• 67302 Citations
  • 113 h-Index
1971 …2020

Research output per year

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Research Output

2014

Reply to Colorectal cancer classification based on gene expression is not associated with FOLFIRI response

Sadanandam, A., Gray, J. & Hanahan, D., Nov 1 2014, In : Nature medicine. 20, 11, p. 1231-1232 2 p.

Research output: Contribution to journalLetter

4 Scopus citations

The Molecular Basis of Cancer: Fourth Edition

Mendelsohn, J., Gray, J. W., Howley, P. M., Israel, M. A. & Thompson, C. B., Mar 1 2014, Elsevier Inc. 863 p.

Research output: Book/ReportBook

Transcription Restores DNA Repair to Heterochromatin, Determining Regional Mutation Rates in Cancer Genomes

Zheng, C. L., Wang, N. J., Chung, J., Moslehi, H., Sanborn, J. Z., Hur, J. S., Collisson, E. A., Vemula, S. S., Naujokas, A., Chiotti, K. E., Cheng, J. B., Fassihi, H., Blumberg, A. J., Bailey, C. V., Fudem, G. M., Mihm, F. G., Cunningham, B. B., Neuhaus, I. M., Liao, W., Oh, D. H. & 10 others, Cleaver, J. E., LeBoit, P. E., Costello, J. F., Lehmann, A. R., Gray, J. W., Spellman, P. T., Arron, S. T., Huh, N., Purdom, E. & Cho, R. J., Nov 20 2014, In : Cell Reports. 9, 4, p. 1228-1234 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Understanding and Using Information about Cancer Genomes

Spellman, P. T., Stuart, J. & Gray, J. W., Mar 1 2014, The Molecular Basis of Cancer: Fourth Edition. Elsevier Inc., p. 357-368.e3

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

A colorectal cancer classification system that associates cellular phenotype and responses to therapy

Sadanandam, A., Lyssiotis, C. A., Homicsko, K., Collisson, E. A., Gibb, W. J., Wullschleger, S., Ostos, L. C. G., Lannon, W. A., Grotzinger, C., Del Rio, M., Lhermitte, B., Olshen, A. B., Wiedenmann, B., Cantley, L. C., Gray, J. W. & Hanahan, D., May 2013, In : Nature medicine. 19, 5, p. 619-625 7 p.

Research output: Contribution to journalArticle

507 Scopus citations

Adaptive H-extrema for automatic immunogold particle detection

Thibault, G., Iljin, K., Arthur, C., Shafran, I. & Gray, J., Dec 1 2013, Progress in Pattern Recognition, Image Analysis, Computer Vision, and Applications - 18th Iberoamerican Congress, CIARP 2013, Proceedings. PART 2 ed. p. 238-245 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 8259 LNCS, no. PART 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

A robust prognostic signature for hormone-positive node-negative breast cancer

Griffith, O. L., Pepin, F., Enache, O. M., Heiser, L. M., Collisson, E. A., Spellman, P. T. & Gray, J. W., Oct 11 2013, In : Genome Medicine. 5, 10, 92.

Research output: Contribution to journalArticle

11 Scopus citations

CpG island shore methylation regulates caveolin-1 expression in breast cancer

Rao, X., Evans, J., Chae, H., Pilrose, J., Kim, S., Yan, P., Huang, R. L., Lai, H. C., Lin, H., Liu, Y., Miller, D., Rhee, J. K., Huang, Y. W., Gu, F., Gray, J. W., Huang, T. M. & Nephew, K. P., Sep 19 2013, In : Oncogene. 32, 38, p. 4519-4528 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

C-Src modulates estrogen-induced stress and apoptosis in estrogen-deprived breast cancer cells

Fan, P., Griffith, O. L., Agboke, F. A., Anur, P., Zou, X., McDaniel, R. E., Creswell, K., Kim, S. H., Katzenellenbogen, J. A., Gray, J. W. & Jordan, V. C., Jul 15 2013, In : Cancer Research. 73, 14, p. 4510-4520 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target

Timmerman, L. A., Holton, T., Yuneva, M., Louie, R. J., Padró, M., Daemen, A., Hu, M., Chan, D. A., Ethier, S. P., van'tVeer, L. J., Polyak, K., McCormick, F. & Gray, J. W., Oct 14 2013, In : Cancer Cell. 24, 4, p. 450-465 16 p.

Research output: Contribution to journalArticle

225 Scopus citations

Identification and quantification of AKT isoforms and phosphoforms in breast cancer using a novel nanofluidic immunoassay

Iacovides, D. C., Johnson, A. B., Wang, N., Boddapati, S., Korkola, J. & Gray, J. W., Nov 1 2013, In : Molecular and Cellular Proteomics. 12, 11, p. 3210-3220 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer

Rhee, J. K., Kim, K., Chae, H., Evans, J., Yan, P., Zhang, B. T., Gray, J., Spellman, P., Huang, T. H. M., Nephew, K. P. & Kim, S., Oct 2013, In : Nucleic acids research. 41, 18, p. 8464-8474 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association

Chang, H., Han, J., Borowsky, A., Loss, L., Gray, J. W., Spellman, P. T. & Parvin, B., Apr 15 2013, In : IEEE Transactions on Medical Imaging. 32, 4, p. 670-682 13 p., 6374258.

Research output: Contribution to journalArticle

65 Scopus citations

Metrics other than potency reveal systematic variation in responses to cancer drugs

Fallahi-Sichani, M., Honarnejad, S., Heiser, L. M., Gray, J. W. & Sorger, P. K., Nov 1 2013, In : Nature Chemical Biology. 9, 11, p. 708-714 7 p.

Research output: Contribution to journalArticle

155 Scopus citations

Modeling precision treatment of breast cancer

Daemen, A., Griffith, O. L., Heiser, L. M., Wang, N. J., Enache, O. M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J. E., Griffith, M., Hur, J. S., Huh, N., Chung, J., Cope, L., Fackler, M. J., Umbricht, C., Sukumar, S., Seth, P., Sukhatme, V. P., Jakkula, L. R. & 7 others, Lu, Y., Mills, G. B., Cho, R. J., Collisson, E. A., van't Veer, L. J., Spellman, P. T. & Gray, J. W., Dec 10 2013, In : Genome biology. 14, 10, R110.

Research output: Contribution to journalArticle

Open Access
140 Scopus citations

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

Verhaak, R. G. W., Tamayo, P., Yang, J. Y., Hubbard, D., Zhang, H., Creighton, C. J., Fereday, S., Lawrence, M., Carter, S. L., Mermel, C. H., Kostic, A. D., Etemadmoghadam, D., Saksena, G., Cibulskis, K., Duraisamy, S., Levanon, K., Sougnez, C., Tsherniak, A., Gomez, S., Onofrio, R. & 21 others, Gabriel, S., Chin, L., Zhang, N., Spellman, P. T., Zhang, Y., Akbani, R., Hoadley, K. A., Kahn, A., Köbel, M., Huntsman, D., Soslow, R. A., Defazio, A., Birrer, M. J., Gray, J. W., Weinstein, J. N., Bowtell, D. D., Drapkin, R., Mesirov, J. P., Getz, G., Levine, D. A. & Meyerson, M., Jan 2 2013, In : Journal of Clinical Investigation. 123, 1, p. 517-525 9 p.

Research output: Contribution to journalArticle

293 Scopus citations

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Lovci, M. T., Ghanem, D., Marr, H., Arnold, J., Gee, S., Parra, M., Liang, T. Y., Stark, T. J., Gehman, L. T., Hoon, S., Massirer, K. B., Pratt, G. A., Black, D. L., Gray, J. W., Conboy, J. G. & Yeo, G. W., Dec 1 2013, In : Nature Structural and Molecular Biology. 20, 12, p. 1434-1442 9 p.

Research output: Contribution to journalArticle

130 Scopus citations

Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling

Nan, X., Collisson, E. A., Lewis, S., Huang, J., Tamgüney, T. M., Liphardt, J. T., McCormick, F., Gray, J. W. & Chu, S., Nov 12 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 46, p. 18519-18524 6 p.

Research output: Contribution to journalArticle

91 Scopus citations

Targeting uPAR with antagonistic recombinant human antibodies in aggressive breast cancer

Le Beau, A. M., Duriseti, S., Murphy, S. T., Pepin, F., Hann, B., Gray, J. W., Van Brocklin, H. F. & Craik, C. S., Apr 1 2013, In : Cancer Research. 73, 7, p. 2070-2081 12 p.

Research output: Contribution to journalArticle

44 Scopus citations
2012

A Central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma

Collisson, E. A., Trejo, C. L., Silva, J. M., Gu, S., Korkola, J. E., Heiser, L. M., Charles, R. P., Rabinovich, B. A., Hann, B., Dankort, D., Spellman, P. T., Phillips, W. A., Gray, J. W. & McMahon, M., Aug 2012, In : Cancer discovery. 2, 8, p. 685-693 9 p.

Research output: Contribution to journalArticle

146 Scopus citations

ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells

Ordinario, E., Han, H. J., Furuta, S., Heiser, L. M., Jakkula, L. R., Rodier, F., Spellman, P. T., Campisi, J., Gray, J. W., Bissell, M. J., Kohwi, Y. & Kohwi-Shigematsu, T., Dec 10 2012, In : PloS one. 7, 12, e51786.

Research output: Contribution to journalArticle

17 Scopus citations

Bayesian Inference of Signaling Network Topology in a Cancer Cell Line

Hill, S. M., Lu, Y., Molina, J., Heiser, L. M., Spellman, P. T., Speed, T. P., Gray, J. W., Mills, G. B. & Mukherjee, S., Nov 2012, In : Bioinformatics. 28, 21, p. 2804-2810 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Chemotherapy response and recurrence-free survival in Neoadjuvant breast cancer depends on biomarker profiles: Results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)

Esserman, L. J., Berry, D. A., Cheang, M. C. U., Yau, C., Perou, C. M., Carey, L., De Michele, A., Gray, J. W., Conway-Dorsey, K., Lenburg, M. E., Buxton, M. B., Davis, S. E., Van't Veer, L. J., Hudis, C., Chin, K., Wolf, D., Krontiras, H., Montgomery, L., Tripathy, D., Lehman, C. & 14 others, Liu, M. C., Olopade, O. I., Rugo, H. S., Carpenter, J. T., Livasy, C., Dressler, L., Chhieng, D., Singh, B., Mies, C., Rabban, J., Chen, Y. Y., Giri, D., Au, A. & Hylton, N., Apr 1 2012, In : Breast Cancer Research and Treatment. 132, 3, p. 1049-1062 14 p.

Research output: Contribution to journalArticle

205 Scopus citations

Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib

Daemen, A., Wolf, D. M., Korkola, J. E., Griffith, O. L., Frankum, J. R., Brough, R., Jakkula, L. R., Wang, N. J., Natrajan, R., Reis-Filho, J. S., Lord, C. J., Ashworth, A., Spellman, P. T., Gray, J. W. & Van'T Veer, L. J., Sep 2012, In : Breast Cancer Research and Treatment. 135, 2, p. 505-517 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer

Mukhtar, R. A., Moore, A. P., Tandon, V. J., Nseyo, O., Twomey, P., Adisa, C. A., Eleweke, N., Au, A., Baehner, F. L., Moore, D. H., McGrath, M. S., Olopade, O. I., Gray, J. W., Campbell, M. J. & Esserman, L. J., Nov 1 2012, In : Annals of surgical oncology. 19, 12, p. 3979-3986 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Genetic Differences in Transcript Responses to Low-Dose Ionizing Radiation Identify Tissue Functions Associated with Breast Cancer Susceptibility

Snijders, A. M., Marchetti, F., Bhatnagar, S., Duru, N., Han, J., Hu, Z., Mao, J. H., Gray, J. W. & Wyrobek, A. J., Oct 15 2012, In : PloS one. 7, 10, e45394.

Research output: Contribution to journalArticle

16 Scopus citations

Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome

Engler, D. A., Gupta, S., Growdon, W. B., Drapkin, R. I., Nitta, M., Sergent, P. A., Allred, S. F., Gross, J., Deavers, M. T., Kuo, W. L., Karlan, B. Y., Rueda, B. R., Orsulic, S., Gershenson, D. M., Birrer, M. J., Gray, J. W. & Mohapatra, G., Feb 15 2012, In : PloS one. 7, 2, e30996.

Research output: Contribution to journalArticle

25 Scopus citations

Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: Field cancerization or contaminating tumor cells?

Sadanandam, A., Lal, A., Benz, S. C., Eppenberger-Castori, S., Scott, G., Gray, J. W., Spellman, P., Waldman, F. & Benz, C. C., Dec 1 2012, In : Breast Cancer Research and Treatment. 136, 3, p. 693-703 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Genomics: The breast cancer landscape

Gray, J. & Druker, B., Jun 21 2012, In : Nature. 486, 7403, p. 328-329 2 p.

Research output: Contribution to journalShort survey

33 Scopus citations

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target

McElwee, J. L., Mohanan, S., Griffith, O. L., Breuer, H. C., Anguish, L. J., Cherrington, B. D., Palmer, A. M., Howe, L. R., Subramanian, V., Causey, C. P., Thompson, P. R., Gray, J. W. & Coonrod, S. A., Oct 30 2012, In : BMC cancer. 12, 500.

Research output: Contribution to journalArticle

63 Scopus citations

Integrating biological knowledge into variable selection: an empirical Bayes approach with an application in cancer biology

Hill, S. M., Neve, R. M., Bayani, N., Kuo, W. L., Ziyad, S., Spellman, P. T., Gray, J. W. & Mukherjee, S., May 11 2012, In : BMC bioinformatics. 13, 1, 94.

Research output: Contribution to journalArticle

16 Scopus citations

Learning invariant features of tumor signatures

Le, Q. V., Han, J., Gray, J. W., Spellman, P. T., Borowsky, A. & Parvin, B., Aug 15 2012, 2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012 - Proceedings. p. 302-305 4 p. 6235544. (Proceedings - International Symposium on Biomedical Imaging).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

23 Scopus citations

Lectin chromatography/mass spectrometry discovery workflow identifies putative biomarkers of aggressive breast cancers

Drake, P. M., Schilling, B., Niles, R. K., Prakobphol, A., Li, B., Jung, K., Cho, W., Braten, M., Inerowicz, H. D., Williams, K., Albertolle, M., Held, J. M., Iacovides, D., Sorensen, D. J., Griffith, O. L., Johansen, E., Zawadzka, A. M., Cusack, M. P., Allen, S., Gormley, M. & 6 others, Hall, S. C., Witkowska, H. E., Gray, J. W., Regnier, F., Gibson, B. W. & Fisher, S. J., Apr 6 2012, In : Journal of Proteome Research. 11, 4, p. 2508-2520 13 p.

Research output: Contribution to journalArticle

42 Scopus citations

Loss of cell-surface laminin anchoring promotes tumor growth and is associated with poor clinical outcomes

Akhavan, A., Griffith, O. L., Soroceanu, L., Leonoudakis, D., Luciani-Torres, M. G., Daemen, A., Gray, J. W. & Muschler, J. L., May 15 2012, In : Cancer Research. 72, 10, p. 2578-2588 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Omics and therapy - A basis for precision medicine

Garay, J. P. & Gray, J. W., Apr 2012, In : Molecular Oncology. 6, 2, p. 128-139 12 p.

Research output: Contribution to journalReview article

30 Scopus citations

Optimization-based inference for temporally evolving networks with applications in biology

Chang, Y. H., Gray, J. & Tomlin, C., Dec 1 2012, In : Journal of Computational Biology. 19, 12, p. 1307-1323 17 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: Results from the I-SPY 1 TRIAL - CALGB 150007/150012, ACRIN 6657

Esserman, L. J., Berry, D. A., DeMichele, A., Carey, L., Davis, S. E., Buxton, M., Hudis, C., Gray, J. W., Perou, C., Yau, C., Livasy, C., Krontiras, H., Montgomery, L., Tripathy, D., Lehman, C., Liu, M. C., Olopade, O. I., Rugo, H. S., Carpenter, J. T., Dressler, L. & 8 others, Chhieng, D., Singh, B., Mies, C., Rabban, J., Chen, Y. Y., Giri, D., Van't Veer, L. & Hylton, N., Sep 10 2012, In : Journal of Clinical Oncology. 30, 26, p. 3242-3249 8 p.

Research output: Contribution to journalArticle

258 Scopus citations

Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress

Cheng, K. W., Agarwal, R., Mitra, S., Lee, J. S., Carey, M., Gray, J. W. & Mills, G. B., Feb 1 2012, In : EMBO Molecular Medicine. 4, 2, p. 125-141 17 p.

Research output: Contribution to journalArticle

47 Scopus citations

Subtype and pathway specific responses to anticancer compounds in breast cancer

Heiser, L. M., Sadanandam, A., Kuo, W. L., Benz, S. C., Goldstein, T. C., Ng, S., Gibb, W. J., Wang, N. J., Ziyad, S., Tong, F., Bayani, N., Hu, Z., Billig, J. I., Dueregger, A., Lewis, S., Jakkula, L., Korkola, J. E., Durinck, S., Pepin, F., Guan, Y. & 23 others, Purdom, E., Neuvial, P., Bengtsson, H., Wood, K. W., Smith, P. G., Vassilev, L. T., Hennessy, B. T., Greshock, J., Bachman, K. E., Hardwicke, M. A., Park, J. W., Marton, L. J., Wolf, D. M., Collisson, E. A., Neve, R. M., Mills, G. B., Speed, T. P., Feiler, H. S., Richard, F. W., Haussler, D., Stuart, J. M., Gray, J. W. & Spellman, P. T., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 2724-2729 6 p.

Research output: Contribution to journalArticle

274 Scopus citations

The transcription factor ZNF217 Is a prognostic biomarker and therapeutic target during breast cancer progression

Littlepage, L. E., Adler, A. S., Kouros-Mehr, H., Huang, G., Chou, J., Krig, S. R., Griffi th, O. L., Korkola, J. E., Qu, K., Lawson, D. A., Xue, Q., Sternlicht, M. D., Dijkgraaf, G. J. P., Yaswen, P., Rugo, H. S., Sweeney, C. A., Collins, C. C., Gray, J. W., Chang, H. Y. & Werb, Z., Jul 2012, In : Cancer discovery. 2, 7, p. 638-651 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

What are we learning from the cancer genome?

Collisson, E. A., Cho, R. J. & Gray, J. W., Nov 1 2012, In : Nature Reviews Clinical Oncology. 9, 11, p. 621-630 10 p.

Research output: Contribution to journalReview article

33 Scopus citations

Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors

Petrillo, L. A., Wolf, D. M., Kapoun, A. M., Wang, N. J., Barczak, A., Xiao, Y., Korkaya, H., Baehner, F., Lewicki, J., Wicha, M., Park, J. W., Spellman, P. T., Gray, J. W., Van'T Veer, L. & Esserman, L. J., Oct 1 2012, In : Breast Cancer Research and Treatment. 135, 3, p. 913-922 10 p.

Research output: Contribution to journalArticle

28 Scopus citations
2011

A new treasure in the breast cancer gene hunt

Spellman, P. & Gray, J., Apr 1 2011, In : Nature medicine. 17, 4, p. 422-423 2 p.

Research output: Contribution to journalArticle

13 Scopus citations

Comparison of sparse coding and kernel methods for histopathological classification of gliobastoma multiforme

Han, J., Chang, H., Loss, L., Zhang, K., Baehner, F. L., Gray, J. W., Spellman, P. & Parvin, B., Nov 2 2011, 2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11. p. 711-714 4 p. 5872505. (Proceedings - International Symposium on Biomedical Imaging).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

22 Scopus citations

Erratum: Topographic enhancement mapping of the cancer-associated breast stroma using breast MRI (Integrative Biology (2011) 3 (910-921) DOI:10.1039/C1IB00043H)

Nabavizadeh, N., Klifa, C., Newitt, D., Lu, Y., Chen, Y. Y., Hsu, H., Fisher, C., Tokuyasu, T., Olshen, A. B., Spellman, P., Gray, J. W., Hylton, N. & Park, C. C., Dec 2011, In : Integrative Biology. 3, 12, 1 p.

Research output: Contribution to journalComment/debate

Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence

Fackler, M. J., Umbricht, C. B., Williams, D., Argani, P., Cruz, L. A., Merino, V. F., Teo, W. W., Zhang, Z., Huang, P., Visvananthan, K., Marks, J., Ethier, S., Gray, J. W., Wolff, A. C., Cope, L. M. & Sukumar, S., Oct 1 2011, In : Cancer Research. 71, 19, p. 6195-6207 13 p.

Research output: Contribution to journalArticle

137 Scopus citations

Integrated genomic analyses of ovarian carcinoma

Bell, D., Berchuck, A., Birrer, M., Chien, J., Cramer, D. W., Dao, F., Dhir, R., Disaia, P., Gabra, H., Glenn, P., Godwin, A. K., Gross, J., Hartmann, L., Huang, M., Huntsman, D. G., Iacocca, M., Imielinski, M., Kalloger, S., Karlan, B. Y., Levine, D. A. & 240 others, Mills, G. B., Morrison, C., Mutch, D., Olvera, N., Orsulic, S., Park, K., Petrelli, N., Rabeno, B., Rader, J. S., Sikic, B. I., Smith-Mccune, K., Sood, A. K., Bowtell, D., Penny, R., Testa, J. R., Chang, K., Dinh, H. H., Drummond, J. A., Fowler, G., Gunaratne, P., Hawes, A. C., Kovar, C. L., Lewis, L. R., Morgan, M. B., Newsham, I. F., Santibanez, J., Reid, J. G., Trevino, L. R., Wu, Y. Q., Wang, M., Muzny, D. M., Wheeler, D. A., Gibbs, R. A., Getz, G., Lawrence, M. S., Cibulskis, K., Sivachenko, A. Y., Sougnez, C., Voet, D., Wilkinson, J., Bloom, T., Ardlie, K., Fennell, T., Baldwin, J., Gabriel, S., Lander, E. S., Ding, L., Fulton, R. S., Koboldt, D. C., McLellan, M. D., Wylie, T., Walker, J., O'Laughlin, M., Dooling, D. J., Fulton, L., Abbott, R., Dees, N. D., Zhang, Q., Kandoth, C., Wendl, M., Schierding, W., Shen, D., Harris, C. C., Schmidt, H., Kalicki, J., Delehaunty, K. D., Fronick, C. C., Demeter, R., Cook, L., Wallis, J. W., Lin, L., Magrini, V. J., Hodges, J. S., Eldred, J. M., Smith, S. M., Pohl, C. S., Vandin, F., Raphael, B. J., Weinstock, G. M., Mardis, E. R., Wilson, R. K., Meyerson, M., Winckler, W., Verhaak, R. G. W., Carter, S. L., Mermel, C. H., Saksena, G., Nguyen, H., Onofrio, R. C., Hubbard, D., Gupta, S., Crenshaw, A., Ramos, A. H., Chin, L., Protopopov, A., Zhang, J., Kim, T. M., Perna, I., Xiao, Y., Zhang, H., Ren, G., Sathiamoorthy, N., Park, R. W., Lee, E., Park, P. J., Kucherlapati, R., Absher, D. M., Waite, L., Sherlock, G., Brooks, J. D., Li, J. Z., Xu, J., Myers, R. M., Laird, P. W., Cope, L., Herman, J. G., Shen, H., Weisenberger, D. J., Noushmehr, H., Pan, F., Triche, T., Berman, B. P., Van Den Berg, D. J., Buckley, J., Baylin, S. B., Spellman, P. T., Purdom, E., Neuvial, P., Bengtsson, H., Jakkula, L. R., Durinck, S., Han, J., Dorton, S., Marr, H., Choi, Y. G., Wang, V., Wang, N. J., Ngai, J., Conboy, J. G., Parvin, B., Feiler, H. S., Speed, T. P., Gray, J. W., Socci, N. D., Liang, Y., Taylor, B. S., Schultz, N., Borsu, L., Lash, A. E., Brennan, C., Viale, A., Sander, C., Ladanyi, M., Hoadley, K. A., Meng, S., Du, Y., Shi, Y., Li, L., Turman, Y. J., Zang, D., Helms, E. B., Balu, S., Zhou, X., Wu, J., Topal, M. D., Hayes, D. N., Perou, C. M., Wu, C. J., Shukla, S., Sivachenko, A., Jing, R., Liu, Y., Noble, M., Carter, H., Kim, D., Karchin, R., Korkola, J. E., Heiser, L. M., Cho, R. J., Hu, Z., Cerami, E., Olshen, A., Reva, B., Antipin, Y., Shen, R., Mankoo, P., Sheridan, R., Ciriello, G., Chang, W. K., Bernanke, J. A., Haussler, D., Benz, C. C., Stuart, J. M., Benz, S. C., Sanborn, J. Z., Vaske, C. J., Zhu, J., Szeto, C., Scott, G. K., Yau, C., Wilkerson, M. D., Zhang, N., Akbani, R., Baggerly, K. A., Yung, W. K., Weinstein, J. N., Shelton, T., Grimm, D., Hatfield, M., Morris, S., Yena, P., Rhodes, P., Sherman, M., Paulauskis, J., Millis, S., Kahn, A., Greene, J. M., Sfeir, R., Jensen, M. A., Chen, J., Whitmore, J., Alonso, S., Jordan, J., Chu, A., Barker, A., Compton, C., Eley, G., Ferguson, M., Fielding, P., Gerhard, D. S., Myles, R., Schaefer, C., Mills Shaw, K. R., Vaught, J., Vockley, J. B., Good, P. J., Guyer, M. S., Ozenberger, B., Peterson, J. & Thomson, E., Jun 30 2011, In : Nature. 474, 7353, p. 609-615 7 p.

Research output: Contribution to journalArticle

3923 Scopus citations

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

Wang, N. J., Sanborn, Z., Arnett, K. L., Bayston, L. J., Liao, W., Proby, C. M., Leigh, I. M., Collisson, E. A., Gordon, P. B., Jakkula, L., Pennypacker, S., Zou, Y., Sharma, M., North, J. P., Vemula, S. S., Mauro, T. M., Neuhaus, I. M., LeBoit, P. E., Hur, J. S., Park, K. & 13 others, Huh, N., Kwok, P. Y., Arron, S. T., Massion, P. P., Bale, A. E., Haussler, D., Cleaver, J. E., Gray, J. W., Spellman, P. T., South, A. P., Aster, J. C., Blacklow, S. C. & Cho, R. J., Oct 25 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 43, p. 17761-17766 6 p.

Research output: Contribution to journalArticle

260 Scopus citations

Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer

Krig, S. R., Frietze, S., Simion, C., Miller, J. K., Fry, W. H. D., Rafidi, H., Kotelawala, L., Qi, L., Griffith, O. L., Gray, J. W., Carraway, K. L. & Sweeney, C., Oct 1 2011, In : Molecular Cancer Research. 9, 10, p. 1406-1417 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Morphometic analysis of TCGA glioblastoma multiforme

Chang, H., Fontenay, G. V., Han, J., Cong, G., Baehner, F. L., Gray, J. W., Spellman, P. T. & Parvin, B., Dec 20 2011, In : BMC bioinformatics. 12, 484.

Research output: Contribution to journalArticle

33 Scopus citations