• 67302 Citations
  • 113 h-Index
1971 …2020

Research output per year

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Research Output

1994

Identification of Frequent Novel Genetic Alterations in Small Cell Lung Carcinoma

Levin, N. A., Brzoska, P., Gupta, N., Gray, J. W. & Christman, M. F., Oct 1 1994, In : Cancer Research. 54, 19, p. 5086-5091 6 p.

Research output: Contribution to journalArticle

80 Scopus citations

Increased Copy Number at 20ql3 in Breast Cancer: Defining the Critical Region and Exclusion of Candidate Genes1

Tanner, M. M., Tirkkonen, M., Kallioniemi, A., Collins, C., Stokke, T., Karhu, R., Kowbel, D., Shadravan, F., Hintz, M., Kuo, W. L., Waldman, F. M., Isola, J. J., Gray, J. W. & Kallioniemi, O. P., Aug 1994, In : Cancer Research. 54, 16, p. 4257-4260 4 p.

Research output: Contribution to journalArticle

166 Scopus citations

Interphase cytogenetics of melanocytic neoplasms: numerical aberrations of chromosomes can be detected in interphase nuclei using centromeric DNA probes

Matsuta, M., Matsuta, M., Kon, S., Thompson, C., LeBoit, P. E., Weier, H. U. & Gray, J. W., Feb 1994, In : Journal of cutaneous pathology. 21, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Intracellular dynamics of c‐myc mRNA traffic in single cells in situ

Pallavicini, M. G., George, T., Deteresa, P. S., Amendola, R. & Gray, J. W., Feb 1994, In : Journal of Cellular Physiology. 158, 2, p. 223-230 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Molecular cytogenetics of human breast cancer

Gray, J. W., Collins, C., Henderson, I. C., Isola, J., Kallioniemi, A., Kallioniemi, O. P., Nakamura, H., Pinkel, D., Stokke, T., Tanner, M. & Waldman, F., 1994, In : Cold Spring Harbor symposia on quantitative biology. 59, p. 645-652 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors

Kallioniemi, OP. P., Kallioniemi, A., Piper, J., Isola, J., Waldman, F. M., Gray, J. W. & Pinkel, D., Aug 1994, In : Genes, Chromosomes and Cancer. 10, 4, p. 231-243 13 p.

Research output: Contribution to journalReview article

933 Scopus citations

Physical mapping of chromosome 17 cosmids by fluorescence in situ hybridization and digital image analysis

Kallioniemi, O. P., Kallioniemi, A., Mascio, L., Sudar, D., Pinkel, D., Deaven, L. & Gray, J., Mar 1 1994, In : Genomics. 20, 1, p. 125-128 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Statement on Use of DNA Testing for Presymptomatic Identification of Cancer Risk

Collins, F. S., Benjamin, L. J., Botstein, D., Cox, J. R., Davidson, N., Gray, J. W., Housman, D. E., Holtzman, N., Jamison, K. R., Rothstein, R., Smith, D. C., Smith, L. M., Spence, M. A. & Tilghman, S. M., Mar 9 1994, In : JAMA: The Journal of the American Medical Association. 271, 10, 1 p.

Research output: Contribution to journalArticle

130 Scopus citations

Thick-section fluorescence in situ hybridization on formalin-fixed, paraffin-embedded archival tissue provides a histogenetic profile

Thompson, C. T., LeBoit, P. E., Nederlof, P. M. & Gray, J. W., Feb 1 1994, In : American Journal of Pathology. 144, 2, p. 237-243 7 p.

Research output: Contribution to journalArticle

61 Scopus citations
1993

Application of confocal laser scanning microscope on fluorescence in situ hybridization (FISH)

Matsuta, M., Matsuta, M., Sasaki, K., Hariu, H., Nishiya, I., Katou, M., Kallioniemi, A., Weier, H. U. & Gray, J. W., Jan 1 1993, In : Acta Histochemica et Cytochemica. 26, 5, p. 415-421 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Application of x rays to the analysis of DNA packaging in mammalian sperm

Balhorn, R., Corzett, M., Allen, M. J., Lee, C., Barbee, T. W., Koch, J. A., MacGowan, B. J., Matthews, D. L., Mrowka, S. J., Trebes, J. E., McNulty, I., Da Silva, L. B., Gray, J. W., Anderson, E. H., Kern, D. & Attwood, D. T., Jan 1 1993, Proceedings of SPIE - The International Society for Optical Engineering. Publ by Int Soc for Optical Engineering, p. 374-385 12 p. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 1741).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Chromosomal reassignment: Yacs containing both yes1 and thymidylate synthase map to the short arm of chromosome 18

Silverman, G. A., Kuo, W. L., Taillon-Miller, P. & Gray, J. W., Feb 1993, In : Genomics. 15, 2, p. 442-445 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cloning and Characterization of EagI YACs from Human Chromosome 21

Gingrich, J. C., Lowry, S. R., Kuo, W. L., Gray, J., Smith, C. L. & Cantori, C. R., Jan 1993, In : Genomics. 15, 1, p. 228-230 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Comparative genomic hybridization: A rapid new method for detecting and mapping DNA amplification in tumors

Kallioniemi, O. P., Kallioniemi, A., Sudar, D., Rutovitz, D., Gray, J. W., Waldman, F. & Pinkel, D., Dec 1 1993, In : Seminars in Cancer Biology. 4, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

202 Scopus citations

Cytogenetic profiling using fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH)

Thompson, C. T. & Gray, J. W., 1993, In : Journal of cellular biochemistry. 53, S17G, p. 139-143 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Derivative domain fitting: A new method for resolving a mixture of normal distributions in the presence of a contaminating background

Moore, D. H. & Gray, J. W., 1993, In : Cytometry. 14, 5, p. 510-518 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
18 Scopus citations

Imaging microscopy with x-ray lasers at LLNL

Da Silva, L. B., Trebes, J. E., Mrowka, S. J., MacGowan, B. J., Koch, J. A., Matthews, D. L., Barbee, T. W., Balhorn, R., Gray, J. W., Anderson, E. H., Kern, D. & Attwood, D. T., Jan 1 1993, Proceedings of SPIE - The International Society for Optical Engineering. Publ by Int Soc for Optical Engineering, p. 154-159 6 p. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 1741).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Libraries for each human chromosome, constructed from sorter-enriched chromosomes by using linker-adaptor PCR

Vooijs, M., Yu, L. C., Tkachuk, D., Pinkel, D., Johnson, D. & Gray, J. W., Jan 1 1993, In : American Journal of Human Genetics. 52, 3, p. 586-597 12 p.

Research output: Contribution to journalArticle

59 Scopus citations

Molecular Cytogenetic Analysis of Human Tumors

GRAY, JOE. W., Mar 1993, In : Annals of the New York Academy of Sciences. 677, 1, p. 194-198 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Molecular cytogenetics: Solid tumors and leukemia

Gray, J. W. & Pallavicini, M. G., Dec 1 1993, In : Blood Cells. 19, 3, p. 677-683 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
1992
43 Scopus citations

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

Kallioniemi, A., Kallioniemi, O. P., Sudar, D., Rutovitz, D., Gray, J. W., Waldman, F. & Pinkel, D., Jan 1 1992, In : Science. 258, 5083, p. 818-821 4 p.

Research output: Contribution to journalArticle

2750 Scopus citations

Construction and characterization of a yeast artificial chromosome library containing 1.5 equivalents of human chromosome 21

Potier, M. C., Kuo, W. L., Dutriaux, A., Gray, J. & Goedert, M., Oct 1992, In : Genomics. 14, 2, p. 481-483 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

Deletion of Chromosome 17p Loci in Breast Cancer Cells Detected by Fluorescence in Situ Hybridization

Matsumura, K., Kallioniemi, A., Kallioniemi, O., Chen, L., Smith, H. S., Pinkel, D., Gray, J. & Waldman, F. M., Jun 1992, In : Cancer Research. 52, 12, p. 3474-3477 4 p.

Research output: Contribution to journalArticle

107 Scopus citations

Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization

Kallioniemi, A., Kallioniemi, O. P., Waidman, F. M., Chen, L. C., Yu, L. C., Fung, Y. K. T., Smith, H. S., Pinkel, D. & Gray, J. W., Jan 1 1992, In : Cytogenetic and Genome Research. 60, 3-4, p. 190-193 4 p.

Research output: Contribution to journalArticle

45 Scopus citations

Differential staining of human and murine chromatin in situ by hybridization with species-specific satellite DNA probes

Weier, H. U. G., Zitzelsberger, H. F. & Gray, J. W., Feb 14 1992, In : Biochemical and Biophysical Research Communications. 182, 3, p. 1313-1319 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization

Kallioniemi, O. P., Kallioniemi, A., Kurisu, W., Thor, A., Chen, L. C., Smith, H. S., Waldman, F. M., Pinkel, D. & Gray, J. W., Jun 22 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 12, p. 5321-5325 5 p.

Research output: Contribution to journalArticle

Open Access
443 Scopus citations

Factors that Determine the in vivo Dose-Response Relationship for Stable Chromosome Aberrations in A-Bomb Survivors

Awa, A. A., Nakano, M., Ohtaki, K., Kodama, Y., Lucas, J. & Gray, J., Jan 1 1992, In : Journal of radiation research. 33, p. 206-214 9 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Molecular cytogenetics: Diagnosis and prognostic assessment

Gray, J. W., Kallioniemi, A., Kallioniemi, O., Pallavicini, M., Waldman, F. & Pinkel, D., Dec 1992, In : Current Opinion in Biotechnology. 3, 6, p. 623-631 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Molecular cytogenetics in human cancer diagnosis

Gray, J. W. & Pinkel, D., Mar 15 1992, In : Cancer. 69, 6 S, p. 1536-1542 7 p.

Research output: Contribution to journalArticle

67 Scopus citations

Radiation-induced chromosome aberrations analysed by fluorescence in situ hybridization with a triple combination of composite whole chromosome-specific DNA probes

Schmid, E., Zitzelsberger, H., Braselmann, H., Gray, J. W. & Bauchinger, M., Jan 1 1992, In : International Journal of Radiation Biology. 62, 6, p. 673-678 6 p.

Research output: Contribution to journalArticle

131 Scopus citations

Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation

Lucas, J. N., Awa, A., Straume, T., Poggensee, M., Kodama, Y., Nakano, M., Ohtaki, K., Weier, H. U., Pinkel, D., Gray, J. & Littlefield, G., Jan 1 1992, In : International Journal of Radiation Biology. 62, 1, p. 53-63 11 p.

Research output: Contribution to journalArticle

426 Scopus citations

Structural Chromosome Analysis by Whole Chromosome Painting for Assessment of Radiation-Induced Genetic Damage

Gray, J. W., Pinkel, D., Lucas, J. N. & Awa, A., Jan 1 1992, In : Journal of radiation research. 33, p. 80-86 7 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

X-ray laser microscopy of rat sperm nuclei

Da Silva, L. B., Trebes, J. E., Balhorn, R., Mrowka, S., Anderson, E., Attwood, D. T., Barbee, T. W., Brase, J., Corzett, M., Gray, J., Koch, J. A., Lee, C., Kern, D., London, R. A., MacGowan, B. J., Matthews, D. L. & Stone, G., Jan 1 1992, In : Science. 258, 5080, p. 269-271 3 p.

Research output: Contribution to journalArticle

128 Scopus citations
1991

Applications of fluorescence in situ hybridization in biological dosimetry and detection of disease-specific chromosome aberrations.

Gray, J. W., Lucas, J., Kallioniemi, O., Kallioniemi, A., Kuo, W. L., Straume, T., Tkachuk, D., Tenjin, T., Weier, H. U. & Pinkel, D., 1991, In : Progress in clinical and biological research. 372, p. 399-411 13 p.

Research output: Contribution to journalReview article

19 Scopus citations

Characterization of somatic cell hybrids by bivariate flow karyotyping and fluorescence in situ hybridization

Trask, B. J., van den Engh, G., Christensen, M., Massa, H. F., Gray, J. W. & Van Dilla, M., Mar 1 1991, In : Somatic Cell and Molecular Genetics. 17, 2, p. 117-136 20 p.

Research output: Contribution to journalArticle

38 Scopus citations

Clinical applications of fluorescence in situ hybridization

Tkachuk, D. C., Pinkel, D., Kuo, W. L., Weier, H. U. & Gray, J. W., Apr 1991, In : Genetic Analysis: Biomolecular Engineering. 8, 2, p. 67-74 8 p.

Research output: Contribution to journalArticle

81 Scopus citations

Construction and characterization of plasmid libraries enriched in sequences from single human chromosomes

Collins, C., Kuo, W. L., Segraves, R., Fuscoe, J., Pinkel, D. & Gray, J. W., Dec 1991, In : Genomics. 11, 4, p. 997-1006 10 p.

Research output: Contribution to journalArticle

213 Scopus citations

Detection of aneuploidy involving chromosomes 13, 18, or 21, by fluorescence in situ hybridization (FISH) to interphase and metaphase amniocytes

Kuo, W. L., Tenijn, H., Segraves, R., Pinkel, D., Golbus, M. S. & Gray, J., Aug 29 1991, In : American Journal of Human Genetics. 49, 1, p. 112-119 8 p.

Research output: Contribution to journalArticle

113 Scopus citations

Dicentric chromosome frequency analysis using slit‐scan flow cytometry

Lucas, J. N., Mullikin, J. C. & Gray, J. W., 1991, In : Cytometry. 12, 4, p. 316-322 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Labeling of the centromeric region on human chromosome 8 by in situ hybridization

Weier, H. U. G., Gray, J. W. & Kleine, H. D., Aug 1 1991, In : Human genetics. 87, 4, p. 489-494 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Non-isotopical labeling of murine heterochromatin in situ by hybridization with in vitro-synthesized biotinylated gamma (major) satellite DNA

Weier, H. U., Zitzelsberger, H. F. & Gray, J. W., Jun 28 1991, In : BioTechniques. 10, 4, p. 498-502+504-505

Research output: Contribution to journalArticle

39 Scopus citations

Observations regarding DNA replication sites in human cells in vivo following infusions of iododeoxyuridine and bromodeoxyuridine

Raza, A., Miller, M. A., Mazewski, C., Sheikh, Y., Lampkin, B., Sawaya, R., Crone, K., Berger, T., Reising, J., Gray, J., Khan, S. & Preisler, H., Mar 1991, In : Cell Proliferation. 24, 2, p. 113-126 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Two-color hybridization with high complexity chromosome-specific probes and a degenerate alpha satellite probe DNA allows unambiguous discrimination between symmetrical and asymmetrical translocations

Weier, H. U. G., Lucas, J. N., Poggensee, M., Segraves, R., Pinkel, D. & Gray, J. W., Jul 1 1991, In : Chromosoma. 100, 6, p. 371-376 6 p.

Research output: Contribution to journalArticle

74 Scopus citations
1990

Analytical approaches to detection and characterization of disease-linked chromosome aberrations

Gray, J. W., Kuo, W. L., Liang, J., Pinkel, D., Van den Engh Trask, G. B., Tkachuk, D., Waldman, F. & Westbrook, C., Jan 1 1990, In : Bone marrow transplantation. 6, SUPPL. 1, p. 14-19 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Automated detection of chromosome aberration using color information

Chen, C. H., Wang, Y., Mitra, S. K. & Gray, J., Mar 1 1990, In : Proceedings of SPIE - The International Society for Optical Engineering. 1192, p. 339-343 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine

Asai, A., Shibui, S., Barker, M., Vanderlaan, M., Gray, J. W. & Hoshino, T., Jan 1 1990, In : Journal of neurosurgery. 73, 2, p. 254-258 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Chapter 21 Using Monoclonal Antibodies in Bromodeoxyuridine—DNA Analysis

Dolbeare, F., Kuo, W. L., Beisker, W., Vanderlaan, M. & Gray, J. W., Jan 1 1990, In : Methods in cell biology. 33, C, p. 207-216 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Characterization and organization of DNA sequences adjacent to the human telomere associated repeat (TTAGGG)n

Weber, B., Collins, C., Robbins, C., Magenis, R. E., Delaney, A. D., Gray, J. W. & Hayden, M. R., Jun 11 1990, In : Nucleic acids research. 18, 11, p. 3353-3361 9 p.

Research output: Contribution to journalArticle

44 Scopus citations