraries
Chromosomes
Polymerase Chain Reaction
Oligonucleotides
4 Citations (Scopus)

Molecular cytogenetic analysis of human tumors

Gray, J., 1993, In : Annals of the New York Academy of Sciences. 677, p. 194-198 5 p.

Research output: Contribution to journalArticle

Flow cytometry
Cytogenetic Analysis
Fluorescence microscopy
Tumor Suppressor Genes
Oncogenes
4 Citations (Scopus)

Molecular cytogenetics: Solid tumors and leukemia

Gray, J. & Pallavicini, M. G., 1993, In : Blood Cells. 19, 3, p. 677-683 7 p.

Research output: Contribution to journalArticle

Cytogenetics
Leukemia
Molecular Evolution
Neoplasms
Inborn Genetic Diseases
1992
43 Citations (Scopus)
Satellite DNA
Chromosomes, Human, Pair 21
Ploidies
Interphase
DNA Probes
2728 Citations (Scopus)

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

Kallioniemi, A., Kallioniemi, O. P., Sudar, D., Rutovitz, D., Gray, J., Waldman, F. & Pinkel, D., Oct 30 1992, In : Science. 258, 5083, p. 818-821 4 p.

Research output: Contribution to journalArticle

Comparative Genomic Hybridization
Cytogenetic Analysis
Fluorescent Dyes
Chromosomes
DNA
14 Citations (Scopus)

Construction and characterization of a yeast artificial chromosome library containing 1.5 equivalents of human chromosome 21

Potier, M. C., Kuo, W. L., Dutriaux, A., Gray, J. & Goedert, M., 1992, In : Genomics. 14, 2, p. 481-483 3 p.

Research output: Contribution to journalArticle

Yeast Artificial Chromosomes
Chromosomes, Human, Pair 21
Human Chromosomes
Yeasts
Libraries
107 Citations (Scopus)

Deletion of chromosome 17p loci in breast cancer cells detected by fluorescence in situ hybridization

Matsumura, K., Kallioniemi, A., Kallioniemi, O., Chen, L., Smith, H. S., Pinkel, D., Gray, J. & Waldman, F. M., Jun 15 1992, In : Cancer Research. 52, 12, p. 3474-3477 4 p.

Research output: Contribution to journalArticle

Chromosome Deletion
Loss of Heterozygosity
Fluorescence In Situ Hybridization
Breast Neoplasms
Centromere
45 Citations (Scopus)

Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization

Kallioniemi, A., Kallioniemi, O. P., Waidman, F. M., Chen, L. C., Yu, L. C., Fung, Y. K. T., Smith, H. S., Pinkel, D. & Gray, J., 1992, In : Cytogenetic and Genome Research. 60, 3-4, p. 190-193 4 p.

Research output: Contribution to journalArticle

Retinoblastoma Genes
Gene Dosage
Interphase
Metaphase
Fluorescence In Situ Hybridization
5 Citations (Scopus)

Differential staining of human and murine chromatin in situ by hybridization with species-specific satellite DNA probes

Weier, H. U. G., Zitzelsberger, H. F. & Gray, J., Feb 14 1992, In : Biochemical and Biophysical Research Communications. 182, 3, p. 1313-1319 7 p.

Research output: Contribution to journalArticle

Satellite DNA
DNA Probes
Chromatin
In Situ Hybridization
Chromosomes
435 Citations (Scopus)

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization

Kallioniemi, O. P., Kallioniemi, A., Kurisu, W., Thor, A., Chen, L. C., Smith, H. S., Waldman, F. M., Pinkel, D. & Gray, J., 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 12, p. 5321-5325 5 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Breast Neoplasms
Cell Line
Neoplasms
Chromosomes, Human, Pair 17
19 Citations (Scopus)

Factors that determine the in vivo dose-response relationship for stable chromosome aberrations in A-bomb survivors.

Awa, A. A., Nakano, M., Ohtaki, K., Kodama, Y., Lucas, J. & Gray, J., Mar 1992, In : Journal of Radiation Research. 33 Suppl, p. 206-214 9 p.

Research output: Contribution to journalArticle

Bombs
chromosome aberrations
Chromosome Aberrations
dose response
Survivors
21 Citations (Scopus)

Molecular cytogenetics: Diagnosis and prognostic assessment

Gray, J., Kallioniemi, A., Kallioniemi, O., Pallavicini, M., Waldman, F. & Pinkel, D., 1992, In : Current Opinion in Biotechnology. 3, 6, p. 623-631 9 p.

Research output: Contribution to journalArticle

Cytogenetics
Primed In Situ Labeling
Comparative Genomic Hybridization
Cytogenetic Analysis
Chromosomes
66 Citations (Scopus)

Molecular cytogenetics in human cancer diagnosis

Gray, J. & Pinkel, D., 1992, In : Cancer. 69, 6 SUPPL., p. 1536-1542 7 p.

Research output: Contribution to journalArticle

Cytogenetics
Chromosomes
Centromere
Gene Amplification
Interphase
131 Citations (Scopus)

Radiation-induced chromosome aberrations analysed by fluorescence in situ hybridization with a triple combination of composite whole chromosome-specific DNA probes

Schmid, E., Zitzelsberger, H., Braselmann, H., Gray, J. & Bauchinger, M., 1992, In : International Journal of Radiation Biology. 62, 6, p. 673-678 6 p.

Research output: Contribution to journalArticle

chromosome aberrations
chromosomes
DNA probes
DNA Probes
Chromosomes
422 Citations (Scopus)

Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation

Lucas, J. N., Awa, A., Straume, T., Poggensee, M., Kodama, Y., Nakano, M., Ohtaki, K., Weier, H. U., Pinkel, D., Gray, J. & Littlefield, G., 1992, In : International Journal of Radiation Biology. 62, 1, p. 53-63 11 p.

Research output: Contribution to journalArticle

Ionizing radiation
Ionizing Radiation
ionizing radiation
Fluorescence In Situ Hybridization
Fluorescence
23 Citations (Scopus)

Structural chromosome analysis by whole chromosome painting for assessment of radiation-induced genetic damage.

Gray, J., Lucas, J. N., Pinkel, D. & Awa, A., Mar 1992, In : Journal of Radiation Research. 33 Suppl, p. 80-86 7 p.

Research output: Contribution to journalArticle

Radiation Genetics
Chromosome Painting
Nucleic Acid Hybridization
chromosome aberrations
chromosomes
128 Citations (Scopus)

X-ray laser microscopy of rat sperm nuclei

Da Silva, L. B., Trebes, J. E., Balhorn, R., Mrowka, S., Anderson, E., Attwood, D. T., Barbee, T. W., Brase, J., Corzett, M., Gray, J., Koch, J. A., Lee, C., Kern, D., London, R. A., MacGowan, B. J., Matthews, D. L. & Stone, G., Oct 9 1992, In : Science. 258, 5080, p. 269-271 3 p.

Research output: Contribution to journalArticle

Confocal Microscopy
Spermatozoa
X-Rays
Chromatin
Microscopy
1991
19 Citations (Scopus)

Applications of fluorescence in situ hybridization in biological dosimetry and detection of disease-specific chromosome aberrations.

Gray, J., Lucas, J., Kallioniemi, O., Kallioniemi, A., Kuo, W. L., Straume, T., Tkachuk, D., Tenjin, T., Weier, H. U. & Pinkel, D., 1991, In : Progress in Clinical and Biological Research. 372, p. 399-411 13 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Chromosome Aberrations
Color
Human Genome Project
Genetic Translocation
38 Citations (Scopus)

Characterization of somatic cell hybrids by bivariate flow karyotyping and fluorescence in situ hybridization

Trask, B. J., van den Engh, G., Christensen, M., Massa, H. F., Gray, J. & Van Dilla, M., Mar 1991, In : Somatic Cell and Molecular Genetics. 17, 2, p. 117-136 20 p.

Research output: Contribution to journalArticle

Karyotyping
Hybrid Cells
Human Chromosomes
Fluorescence In Situ Hybridization
Karyotype
81 Citations (Scopus)

Clinical applications of fluorescence in situ hybridization

Tkachuk, D. C., Pinkel, D., Kuo, W. L., Weier, H. U. & Gray, J., 1991, In : Genetic Analysis: Biomolecular Engineering. 8, 2, p. 67-74 8 p.

Research output: Contribution to journalArticle

Chromosomes
Fluorescence In Situ Hybridization
Fluorescence
Aberrations
Inborn Genetic Diseases
212 Citations (Scopus)

Construction and characterization of plasmid libraries enriched in sequences from single human chromosomes

Collins, C., Kuo, W. L., Segraves, R., Fuscoe, J., Pinkel, D. & Gray, J., 1991, In : Genomics. 11, 4, p. 997-1006 10 p.

Research output: Contribution to journalArticle

Human Chromosomes
Libraries
Plasmids
Chromosomes
Fluorescence In Situ Hybridization
112 Citations (Scopus)

Detection of aneuploidy involving chromosomes 13, 18, or 21, by fluorescence in situ hybridization (FISH) to interphase and metaphase amniocytes

Kuo, W. L., Tenjin, H., Segraves, R., Pinkel, D., Golbus, M. S. & Gray, J., Jul 1991, In : American Journal of Human Genetics. 49, 1, p. 112-119 8 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 21
Interphase
Aneuploidy
15 Citations (Scopus)

Dicentric chromosome frequency analysis using slit-scan flow cytometry

Lucas, J. N., Mullikin, J. C. & Gray, J., 1991, In : Cytometry. 12, 4, p. 316-322 7 p.

Research output: Contribution to journalArticle

Flow Cytometry
Chromosomes
Demecolcine
Propidium
Chromosomes, Human, Pair 1
37 Citations (Scopus)

Labeling of the centromeric region on human chromosome 8 by in situ hybridization

Weier, H. U. G., Gray, J. & Kleine, H. D., Aug 1991, In : Human Genetics. 87, 4, p. 489-494 6 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 8
Human Chromosomes
In Situ Hybridization
DNA Probes
DNA
39 Citations (Scopus)
Fluoresceins
Molecular Sequence Data
Nucleic Acid Hybridization
Satellite DNA
Heterochromatin
12 Citations (Scopus)

Observations regarding DNA replication sites in human cells in vivo following infusions of iododeoxyuridine and bromodeoxyuridine

Raza, A., Miller, M. A., Mazewski, C., Sheikh, Y., Lampkin, B., Sawaya, R., Crone, K., Berger, T., Reising, J., Gray, J., Khan, S. & Preisler, H., 1991, In : Cell Proliferation. 24, 2, p. 113-126 14 p.

Research output: Contribution to journalArticle

Idoxuridine
Myeloid Leukemia
Gastrointestinal Neoplasms
Bromodeoxyuridine
Cell Nucleus
75 Citations (Scopus)

Two-color hybridization with high complexity chromosome-specific probes and a degenerate alpha satellite probe DNA allows unambiguous discrimination between symmetrical and asymmetrical translocations

Weier, H. U. G., Lucas, J. N., Poggensee, M., Segraves, R., Pinkel, D. & Gray, J., Jul 1991, In : Chromosoma. 100, 6, p. 371-376 6 p.

Research output: Contribution to journalArticle

Satellite DNA
Color
Chromosomes
Centromere
Sequence Homology
1990
22 Citations (Scopus)

Analytical approaches to detection and characterization of disease-linked chromosome aberrations

Gray, J., Kuo, W. L., Liang, J., Pinkel, D., Van den Engh Trask, G. B., Tkachuk, D., Waldman, F. & Westbrook, C., 1990, In : Bone Marrow Transplantation. 6, SUPPL. 1, p. 14-19 6 p.

Research output: Contribution to journalArticle

Chromosome Aberrations
Karyotyping
Chromosomes
Inborn Genetic Diseases
Cytogenetic Analysis
4 Citations (Scopus)

Automated detection of chromosome aberration using color information

Chen, C. H., Wang, Y., Mitra, S. K. & Gray, J., Mar 1 1990, In : Proceedings of SPIE - The International Society for Optical Engineering. 1192, p. 339-343 5 p.

Research output: Contribution to journalArticle

chromosome aberrations
chromosomes
Chromosomes
Aberrations
Aberration
27 Citations (Scopus)

Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine

Asai, A., Shibui, S., Barker, M., Vanderlaan, M., Gray, J. & Hoshino, T., 1990, In : Journal of Neurosurgery. 73, 2, p. 254-258 5 p.

Research output: Contribution to journalArticle

Idoxuridine
Bromodeoxyuridine
Brain Neoplasms
S Phase
Avidin
32 Citations (Scopus)

Chapter 21 Using Monoclonal Antibodies in Bromodeoxyuridine-DNA Analysis

Dolbeare, F., Kuo, W. L., Beisker, W., Vanderlaan, M. & Gray, J., 1990, In : Methods in Cell Biology. 33, C, p. 207-216 10 p.

Research output: Contribution to journalArticle

Nucleic Acid Denaturation
Data Display
Bromodeoxyuridine
Cricetulus
Cricetinae
44 Citations (Scopus)

Characterization and organization of DNA sequences adjacent to the human telomere associated repeat (TTAGGG)n

Weber, B., Collins, C., Robbins, C., Magenis, R. E., Delaney, A. D., Gray, J. & Hayden, M. R., Jun 11 1990, In : Nucleic Acids Research. 18, 11, p. 3353-3361 9 p.

Research output: Contribution to journalArticle

DNA sequences
Telomere
Human Chromosomes
Chromosomes
DNA Sequence
328 Citations (Scopus)

Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization

Tkachuk, D. C., Westbrook, C. A., Andreeff, M., Donlon, T. A., Cleary, M. L., Suryanarayan, K., Homge, M., Redner, A., Gray, J. & Pinkel, D., Oct 26 1990, In : Science. 250, 4980, p. 559-562 4 p.

Research output: Contribution to journalArticle

abl Genes
In Situ Hybridization
Leukemia
Chromosomes, Human, Pair 22
Philadelphia Chromosome
76 Citations (Scopus)

Effects of methotrexate on transfected DNA stability in mammalian cells

Pallavicini, M. G., Deteresa, P. S., Rosette, C., Gray, J. & Wurm, F. M., Jan 1990, In : Molecular and Cellular Biology. 10, 1, p. 401-404 4 p.

Research output: Contribution to journalArticle

Methotrexate
Cultured Cells
Tetrahydrofolate Dehydrogenase
DNA
31 Citations (Scopus)

Quantification of the DNA content of structurally abnormal X chromosomes and X chromosome aneuploidy using high resolution bivariate flow karyotyping

Trask, B., Van den Engh, G., Nussbaum, R., Schwartz, C. & Gray, J., 1990, In : Cytometry. 11, 1, p. 184-195 12 p.

Research output: Contribution to journalArticle

Karyotyping
X Chromosome
Aneuploidy
Cytogenetics
Karyotype
15 Citations (Scopus)

Relationship of c-myc gene copy number and gene expression: Cellular effects of elevated c-myc protein

Pallavicini, M. G., Rosette, C., Reitsma, M., Deteresa, P. S. & Gray, J., 1990, In : Journal of Cellular Physiology. 143, 2, p. 372-380 9 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-myc
myc Genes
Gene Dosage
Gene expression
Genes
37 Citations (Scopus)

Synthesis of Y chromosome-specific labeled DNA probes by in vitro DNA amplification

Weier, H. U. G., Segraves, R., Pinkel, D. & Gray, J., 1990, In : Journal of Histochemistry and Cytochemistry. 38, 3, p. 421-426 6 p.

Research output: Contribution to journalArticle

Y Chromosome
DNA Probes
DNA
DNA-Directed DNA Polymerase
Polymerase Chain Reaction
3 Citations (Scopus)

X-ray holography for sequencing DNA

Yorkey, T., Brase, J., Trebes, J., Lane, S. & Gray, J., 1990, Proceedings of SPIE - The International Society for Optical Engineering. Knauer, J. P. & Shenoy, G. K. (eds.). Publ by Int Soc for Optical Engineering, Vol. 1345. p. 255-259 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

sequencing
Holography
holography
DNA
deoxyribonucleic acid
2 Citations (Scopus)

X-ray holography for sequencing DNA

Yorkey, T., Brase, J., Trebes, J., Lane, S. & Gray, J., 1990, Proceedings of SPIE - The International Society for Optical Engineering. Javidi, B. (ed.). Publ by Int Soc for Optical Engineering, Vol. 1347. p. 474-478 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

sequencing
Holography
holography
DNA
deoxyribonucleic acid