• 66579 Citations
  • 112 h-Index
1971 …2020

Research output per year

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Research Output

2004

An Integrated View of Copy Number and Allelic Alterations in the Cancer Genome Using Single Nucleotide Polymorphism Arrays

Zhao, X., Li, C., Paez, J. G., Chin, K., Jänne, P. A., Chen, T. H., Girard, L., Minna, J., Christiani, D., Leo, C., Gray, J. W., Sellers, W. R. & Meyerson, M., May 1 2004, In : Cancer Research. 64, 9, p. 3060-3071 12 p.

Research output: Contribution to journalArticle

432 Scopus citations

Array comparative genomic hybridization with cyanin cis-platinum-labeled DNAs

Raap, A. K., Van Der Burg, M. J. M., Knijnenburg, J., Meershoek, E., Rosenberg, C., Gray, J. W., Wiegant, J., Hodgson, J. G. & Tanke, H. J., Jul 1 2004, In : BioTechniques. 37, 1, p. 130-134 5 p.

Research output: Contribution to journalArticle

14 Scopus citations
125 Scopus citations

Computational BAC Clone Contig Assembly for Comprehensive Genome Analysis

Lapuk, A., Volik, S., Vincent, R., Chin, K., Kuo, W. L., De Jong, P., Collins, C. & Gray, J. W., May 1 2004, In : Genes Chromosomes and Cancer. 40, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cytometry and Genetics

Cram, L. S., Gray, J. W. & Carter, N. P., Mar 1 2004, In : Cytometry Part A. 58, 1, p. 33-36 4 p.

Research output: Contribution to journalReview article

4 Scopus citations

Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma

Sonoda, I., Imoto, I., Inoue, J., Shibata, T., Shimada, Y., Chin, K., Imamura, M., Amagasa, T., Gray, J. W., Hirohashi, S. & Inazawa, J., Jun 1 2004, In : Cancer Research. 64, 11, p. 3741-3747 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

In situ analyses of genome instability in breast cancer

Chin, K., De Solorzano, C. O., Knowles, D., Jones, A., Chou, W., Rodriguez, E. G., Kuo, W. L., Ljung, B. M., Chew, K., Myambol, K., Miranda, M., Krig, S., Garbe, J., Stampfer, M., Yaswen, P., Gray, J. W. & Lockett, S. J., Sep 1 2004, In : Nature genetics. 36, 9, p. 984-988 5 p.

Research output: Contribution to journalArticle

289 Scopus citations

Oncogene Expression and Genetic Background Influence the Frequency of DNA Copy Number Abnormalities in Mouse Pancreatic Islet Cell Carcinomas

Hager, J. H., Hodgson, J. G., Fridlyand, J., Hariono, S., Gray, J. W. & Hanahan, D., Apr 1 2004, In : Cancer Research. 64, 7, p. 2406-2410 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability

Scacheri, P. C., Kennedy, A. L., Chin, K., Miller, M. T., Hodgson, J. G., Gray, J. W., Marx, S. J., Spiegel, A. M. & Collins, F. S., Oct 1 2004, In : Cancer Research. 64, 19, p. 7039-7044 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Reconstruction of functionally normal and malignant human breast tissues in mice

Kuperwasser, C., Chavarria, T., Wu, M., Magrane, G., Gray, J. W., Carey, L., Richardson, A. & Weinberg, R. A., Apr 6 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 14, p. 4966-4971 6 p.

Research output: Contribution to journalArticle

585 Scopus citations

TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines

Fan, W., Huang, X., Chen, C., Gray, J. & Huang, T., Aug 1 2004, In : Cancer Research. 64, 15, p. 5132-5139 8 p.

Research output: Contribution to journalArticle

86 Scopus citations

The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

Cheng, K. W., Lahad, J. P., Kuo, W. L., Lapuk, A., Yamada, K., Auersperg, N., Liu, J., Smith-McCune, K., Lu, K. H., Fishman, D., Gray, J. W. & Mills, G. B., Nov 1 2004, In : Nature medicine. 10, 11, p. 1251-1256 6 p.

Research output: Contribution to journalArticle

374 Scopus citations

The Role of p53 in Suppression of KSHV Cyclin-induced Lymphomagenesis

Verschuren, E. W., Hodgson, J. G., Gray, J. W., Kogan, S., Jones, N. & Evan, G. I., Jan 15 2004, In : Cancer Research. 64, 2, p. 581-589 9 p.

Research output: Contribution to journalArticle

68 Scopus citations
2003

Chromosome aberrations in solid tumors

Albertson, D. G., Collins, C., McCormick, F. & Gray, J. W., Aug 1 2003, In : Nature genetics. 34, 4, p. 369-376 8 p.

Research output: Contribution to journalReview article

567 Scopus citations

End-sequence profiling: Sequence-based analysis of aberrant genomes

Volik, S., Zhao, S., Chin, K., Brebner, J. H., Herndon, D. R., Tao, Q., Kowbel, D., Huang, G., Lapuk, A., Kuo, W. L., Magrane, G., De Jong, P., Gray, J. W. & Collins, C., Jun 24 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 13, p. 7696-7701 6 p.

Research output: Contribution to journalArticle

111 Scopus citations

Evidence emerges for early metastasis and parallel evolution of primary and metastatic tumors

Gray, J. W., Jul 1 2003, In : Cancer Cell. 4, 1, p. 4-6 3 p.

Research output: Contribution to journalReview article

79 Scopus citations

Genome amplification of chromosome 20 in breast cancer

Hodgson, J. G., Chin, K., Collins, C. & Gray, J. W., Apr 1 2003, In : Breast Cancer Research and Treatment. 78, 3, p. 337-345 9 p.

Research output: Contribution to journalReview article

79 Scopus citations

Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors

Hackett, C. S., Hodgson, J. G., Law, M. E., Fridlyand, J., Osoegawa, K., De Jong, P. J., Nowak, N. J., Pinkel, D., Albertson, D. G., Jain, A., Jenkins, R., Gray, J. W. & Weiss, W. A., Sep 1 2003, In : Cancer Research. 63, 17, p. 5266-5273 8 p.

Research output: Contribution to journalArticle

89 Scopus citations

Induction of tumors in mice by genomic hypomethylation

Gaudet, F., Hodgson, J. G., Eden, A., Jackson-Grusby, L., Dausman, J., Gray, J. W., Leonhardt, H. & Jaenisch, R., Apr 18 2003, In : Science. 300, 5618, p. 489-492 4 p.

Research output: Contribution to journalArticle

1108 Scopus citations

In Situ Quantification of Genomic Instability in Breast Cancer Progression

Ortiz De Solórzano, C., Chin, K., Gray, J. W. & Lockett, S. J., Dec 1 2003, In : Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 4, p. 3578-3581 4 p.

Research output: Contribution to journalConference article

Linking Molecular Diagnostics to Molecular Therapeutics: Targeting the PI3K Pathway in Breast Cancer

Mills, G. B., Kohn, E., Lu, Y., Eder, A., Fang, X., Wang, H., Bast, R. C., Gray, J., Jaffe, R. & Hortobagyi, G., Oct 2003, In : Seminars in Oncology. 30, 5 SUPPL. 16, p. 93-104 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

Specific keynote: genome copy number abnormalities in ovarian cancer.

Gray, J. W., Suzuki, S., Kuo, W. L., Polikoff, D., Deavers, M., Smith-McCune, K., Berchuck, A., Pinkel, D., Albertson, D. & Mills, G. B., Jan 2003, In : Gynecologic oncology. 88, 1 Pt 2, p. S16-21; discussion S22-24

Research output: Contribution to journalReview article

35 Scopus citations

Specific keynote: molecular therapeutics in ovarian cancer.

Mills, G. B., Fang, X., Lu, Y., Hasegawa, Y., Eder, A., Tanyi, J., Tabassam, F. H., Mao, M., Wang, H., Cheng, K. W., Nakayama, Y., Kuo, W., Erickson, J., Gershenson, D., Kohn, E. C., Jaffe, R., Bast, R. C. & Gray, J., Jan 2003, In : Gynecologic oncology. 88, 1 Pt 2, p. S88-92; discussion S93-96

Research output: Contribution to journalReview article

18 Scopus citations

The genetics and genomics of cancer

Balmain, A., Gray, J. & Ponder, B., Mar 2003, In : Nature genetics. 33, 3S, p. 238-244 7 p.

Research output: Contribution to journalReview article

435 Scopus citations

Translating laboratory knowledge into biological therapy and genetic analysis

Gray, J., Jan 1 2003, In : Breast Journal. 9, SUPPL. 1, p. S29-S31

Research output: Contribution to journalArticle

2002

Biallelic inactivation of the thyroid hormone receptor β1 gene in early stage breast cancer

Li, Z., Meng, Z. H., Chandrasekaran, R., Kuo, W. L., Collins, C. C., Gray, J. W. & Dairkee, S. H., Apr 1 2002, In : Cancer Research. 62, 7, p. 1939-1943 5 p.

Research output: Contribution to journalArticle

75 Scopus citations

Gene encoding protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

Anand, N., Murthy, S., Amann, G., Wernick, M., Porter, L. A., Cukier, I. H., Collins, C., Gray, J. W., Diebold, J., Demetrick, D. J. & Lee, J. M., Jul 2002, In : Nature genetics. 31, 3, p. 301-305 5 p.

Research output: Contribution to journalArticle

192 Scopus citations

Increased risk of local recurrence is associated with allelic loss in normal lobules of breast cancer patients

Li, Z., Moore, D. H., Meng, Z. H., Dairkee, S. H., Ljung, B. M. & Gray, J. W., Feb 15 2002, In : Cancer Research. 62, 4, p. 1000-1003 4 p.

Research output: Contribution to journalArticle

52 Scopus citations

Technical approaches for efficient, high precision nucleic acid analysis using DNA microarrays

Pinkel, D., Hamilton, G., Brown, N., Segraves, R., Huey, B., Snijders, A., Blackwood, S., Hindle, K., Law, S., Gray, J., Jain, A., Hanson, J., Nordmeyer, R. & Albertson, D., Jan 1 2002, In : Proceedings of SPIE-The International Society for Optical Engineering. 4626, p. 82-88 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2001

A 20q13.2 cancer amplicon: Novel sequence analysis tools

Volik, S., Gray, J., Kowbel, D. & Collins, C., 2001, In : Nature Genetics. 27, 4S, p. 94 1 p.

Research output: Contribution to journalArticle

Assembly of microarrays for genome-wide measurement of DNA copy number

Snijders, A. M., Nowak, N., Segraves, R., Blackwood, S., Brown, N., Conroy, J., Hamilton, G., Hindle, A. K., Huey, B., Kimura, K., Law, S., Myambo, K., Palmer, J., Ylstra, B., Yue, J. P., Gray, J. W., Jain, A. N., Pinkel, D. & Albertson, D. G., Dec 10 2001, In : Nature genetics. 29, 3, p. 263-264 2 p.

Research output: Contribution to journalArticle

738 Scopus citations

Comparative genomic hybridization.

DeVries, S., Gray, J. W., Pinkel, D., Waldman, F. M. & Sudar, D., May 2001, In : Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.]. Chapter 4, p. Unit4.6

Research output: Contribution to journalArticle

2 Scopus citations

Comprehensive genome sequence analysis of a breast cancer amplicon

Collins, C., Volik, S., Kowbel, D., Ginzinger, D., Ylstra, B., Cloutier, T., Hawkins, T., Predki, P., Martin, C., Wernick, M., Kuo, W. L., Alberts, A. & Gray, J. W., Sep 22 2001, In : Genome Research. 11, 6, p. 1034-1042 9 p.

Research output: Contribution to journalArticle

73 Scopus citations

Comprehensive sequence analysis of a human 20q13.2 cancer amplicon

Collins, C., Volik, S., Kowbel, D., Wernick, M., Hawkins, T., Predki, P., Kuo, W. L. & Gray, J., 2001, In : Nature Genetics. 27, 4S, p. 48 1 p.

Research output: Contribution to journalArticle

Erratum: Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas (Journal of Vascular Technology (2001) 29 (459-464))

Hodgson, G., Hager, J. H., Volik, S., Hariono, S., Wernick, M., Moore, D., Nowak, N., Albertson, D. G., Pinkel, D., Collins, C., Hanahan, D. & Gray, J. W., Dec 1 2001, In : Nature genetics. 29, 4, 1 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas

Hodgson, G., Hager, J. H., Volik, S., Hariono, S., Wernick, M., Moore, D., Albertson, D. G., Pinkel, D., Collins, C., Hanahan, D. & Gray, J. W., Jan 1 2001, In : Nature genetics. 29, 4, p. 459-464 6 p.

Research output: Contribution to journalArticle

249 Scopus citations

Genomics of islet cell carcinogenesis

Hager, J., Hodgson, G., Collins, C., Tsai, F. Y., Huszar, D., Gray, J. & Hanahan, D., Apr 2001, In : Nature genetics. 27, 4S, p. 57-58 2 p.

Research output: Contribution to journalArticle

Integration of cytogenetic landmarks into the draft sequence of the human genome

Cheung, V. G., Nowak, N., Jang, W., Kirsch, I. R., Zhao, S., Chen, X. N., Furey, T. S., Kim, U. J., Kuo, W. L., Olvier, M., Conroy, J., Kasprzyk, A., Massa, H., Yonescu, R., Sait, S., Thoreen, C., Snijders, A., Lemyre, E., Bailey, J. A., Bruzel, A. & 40 others, Burrill, W. D., Clegg, S. M., Collins, S., Dhami, P., Friedman, C., Han, C. S., Herrick, S., Lee, J., Ligon, A. H., Lowry, S., Moriey, M., Narasimhan, S., Osoegawa, K., Peng, Z., Plajzer-Frick, I., Quade, B. J., Scott, D., Sirotkin, K., Thorpe, A. A., Gray, J. W., Hudson, J., Pinkel, D., Ried, T., Rowen, L., Shen-Ong, G. L., Strausberg, R. L., Birney, E., Callen, D. F., Cheng, J. F., Cox, D. R., Doggett, N. A., Carter, N. P., Eichler, E. E., Haussler, D., Korenberg, J. R., Morton, C. C., Albertson, D., Schuler, G., De Jong, P. J. & Trask, B. J., Feb 15 2001, In : Nature. 409, 6822, p. 953-958 6 p.

Research output: Contribution to journalLetter

238 Scopus citations

Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival

Jain, A. N., Chin, K., Børresen-Dale, A. L., Erikstein, B. K., Lonning, P. E., Kaaresen, R. & Gray, J. W., Jul 24 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 14, p. 7952-7957 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

Response to neoadjuvant therapy for breast cancer by magnetic resonance imaging type, estrogen receptor status, grade, and comparative genomic hybridization

Esserman, L. J., Sudilovsky, D., Kuo, W. I., Gray, J. & Hylton, N., Dec 1 2001, In : Breast Cancer Research and Treatment. 69, 3, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Stromal-epithelial interactions in the progression of ovarian cancer: Influence and source of tumor stromal cells

Parrott, J. A., Nilsson, E., Mosher, R., Magrane, G., Albertson, D., Pinkel, D., Gray, J. W. & Skinner, M. K., Apr 25 2001, In : Molecular and Cellular Endocrinology. 175, 1-2, p. 29-39 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy

Mills, G. B., Lu, Y., Fang, X., Wang, H., Eder, A., Mao, M., Swaby, R., Cheng, K. W., Stokoe, D., Siminovitch, K., Jaffe, R. & Gray, J., Jan 1 2001, In : Seminars in Oncology. 28, 5 SUPPL. 16, p. 125-141 17 p.

Research output: Contribution to journalArticle

111 Scopus citations

The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells

Nonet, G. H., Stampfer, M. R., Chin, K., Gray, J. W., Collins, C. C. & Yaswen, P., Feb 15 2001, In : Cancer Research. 61, 4, p. 1250-1254 5 p.

Research output: Contribution to journalArticle

121 Scopus citations
2000

An approach to analysis of large-scale correlations between genome changes and clinical endpoints in ovarian cancer

Suzuki, S., Moore, D. H., Ginzinger, D. G., Godfrey, T. E., Barclay, J., Powell, B., Pinkel, D., Zaloudek, C., Lu, K., Mills, G., Berchuck, A. & Gray, J. W., Oct 1 2000, In : Cancer Research. 60, 19, p. 5382-5385 4 p.

Research output: Contribution to journalArticle

101 Scopus citations

ARHI is the center of allelic deletion on chromosome 1p31 in ovarian and breast cancers

Peng, H., Xu, F., Pershad, R., Hunt, K. K., Frazier, M. L., Berchuck, A., Gray, J. W., Hogg, D., Bast, R. C. & Yu, Y., May 19 2000, In : International Journal of Cancer. 86, 5, p. 690-694 5 p.

Research output: Contribution to journalArticle

52 Scopus citations

Genome changes and gene expression in human solid tumors

Gray, J. W. & Collins, C., Jan 1 2000, In : Carcinogenesis. 21, 3, p. 443-452 10 p.

Research output: Contribution to journalReview article

Open Access
165 Scopus citations

HYAL1(LUCA-1), a candidate tumor suppressor gene on chromosome 3p21.3, is inactivated in head and neck squamous cell carcinomas by aberrant splicing of pre-mRNA

Frost, G. I., Mohapatra, G., Wong, T. M., Csóka, A. B., Gray, J. W. & Stern, R., Feb 17 2000, In : Oncogene. 19, 7, p. 870-877 8 p.

Research output: Contribution to journalArticle

Open Access
70 Scopus citations

In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002)

Hu, L., Zaloudek, C., Mills, G. B., Gray, J. & Jaffe, R. B., Mar 1 2000, In : Clinical Cancer Research. 6, 3, p. 880-886 7 p.

Research output: Contribution to journalArticle

266 Scopus citations

Measurement of DNA copy number at microsatellite loci using quantitative PCR analysis

Ginzinger, D. G., Godfrey, T. E., Nigro, J., Moore, D. H., Suzuki, S., Pallavicini, M. G., Gray, J. W. & Jensen, R. H., Oct 1 2000, In : Cancer Research. 60, 19, p. 5405-5409 5 p.

Research output: Contribution to journalArticle

134 Scopus citations

Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene

Albertson, D. G., Ylstra, B., Segraves, R., Collins, C., Dairkee, S. H., Kowbel, D., Kuo, W. L., Gray, J. W. & Pinkel, D., Jun 1 2000, In : Nature genetics. 25, 2, p. 144-146 3 p.

Research output: Contribution to journalArticle

489 Scopus citations