• 67731 Citations
  • 113 h-Index
1971 …2020

Research output per year

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Research Output

Separation and analysis of human chromosomes by combined velocity sedimentation and flow sorting applying single‐ and dual‐laser flow cytometry

Collard, J. G., Philippus, E., Tulp, A., Lebo, R. V. & Gray, J. W., Jan 1984, In : Cytometry. 5, 1, p. 9-19 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

SHIFT: Speedy histopathological-To-immunofluorescent translation of whole slide images using conditional generative adversarial networks

Burlingame, E. A., Margolin, A., Gray, J. & Chang, Y. H., Jan 1 2018, Medical Imaging 2018: Digital Pathology. SPIE, Vol. 10581. 1058105

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Signal removal methods for highly multiplexed immunofluorescent staining using antibody conjugated oligonucleotides

McMahon, N., Jones, J., Eng, J., Kwon, S., Chang, Y. H., Thibault, G., Chin, K., Nederlof, M., Gray, J. & Gibbs, S. L., Jan 1 2019, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVII. Leary, J. F., Tarnok, A. & Farkas, D. L. (eds.). SPIE, 108810X. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10881).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Simultaneous Multicolor Single-Molecule Tracking with Single-Laser Excitation via Spectral Imaging

Huang, T., Phelps, C., Wang, J., Lin, L. J., Bittel, A., Scott, Z., Jacques, S., Gibbs, S., Gray, J. & Nan, X., Jan 23 2018, In : Biophysical Journal. 114, 2, p. 301-310 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling

Nan, X., Collisson, E. A., Lewis, S., Huang, J., Tamgüney, T. M., Liphardt, J. T., McCormick, F., Gray, J. W. & Chu, S., Nov 12 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 46, p. 18519-18524 6 p.

Research output: Contribution to journalArticle

91 Scopus citations

Slit-scan cytometry of mammalian chromosomes

Gray, J. W., Peters, D. & Merrill, J. T., Jan 1 1979, In : Journal of Histochemistry and Cytochemistry. 27, 1, p. 441-444 4 p.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations

Slit-scan flow cytometry: analysis of Chinese hamster M3-1 chromosomes

Gray, J. W., Lucas, J. & Pinkel, D., Jan 1 1981, In : Acta Pathologica et Microbiologica Scandinavica - Section A Pathology. 89, Suppl.274, p. 249-255 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Solid tumor response to two doses of Ara-C: Cell survival prediction based on single dose cytokinetic data

Pallavicini, M. G., Folstad, L. J. & Gray, J. W., Jan 1 1982, In : Cell and Tissue Kinetics. 15, 1, p. 109-110 2 p.

Research output: Contribution to journalArticle

Sparse combinatorial inference with an application in cancer biology

Mukherjee, S., Pelech, S., Neve, R. M., Kuo, W. L., Ziyad, S., Spellman, P. T., Gray, J. W. & Speed, T. P., Jan 1 2009, In : Bioinformatics. 25, 2, p. 265-271 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Sparse multitask regression for identifying common mechanism of response to therapeutic targets

Zhang, K., Gray, J. W. & Parvin, B., Jun 1 2010, In : Bioinformatics. 26, 12, p. i97-i105 btq181.

Research output: Contribution to journalArticle

21 Scopus citations

Specific keynote: genome copy number abnormalities in ovarian cancer.

Gray, J. W., Suzuki, S., Kuo, W. L., Polikoff, D., Deavers, M., Smith-McCune, K., Berchuck, A., Pinkel, D., Albertson, D. & Mills, G. B., Jan 2003, In : Gynecologic oncology. 88, 1 Pt 2, p. S16-21; discussion S22-24

Research output: Contribution to journalReview article

35 Scopus citations

Specific keynote: molecular therapeutics in ovarian cancer.

Mills, G. B., Fang, X., Lu, Y., Hasegawa, Y., Eder, A., Tanyi, J., Tabassam, F. H., Mao, M., Wang, H., Cheng, K. W., Nakayama, Y., Kuo, W., Erickson, J., Gershenson, D., Kohn, E. C., Jaffe, R., Bast, R. C. & Gray, J., Jan 2003, In : Gynecologic oncology. 88, 1 Pt 2, p. S88-92; discussion S93-96

Research output: Contribution to journalReview article

18 Scopus citations

Spectral decomposition of signaling networks

Parvin, B., Ghosh, N., Heiser, L., Knapp, M., Talcott, C., Laderoute, K., Gray, J. & Spellman, P., 2007, 2007 IEEE Symposium on Computational Intelligence and Bioinformatics and Computational Biology, CIBCB 2007. IEEE Computer Society, p. 76-81 6 p. 4221207. (2007 IEEE Symposium on Computational Intelligence and Bioinformatics and Computational Biology, CIBCB 2007).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Stabilization of chromosomes by DNA intercalators for flow karyotyping and identification by banding of isolated chromosomes

Aten, J. A., Buys, C. H. C. M., van der Veen, A. Y., Mesa, J. R., Yu, L. C., Gray, J. W., Osinga, J. & Stap, J., Jul 1 1987, In : Histochemistry. 87, 4, p. 359-366 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Statement on Use of DNA Testing for Presymptomatic Identification of Cancer Risk

Collins, F. S., Benjamin, L. J., Botstein, D., Cox, J. R., Davidson, N., Gray, J. W., Housman, D. E., Holtzman, N., Jamison, K. R., Rothstein, R., Smith, D. C., Smith, L. M., Spence, M. A. & Tilghman, S. M., Mar 9 1994, In : JAMA: The Journal of the American Medical Association. 271, 10, 1 p.

Research output: Contribution to journalArticle

131 Scopus citations

Stromal-epithelial interactions in the progression of ovarian cancer: Influence and source of tumor stromal cells

Parrott, J. A., Nilsson, E., Mosher, R., Magrane, G., Albertson, D., Pinkel, D., Gray, J. W. & Skinner, M. K., Apr 25 2001, In : Molecular and Cellular Endocrinology. 175, 1-2, p. 29-39 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

Structural Chromosome Analysis by Whole Chromosome Painting for Assessment of Radiation-Induced Genetic Damage

Gray, J. W., Pinkel, D., Lucas, J. N. & Awa, A., Jan 1 1992, In : Journal of radiation research. 33, p. 80-86 7 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Subregional localization of 21 chromosome 7-specific expressed sequence tags (ESTs) by FISH using newly identified YACs and P1s

Morton, S. M., Veile, R. A., Helms, C., Lee, M., Kuo, W. L., Gray, J. & Donis-Keller, H., Dec 15 1997, In : Genomics. 46, 3, p. 491-494 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Subtype and pathway specific responses to anticancer compounds in breast cancer

Heiser, L. M., Sadanandam, A., Kuo, W. L., Benz, S. C., Goldstein, T. C., Ng, S., Gibb, W. J., Wang, N. J., Ziyad, S., Tong, F., Bayani, N., Hu, Z., Billig, J. I., Dueregger, A., Lewis, S., Jakkula, L., Korkola, J. E., Durinck, S., Pepin, F., Guan, Y. & 23 others, Purdom, E., Neuvial, P., Bengtsson, H., Wood, K. W., Smith, P. G., Vassilev, L. T., Hennessy, B. T., Greshock, J., Bachman, K. E., Hardwicke, M. A., Park, J. W., Marton, L. J., Wolf, D. M., Collisson, E. A., Neve, R. M., Mills, G. B., Speed, T. P., Feiler, H. S., Richard, F. W., Haussler, D., Stuart, J. M., Gray, J. W. & Spellman, P. T., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 2724-2729 6 p.

Research output: Contribution to journalArticle

275 Scopus citations

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

Collisson, E. A., Sadanandam, A., Olson, P., Gibb, W. J., Truitt, M., Gu, S., Cooc, J., Weinkle, J., Kim, G. E., Jakkula, L., Feiler, H. S., Ko, A. H., Olshen, A. B., Danenberg, K. L., Tempero, M. A., Spellman, P. T., Hanahan, D. & Gray, J. W., Apr 2011, In : Nature medicine. 17, 4, p. 500-503 4 p.

Research output: Contribution to journalArticle

627 Scopus citations

Synthesis of Y chromosome-specific labeled DNA probes by in vitro DNA amplification

Weier, H. U. G., Segraves, R., Pinkel, D. & Gray, J. W., Jan 1 1990, In : Journal of Histochemistry and Cytochemistry. 38, 3, p. 421-426 6 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Systems biology in cancer research: genomics to cellomics.

Stilwell, J. L., Guan, Y., Neve, R. M. & Gray, J. W., 2007, In : Methods in molecular biology (Clifton, N.J.). 356, p. 353-365 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Targeted treatment of metastatic breast cancer by PLK1 siRNA delivered by an antioxidant nanoparticle platform

Morry, J., Ngamcherdtrakul, W., Gu, S., Reda, M., Castro, D. J., Sangvanich, T., Gray, J. W. & Yantasee, W., Apr 2017, In : Molecular cancer therapeutics. 16, 4, p. 763-772 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Targeting mitochondria in cancer therapy could provide a basis for the selective anticancer activity

Rozanov, D., Cheltsov, A., Nilsen, A., Boniface, C., Forquer, I., Korkola, J., Gray, J., Tyner, J., Tognon, C. E., Mills, G. B. & Spellman, P., Mar 2019, In : PloS one. 14, 3, e0205623.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Targeting the mevalonate pathway to overcome acquired anti-HER2 treatment resistance in breast cancer

Sethunath, V., Hu, H., De Angelis, C., Veeraraghavan, J., Qin, L., Wang, N., Simon, L. M., Wang, T., Fu, X., Nardone, A., Pereira, R., Nanda, S., Griffith, O. L., Tsimelzon, A., Shaw, C., Chamness, G. C., Reis-Filho, J. S., Weigelt, B., Heiser, L. M., Hilsenbeck, S. G. & 5 others, Huang, S., Rimawi, M. F., Gray, J. W., Osborne, C. K. & Schiff, R., 2019, In : Molecular Cancer Research. 17, 11, p. 2318-2330 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Targeting uPAR with antagonistic recombinant human antibodies in aggressive breast cancer

Le Beau, A. M., Duriseti, S., Murphy, S. T., Pepin, F., Hann, B., Gray, J. W., Van Brocklin, H. F. & Craik, C. S., Apr 1 2013, In : Cancer Research. 73, 7, p. 2070-2081 12 p.

Research output: Contribution to journalArticle

45 Scopus citations

TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines

Fan, W., Huang, X., Chen, C., Gray, J. & Huang, T., Aug 1 2004, In : Cancer Research. 64, 15, p. 5132-5139 8 p.

Research output: Contribution to journalArticle

89 Scopus citations

Technical approaches for efficient, high precision nucleic acid analysis using DNA microarrays

Pinkel, D., Hamilton, G., Brown, N., Segraves, R., Huey, B., Snijders, A., Blackwood, S., Hindle, K., Law, S., Gray, J., Jain, A., Hanson, J., Nordmeyer, R. & Albertson, D., Jan 1 2002, In : Proceedings of SPIE-The International Society for Optical Engineering. 4626, p. 82-88 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Temporal dissection of tumorigenesis in primary cancers

Durinck, S., Ho, C., Wang, N., Liao, W., Jakkula, L. R., Collisson, E. A., Pons, J., Chan, S. W., Lam, E. T., Chu, C., Park, K., Hong, S. W., Hur, J. S., Huh, N., Neuhaus, I. M., Yu, S. S., Grekin, R. C., Mauro, T. M., Cleaver, J. E., Kwok, P. Y. & 12 others, LeBoit, P. E., Getz, G., Cibulskis, K., Aster, J. C., Huang, H., Purdom, E., Li, J., Bolund, L., Arron, S. T., Gray, J. W., Spellman, P. T. & Cho, R. J., Jun 29 2011, In : Cancer discovery. 1, 2, p. 137-143 7 p.

Research output: Contribution to journalArticle

152 Scopus citations

The analysis and interpretation of DNA distributions measured by flow cytometry

Dean, P. N., Gray, J. W. & Dolbeare, F. A., Nov 1982, In : Cytometry. 3, 3, p. 188-195 8 p.

Research output: Contribution to journalArticle

81 Scopus citations

The binding kinetics and interaction of DNA fluorochromes used in the analysis of nuclei and chromosomes by flow cytometry

van den Engh, G. J., Trask, B. J. & Gray, J. W., Jul 1 1986, In : Histochemistry. 84, 4-6, p. 501-508 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

The consensus molecular subtypes of colorectal cancer

Guinney, J., Dienstmann, R., Wang, X., De Reyniès, A., Schlicker, A., Soneson, C., Marisa, L., Roepman, P., Nyamundanda, G., Angelino, P., Bot, B. M., Morris, J. S., Simon, I. M., Gerster, S., Fessler, E., De Sousa .E Melo, F., Missiaglia, E., Ramay, H., Barras, D., Homicsko, K. & 20 others, Maru, D., Manyam, G. C., Broom, B., Boige, V., Perez-Villamil, B., Laderas, T., Salazar, R., Gray, J. W., Hanahan, D., Tabernero, J., Bernards, R., Friend, S. H., Laurent-Puig, P., Medema, J. P., Sadanandam, A., Wessels, L., Delorenzi, M., Kopetz, S., Vermeulen, L. & Tejpar, S., Nov 1 2015, In : Nature medicine. 21, 11, p. 1350-1356 7 p.

Research output: Contribution to journalArticle

1338 Scopus citations

The distribution of nuclear DNA from human brain-tumor cells. Flow cytometric studies

Hoshino, T., Nomura, K., Wilson, C. B., Knebel, K. D. & Gray, J. W., Jan 1 1978, In : Unknown Journal. 49, 1, p. 13-21 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment

Turpin, J., Ling, C., Crosby, E. J., Hartman, Z. C., Simond, A. M., Chodosh, L. A., Rennhack, J. P., Andrechek, E. R., Ozcelik, J., Hallett, M., Mills, G. B., Cardiff, R. D., Gray, J. W., Griffith, O. L. & Muller, W. J., Nov 24 2016, In : Oncogene. 35, 47, p. 6053-6064 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas

Sun, Y., Wong, N., Guan, Y., Salamanca, C. M., Jung, C. C., Lee, J. M., Gray, J. W. & Auersperg, N., Oct 15 2008, In : International Journal of Cancer. 123, 8, p. 1761-1769 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer

Hu, Z., Huang, G., Sadanandam, A., Gu, S., Lenburg, M. E., Pai, M., Bayani, N., Blakely, E. A., Gray, J. W. & Mao, J. H., Mar 8 2010, In : Breast Cancer Research. 12, 2, R18.

Research output: Contribution to journalArticle

75 Scopus citations

The genetics and genomics of cancer

Balmain, A., Gray, J. & Ponder, B., Mar 2003, In : Nature genetics. 33, 3S, p. 238-244 7 p.

Research output: Contribution to journalReview article

437 Scopus citations

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., Kuleshov, M. V., Ma'ayan, A., Stathias, V., Terryn, R., Cooper, D., Forlin, M., Koleti, A., Vidovic, D., Chung, C., Schürer, S. C. & 87 others, Vasiliauskas, J., Pilarczyk, M., Shamsaei, B., Fazel, M., Ren, Y., Niu, W., Clark, N. A., White, S., Mahi, N., Zhang, L., Kouril, M., Reichard, J. F., Sivaganesan, S., Medvedovic, M., Meller, J., Koch, R. J., Birtwistle, M. R., Iyengar, R., Sobie, E. A., Azeloglu, E. U., Kaye, J., Osterloh, J., Haston, K., Kalra, J., Finkbiener, S., Li, J., Milani, P., Adam, M., Escalante-Chong, R., Sachs, K., Lenail, A., Ramamoorthy, D., Fraenkel, E., Daigle, G., Hussain, U., Coye, A., Rothstein, J., Sareen, D., Ornelas, L., Banuelos, M., Mandefro, B., Ho, R., Svendsen, C. N., Lim, R. G., Stocksdale, J., Casale, M. S., Thompson, T. G., Wu, J., Thompson, L. M., Dardov, V., Venkatraman, V., Matlock, A., Van Eyk, J. E., Jaffe, J. D., Papanastasiou, M., Subramanian, A., Golub, T. R., Erickson, S. D., Fallahi-Sichani, M., Hafner, M., Gray, N. S., Lin, J. R., Mills, C. E., Muhlich, J. L., Niepel, M., Shamu, C. E., Williams, E. H., Wrobel, D., Sorger, P. K., Heiser, L. M., Gray, J. W., Korkola, J. E., Mills, G. B., LaBarge, M., Feiler, H. S., Dane, M. A., Bucher, E., Nederlof, M., Sudar, D., Gross, S., Kilburn, D. F., Smith, R., Devlin, K., Margolis, R., Derr, L., Lee, A. & Pillai, A., Jan 24 2018, In : Cell Systems. 6, 1, p. 13-24 12 p.

Research output: Contribution to journalReview article

83 Scopus citations

The LLNL high‐speed sorter: Design features, operational characteristics, and biological utility

Peters, D., Branscomb, E., Dean, P., Merrill, T., Pinkel, D., Van Dilla, M. & Gray, J. W., Jul 1985, In : Cytometry. 6, 4, p. 290-301 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

Gupta, P. B., Kuperwasser, C., Brunet, J. P., Ramaswamy, S., Kuo, W. L., Gray, J. W., Naber, S. P. & Weinberg, R. A., Oct 1 2005, In : Nature genetics. 37, 10, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

326 Scopus citations

The Molecular Basis of Cancer: Fourth Edition

Mendelsohn, J., Gray, J. W., Howley, P. M., Israel, M. A. & Thompson, C. B., Mar 1 2014, Elsevier Inc. 863 p.

Research output: Book/ReportBook

The Molecular Basis of Cancer

Mendelsohn, J., Howley, P. M., Israel, M. A., Gray, J. & Thompson, C. B., 2008, Elsevier Inc.

Research output: Book/ReportBook

28 Scopus citations

The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression

Kenny, P. A., Lee, G. Y., Myers, C. A., Neve, R. M., Semeiks, J. R., Spellman, P. T., Lorenz, K., Lee, E. H., Barcellos-Hoff, M. H., Petersen, O. W., Gray, J. W. & Bissell, M. J., Jun 2007, In : Molecular Oncology. 1, 1, p. 84-96 13 p.

Research output: Contribution to journalArticle

621 Scopus citations

The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

Cheng, K. W., Lahad, J. P., Kuo, W. L., Lapuk, A., Yamada, K., Auersperg, N., Liu, J., Smith-McCune, K., Lu, K. H., Fishman, D., Gray, J. W. & Mills, G. B., Nov 1 2004, In : Nature medicine. 10, 11, p. 1251-1256 6 p.

Research output: Contribution to journalArticle

379 Scopus citations

Therapeutic Clues from an Integrated Omic Assessment of East Asian Triple Negative Breast Cancers

Heiser, L. M., Mills, G. B. & Gray, J. W., Mar 18 2019, In : Cancer Cell. 35, 3, p. 341-343 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Therapeutic siRNA for drug-resistant HER2-positive breast cancer

Gu, S., Hu, Z., Ngamcherdtrakul, W., Castro, D. J., Morry, J., Reda, M. M., Gray, J. W. & Yantasee, W., Mar 22 2016, In : Oncotarget. 7, 12, p. 14727-14741 15 p.

Research output: Contribution to journalArticle

15 Scopus citations
1 Scopus citations

The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy

Mills, G. B., Lu, Y., Fang, X., Wang, H., Eder, A., Mao, M., Swaby, R., Cheng, K. W., Stokoe, D., Siminovitch, K., Jaffe, R. & Gray, J., Jan 1 2001, In : Seminars in Oncology. 28, 5 SUPPL. 16, p. 125-141 17 p.

Research output: Contribution to journalArticle

112 Scopus citations

The Role of p53 in Suppression of KSHV Cyclin-induced Lymphomagenesis

Verschuren, E. W., Hodgson, J. G., Gray, J. W., Kogan, S., Jones, N. & Evan, G. I., Jan 15 2004, In : Cancer Research. 64, 2, p. 581-589 9 p.

Research output: Contribution to journalArticle

68 Scopus citations

The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model.

Donehower, L. A., Godley, L. A., Aldaz, C. M., Pyle, R., Shi, Y. P., Pinkel, D., Gray, J., Bradley, A., Medina, D. & Varmus, H. E., 1996, In : Progress in clinical and biological research. 395, p. 1-11 11 p.

Research output: Contribution to journalReview article

21 Scopus citations