• 65064 Citations
  • 110 h-Index
1971 …2020
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Research Output 1971 2020

2010
140 Citations (Scopus)

A technical assessment of the utility of reverse phase protein arrays for the study of the functional proteome in non-microdissected human breast cancers

Hennessy, B. T., Lu, Y., Gonzalez-Angulo, A. M., Carey, M. S., Myhre, S., Ju, Z., Davies, M. A., Liu, W., Coombes, K., Meric-Bernstam, F., Bedrosian, I., McGahren, M., Agarwal, R., Zhang, F., Overgaard, J., Alsner, J., Neve, R. M., Kuo, W. L., Gray, J., Borresen-Dale, A. L. & 1 others, Mills, G., Dec 2010, In : Clinical Proteomics. 6, 4, p. 129-151 23 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Proteome
Breast Neoplasms
Antibodies
Tumors
36 Citations (Scopus)

Breast cancer genomes - form and function

Korkola, J. & Gray, J., Feb 2010, In : Current Opinion in Genetics and Development. 20, 1, p. 4-14 11 p.

Research output: Contribution to journalArticle

Genome
Breast Neoplasms
Epigenomics
Neoplasm Metastasis
Technology
10 Citations (Scopus)

Cancer: Genomics of metastasis

Gray, J., Apr 15 2010, In : Nature. 464, 7291, p. 989-990 2 p.

Research output: Contribution to journalArticle

Neoplasm Transplantation
DNA Mutational Analysis
DNA Copy Number Variations
alpha Catenin
disease prevalence
4 Citations (Scopus)

ERBB receptor regulation of ESX/ELF3 promotes invasion in breast epithelial cells

Coppe, J. P., Amend, C., Semeiks, J., Baehner, F. L., Bayani, N., Campisi, J., Benz, C. C., Gray, J. & Neve, R. M., 2010, In : Open Cancer Journal. 3, SPEC. ISSUE 1, p. 89-100 12 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Breast
Proto-Oncogene Proteins c-ets
Epithelial Cells
Breast Neoplasms
84 Citations (Scopus)

Exon-level microarray analyses identify alternative splicing programs in breast cancer

Lapuk, A., Marr, H., Jakkula, L., Pedro, H., Bhattacharya, S., Purdom, E., Hu, Z., Simpson, K., Pachter, L., Durinck, S., Wang, N., Parvin, B., Fontenay, G., Speed, T., Garbe, J., Stampfer, M., Bayandorian, H., Dorton, S., Clark, T. A., Schweitzer, A. & 5 others, Wyrobek, A., Feiler, H., Spellman, P., Conboy, J. & Gray, J., Jul 2010, In : Molecular Cancer Research. 8, 7, p. 961-974 14 p.

Research output: Contribution to journalArticle

Alternative Splicing
Microarray Analysis
Exons
Breast Neoplasms
Protein Isoforms
185 Citations (Scopus)

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

Weigelt, B., Lo, A. T., Park, C. C., Gray, J. & Bissell, M. J., Jul 2010, In : Breast Cancer Research and Treatment. 122, 1, p. 35-43 9 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Cell Line
Extracellular Matrix
Antibodies, Monoclonal, Humanized
Laminin
28 Citations (Scopus)

High-throughput method for analyzing methylation of CpGs in targeted genomic regions

Nautiyal, S., Carlton, V. E. H., Lu, Y., Ireland, J. S., Flaucher, D., Moorhead, M., Gray, J., Spellman, P., Mindrinos, M., Berg, P. & Faham, M., Jul 13 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 28, p. 12587-12592 6 p.

Research output: Contribution to journalArticle

Methylation
Essential Genes
DNA Methylation
Genetic Promoter Regions
Base Pairing
3470 Citations (Scopus)

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Verhaak, R. G. W., Hoadley, K. A., Purdom, E., Wang, V., Qi, Y., Wilkerson, M. D., Miller, C. R., Ding, L., Golub, T., Mesirov, J. P., Alexe, G., Lawrence, M., O'Kelly, M., Tamayo, P., Weir, B. A., Gabriel, S., Winckler, W., Gupta, S., Jakkula, L., Feiler, H. & 13 others, Hodgson, J. G., James, C. D., Sarkaria, J. N., Brennan, C., Kahn, A., Spellman, P., Wilson, R. K., Speed, T. P., Gray, J., Meyerson, M., Getz, G., Perou, C. M. & Hayes, D. N., Jan 19 2010, In : Cancer Cell. 17, 1, p. 98-110 13 p.

Research output: Contribution to journalArticle

Glioblastoma
Gene Expression
Atlases
Genome
Mutation
25 Citations (Scopus)

Linking changes in epithelial morphogenesis to cancer mutations using computational modeling

Rejniak, K. A., Wang, S. E., Bryce, N. S., Chang, H., Parvin, B., Jourquin, J., Estrada, L., Gray, J., Arteaga, C. L., Weaver, A. M., Quaranta, V. & Anderson, A. R. A., Aug 2010, In : PLoS Computational Biology. 6, 8, e1000900.

Research output: Contribution to journalArticle

Morphogenesis
Computational Modeling
morphogenesis
tumor
Linking
57 Citations (Scopus)

Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture

Han, J., Chang, H., Giricz, O., Lee, G. Y., Baehner, F. L., Gray, J., Bissell, M. J., Kenny, P. A. & Parvin, B., Feb 2010, In : PLoS Computational Biology. 6, 2, e1000684.

Research output: Contribution to journalArticle

Morphogenesis
morphogenesis
Breast Cancer
Cell culture
Phenotype
7 Citations (Scopus)

p27Kip1 mediates addiction of ovarian cancer cells to MYCC (c-MYC) and their dependence on MYC paralogs

Prathapam, T., Aleshin, A., Guan, Y., Gray, J. & Martin, G. S., Oct 15 2010, In : Journal of Biological Chemistry. 285, 42, p. 32529-32538 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Cells
Cyclin A
Small Interfering RNA
Cell Aging
28 Citations (Scopus)

Prediction of epigenetically regulated genes in breast cancer cell lines

Loss, L. A., Sadanandam, A., Durinck, S., Nautiyal, S., Flaucher, D., Carlton, V. E. H., Moorhead, M., Lu, Y., Gray, J., Faham, M., Spellman, P. & Parvin, B., Jun 4 2010, In : BMC Bioinformatics. 11, 305.

Research output: Contribution to journalArticle

Methylation
Breast Cancer
Genes
Cells
Breast Neoplasms
149 Citations (Scopus)

Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

Creighton, C. J., Fu, X., Hennessy, B. T., Casa, A. J., Zhang, Y., Gonzalez-Angulo, A. M., Lluch, A., Gray, J., Brown, P. H., Hilsenbeck, S. G., Osborne, C. K., Mills, G., Lee, A. V. & Schiff, R., Jun 22 2010, In : Breast Cancer Research. 12, 3, R40.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Estrogen Receptors
Proteomics
Breast Neoplasms
Growth Factor Receptors
12 Citations (Scopus)

Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities

Langland, G. T., Yannone, S. M., Langland, R. A., Nakao, A., Guan, Y., Long, S. B. T., Vonguyen, L., Chen, D. J., Gray, J. & Chen, F., Apr 2010, In : Oncology Reports. 23, 4, p. 1021-1026 6 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Radiation Tolerance
Ovarian Neoplasms
Cell Line
Radiation
228 Citations (Scopus)

Restriction of receptor movement alters cellular response: Physical force sensing by EphA2

Salaita, K., Nair, P. M., Petit, R. S., Neve, R. M., Das, D., Gray, J. & Groves, J. T., Mar 12 2010, In : Science. 327, 5971, p. 1380-1385 6 p.

Research output: Contribution to journalArticle

Ephrin-A1
Ligands
EphA2 Receptor
Disintegrins
Architectural Accessibility
21 Citations (Scopus)

Sparse multitask regression for identifying common mechanism of response to therapeutic targets

Zhang, K., Gray, J. & Parvin, B., Jun 1 2010, In : Bioinformatics. 26, 12, btq181.

Research output: Contribution to journalArticle

Cell Cycle
Regression
Cells
Synthetic Data
Gene Expression
69 Citations (Scopus)

The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer

Hu, Z., Huang, G., Sadanandam, A., Gu, S., Lenburg, M. E., Pai, M., Bayani, N., Blakely, E. A., Gray, J. & Mao, J. H., Mar 8 2010, In : Breast Cancer Research. 12, 2, R18.

Research output: Contribution to journalArticle

Cruciform DNA
Radiotherapy
Breast Neoplasms
Proteins
Messenger RNA
2009
13 Citations (Scopus)

A primer on regression methods for decoding cis-regulatory logic

Das, D., Pellegrini, M. & Gray, J., Jan 2009, In : PLoS Computational Biology. 5, 1, e1000269.

Research output: Contribution to journalArticle

Gene expression regulation
Transcriptional Regulatory Elements
Transcription factors
Nonlinear Dynamics
Genetic Models
24 Citations (Scopus)

A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047

Kuo, W. L., Das, D., Ziyad, S., Bhattacharya, S., Gibb, W. J., Heiser, L., Sadanandam, A., Fontenay, G. V., Hu, Z., Wang, N. J., Bayani, N., Feiler, H., Neve, R. M., Wyrobek, A. J., Spellman, P., Marton, L. J. & Gray, J., Dec 14 2009, In : BMC Medicine. 7, 77.

Research output: Contribution to journalArticle

Polyamines
Systems Analysis
Breast Neoplasms
Cell Line
Breast
266 Citations (Scopus)

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

Mirzoeva, O. K., Das, D., Heiser, L., Bhattacharya, S., Siwak, D., Gendelman, R., Bayani, N., Wang, N. J., Neve, R. M., Guan, Y., Hu, Z., Knight, Z., Feiler, H., Gascard, P., Parvin, B., Spellman, P., Shokat, K. M., Wyrobek, A. J., Bissell, M. J., McCormick, F. & 4 others, Kuo, W. L., Mills, G., Gray, J. & Korn, W. M., Jan 15 2009, In : Cancer Research. 69, 2, p. 565-572 8 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Mitogen-Activated Protein Kinase Kinases
Extracellular Signal-Regulated MAP Kinases
Phosphotransferases
Breast Neoplasms
568 Citations (Scopus)

Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

Hennessy, B. T., Gonzalez-Angulo, A. M., Stemke-Hale, K., Gilcrease, M. Z., Krishnamurthy, S., Lee, J. S., Fridlyand, J., Sahin, A., Agarwal, R., Joy, C., Liu, W., Stivers, D., Baggerly, K., Carey, M., Lluch, A., Monteagudo, C., He, X., Weigman, V., Fan, C., Palazzo, J. & 7 others, Hortobagyi, G. N., Nolden, L. K., Wang, N. J., Valero, V., Gray, J., Perou, C. M. & Mills, G., May 15 2009, In : Cancer Research. 69, 10, p. 4116-4124 9 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Mesenchymal Stromal Cells
Breast Neoplasms
Neoplasms
Neoplastic Stem Cells
84 Citations (Scopus)

Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts

Hodgson, J. G., Yeh, R. F., Ray, A., Wang, N. J., Smirnov, I., Yu, M., Hariono, S., Silber, J., Feiler, H., Gray, J., Spellman, P., Vandenberg, S. R., Berger, M. S. & James, C. D., Oct 2009, In : Neuro-Oncology. 11, 5, p. 477-487 11 p.

Research output: Contribution to journalArticle

Gene Dosage
Glioblastoma
Heterografts
Messenger RNA
Neoplasms
72 Citations (Scopus)

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

Wang, Y., Carlton, V. E., Karlin-Neumann, G., Sapolsky, R., Zhang, L., Moorhead, M., Wang, Z. C., Richardson, A. L., Warren, R., Walther, A., Bondy, M., Sahin, A., Krahe, R., Tuna, M., Thompson, P. A., Spellman, P., Gray, J., Mills, G. & Faham, M., 2009, In : BMC Medical Genomics. 2, 8.

Research output: Contribution to journalArticle

Molecular Probes
Paraffin
Formaldehyde
Genotype
DNA
19 Citations (Scopus)

Immutable functional attributes of histologic grade revealed by context-independent gene expression in primary breast cancer cells

Dairkee, S. H., Sayeed, A., Luciani, G., Champion, S., Zhenhang, M., Jakkula, L. R., Feiler, H., Gray, J. & Moore, D. H., Oct 1 2009, In : Cancer Research. 69, 19, p. 7826-7834 9 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Gene Expression
Neoplasms
Genes
Phenotype
51 Citations (Scopus)

Integrated analysis of breast cancer cell lines reveals unique signaling pathways

Heiser, L., Wang, N. J., Talcott, C. L., Laderoute, K. R., Knapp, M., Guan, Y., Hu, Z., Ziyad, S., Weber, B. L., Laquerre, S., Jackson, J. R., Wooster, R. F., Kuo, W., Gray, J. & Spellman, P., Mar 25 2009, In : Genome Biology. 10, 3, R31.

Research output: Contribution to journalArticle

breast neoplasms
cancer
cell lines
Breast Neoplasms
Cell Line
94 Citations (Scopus)

Integrative analysis of cyclin protein levels identifies cyclin B1 as a classifier and predictor of outcomes in breast cancer

Agarwal, R., Gonzalez-Angulo, A. M., Myhre, S., Carey, M., Lee, J. S., Overgaard, J., Alsner, J., Stemke-Hale, K., Lluch, A., Neve, R. M., Kuo, W. L., Sorlie, T., Sahin, A., Valero, V., Keyomarsi, K., Gray, J., Borresen-Dale, A. L., Mills, G. & Hennessy, B. T., Jun 1 2009, In : Clinical Cancer Research. 15, 11, p. 3654-3662 9 p.

Research output: Contribution to journalArticle

Cyclin B1
Cyclins
Cyclin D1
Breast Neoplasms
Proteins
17 Citations (Scopus)

LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer

Ong, D. C. T., Ho, Y. M., Rudduck, C., Chin, K-Y., Kuo, W. L., Lie, D. K. H., Chua, C. L. M., Tan, P. H., Eu, K. W., Seow-Choen, F., Wong, C. Y., Hong, G. S., Gray, J. & Lee, A. S. G., Nov 2009, In : Oncogene. 28, 47, p. 4189-4200 12 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Chromosomes
Breast Neoplasms
Neoplasms
decitabine
1 Citation (Scopus)

Morphometric subtyping for a panel of breast cancer cell lines

Han, J., Chang, H., Fontenay, G., Wang, N. J., Gray, J. & Parvin, B., 2009, Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009. p. 791-794 4 p. 5193168

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Cells
Breast Neoplasms
Cell Line
Assays
Pipelines
137 Citations (Scopus)

Picomolar sensitivity MRI and photoacoustic imaging of cobalt nanoparticles

Bouchard, L. S., Anwar, M. S., Liu, G. L., Hann, B., Xie, Z. H., Gray, J., Wang, X., Pines, A. & Chen, F. F., Mar 17 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 11, p. 4085-4089 5 p.

Research output: Contribution to journalArticle

Cobalt
Nanoparticles
Tomography
Gold
16 Citations (Scopus)

Sparse combinatorial inference with an application in cancer biology

Mukherjee, S., Pelech, S., Neve, R. M., Kuo, W. L., Ziyad, S., Spellman, P., Gray, J. & Speed, T. P., Jan 2009, In : Bioinformatics. 25, 2, p. 265-271 7 p.

Research output: Contribution to journalArticle

Boolean functions
Boolean Functions
Biology
Cancer
Statistical Models
40 Citations (Scopus)

Yin Yang 1 modulates taxane response in epithelial ovarian cancer

Matsumura, N., Huang, Z., Baba, T., Lee, P. S., Barnett, J. C., Mori, S., Chang, J. T., Kuo, W. L., Gusberg, A. H., Whitaker, R. S., Gray, J., Fujii, S., Berchuck, A. & Murphy, S. K., Feb 1 2009, In : Molecular Cancer Research. 7, 2, p. 210-220 11 p.

Research output: Contribution to journalArticle

Yin-Yang
Ovarian Neoplasms
Microtubules
Taxoids
Cell Line
2008
105 Citations (Scopus)

A human breast cell model of preinvasive to invasive transition

Rizki, A., Weaver, V. M., Lee, S. Y., Rozenberg, G. I., Chin, K-Y., Myers, C. A., Bascom, J. L., Mott, J. D., Semeiks, J. R., Grate, L. R., Mian, I. S., Borowsky, A. D., Jensen, R. A., Idowu, M. O., Chen, F., Chen, D. J., Petersen, O. W., Gray, J. & Bissell, M. J., Mar 1 2008, In : Cancer Research. 68, 5, p. 1378-1387 10 p.

Research output: Contribution to journalArticle

Breast
Phenotype
Matrix Metalloproteinases
Basement Membrane
Breast Neoplasms
92 Citations (Scopus)

Amplification of 11q13 in ovarian carcinoma

Brown, L. A., Kalloger, S. E., Miller, M. A., Shih, L. M., McKinney, S. E., Santos, J. L., Swenerton, K., Spellman, P., Gray, J., Gilks, C. B. & Huntsman, D. G., Jun 2008, In : Genes Chromosomes and Cancer. 47, 6, p. 481-489 9 p.

Research output: Contribution to journalArticle

Oncogenes
Ovarian Neoplasms
Carcinoma
Genes
Histology
642 Citations (Scopus)

An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

Stemke-Hale, K., Gonzalez-Angulo, A. M., Lluch, A., Neve, R. M., Kuo, W. L., Davies, M., Carey, M., Hu, Z., Guan, Y., Sahin, A., Symmans, W. F., Pusztai, L., Nolden, L. K., Horlings, H., Berns, K., Hung, M. C., Van De Vijver, M. J., Valero, V., Gray, J., Bernards, R. & 2 others, Mills, G. & Hennessy, B. T., Aug 1 2008, In : Cancer Research. 68, 15, p. 6084-6091 8 p.

Research output: Contribution to journalArticle

Proteomics
Phosphatidylinositol 3-Kinase
Breast Neoplasms
Mutation
Hormones
31 Citations (Scopus)

A sequence-based survey of the complex structural organization of tumor genomes

Raphael, B. J., Volik, S., Yu, P., Wu, C., Huang, G., Linardopoulou, E. V., Trask, B. J., Waldman, F., Costello, J., Pienta, K. J., Mills, G., Bajsarowicz, K., Kobayashi, Y., Sridharan, S., Paris, P. L., Tao, Q., Aerni, S. J., Brown, R. P., Bashir, A., Gray, J. & 6 others, Cheng, J. F., de Jong, P., Nefedov, M., Ried, T., Padilla-Nash, H. M. & Collins, C. C., Mar 25 2008, In : Genome Biology. 9, 3, R59.

Research output: Contribution to journalArticle

tumor
genome
Genome
neoplasms
Neoplasms

Cancer Genomics

Spellman, P., Costello, J. F. & Gray, J., 2008, The Molecular Basis of Cancer. Elsevier Inc., p. 267-282 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genomics
Neoplasms
4503 Citations (Scopus)

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

McLendon, R., Friedman, A., Bigner, D., Van Meir, E. G., Brat, D. J., Mastrogianakis, G. M., Olson, J. J., Mikkelsen, T., Lehman, N., Aldape, K., Yung, W. K. A., Bogler, O., Weinstein, J. N., VandenBerg, S., Berger, M., Prados, M., Muzny, D., Morgan, M., Scherer, S., Sabo, A. & 211 others, Nazareth, L., Lewis, L., Hall, O., Zhu, Y., Ren, Y., Alvi, O., Yao, J., Hawes, A., Jhangiani, S., Fowler, G., San Lucas, A., Kovar, C., Cree, A., Dinh, H., Santibanez, J., Joshi, V., Gonzalez-Garay, M. L., Miller, C. A., Milosavljevic, A., Donehower, L., Wheeler, D. A., Gibbs, R. A., Cibulskis, K., Sougnez, C., Fennell, T., Mahan, S., Wilkinson, J., Ziaugra, L., Onofrio, R., Bloom, T., Nicol, R., Ardlie, K., Baldwin, J., Gabriel, S., Lander, E. S., Ding, L., Fulton, R. S., McLellan, M. D., Wallis, J., Larson, D. E., Shi, X., Abbott, R., Fulton, L., Chen, K., Koboldt, D. C., Wendl, M. C., Meyer, R., Tang, Y., Lin, L., Osborne, J. R., Dunford-Shore, B. H., Miner, T. L., Delehaunty, K., Markovic, C., Swift, G., Courtney, W., Pohl, C., Abbott, S., Hawkins, A., Leong, S., Haipek, C., Schmidt, H., Wiechert, M., Vickery, T., Scott, S., Dooling, D. J., Chinwalla, A., Weinstock, G. M., Mardis, E. R., Wilson, R. K., Getz, G., Winckler, W., Verhaak, R. G. W., Lawrence, M. S., O'Kelly, M., Robinson, J., Alexe, G., Beroukhim, R., Carter, S., Chiang, D., Gould, J., Gupta, S., Korn, J., Mermel, C., Mesirov, J., Monti, S., Nguyen, H., Parkin, M., Reich, M., Stransky, N., Weir, B. A., Garraway, L., Golub, T., Meyerson, M., Chin, L., Protopopov, A., Zhang, J., Perna, I., Aronson, S., Sathiamoorthy, N., Ren, G., Yao, J., Wiedemeyer, W. R., Kim, H., Sek, W. K., Xiao, Y., Kohane, I. S., Seidman, J., Park, P. J., Kucherlapati, R., Laird, P. W., Cope, L., Herman, J. G., Weisenberger, D. J., Pan, F., Van Den Berg, D., Van Neste, L., Joo, M. Y., Schuebel, K. E., Baylin, S. B., Absher, D. M., Li, J. Z., Southwick, A., Brady, S., Aggarwal, A., Chung, T., Sherlock, G., Brooks, J. D., Myers, R. M., Spellman, P., Purdom, E., Jakkula, L. R., Lapuk, A. V., Marr, H., Dorton, S., Yoon, G. C., Han, J., Ray, A., Wang, V., Durinck, S., Robinson, M., Wang, N. J., Vranizan, K., Peng, V., Van Name, E., Fontenay, G. V., Ngai, J., Conboy, J. G., Parvin, B., Feiler, H., Speed, T. P., Gray, J., Brennan, C., Socci, N. D., Olshen, A., Taylor, B. S., Lash, A., Schultz, N., Reva, B., Antipin, Y., Stukalov, A., Gross, B., Cerami, E., Wei, Q. W., Qin, L. X., Seshan, V. E., Villafania, L., Cavatore, M., Borsu, L., Viale, A., Gerald, W., Sander, C., Ladanyi, M., Perou, C. M., Hayes, D. N., Topal, M. D., Hoadley, K. A., Qi, Y., Balu, S., Shi, Y., Wu, J., Penny, R., Bittner, M., Shelton, T., Lenkiewicz, E., Morris, S., Beasley, D., Sanders, S., Kahn, A., Sfeir, R., Chen, J., Nassau, D., Feng, L., Hickey, E., Barker, A., Gerhard, D. S., Vockley, J., Compton, C., Vaught, J., Fielding, P., Ferguson, M. L., Schaefer, C., Zhang, J., Madhavan, S., Buetow, K. H., Collins, F., Good, P., Guyer, M., Ozenberger, B., Peterson, J. & Thomson, E., Oct 23 2008, In : Nature. 455, 7216, p. 1061-1068 8 p.

Research output: Contribution to journalArticle

Glioblastoma
Atlases
Genes
DNA Methylation
Neoplasms
523 Citations (Scopus)

Dicer, Drosha, and outcomes in patients with ovarian cancer

Merritt, W. M., Lin, Y. G., Han, L. Y., Kamat, A. A., Spannuth, W. A., Schmandt, R., Urbauer, D., Pennacchio, L. A., Cheng, J. F., Nick, A. M., Deavers, M. T., Mourad-Zeidan, A., Wang, H., Mueller, P., Lenburg, M. E., Gray, J., Mok, S., Birrer, M. J., Lopez-Berestein, G., Coleman, R. L. & 2 others, Bar-Eli, M. & Sood, A. K., Dec 18 2008, In : New England Journal of Medicine. 359, 25, p. 2641-2650 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Small Interfering RNA
DNA Mutational Analysis
Messenger RNA
RNA Interference
49 Citations (Scopus)

ESR1 gene amplification in breast cancer: A common phenomenon? [1]

Brown, L. A., Hoog, J., Chin, S. F., Tao, Y., Zayed, A. A., Chin, K-Y., Teschendorff, A. E., Quackenbush, J. F., Marioni, J. C., Leung, S., Perou, C. M., Neilsen, T. O., Ellis, M., Gray, J., Bernard, P. S., Huntsman, D. G. & Caldas, C., Jul 2008, In : Nature Genetics. 40, 7, p. 806-807 2 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Ovarian cancer: Linking genomics to new target discovery and molecular markers - The way ahead

Hennessy, B. T., Murph, M., Nanjundan, M., Carey, M., Auersperg, N., Almeida, J., Coombes, K. R., Liu, J., Lu, Y., Gray, J. & Mills, G., 2008, Advances in Experimental Medicine and Biology. Vol. 617. p. 23-40 18 p. (Advances in Experimental Medicine and Biology; vol. 617).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Human Genome
Tumor Biomarkers
Genomics
Ovarian Neoplasms
221 Citations (Scopus)

Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities

Press, J. Z., De Luca, A., Boyd, N., Young, S., Troussard, A., Ridge, Y., Kaurah, P., Kalloger, S. E., Blood, K. A., Smith, M., Spellman, P., Wang, Y., Miller, D. M., Horsman, D., Faham, M., Gilks, C. B., Gray, J. & Huntsman, D. G., Jan 22 2008, In : BMC Cancer. 8, 17.

Research output: Contribution to journalArticle

Epigenomics
Carcinoma
Mutation
Loss of Heterozygosity
Ovarian Neoplasms
22 Citations (Scopus)

Overexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: A role in ovarian pathogenesis

Nanjundan, M., Cheng, K. W., Zhang, F., Lahad, J., Kuo, W. L., Schmandt, R., Smith-McCune, K., Fishman, D., Gray, J. & Mills, G., Aug 2008, In : Molecular Oncology. 2, 2, p. 164-181 18 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
RNA
Carcinogenesis
Growth
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
1 Citation (Scopus)

Preface

Mendelsohn, J., Howley, P. M., Israel, M. A., Gray, J. & Thompson, C. B., 2008, In : Unknown Journal.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature

Tutt, A., Wang, A., Rowland, C., Gillett, C., Lau, K., Chew, K., Dai, H., Kwok, S., Ryder, K., Shu, H., Springall, R., Cane, P., McCallie, B., Kam-Morgan, L., Anderson, S., Buerger, H., Gray, J., Bennington, J., Esserman, L., Hastie, T. & 4 others, Broder, S., Sninsky, J., Brandt, B. & Waldman, F., Nov 21 2008, In : BMC Cancer. 8, 339.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Neoplasm Metastasis
Polymerase Chain Reaction
Survival
16 Citations (Scopus)

The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas

Sun, Y., Wong, N., Guan, Y., Salamanca, C. M., Jung, C. C., Lee, J. M., Gray, J. & Auersperg, N., Oct 15 2008, In : International Journal of Cancer. 123, 8, p. 1761-1769 9 p.

Research output: Contribution to journalArticle

Peptide Elongation Factors
Apoptosis
Carcinoma
Oncogenes
Small Interfering RNA
28 Citations (Scopus)

The Molecular Basis of Cancer

Mendelsohn, J., Howley, P. M., Israel, M. A., Gray, J. & Thompson, C. B., 2008, Elsevier Inc.

Research output: Book/ReportBook

Color
Gene therapy
Biotechnology
Websites
Neoplasms
213 Citations (Scopus)

Translating insights from the cancer genome into clinical practice

Chin, L. & Gray, J., Apr 3 2008, In : Nature. 452, 7187, p. 553-563 11 p.

Research output: Contribution to journalArticle

Genome
Neoplasms
Epigenomics
Atlases
Noise
25 Citations (Scopus)

Translational Research Working Group developmental pathway for biospecimen-based assessment modalities

Srivastava, S., Gray, J., Reid, B. J., Grad, O., Greenwood, A. & Hawk, E. T., Sep 15 2008, In : Clinical Cancer Research. 14, 18, p. 5672-5677 6 p.

Research output: Contribution to journalArticle

Translational Medical Research
Biomarkers
National Cancer Institute (U.S.)
Neoplasms
2007
44 Citations (Scopus)

Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers.

Yau, C., Fedele, V., Roydasgupta, R., Fridlyand, J., Hubbard, A., Gray, J., Chew, K., Dairkee, S. H., Moore, D. H., Schittulli, F., Tommasi, S., Paradiso, A., Albertson, D. G. & Benz, C. C., 2007, In : Breast cancer research : BCR. 9, 5

Research output: Contribution to journalArticle

Transcriptome
Genome
Hormones
Breast Neoplasms
Estrogen Receptors
87 Citations (Scopus)

Amplification of MDS1/EVI1 and EVI1, located in the 3q26.2 amplicon, is associated with favorable patient prognosis in ovarian cancer

Nanjundan, M., Nakayama, Y., Kwai, W. C., Lahad, J., Liu, J., Lu, K., Kuo, W. L., Smith-McCune, K., Fishman, D., Gray, J. & Mills, G., Apr 1 2007, In : Cancer Research. 67, 7, p. 3074-3084 11 p.

Research output: Contribution to journalArticle

Virus Integration
Myelodysplastic Syndromes
Ovarian Neoplasms
DNA
Bacterial Artificial Chromosomes