• 65500 Citations
  • 111 h-Index
1971 …2020
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Research Output 1971 2020

Article
113 Citations (Scopus)

Detection of aneuploidy involving chromosomes 13, 18, or 21, by fluorescence in situ hybridization (FISH) to interphase and metaphase amniocytes

Kuo, W. L., Tenjin, H., Segraves, R., Pinkel, D., Golbus, M. S. & Gray, J., Jul 1991, In : American Journal of Human Genetics. 49, 1, p. 112-119 8 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 21
Interphase
Aneuploidy
329 Citations (Scopus)

Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization

Tkachuk, D. C., Westbrook, C. A., Andreeff, M., Donlon, T. A., Cleary, M. L., Suryanarayan, K., Homge, M., Redner, A., Gray, J. & Pinkel, D., Oct 26 1990, In : Science. 250, 4980, p. 559-562 4 p.

Research output: Contribution to journalArticle

abl Genes
In Situ Hybridization
Leukemia
Chromosomes, Human, Pair 22
Philadelphia Chromosome
45 Citations (Scopus)

Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization

Kallioniemi, A., Kallioniemi, O. P., Waidman, F. M., Chen, L. C., Yu, L. C., Fung, Y. K. T., Smith, H. S., Pinkel, D. & Gray, J., 1992, In : Cytogenetic and Genome Research. 60, 3-4, p. 190-193 4 p.

Research output: Contribution to journalArticle

Retinoblastoma Genes
Gene Dosage
Interphase
Metaphase
Fluorescence In Situ Hybridization
15 Citations (Scopus)

Dicentric chromosome frequency analysis using slit-scan flow cytometry

Lucas, J. N., Mullikin, J. C. & Gray, J., 1991, In : Cytometry. 12, 4, p. 316-322 7 p.

Research output: Contribution to journalArticle

Flow Cytometry
Chromosomes
Demecolcine
Propidium
Chromosomes, Human, Pair 1
524 Citations (Scopus)

Dicer, Drosha, and outcomes in patients with ovarian cancer

Merritt, W. M., Lin, Y. G., Han, L. Y., Kamat, A. A., Spannuth, W. A., Schmandt, R., Urbauer, D., Pennacchio, L. A., Cheng, J. F., Nick, A. M., Deavers, M. T., Mourad-Zeidan, A., Wang, H., Mueller, P., Lenburg, M. E., Gray, J., Mok, S., Birrer, M. J., Lopez-Berestein, G., Coleman, R. L. & 2 others, Bar-Eli, M. & Sood, A. K., Dec 18 2008, In : New England Journal of Medicine. 359, 25, p. 2641-2650 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Small Interfering RNA
DNA Mutational Analysis
Messenger RNA
RNA Interference
5 Citations (Scopus)

Differential staining of human and murine chromatin in situ by hybridization with species-specific satellite DNA probes

Weier, H. U. G., Zitzelsberger, H. F. & Gray, J., Feb 14 1992, In : Biochemical and Biophysical Research Communications. 182, 3, p. 1313-1319 7 p.

Research output: Contribution to journalArticle

Satellite DNA
DNA Probes
Chromatin
In Situ Hybridization
Chromosomes
17 Citations (Scopus)

Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

Risom, T., Langer, E. M., Chapman, M. P., Rantala, J., Fields, A. J., Boniface, C., Alvarez, M. J., Kendsersky, N. D., Pelz, C. R., Johnson-Camacho, K., Dobrolecki, L. E., Chin, K-Y., Aswani, A. J., Wang, N. J., Califano, A., Lewis, M. T., Tomlin, C. J., Spellman, P., Adey, A., Gray, J. & 1 others, Sears, R., Dec 1 2018, In : Nature Communications. 9, 1, 3815.

Research output: Contribution to journalArticle

plastic properties
breast
chromatin
Plasticity
drugs

DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters

Sutton, M. N., Lu, Z., Li, Y. C., Zhou, Y., Huang, T., Reger, A. S., Hurwitz, A. M., Palzkill, T., Logsdon, C., Liang, X., Gray, J. W., Nan, X., Hancock, J., Wahl, G. M. & Bast, R. C., Dec 10 2019, In : Cell Reports. 29, 11, p. 3448-3459.e6

Research output: Contribution to journalArticle

Open Access
Monomeric GTP-Binding Proteins
Phenotype
Mutation
Growth
Neoplasms
1 Citation (Scopus)

Disentangling multidimensional spatio-temporal data into their common and aberrant responses

Chang, Y. H., Korkola, J., Amin, D. N., Moasser, M. M., Carmena, J. M., Gray, J. & Tomlin, C. J., Apr 22 2015, In : PLoS One. 10, 4, e0121607.

Research output: Contribution to journalArticle

Experiments
Gene expression
Principal component analysis
Time series
methodology
37 Citations (Scopus)

Display and analysis of flow cytometric data.

Gray, J. & Dean, P. N., 1980, In : Annual Review of Biophysics and Bioengineering. 9, p. 509-539 31 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
Ultraviolet Rays
Caffeine
DNA
G2 Phase
Metaphase
22 Citations (Scopus)

DNA copy number changes associated with characteristic LOH in islet cell carcinomas of transgenic mice

Shi, Y. P., Naik, P., Dietrich, W. F., Gray, J., Hanahan, D. & Pinkel, D., 1997, In : Genes Chromosomes and Cancer. 19, 2, p. 104-111 8 p.

Research output: Contribution to journalArticle

Islet Cell Carcinoma
DNA Copy Number Variations
Comparative Genomic Hybridization
Loss of Heterozygosity
Transgenic Mice
10 Citations (Scopus)

Do breast cancer cell lines provide a relevant model of the patient tumor methylome?

Cope, L. M., Fackler, M. J., Lopez-Bujanda, Z., Wolff, A. C., Visvanathan, K., Gray, J., Sukumar, S. & Umbricht, C. B., Aug 26 2014, In : PLoS One. 9, 8, e105545.

Research output: Contribution to journalArticle

breast neoplasms
Tumors
Cells
cell lines
Breast Neoplasms
1 Citation (Scopus)

Dose-dependent response of KHT tumour cells to ARA-C

Dolbeare, F., Pallavicini, M. G. & Gray, J., 1982, In : Cell and Tissue Kinetics. 15, 6, p. 678 1 p.

Research output: Contribution to journalArticle

Neoplasms
72 Citations (Scopus)

Double labeling with iodo- and bromodeoxyuridine for cell kinetic studies

Shibui, S., Hoshino, T., Vanderlaan, M. & Gray, J., 1989, In : Journal of Histochemistry and Cytochemistry. 37, 7, p. 1007-1011 5 p.

Research output: Contribution to journalArticle

Idoxuridine
Bromodeoxyuridine
S Phase
Cell Line
Alkaline Phosphatase
40 Citations (Scopus)

Effect of methylglyoxal-bis (guanylhydrazone), an inhibitor of spermidine and spermine synthesis, on cell cycle traverse

Heby, O., Marton, L. J., Wilson, C. B. & Gray, J., 1977, In : European Journal of Cancer (1965). 13, 9, p. 1009-1017 9 p.

Research output: Contribution to journalArticle

Mitoguazone
Spermidine
Spermine
Cell Cycle
G1 Phase
76 Citations (Scopus)

Effects of methotrexate on transfected DNA stability in mammalian cells

Pallavicini, M. G., Deteresa, P. S., Rosette, C., Gray, J. & Wurm, F. M., Jan 1990, In : Molecular and Cellular Biology. 10, 1, p. 401-404 4 p.

Research output: Contribution to journalArticle

Methotrexate
Cultured Cells
Tetrahydrofolate Dehydrogenase
DNA
46 Citations (Scopus)

Efficient, interactive, and three-dimensional segmentation of cell nuclei in thick tissue sections

Lockett, S. J., Sudar, D., Thompson, C. T., Pinkel, D. & Gray, J., Apr 1 1998, In : Cytometry. 31, 4, p. 275-286 12 p.

Research output: Contribution to journalArticle

Cell Nucleus
Three-Dimensional Imaging
Research
11 Citations (Scopus)

EGFR intron 1 polymorphism in Asian populations and its correlation with EGFR gene expression and amplification in breast tumor tissues

Zhou, Q., Yin, B. C., Jada, S. R., Wan, T. L., Kuo, W. L., Gray, J., Lee, A. S. G. & Chowbay, B., Nov 2006, In : Cancer Biology and Therapy. 5, 11, p. 1445-1449 5 p.

Research output: Contribution to journalArticle

Dinucleotide Repeats
erbB-1 Genes
Gene Amplification
Introns
Breast Neoplasms
17 Citations (Scopus)

Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer

Mukhtar, R. A., Moore, A. P., Tandon, V. J., Nseyo, O., Twomey, P., Adisa, C. A., Eleweke, N., Au, A., Baehner, F. L., Moore, D. H., McGrath, M. S., Olopade, O. I., Gray, J., Campbell, M. J. & Esserman, L. J., Nov 2012, In : Annals of Surgical Oncology. 19, 12, p. 3979-3986 8 p.

Research output: Contribution to journalArticle

Proliferating Cell Nuclear Antigen
Macrophages
Breast Neoplasms
Neoplasms
Hormones
158 Citations (Scopus)

Emerging role of RAB GTPases in cancer and human disease

Cheng, K. W., Lahad, J. P., Gray, J. & Mills, G., Apr 1 2005, In : Cancer Research. 65, 7, p. 2516-2519 4 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Ovarian Neoplasms
Breast Neoplasms
Monomeric GTP-Binding Proteins
Neoplasms
10 Citations (Scopus)

Endocytic trafficking of laminin is controlled by dystroglycan and is disrupted in cancers

Leonoudakis, D., Huang, G., Akhavan, A., Fata, J. E., Singh, M., Gray, J. & Muschler, J., 2014, In : Journal of Cell Science. 127, 22, p. 4894-4903 10 p.

Research output: Contribution to journalArticle

Dystroglycans
Laminin
Neoplasms
Basement Membrane
Laminin Receptors
111 Citations (Scopus)

End-sequence profiling: Sequence-based analysis of aberrant genomes

Volik, S., Zhao, S., Chin, K-Y., Brebner, J. H., Herndon, D. R., Tao, Q., Kowbel, D., Huang, G., Lapuk, A., Kuo, W. L., Magrane, G., De Jong, P., Gray, J. & Collins, C., Jun 24 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 13, p. 7696-7701 6 p.

Research output: Contribution to journalArticle

Sequence Analysis
Genome
Bacterial Artificial Chromosomes
Haploidy
Fluorescence In Situ Hybridization
138 Citations (Scopus)

Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer

Zhou, Y., Yau, C., Gray, J., Chew, K., Dairkee, S. H., Moore, D. H., Eppenberger, U., Eppenberger-Castori, S. & Benz, C. C., 2007, In : BMC Cancer. 7, 59.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Transcription Factor AP-1
Tamoxifen
Estrogen Receptors
Breast Neoplasms
21 Citations (Scopus)

Enrichment of murine hemopoietic clonogenic cells by multivariate analyses and sorting

Pallavicini, M. G., Summers, L. J., Dean, P. N. & Gray, J., 1985, In : Experimental Hematology. 13, 11, p. 1173-1181 9 p.

Research output: Contribution to journalArticle

Multivariate Analysis
Granulocyte-Macrophage Progenitor Cells
Light
Stem Cells
Fluorescence
21 Citations (Scopus)

Enzymatic production of single-stranded DNA as a target for fluorescence in situ hybridization

van Dekken, H., Pinkel, D., Mullikin, J. & Gray, J., Sep 1988, In : Chromosoma. 97, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Single-Stranded DNA
Fluorescence In Situ Hybridization
Human Chromosomes
Digestion
Chromosomes
5 Citations (Scopus)

Epigenomic inactivation of RasGAPs activates RAS signaling in a subset of luminal B breast cancers

Sears, R. & Gray, J., Feb 1 2017, In : Cancer Discovery. 7, 2, p. 131-133 3 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Epigenomics
Breast Neoplasms
Neoplasm Metastasis
Proteins
435 Citations (Scopus)

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization

Kallioniemi, O. P., Kallioniemi, A., Kurisu, W., Thor, A., Chen, L. C., Smith, H. S., Waldman, F. M., Pinkel, D. & Gray, J., 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 12, p. 5321-5325 5 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Breast Neoplasms
Cell Line
Neoplasms
Chromosomes, Human, Pair 17
4 Citations (Scopus)

ERBB receptor regulation of ESX/ELF3 promotes invasion in breast epithelial cells

Coppe, J. P., Amend, C., Semeiks, J., Baehner, F. L., Bayani, N., Campisi, J., Benz, C. C., Gray, J. & Neve, R. M., 2010, In : Open Cancer Journal. 3, SPEC. ISSUE 1, p. 89-100 12 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Breast
Proto-Oncogene Proteins c-ets
Epithelial Cells
Breast Neoplasms
6 Citations (Scopus)

Erratum: Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas (Journal of Vascular Technology (2001) 29 (459-464))

Hodgson, G., Hager, J. H., Volik, S., Hariono, S., Wernick, M., Moore, D., Nowak, N., Albertson, D. G., Pinkel, D., Collins, C., Hanahan, D. & Gray, J., 2001, In : Nature Genetics. 29, 4, p. 491 1 p.

Research output: Contribution to journalArticle

Blood Vessels
Genome
Technology
Carcinoma
23 Citations (Scopus)

Erratum

Lucas, J. N., Tenjin, T., Straume, T., Pinkel, D., Moore, D., Litt, M. & Gray, J., 1989, In : International Journal of Radiation Biology. 56, 2, p. 201 1 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Erratum to Modeling precision treatment of breast cancer [Genome Biology, 14, (2013), R110]

Daemen, A., Griffith, O. L., Heiser, L., Wang, N. J., Enache, O. M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J., Griffith, M., Hur, J. S., Huh, N., Chung, J., Cope, L., Fackler, M. J., Umbricht, C., Sukumar, S., Seth, P., Sukhatme, V. P., Jakkula, L. R. & 7 others, Lu, Y., Mills, G., Cho, R. J., Collisson, E. A., van't Veer, L. J., Spellman, P. & Gray, J., May 12 2015, In : Genome Biology. 16, 1, 95.

Research output: Contribution to journalArticle

breast neoplasms
cancer
genome
Genome
Breast Neoplasms
49 Citations (Scopus)

ESR1 gene amplification in breast cancer: A common phenomenon? [1]

Brown, L. A., Hoog, J., Chin, S. F., Tao, Y., Zayed, A. A., Chin, K-Y., Teschendorff, A. E., Quackenbush, J. F., Marioni, J. C., Leung, S., Perou, C. M., Neilsen, T. O., Ellis, M., Gray, J., Bernard, P. S., Huntsman, D. G. & Caldas, C., Jul 2008, In : Nature Genetics. 40, 7, p. 806-807 2 p.

Research output: Contribution to journalArticle

150 Citations (Scopus)

ESX: A structurally unique Ets overexpressed early during human breast tumorigenesis

Chang, C. H., Scott, G. K., Kuo, W. L., Xiong, X., Suzdaltseva, Y., Park, J. W., Sayre, P., Erny, K., Collins, C., Gray, J. & Benz, C. C., 1997, In : Oncogene. 14, 13, p. 1617-1622 6 p.

Research output: Contribution to journalArticle

Carcinogenesis
Breast
Breast Neoplasms
Oncogenes
Serine
78 Citations (Scopus)

Evidence emerges for early metastasis and parallel evolution of primary and metastatic tumors

Gray, J., Jul 1 2003, In : Cancer Cell. 4, 1, p. 4-6 3 p.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Neoplasms
Epigenomics
Bone Marrow
Therapeutics
15 Citations (Scopus)

Evidence of a dominant transcriptional pathway which regulates an undifferentiated and complete metastatic phenotype

Barsky, S. H., Sternlicht, M. D., Safarians, S., Nguyen, M., Chin, K-Y., Stewart, S. D., Hiti, A. L. & Gray, J., 1997, In : Oncogene. 15, 17, p. 2077-2091 15 p.

Research output: Contribution to journalArticle

Phenotype
Cell Fusion
Angiogenesis Inhibitors
Hybrid Cells
Protease Inhibitors
21 Citations (Scopus)

Exact reconstruction of gene regulatory networks using compressive sensing

Chang, Y. H., Gray, J. & Tomlin, C. J., 2014, In : BMC Bioinformatics. 15, p. 400 1 p.

Research output: Contribution to journalArticle

Compressive Sensing
Gene Regulatory Networks
Gene Regulatory Network
Genes
Connectivity
59 Citations (Scopus)

Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease

Butler, T. M., Johnson-Camacho, K., Peto, M., Wang, N. J., Macey, T. A., Korkola, J., Koppie, T., Corless, C., Gray, J. & Spellman, P., Aug 28 2015, In : PLoS One. 10, 8, e0136407.

Research output: Contribution to journalArticle

Exome
Tumors
mutation
Mutation
neoplasms
100 Citations (Scopus)

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

Shain, A. H., Garrido, M., Botton, T., Talevich, E., Yeh, I., Sanborn, J. Z., Chung, J., Wang, N. J., Kakavand, H., Mann, G. J., Thompson, J. F., Wiesner, T., Roy, R., Olshen, A. B., Gagnon, A., Gray, J., Huh, N., Hur, J. S., Busam, K. J., Scolyer, R. A. & 3 others, Cho, R. J., Murali, R. & Bastian, B. C., Sep 29 2015, In : Nature Genetics. 47, 10, p. 1194-1199 6 p.

Research output: Contribution to journalArticle

Exome
Melanoma
Mutation
Mutagens
Phosphatidylinositol 3-Kinases
85 Citations (Scopus)

Exon-level microarray analyses identify alternative splicing programs in breast cancer

Lapuk, A., Marr, H., Jakkula, L., Pedro, H., Bhattacharya, S., Purdom, E., Hu, Z., Simpson, K., Pachter, L., Durinck, S., Wang, N., Parvin, B., Fontenay, G., Speed, T., Garbe, J., Stampfer, M., Bayandorian, H., Dorton, S., Clark, T. A., Schweitzer, A. & 5 others, Wyrobek, A., Feiler, H., Spellman, P., Conboy, J. & Gray, J., Jul 2010, In : Molecular Cancer Research. 8, 7, p. 961-974 14 p.

Research output: Contribution to journalArticle

Alternative Splicing
Microarray Analysis
Exons
Breast Neoplasms
Protein Isoforms
418 Citations (Scopus)

Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle

Kurki, P., Vanderlaan, M., Dolbeare, F., Gray, J. & Tan, E. M., 1986, In : Experimental Cell Research. 166, 1, p. 209-219 11 p.

Research output: Contribution to journalArticle

Cyclins
Proliferating Cell Nuclear Antigen
Cell Cycle
Fluorescent Antibody Technique
S Phase
8 Citations (Scopus)
Induced Hyperthermia
Permeability
Cell Survival
Cells
Heating
19 Citations (Scopus)

Factors that determine the in vivo dose-response relationship for stable chromosome aberrations in A-bomb survivors.

Awa, A. A., Nakano, M., Ohtaki, K., Kodama, Y., Lucas, J. & Gray, J., Mar 1992, In : Journal of Radiation Research. 33 Suppl, p. 206-214 9 p.

Research output: Contribution to journalArticle

Bombs
chromosome aberrations
Chromosome Aberrations
dose response
Survivors
53 Citations (Scopus)

FISH probes for mouse chromosome identification

Shi, Y. P., Mohapatra, G., Miller, J., Hanahan, D., Lander, E., Gold, P., Pinkel, D. & Gray, J., Oct 1 1997, In : Genomics. 45, 1, p. 42-47 6 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Telomere
Clone Cells
Chromosomes
Centromere

Flow cytometric (FCM) analysis of intestinal crypt cells in vivo: Cell cycle phase duration estimation and response to Ara-C

Pallavicini, M. G. & Gray, J., 1982, In : Cell and Tissue Kinetics. 15, 1, p. 109 1 p.

Research output: Contribution to journalArticle

Cytarabine
Cell Cycle
67 Citations (Scopus)

Flow cytometric analysis of bromodeoxyuridine substituted cells stained with 33258 Hoechst

Latt, S. A., George, Y. S. & Gray, J., 1977, In : Journal of Histochemistry and Cytochemistry. 25, 7, p. 927-934 8 p.

Research output: Contribution to journalArticle

Bisbenzimidazole
Bromodeoxyuridine
Fluorescence
DNA
Growth
12 Citations (Scopus)

Flow cytometric characterization of a Chinese hamster x man hybrid cell line retaining the human Y chromosome

Cremer, C., Gray, J. & Ropers, H. H., May 1982, In : Human Genetics. 60, 3, p. 262-266 5 p.

Research output: Contribution to journalArticle

Chromomycin A3
Chromosomes, Human, Y
Hybrid Cells
Cricetulus
Karyotype
878 Citations (Scopus)

Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine.

Dolbeare, F., Gratzner, H., Pallavicini, M. G. & Gray, J., Sep 1983, In : Proceedings of the National Academy of Sciences of the United States of America. 80, 18, p. 5573-5577 5 p.

Research output: Contribution to journalArticle

Bromodeoxyuridine
DNA
Cricetulus
Bone Marrow Cells
Ovary
7 Citations (Scopus)

Flow cytometry of isolated nuclei prepared from gL rat brain tumor

Hoshino, T., Gray, J. & Nomura, K., 1979, In : Laboratory Investigation. 41, 1, p. 72-76 5 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Flow Cytometry
S Phase
DNA
Neoplasms
22 Citations (Scopus)

Flow cytometry of mammalian sperm progress in DNA and morphology measurement

Pinkel, D., Dean, P., Lake, S., Peters, D., Mendelsohn, M., Gray, J., Van Dilla, M. & Gledhill, B., 1979, In : Journal of Histochemistry and Cytochemistry. 27, 1, p. 353-358 6 p.

Research output: Contribution to journalArticle