• 67731 Citations
  • 113 h-Index
1971 …2020

Research output per year

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Research Output

Article

ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin

Fleyshman, D., Cheney, P., Ströse, A., Mudambi, S., Safina, A., Commane, M., Purmal, A., Morgan, K., Wang, N. J., Gray, J., Spellman, P., Issaeva, N. & Gurova, K., Feb 1 2016, In : Cell Cycle. 15, 3, p. 455-470 16 p.

Research output: Contribution to journalArticle

1 Scopus citations
125 Scopus citations

A sequence-based survey of the complex structural organization of tumor genomes

Raphael, B. J., Volik, S., Yu, P., Wu, C., Huang, G., Linardopoulou, E. V., Trask, B. J., Waldman, F., Costello, J., Pienta, K. J., Mills, G. B., Bajsarowicz, K., Kobayashi, Y., Sridharan, S., Paris, P. L., Tao, Q., Aerni, S. J., Brown, R. P., Bashir, A., Gray, J. W. & 6 others, Cheng, J. F., de Jong, P., Nefedov, M., Ried, T., Padilla-Nash, H. M. & Collins, C. C., Mar 25 2008, In : Genome biology. 9, 3, R59.

Research output: Contribution to journalArticle

31 Scopus citations

Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells

Lorenzi, P. L., Reinhold, W. C., Rudelius, M., Gunsior, M., Shankavaram, U., Bussey, K. J., Scherf, U., Eichler, G. S., Martin, S. E., Chin, K., Gray, J. W., Kohn, E. C., Horak, I. D., Von Hoff, D. D., Raffeld, M., Goldsmith, P. K., Caplen, N. J. & Weisntein, J. N., Nov 2006, In : Molecular cancer therapeutics. 5, 11, p. 2613-2623 11 p.

Research output: Contribution to journalArticle

69 Scopus citations

Assembly of microarrays for genome-wide measurement of DNA copy number

Snijders, A. M., Nowak, N., Segraves, R., Blackwood, S., Brown, N., Conroy, J., Hamilton, G., Hindle, A. K., Huey, B., Kimura, K., Law, S., Myambo, K., Palmer, J., Ylstra, B., Yue, J. P., Gray, J. W., Jain, A. N., Pinkel, D. & Albertson, D. G., Dec 10 2001, In : Nature genetics. 29, 3, p. 263-264 2 p.

Research output: Contribution to journalArticle

742 Scopus citations

Assessing human germ-cell mutagenesis in the postgenome era: A celebration of the legacy of William Lawson (Bill) Russell

Wyrobek, A. J., Mulvihill, J. J., Wassom, J. S., Malling, H. V., Shelby, M. D., Lewis, S. E., Witt, K. L., Preston, R. J., Perreault, S. D., Allen, J. W., DeMarini, D. M., Woychik, R. P., Bishop, J. B., Anderson, D., Arnheim, N., Boice, J. D., Bridges, B. A., Crow, J. F., Dubrova, Y. E., Eichenlaub-Ritter, U. & 16 others, Erickson, R. P., Fridlyand, J., Gray, J., Hanawalt, P. C., Handel, M. A., Marchetti, F., Mohrenweiser, H. W., Moyzis, R. K., Primig, M., Russell, L. B., Sankaranarayanan, K., Skinner, M. K., Shoubridge, E. A., Taylor, J. A., Trasler, J. M. & Vasicek, T. J., Feb 2007, In : Environmental and Molecular Mutagenesis. 48, 2, p. 71-95 25 p.

Research output: Contribution to journalArticle

47 Scopus citations

A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047

Kuo, W. L., Das, D., Ziyad, S., Bhattacharya, S., Gibb, W. J., Heiser, L. M., Sadanandam, A., Fontenay, G. V., Hu, Z., Wang, N. J., Bayani, N., Feiler, H. S., Neve, R. M., Wyrobek, A. J., Spellman, P. T., Marton, L. J. & Gray, J. W., Dec 14 2009, In : BMC Medicine. 7, 77.

Research output: Contribution to journalArticle

25 Scopus citations

A technical assessment of the utility of reverse phase protein arrays for the study of the functional proteome in non-microdissected human breast cancers

Hennessy, B. T., Lu, Y., Gonzalez-Angulo, A. M., Carey, M. S., Myhre, S., Ju, Z., Davies, M. A., Liu, W., Coombes, K., Meric-Bernstam, F., Bedrosian, I., McGahren, M., Agarwal, R., Zhang, F., Overgaard, J., Alsner, J., Neve, R. M., Kuo, W. L., Gray, J. W., Borresen-Dale, A. L. & 1 others, Mills, G. B., Dec 1 2010, In : Clinical Proteomics. 6, 4, p. 129-151 23 p.

Research output: Contribution to journalArticle

145 Scopus citations

ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells

Ordinario, E., Han, H. J., Furuta, S., Heiser, L. M., Jakkula, L. R., Rodier, F., Spellman, P. T., Campisi, J., Gray, J. W., Bissell, M. J., Kohwi, Y. & Kohwi-Shigematsu, T., Dec 10 2012, In : PloS one. 7, 12, e51786.

Research output: Contribution to journalArticle

17 Scopus citations

A t-statistic for objective interpretation of comparative genomic hybridization (CGH) profiles

Moore, D. H., Pallavicini, M., Cher, M. L. & Gray, J. W., Jul 1 1997, In : Cytometry. 28, 3, p. 183-190 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Atypical PKCι contributes to poor prognosis through loss of apical-basal polarity and Cyclin E overexpression in ovarian cancer

Eder, A. M., Sui, X., Rosen, D. G., Nolden, L. K., Cheng, K. W., Lahad, J. P., Kango-Singh, M., Lu, K. H., Warneke, C. L., Atkinson, E. M., Bedrosian, I., Keyomarsi, K., Kuo, W. L., Gray, J. W., Yin, J. C. P., Liu, J., Halder, G. & Mills, G. B., Aug 30 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 35, p. 12519-12524 6 p.

Research output: Contribution to journalArticle

195 Scopus citations

Automated detection of chromosome aberration using color information

Chen, C. H., Wang, Y., Mitra, S. K. & Gray, J., Mar 1 1990, In : Proceedings of SPIE - The International Society for Optical Engineering. 1192, p. 339-343 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

Mirzoeva, O. K., Das, D., Heiser, L. M., Bhattacharya, S., Siwak, D., Gendelman, R., Bayani, N., Wang, N. J., Neve, R. M., Guan, Y., Hu, Z., Knight, Z., Feiler, H. S., Gascard, P., Parvin, B., Spellman, P. T., Shokat, K. M., Wyrobek, A. J., Bissell, M. J., McCormick, F. & 4 others, Kuo, W. L., Mills, G. B., Gray, J. W. & Korn, W. M., Jan 15 2009, In : Cancer Research. 69, 2, p. 565-572 8 p.

Research output: Contribution to journalArticle

274 Scopus citations

Bayesian Inference of Signaling Network Topology in a Cancer Cell Line

Hill, S. M., Lu, Y., Molina, J., Heiser, L. M., Spellman, P. T., Speed, T. P., Gray, J. W., Mills, G. B. & Mukherjee, S., Nov 2012, In : Bioinformatics. 28, 21, p. 2804-2810 7 p.

Research output: Contribution to journalArticle

65 Scopus citations

Bayesian network inference modeling identifies TRIB1 as a novel regulator of cell-cycle progression and survival in cancer cells

Gendelman, R., Xing, H., Mirzoeva, O. K., Sarde, P., Curtis, C., Feiler, H., McDonagh, P., Gray, J., Khalil, I. & Korn, W. M., 2017, In : Cancer Research. 77, 7, p. 1575-1585 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Biallelic inactivation of the thyroid hormone receptor β1 gene in early stage breast cancer

Li, Z., Meng, Z. H., Chandrasekaran, R., Kuo, W. L., Collins, C. C., Gray, J. W. & Dairkee, S. H., Apr 1 2002, In : Cancer Research. 62, 7, p. 1939-1943 5 p.

Research output: Contribution to journalArticle

75 Scopus citations

Bivariate flout cytometric analysis of murine intestinal epithelial cells for cytokinetic studies

Pallavicini, M. G., Ng, C. R. & Gray, J. W., Jan 1984, In : Cytometry. 5, 1, p. 55-62 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Breast tumor copy number aberration phenotypes and genomic instability

Fridlyand, J., Snijders, A. M., Ylstra, B., Li, H., Olshen, A., Segraves, R., Dairkee, S., Tokuyasu, T., Ljung, B. M., Jain, A. N., McLennan, J., Ziegler, J., Chin, K., Devries, S., Feiler, H., Gray, J. W., Waldman, F., Pinkel, D. & Albertson, D. G., Apr 18 2006, In : BMC cancer. 6, 96.

Research output: Contribution to journalArticle

228 Scopus citations

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

Rai, R., Dai, H., Multani, A. S., Li, K., Chin, K., Gray, J., Lahad, J. P., Liang, J., Mills, G. B., Meric-Bernstam, F. & Lin, S. Y., Aug 2006, In : Cancer Cell. 10, 2, p. 145-157 13 p.

Research output: Contribution to journalArticle

120 Scopus citations

Cationic polymer modified mesoporous silica nanoparticles for targeted siRNA delivery to HER2+ breast cancer

Ngamcherdtrakul, W., Morry, J., Gu, S., Castro, D. J., Goodyear, S. M., Sangvanich, T., Reda, M. M., Lee, R., Mihelic, S. A., Beckman, B. L., Hu, Z., Gray, J. W. & Yantasee, W., May 13 2015, In : Advanced Functional Materials. 25, 18, p. 2646-2659 14 p.

Research output: Contribution to journalArticle

101 Scopus citations

Causal network inference using biochemical kinetics

Oates, C. J., Dondelinger, F., Bayani, N., Korkola, J., Gray, J. W. & Mukherjee, S., Sep 1 2014, In : Bioinformatics. 30, 17, p. i468-i474

Research output: Contribution to journalArticle

32 Scopus citations

CCR5 Governs DNA damage repair and breast cancer stem cell expansion

Jiao, X., Velasco-Velazquez, M. A., Wang, M., Li, Z., Rui, H., Peck, A. R., Korkola, J. E., Chen, X., Xu, S., DuHadaway, J. B., Guerrero-Rodriguez, S., Addya, S., Sicoli, D., Mu, Z., Zhang, G., Stucky, A., Zhang, X., Cristofanilli, M., Fatatis, A., Gray, J. W. & 3 others, Zhong, J. F., Prendergast, G. C. & Pestell, R. G., Apr 1 2018, In : Cancer Research. 78, 7, p. 1657-1671 15 p.

Research output: Contribution to journalArticle

29 Scopus citations

Cell cycle analysis from computer synthesis of deoxyribonucleic acid histograms

Gray, J. W., Jan 1 1974, In : Journal of Histochemistry and Cytochemistry. 22, 7, p. 642-650 9 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

CELL‐CYCLE ANALYSIS OF PERTURBED CELL POPULATIONS: COMPUTER SIMULATION OF SEQUENTIAL DNA DISTRIBUTIONS

Gray, J., 1976, In : Cell Proliferation. 9, 6, p. 499-516 18 p.

Research output: Contribution to journalArticle

78 Scopus citations

Cell‐Cycle Analysis Using A Monoclonal Antibody to Brdurd

Dean, P. N., Dolbeare, F., Gratzner, H., Rice, G. C. & Gray, J., 1984, In : Cell Proliferation. 17, 4, p. 427-436 10 p.

Research output: Contribution to journalArticle

183 Scopus citations

Cell cycle analysis using flow cytometry

Gray, J. W., Dolbeare, F., Pallavicini, M. G., Beisker, W. & Waldman, F., Jan 1 1986, In : International Journal of Radiation Biology. 49, 2, p. 237-255 19 p.

Research output: Contribution to journalArticle

48 Scopus citations

Cell cycle analysis using numerical simulation of bivariate DNA/bromodeoxyuridine distributions

Yanagisawa, M., Dolbeare, F., Todoroki, T. & Gray, J. W., Nov 1985, In : Cytometry. 6, 6, p. 550-562 13 p.

Research output: Contribution to journalArticle

37 Scopus citations

Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival

Gast, C. E., Silk, A. D., Zarour, L., Riegler, L., Burkhart, J. G., Gustafson, K. T., Parappilly, M. S., Roh-Johnson, M., Goodman, J. R., Olson, B., Schmidt, M., Swain, J. R., Davies, P. S., Shasthri, V., Iizuka, S., Flynn, P., Watson, S., Korkola, J., Courtneidge, S. A., Fischer, J. M. & 8 others, Jaboin, J., Billingsley, K. G., Lopez, C. D., Burchard, J., Gray, J., Coussens, L. M., Sheppard, B. C. & Wong, M. H., Sep 12 2018, In : Science Advances. 4, 9, eaat7828.

Research output: Contribution to journalArticle

43 Scopus citations

Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine

Asai, A., Shibui, S., Barker, M., Vanderlaan, M., Gray, J. W. & Hoshino, T., Jan 1 1990, In : Journal of neurosurgery. 73, 2, p. 254-258 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Cellular effect of high doses of silica-coated quantum dot profiled with high throughput gene expression analysis and high content cellomics measurements

Zhang, T., Stilwell, J. L., Gerion, D., Ding, L., Elboudwarej, O., Cooke, P. A., Gray, J. W., Alivisatos, A. P. & Chen, F. F., Apr 2006, In : Nano Letters. 6, 4, p. 800-808 9 p.

Research output: Contribution to journalArticle

302 Scopus citations

Centromeric index measurement by slit‐scan flow cytometry

Lucas, J. N., Gray, J. W., Peters, D. C. & Van Dilla, M. A., Sep 1983, In : Cytometry. 4, 2, p. 109-116 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Centromeric index versus DNA content flow karyotypes of human chromosomes measured by means of slit‐scan flow cytometry

Lucas, J. N. & Gray, J. W., May 1987, In : Cytometry. 8, 3, p. 273-279 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Changes in L-ornithine decarboxylase activity during the cell cycle

Heby, O., Gray, J. W., Lindl, P. A., Marton, L. J. & Wilson, C. B., Jul 12 1976, In : Biochemical and Biophysical Research Communications. 71, 1, p. 99-105 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Chapter 21 Using Monoclonal Antibodies in Bromodeoxyuridine—DNA Analysis

Dolbeare, F., Kuo, W. L., Beisker, W., Vanderlaan, M. & Gray, J. W., Jan 1 1990, In : Methods in cell biology. 33, C, p. 207-216 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Characterization and organization of DNA sequences adjacent to the human telomere associated repeat (TTAGGG)n

Weber, B., Collins, C., Robbins, C., Magenis, R. E., Delaney, A. D., Gray, J. W. & Hayden, M. R., Jun 11 1990, In : Nucleic acids research. 18, 11, p. 3353-3361 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

Hennessy, B. T., Gonzalez-Angulo, A. M., Stemke-Hale, K., Gilcrease, M. Z., Krishnamurthy, S., Lee, J. S., Fridlyand, J., Sahin, A., Agarwal, R., Joy, C., Liu, W., Stivers, D., Baggerly, K., Carey, M., Lluch, A., Monteagudo, C., He, X., Weigman, V., Fan, C., Palazzo, J. & 7 others, Hortobagyi, G. N., Nolden, L. K., Wang, N. J., Valero, V., Gray, J. W., Perou, C. M. & Mills, G. B., May 15 2009, In : Cancer Research. 69, 10, p. 4116-4124 9 p.

Research output: Contribution to journalArticle

587 Scopus citations

Characterization of somatic cell hybrids by bivariate flow karyotyping and fluorescence in situ hybridization

Trask, B. J., van den Engh, G., Christensen, M., Massa, H. F., Gray, J. W. & Van Dilla, M., Mar 1 1991, In : Somatic Cell and Molecular Genetics. 17, 2, p. 117-136 20 p.

Research output: Contribution to journalArticle

38 Scopus citations

Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast

Campbell, M. J., Baehner, F., O’Meara, T., Ojukwu, E., Han, B., Mukhtar, R., Tandon, V., Endicott, M., Zhu, Z., Wong, J., Krings, G., Au, A., Gray, J. W. & Esserman, L., Jan 1 2017, In : Breast Cancer Research and Treatment. 161, 1, p. 17-28 12 p.

Research output: Contribution to journalArticle

40 Scopus citations

Chemotherapy response and recurrence-free survival in Neoadjuvant breast cancer depends on biomarker profiles: Results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)

Esserman, L. J., Berry, D. A., Cheang, M. C. U., Yau, C., Perou, C. M., Carey, L., De Michele, A., Gray, J. W., Conway-Dorsey, K., Lenburg, M. E., Buxton, M. B., Davis, S. E., Van't Veer, L. J., Hudis, C., Chin, K., Wolf, D., Krontiras, H., Montgomery, L., Tripathy, D., Lehman, C. & 14 others, Liu, M. C., Olopade, O. I., Rugo, H. S., Carpenter, J. T., Livasy, C., Dressler, L., Chhieng, D., Singh, B., Mies, C., Rabban, J., Chen, Y. Y., Giri, D., Au, A. & Hylton, N., Apr 1 2012, In : Breast Cancer Research and Treatment. 132, 3, p. 1049-1062 14 p.

Research output: Contribution to journalArticle

208 Scopus citations

Chromosomal localization of the γ-glutamyl carboxylase gene at 2p12

Kuo, W. L., Stafford, D. W., Cruces, J., Gray, J. & Jesú, S., Jan 1 1995, In : Genomics. 25, 3, p. 746-748 3 p.

Research output: Contribution to journalArticle

29 Scopus citations

Chromosomal reassignment: Yacs containing both yes1 and thymidylate synthase map to the short arm of chromosome 18

Silverman, G. A., Kuo, W. L., Taillon-Miller, P. & Gray, J. W., Feb 1993, In : Genomics. 15, 2, p. 442-445 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Chromosome arm 20q gains and other genomic alterations in colorectal cancer metastatic to liver, as analyzed by comparative genomic hybridization and fluorescence in situ hybridization

Korn, W. M., Yasutake, T., Kuo, W. L., Warren, R. S., Collins, C., Tomita, M., Gray, J. & Waldman, F. M., Jun 1 1999, In : Genes Chromosomes and Cancer. 25, 2, p. 82-90 9 p.

Research output: Contribution to journalArticle

117 Scopus citations

Chromosome heteromorphism quantified by high-resolution bivariate flow karyotyping

Trask, B., Van den Engh, G., Mayall, B. & Gray, J. W., Jan 1 1989, In : American Journal of Human Genetics. 45, 5, p. 739-752 14 p.

Research output: Contribution to journalArticle

57 Scopus citations

Chromosome measurement and sorting by flow systems

Gray, J. W., Carrano, A. V., Steinmetz, L. L., Van Dilla, M. A., Moore IInd, D. H., Mayall, B. H. & Mendelsohn, M. L., 1975, In : Proceedings of the National Academy of Sciences of the United States of America. 72, 4, p. 1231-1234 4 p.

Research output: Contribution to journalArticle

139 Scopus citations

Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer

Butler, T. M., Boniface, C. T., Johnson-Camacho, K., Tabatabaei, S., Melendez, D., Kelley, T., Gray, J., Corless, C. L. & Spellman, P. T., 2019, In : Cold Spring Harbor Molecular Case Studies. 5, 2, a003772.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Clinical applications of fluorescence in situ hybridization

Tkachuk, D. C., Pinkel, D., Kuo, W. L., Weier, H. U. & Gray, J. W., Apr 1991, In : Genetic Analysis: Biomolecular Engineering. 8, 2, p. 67-74 8 p.

Research output: Contribution to journalArticle

81 Scopus citations

Clinical applications of the bromodeoxyuridine/DNA assay

Waldman, F. M., Dolbeare, F. & Gray, J., 1988, In : Cytometry. 9, 3 S, p. 65-72 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cloning, mapping, and in vivo localization of a human member of the PKCI-1 protein family (PRKCNH1)

Brzoska, P. M., Chen, H., Levin, N. A., Kuo, W. L., Collins, C., Fu, K. K., Gray, J. W. & Christman, M. F., Aug 15 1996, In : Genomics. 36, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Cloning and Characterization of EagI YACs from Human Chromosome 21

Gingrich, J. C., Lowry, S. R., Kuo, W. L., Gray, J., Smith, C. L. & Cantori, C. R., Jan 1993, In : Genomics. 15, 1, p. 228-230 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Cloning of genomic sequences from the human Y chromosome after purification by dual beam flow sorting

Müller, C. R., Davies, K. E., Cremer, C., Rappold, G., Gray, J. W. & Ropers, H. H., Aug 1 1983, In : Human genetics. 64, 2, p. 110-115 6 p.

Research output: Contribution to journalArticle

13 Scopus citations