• 66999 Citations
  • 112 h-Index
1971 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Article

Combating subclonal evolution of resistant cancer phenotypes

Brady, S. W., McQuerry, J. A., Qiao, Y., Piccolo, S. R., Shrestha, G., Jenkins, D. F., Layer, R. M., Pedersen, B. S., Miller, R. H., Esch, A., Selitsky, S. R., Parker, J. S., Anderson, L. A., Dalley, B. K., Factor, R. E., Reddy, C. B., Boltax, J. P., Li, D. Y., Moos, P. J., Gray, J. W. & 8 others, Heiser, L. M., Buys, S. S., Cohen, A. L., Johnson, W. E., Quinlan, A. R., Marth, G., Werner, T. L. & Bild, A. H., Dec 1 2017, In : Nature communications. 8, 1, 1231.

Research output: Contribution to journalArticle

31 Scopus citations

Combinatorial Microenvironments Impose a Continuum of Cellular Responses to a Single Pathway-Targeted Anti-cancer Compound

Lin, C. H., Jokela, T., Gray, J. & LaBarge, M. A., Oct 10 2017, In : Cell Reports. 21, 2, p. 533-545 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts

Hodgson, J. G., Yeh, R. F., Ray, A., Wang, N. J., Smirnov, I., Yu, M., Hariono, S., Silber, J., Feiler, H. S., Gray, J. W., Spellman, P. T., Vandenberg, S. R., Berger, M. S. & James, C. D., Oct 1 2009, In : Neuro-Oncology. 11, 5, p. 477-487 11 p.

Research output: Contribution to journalArticle

87 Scopus citations

Comparative genomic hybridization: A rapid new method for detecting and mapping DNA amplification in tumors

Kallioniemi, O. P., Kallioniemi, A., Sudar, D., Rutovitz, D., Gray, J. W., Waldman, F. & Pinkel, D., Dec 1 1993, In : Seminars in Cancer Biology. 4, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

202 Scopus citations

Comparative genomic hybridization.

DeVries, S., Gray, J. W., Pinkel, D., Waldman, F. M. & Sudar, D., May 2001, In : Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.]. Chapter 4, p. Unit4.6

Research output: Contribution to journalArticle

2 Scopus citations

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

Kallioniemi, A., Kallioniemi, O. P., Sudar, D., Rutovitz, D., Gray, J. W., Waldman, F. & Pinkel, D., Jan 1 1992, In : Science. 258, 5083, p. 818-821 4 p.

Research output: Contribution to journalArticle

2745 Scopus citations

Comprehensive genome sequence analysis of a breast cancer amplicon

Collins, C., Volik, S., Kowbel, D., Ginzinger, D., Ylstra, B., Cloutier, T., Hawkins, T., Predki, P., Martin, C., Wernick, M., Kuo, W. L., Alberts, A. & Gray, J. W., Sep 22 2001, In : Genome Research. 11, 6, p. 1034-1042 9 p.

Research output: Contribution to journalArticle

74 Scopus citations

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

McLendon, R., Friedman, A., Bigner, D., Van Meir, E. G., Brat, D. J., Mastrogianakis, G. M., Olson, J. J., Mikkelsen, T., Lehman, N., Aldape, K., Yung, W. K. A., Bogler, O., Weinstein, J. N., VandenBerg, S., Berger, M., Prados, M., Muzny, D., Morgan, M., Scherer, S., Sabo, A. & 211 others, Nazareth, L., Lewis, L., Hall, O., Zhu, Y., Ren, Y., Alvi, O., Yao, J., Hawes, A., Jhangiani, S., Fowler, G., San Lucas, A., Kovar, C., Cree, A., Dinh, H., Santibanez, J., Joshi, V., Gonzalez-Garay, M. L., Miller, C. A., Milosavljevic, A., Donehower, L., Wheeler, D. A., Gibbs, R. A., Cibulskis, K., Sougnez, C., Fennell, T., Mahan, S., Wilkinson, J., Ziaugra, L., Onofrio, R., Bloom, T., Nicol, R., Ardlie, K., Baldwin, J., Gabriel, S., Lander, E. S., Ding, L., Fulton, R. S., McLellan, M. D., Wallis, J., Larson, D. E., Shi, X., Abbott, R., Fulton, L., Chen, K., Koboldt, D. C., Wendl, M. C., Meyer, R., Tang, Y., Lin, L., Osborne, J. R., Dunford-Shore, B. H., Miner, T. L., Delehaunty, K., Markovic, C., Swift, G., Courtney, W., Pohl, C., Abbott, S., Hawkins, A., Leong, S., Haipek, C., Schmidt, H., Wiechert, M., Vickery, T., Scott, S., Dooling, D. J., Chinwalla, A., Weinstock, G. M., Mardis, E. R., Wilson, R. K., Getz, G., Winckler, W., Verhaak, R. G. W., Lawrence, M. S., O'Kelly, M., Robinson, J., Alexe, G., Beroukhim, R., Carter, S., Chiang, D., Gould, J., Gupta, S., Korn, J., Mermel, C., Mesirov, J., Monti, S., Nguyen, H., Parkin, M., Reich, M., Stransky, N., Weir, B. A., Garraway, L., Golub, T., Meyerson, M., Chin, L., Protopopov, A., Zhang, J., Perna, I., Aronson, S., Sathiamoorthy, N., Ren, G., Yao, J., Wiedemeyer, W. R., Kim, H., Sek, W. K., Xiao, Y., Kohane, I. S., Seidman, J., Park, P. J., Kucherlapati, R., Laird, P. W., Cope, L., Herman, J. G., Weisenberger, D. J., Pan, F., Van Den Berg, D., Van Neste, L., Joo, M. Y., Schuebel, K. E., Baylin, S. B., Absher, D. M., Li, J. Z., Southwick, A., Brady, S., Aggarwal, A., Chung, T., Sherlock, G., Brooks, J. D., Myers, R. M., Spellman, P. T., Purdom, E., Jakkula, L. R., Lapuk, A. V., Marr, H., Dorton, S., Yoon, G. C., Han, J., Ray, A., Wang, V., Durinck, S., Robinson, M., Wang, N. J., Vranizan, K., Peng, V., Van Name, E., Fontenay, G. V., Ngai, J., Conboy, J. G., Parvin, B., Feiler, H. S., Speed, T. P., Gray, J. W., Brennan, C., Socci, N. D., Olshen, A., Taylor, B. S., Lash, A., Schultz, N., Reva, B., Antipin, Y., Stukalov, A., Gross, B., Cerami, E., Wei, Q. W., Qin, L. X., Seshan, V. E., Villafania, L., Cavatore, M., Borsu, L., Viale, A., Gerald, W., Sander, C., Ladanyi, M., Perou, C. M., Hayes, D. N., Topal, M. D., Hoadley, K. A., Qi, Y., Balu, S., Shi, Y., Wu, J., Penny, R., Bittner, M., Shelton, T., Lenkiewicz, E., Morris, S., Beasley, D., Sanders, S., Kahn, A., Sfeir, R., Chen, J., Nassau, D., Feng, L., Hickey, E., Barker, A., Gerhard, D. S., Vockley, J., Compton, C., Vaught, J., Fielding, P., Ferguson, M. L., Schaefer, C., Zhang, J., Madhavan, S., Buetow, K. H., Collins, F., Good, P., Guyer, M., Ozenberger, B., Peterson, J. & Thomson, E., Oct 23 2008, In : Nature. 455, 7216, p. 1061-1068 8 p.

Research output: Contribution to journalArticle

4666 Scopus citations

Comprehensive sequence analysis of a human 20q13.2 cancer amplicon

Collins, C., Volik, S., Kowbel, D., Wernick, M., Hawkins, T., Predki, P., Kuo, W. L. & Gray, J., 2001, In : Nature Genetics. 27, 4S, p. 48 1 p.

Research output: Contribution to journalArticle

Computational BAC Clone Contig Assembly for Comprehensive Genome Analysis

Lapuk, A., Volik, S., Vincent, R., Chin, K., Kuo, W. L., De Jong, P., Collins, C. & Gray, J. W., May 1 2004, In : Genes Chromosomes and Cancer. 40, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Computer image analysis of comparative genomic hybridization

Piper, J., Rutovitz, D., Sudar, D., Kallioniemi, A., Kallioniemi, OP. P., Waldman, F. M., Gray, J. W. & Pinkel, D., Jan 1 1995, In : Cytometry. 19, 1, p. 10-26 17 p.

Research output: Contribution to journalArticle

235 Scopus citations

Construction and characterization of a yeast artificial chromosome library containing 1.5 equivalents of human chromosome 21

Potier, M. C., Kuo, W. L., Dutriaux, A., Gray, J. & Goedert, M., Oct 1992, In : Genomics. 14, 2, p. 481-483 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

Construction and characterization of plasmid libraries enriched in sequences from single human chromosomes

Collins, C., Kuo, W. L., Segraves, R., Fuscoe, J., Pinkel, D. & Gray, J. W., Dec 1991, In : Genomics. 11, 4, p. 997-1006 10 p.

Research output: Contribution to journalArticle

212 Scopus citations

Construction of human chromosome-specific DNA libraries from flow-sorted chromosomes

Deaven, L. L., van Dilla, M. A., Bartholdi, M. F., Carrano, A. V., Cram, L. S., Fuscoe, J. C., Gray, J. W., Hildebrand, C. E., Moyzis, R. K. & Perlman, J., Dec 1 1986, In : Cold Spring Harbor symposia on quantitative biology. 51, 1, p. 159-167 9 p.

Research output: Contribution to journalArticle

94 Scopus citations

Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

Hill, S. M., Nesser, N. K., Johnson-Camacho, K., Jeffress, M., Johnson, A., Boniface, C., Spencer, S. E. F., Lu, Y., Heiser, L. M., Lawrence, Y., Pande, N. T., Korkola, J. E., Gray, J. W., Mills, G. B., Mukherjee, S. & Spellman, P. T., Jan 25 2017, In : Cell Systems. 4, 1, p. 73-83.e10

Research output: Contribution to journalArticle

12 Scopus citations

Copy number aberrations in mouse breast tumors reveal loci and genes important in tumorigenic receptor tyrosine kinase signaling

Hodgson, J. G., Malek, T., Bornstein, S., Hariono, S., Ginzinger, D. G., Muller, W. J. & Gray, J. W., Nov 1 2005, In : Cancer Research. 65, 21, p. 9695-9704 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Copy Number Gain of hsa-miR-569 at 3q26.2 Leads to Loss of TP53INP1 and Aggressiveness of Epithelial Cancers

Chaluvally-Raghavan, P., Zhang, F., Pradeep, S., Hamilton, M. P., Zhao, X., Rupaimoole, R., Moss, T., Lu, Y., Yu, S., Pecot, C. V., Aure, M. R., Peuget, S., Rodriguez-Aguayo, C., Han, H. D., Zhang, D., Venkatanarayan, A., Krohn, M., Kristensen, V. N., Gagea, M., Ram, P. & 11 others, Liu, W., Lopez-Berestein, G., Lorenzi, P. L., Børresen-Dale, A. L., Chin, K., Gray, J., Dusetti, N. J., McGuire, S. E., Flores, E. R., Sood, A. K. & Mills, G. B., Dec 8 2014, In : Cancer Cell. 26, 6, p. 863-879 17 p.

Research output: Contribution to journalArticle

31 Scopus citations

CpG island shore methylation regulates caveolin-1 expression in breast cancer

Rao, X., Evans, J., Chae, H., Pilrose, J., Kim, S., Yan, P., Huang, R. L., Lai, H. C., Lin, H., Liu, Y., Miller, D., Rhee, J. K., Huang, Y. W., Gu, F., Gray, J. W., Huang, T. M. & Nephew, K. P., Sep 19 2013, In : Oncogene. 32, 38, p. 4519-4528 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib

Daemen, A., Wolf, D. M., Korkola, J. E., Griffith, O. L., Frankum, J. R., Brough, R., Jakkula, L. R., Wang, N. J., Natrajan, R., Reis-Filho, J. S., Lord, C. J., Ashworth, A., Spellman, P. T., Gray, J. W. & Van'T Veer, L. J., Sep 1 2012, In : Breast Cancer Research and Treatment. 135, 2, p. 505-517 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

Crosstalk between Aurora-A and p53: Frequent Deletion or Downregulation of Aurora-A in Tumors from p53 Null Mice

Mao, J. H., Wu, D., Perez-Losada, J., Jiang, T., Li, Q., Neve, R. M., Gray, J. W., Cai, W. W. & Balmain, A., Feb 13 2007, In : Cancer Cell. 11, 2, p. 161-173 13 p.

Research output: Contribution to journalArticle

57 Scopus citations

C-Src modulates estrogen-induced stress and apoptosis in estrogen-deprived breast cancer cells

Fan, P., Griffith, O. L., Agboke, F. A., Anur, P., Zou, X., McDaniel, R. E., Creswell, K., Kim, S. H., Katzenellenbogen, J. A., Gray, J. W. & Jordan, V. C., Jul 15 2013, In : Cancer Research. 73, 14, p. 4510-4520 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression

Wang, Y., Wen, M., Kwon, Y., Xu, Y., Liu, Y., Zhang, P., He, X., Wang, Q., Huang, Y., Jen, K. Y., Labarge, M. A., You, L., Kogan, S. C., Gray, J. W., Mao, J. H. & Wei, G., Jan 15 2014, In : Cancer Research. 74, 2, p. 520-531 12 p.

Research output: Contribution to journalArticle

142 Scopus citations

Current development of targeted oligonucleotide-based cancer therapies: Perspective on HER2-positive breast cancer treatment

Ngamcherdtrakul, W., Castro, D. J., Gu, S., Morry, J., Reda, M., Gray, J. & Yantasee, W., Apr 1 2016, In : Cancer Treatment Reviews. 45, p. 19-29 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
15 Scopus citations

Cyclic AMP, a nonessential regulator of the cell cycle

Coffino, P., Gray, J. W. & Tomkins, G. M., Jan 1 1975, In : Proceedings of the National Academy of Sciences of the United States of America. 72, 3, p. 878-882 5 p.

Research output: Contribution to journalArticle

Open Access
93 Scopus citations
1 Scopus citations

Cytochemical studies of metaphase chromosomes by flow cytometry

Langlois, R. G., Carrano, A. V., Gray, J. W. & Van Dilla, M. A., Mar 1 1980, In : Chromosoma. 77, 3, p. 229-251 23 p.

Research output: Contribution to journalArticle

62 Scopus citations

Cytochemistry for bromodeoxyuridine/DNA analysis: Stoichiometry and sensitivity

Dolbeare, F., Beisker, W., Pallavicini, M. G., Vanderlaan, M. & Gray, J. W., Nov 1985, In : Cytometry. 6, 6, p. 521-530 10 p.

Research output: Contribution to journalArticle

131 Scopus citations

Cytogenetic analysis by in situ hybridization with fluorescently labeled nucleic acid probes

Pinkel, D., Gray, J. W., Trask, B., van den Engh, G., Fuscoe, J. & van Dekken, H., Dec 1 1986, In : Cold Spring Harbor symposia on quantitative biology. 51, 1, p. 151-157 7 p.

Research output: Contribution to journalArticle

224 Scopus citations

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization

Pinkel, D., Straume, T. & Gray, J. W., Jan 1 1986, In : Proceedings of the National Academy of Sciences of the United States of America. 83, 9, p. 2934-2938 5 p.

Research output: Contribution to journalArticle

Open Access
2758 Scopus citations

Cytogenetic profiling using fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH)

Thompson, C. T. & Gray, J. W., 1993, In : Journal of cellular biochemistry. 53, S17G, p. 139-143 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Cytokinetic characterization of the response of the KHT tumor to ara-C

Pallavicini, M. G., Folstad, L. J. & Gray, J. W., Jan 1 1980, In : Basic and Applied Histochemistry. 24, 4, 1 p.

Research output: Contribution to journalArticle

Cytokinetic properties of asynchronous and cytosine arabinoside perturbed murine tumors measured by simultaneous bromodeoxyuridine/DNA analyses

Pallavicini, M. G., Summers, L. J., Dolbeare, F. D. & Gray, J. W., Nov 1985, In : Cytometry. 6, 6, p. 602-610 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Decoding the fine-scale structure of a breast cancer genome and transcriptome

Volik, S., Raphael, B. J., Huang, G., Stratton, M. R., Bignel, G., Murnane, J., Brebner, J. H., Bajsarowicz, K., Paris, P. L., Tao, Q., Kowbel, D., Lapuk, A., Shagin, D. A., Shagina, I. A., Gray, J. W., Cheng, J. F., De Jong, P. J., Pevzner, P. & Collins, C., Mar 1 2006, In : Genome Research. 16, 3, p. 394-404 11 p.

Research output: Contribution to journalArticle

49 Scopus citations

Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer

Korkola, J. E., Collisson, E. A., Heiser, L., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N. J., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Feiler, H., Lu, Y., Mills, G. B., Spellman, P. T., Tomlin, C. & 3 others, Mukherjee, S., Gray, J. W. & Jakkula, L., Jul 16 2015, In : PloS one. 10, 7, e0133219.

Research output: Contribution to journalArticle

11 Scopus citations

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

Donehower, L. A., Godley, L. A., Aldaz, C. M., Pyle, R., Shi, Y. P., Pinkel, D., Gray, J., Bradley, A., Medina, D. & Varmus, H. E., Apr 1 1995, In : Genes and Development. 9, 7, p. 882-895 14 p.

Research output: Contribution to journalArticle

Open Access
244 Scopus citations

Defining the steps in a multistep mouse model for mammary carcinogenesis

Varmus, H. E., Godley, L. A., Roy, S., Taylor, I. C. A., Yuschenkoff, L., Shi -, Y. P., Pinkel, D., Gray, J., Pyle, R., Aldaz, C. M., Bradley, A., Medina, D. & Donehower, L. A., Jan 1 1994, In : Cold Spring Harbor symposia on quantitative biology. 59, p. 491-499 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer

Climent, J., Dimitrow, P., Fridlyand, J., Palacios, J., Siebert, R., Albertson, D. G., Gray, J. W., Pinkel, D., Lluch, A. & Martinez-Climent, J. A., Jan 15 2007, In : Cancer Research. 67, 2, p. 818-826 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Deletion of Chromosome 17p Loci in Breast Cancer Cells Detected by Fluorescence in Situ Hybridization

Matsumura, K., Kallioniemi, A., Kallioniemi, O., Chen, L., Smith, H. S., Pinkel, D., Gray, J. & Waldman, F. M., Jun 1992, In : Cancer Research. 52, 12, p. 3474-3477 4 p.

Research output: Contribution to journalArticle

107 Scopus citations
93 Scopus citations

Derivative domain fitting: A new method for resolving a mixture of normal distributions in the presence of a contaminating background

Moore, D. H. & Gray, J. W., 1993, In : Cytometry. 14, 5, p. 510-518 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Design considerations for array CGH to oligonucleotide arrays

Baldocchi, R. A., Glynne, R. J., Chin, K., Kowbel, D., Collins, C., Mack, D. H. & Gray, J. W., Oct 1 2005, In : Cytometry Part A. 67, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

Kallioniemi, A., Kallioniemi, O. P., Piper, J., Tanner, M., Stokke, T., Chen, L., Smith, H. S., Pinkel, D., Gray, J. W. & Waldman, F. M., Mar 15 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 6, p. 2156-2160 5 p.

Research output: Contribution to journalArticle

Open Access
677 Scopus citations

Detection of a human chromosomal translocation t(8;9) in a baby with multiple malformations using two‐color fluorescence in situ hybridization

Sasaki, K., Pinkel, D., Tsukahara, M., Murano, I. & Gray, J. W., Feb 1994, In : Pathology International. 44, 2, p. 145-150 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Detection of aneuploidy involving chromosomes 13, 18, or 21, by fluorescence in situ hybridization (FISH) to interphase and metaphase amniocytes

Kuo, W. L., Tenijn, H., Segraves, R., Pinkel, D., Golbus, M. S. & Gray, J., Aug 29 1991, In : American Journal of Human Genetics. 49, 1, p. 112-119 8 p.

Research output: Contribution to journalArticle

113 Scopus citations

Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization

Tkachuk, D. C., Westbrook, C. A., Andreeff, M., Donlon, T. A., Cleary, M. L., Suryanarayan, K., Homge, M., Redner, A., Gray, J. & Pinkel, D., Jan 1 1990, In : Science. 250, 4980, p. 559-562 4 p.

Research output: Contribution to journalArticle

330 Scopus citations

Detection of cytosine arabinoside resistant cells at low frequency using the bromodeoxyuridine/DNA assay

Waldman, F. M., Dolbeare, F. & Gray, J. W., Nov 1985, In : Cytometry. 6, 6, p. 657-662 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization

Kallioniemi, A., Kallioniemi, O. P., Waidman, F. M., Chen, L. C., Yu, L. C., Fung, Y. K. T., Smith, H. S., Pinkel, D. & Gray, J. W., Jan 1 1992, In : Cytogenetic and Genome Research. 60, 3-4, p. 190-193 4 p.

Research output: Contribution to journalArticle

45 Scopus citations

Dicentric chromosome frequency analysis using slit‐scan flow cytometry

Lucas, J. N., Mullikin, J. C. & Gray, J. W., 1991, In : Cytometry. 12, 4, p. 316-322 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Dicer, Drosha, and outcomes in patients with ovarian cancer

Merritt, W. M., Lin, Y. G., Han, L. Y., Kamat, A. A., Spannuth, W. A., Schmandt, R., Urbauer, D., Pennacchio, L. A., Cheng, J. F., Nick, A. M., Deavers, M. T., Mourad-Zeidan, A., Wang, H., Mueller, P., Lenburg, M. E., Gray, J. W., Mok, S., Birrer, M. J., Lopez-Berestein, G., Coleman, R. L. & 2 others, Bar-Eli, M. & Sood, A. K., Dec 18 2008, In : New England Journal of Medicine. 359, 25, p. 2641-2650 10 p.

Research output: Contribution to journalArticle

529 Scopus citations