• 67302 Citations
  • 113 h-Index
1971 …2020

Research output per year

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Research Output

2015

Genome-wide perturbations by miRNAs map onto functional cellular pathways, identifying regulators of chromatin modifiers

Moss, T. J., Luo, Z., Seviour, E. G., Sehgal, V., Lu, Y., Hill, S. M., Rupaimoole, R., Lee, J. S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Sood, A. K., Azencott, R., Gray, J., Mukherjee, S., Mills, G. & Ram, P. T., Sep 28 2015, In : npj Systems Biology and Applications. 1, 15001.

Research output: Contribution to journalArticle

2 Scopus citations

Heterogeneity in cancer dynamics: A convex formulation to dissect dynamic trajectories and infer LTV models of networked systems

Dobbe, R., Chang, Y. H., Korkola, J., Gray, J. & Tomlin, C., Jul 28 2015, ACC 2015 - 2015 American Control Conference. Institute of Electrical and Electronics Engineers Inc., p. 4398-4403 6 p. 7172021. (Proceedings of the American Control Conference; vol. 2015-July).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Large-scale drug screens support precision medicine

Gray, J. W. & Mills, G. B., Nov 2015, In : Cancer discovery. 5, 11, p. 1130-1132 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination

Sanborn, J. Z., Chung, J., Purdom, E., Wang, N. J., Kakavand, H., Wilmott, J. S., Butler, T., Thompson, J. F., Mann, G. J., Haydu, L. E., Saw, R. P. M., Busam, K. J., Lo, R. S., Collisson, E. A., Hur, J. S., Spellman, P. T., Cleaver, J. E., Gray, J. W., Huh, N., Murali, R. & 3 others, Scolyer, R. A., Bastian, B. C. & Cho, R. J., Sep 1 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 35, p. 10995-11000 6 p.

Research output: Contribution to journalArticle

66 Scopus citations

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway

Nan, X., Tamgüney, T. M., Collisson, E. A., Lin, L. J., Pitt, C., Galeas, J., Lewis, S., Gray, J. W., McCormick, F. & Chu, S., Jun 30 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 26, p. 7996-8001 6 p.

Research output: Contribution to journalArticle

120 Scopus citations

The consensus molecular subtypes of colorectal cancer

Guinney, J., Dienstmann, R., Wang, X., De Reyniès, A., Schlicker, A., Soneson, C., Marisa, L., Roepman, P., Nyamundanda, G., Angelino, P., Bot, B. M., Morris, J. S., Simon, I. M., Gerster, S., Fessler, E., De Sousa .E Melo, F., Missiaglia, E., Ramay, H., Barras, D., Homicsko, K. & 20 others, Maru, D., Manyam, G. C., Broom, B., Boige, V., Perez-Villamil, B., Laderas, T., Salazar, R., Gray, J. W., Hanahan, D., Tabernero, J., Bernards, R., Friend, S. H., Laurent-Puig, P., Medema, J. P., Sadanandam, A., Wessels, L., Delorenzi, M., Kopetz, S., Vermeulen, L. & Tejpar, S., Nov 1 2015, In : Nature medicine. 21, 11, p. 1350-1356 7 p.

Research output: Contribution to journalArticle

1287 Scopus citations

Upregulation of ER signaling as an adaptive mechanism of cell survival in HER2-positive breast tumors treated with Anti-HER2 therapy

Giuliano, M., Hu, H., Wang, Y. C., Fu, X., Nardone, A., Herrera, S., Mao, S., Contreras, A., Gutierrez, C., Wang, T., Hilsenbeck, S. G., Angelis, C. D., Wang, N. J., Heiser, L. M., Gray, J. W., Lopez-Tarruella, S., Pavlick, A. C., Trivedi, M. V., Chamness, G. C., Chang, J. C. & 3 others, Osborne, C. K., Rimawi, M. F. & Schiff, R., Sep 1 2015, In : Clinical Cancer Research. 21, 17, p. 3995-4003 9 p.

Research output: Contribution to journalArticle

42 Scopus citations
2016

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

Bruna, A., Rueda, O. M., Greenwood, W., Batra, A. S., Callari, M., Batra, R. N., Pogrebniak, K., Sandoval, J., Cassidy, J. W., Tufegdzic-Vidakovic, A., Sammut, S. J., Jones, L., Provenzano, E., Baird, R., Eirew, P., Hadfield, J., Eldridge, M., McLaren-Douglas, A., Barthorpe, A., Lightfoot, H. & 10 others, O'Connor, M. J., Gray, J., Cortes, J., Baselga, J., Marangoni, E., Welm, A. L., Aparicio, S., Serra, V., Garnett, M. J. & Caldas, C., Sep 22 2016, In : Cell. 167, 1, p. 260-274.e22

Research output: Contribution to journalArticle

147 Scopus citations

ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin

Fleyshman, D., Cheney, P., Ströse, A., Mudambi, S., Safina, A., Commane, M., Purmal, A., Morgan, K., Wang, N. J., Gray, J., Spellman, P., Issaeva, N. & Gurova, K., Feb 1 2016, In : Cell Cycle. 15, 3, p. 455-470 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast

Campbell, M. J., Baehner, F., O’Meara, T., Ojukwu, E., Han, B., Mukhtar, R., Tandon, V., Endicott, M., Zhu, Z., Wong, J., Krings, G., Au, A., Gray, J. & Esserman, L., Oct 26 2016, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-12 12 p.

Research output: Contribution to journalArticle

39 Scopus citations

Current development of targeted oligonucleotide-based cancer therapies: Perspective on HER2-positive breast cancer treatment

Ngamcherdtrakul, W., Castro, D. J., Gu, S., Morry, J., Reda, M., Gray, J. & Yantasee, W., Apr 1 2016, In : Cancer Treatment Reviews. 45, p. 19-29 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Erratum: Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer (Oncogene (2016) 35 (691-701) DOI:10.1038/onc.2014.469)

Seviour, E. G., Sehgal, V., Lu, Y., Luo, Z., Moss, T., Zhang, F., Hill, S. M., Liu, W., Maiti, S. N., Cooper, L., Azencot, R., Lopez-Berestein, G., Rodriguez-Aguayo, C., Roopaimoole, R., Pecot, C. V., Sood, A. K., Mukherjee, S., Gray, J. W., Mills, G. B. & Ram, P. T., Feb 11 2016, In : Oncogene. 35, 6, p. 801 1 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

Fu, X., Jeselsohn, R., Pereira, R., Hollingsworth, E. F., Creighton, C. J., Li, F., Shea, M., Nardone, A., De Angelis, C., Heiser, L. M., Anur, P., Wang, N., Grasso, C. S., Spellman, P. T., Griffith, O. L., Tsimelzon, A., Gutierrez, C., Huang, S., Edwards, D. P., Trivedi, M. V. & 7 others, Rimawi, M. F., Lopez-Terrada, D., Hilsenbeck, S. G., Gray, J. W., Brown, M., Osborne, C. K. & Schiff, R., Oct 25 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 43, p. E6600-E6609

Research output: Contribution to journalArticle

46 Scopus citations

Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death

Guest, S. T., Kratche, Z. R., Irish, J. C., Wilson, R. C., Haddad, R., Gray, J. W., Garrett-Mayer, E. & Ethier, S. P., Jan 1 2016, In : Oncotarget. 7, 24, p. 36138-36153 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer

Seviour, E. G., Sehgal, V., Lu, Y., Luo, Z., Moss, T., Zhang, F., Hill, S. M., Liu, W., Maiti, S. N., Cooper, L., Azencot, R., Lopez-Berestein, G., Rodriguez-Aguayo, C., Roopaimoole, R., Pecot, C., Sood, A. K., Mukherjee, S., Gray, J., Mills, G. & Ram, P. T., Feb 11 2016, In : Oncogene. 35, 6, p. 691-701 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

Hu, Z., Mao, J. H., Curtis, C., Huang, G., Gu, S., Heiser, L., Lenburg, M. E., Korkola, J. E., Bayani, N., Samarajiwa, S., Seoane, J. A., Dane, M., Esch, A., Feiler, H. S., Wang, N., Hardwicke, M. A., Laquerre, S., Jackson, J., Wood, K., Weber, B. & 5 others, Spellman, P. T., Aparicio, S., Wooster, R., Caldas, C. & Gray, J. W., Jul 1 2016, In : Breast Cancer Research. 18, 1, 70.

Research output: Contribution to journalArticle

6 Scopus citations

IL-10 and integrin signaling pathways are associated with head and neck cancer progression

Bornstein, S., Schmidt, M., Choonoo, G., Levin, T., Gray, J., Thomas, C., Wong, M. & McWeeney, S., Jan 8 2016, In : BMC Genomics. 17, 1, 38.

Research output: Contribution to journalArticle

25 Scopus citations

Inferring causal molecular networks: Empirical assessment through a community-based effort

Hill, S. M., Heiser, L. M., Cokelaer, T., Linger, M., Nesser, N. K., Carlin, D. E., Zhang, Y., Sokolov, A., Paull, E. O., Wong, C. K., Graim, K., Bivol, A., Wang, H., Zhu, F., Afsari, B., Danilova, L. V., Favorov, A. V., Lee, W. S., Taylor, D., Hu, C. W. & 115 others, Long, B. L., Noren, D. P., Bisberg, A. J., Mills, G. B., Gray, J. W., Kellen, M., Norman, T., Friend, S., Qutub, A. A., Fertig, E. J., Guan, Y., Song, M., Stuart, J. M., Spellman, P. T., Koeppl, H., Stolovitzky, G., Saez-Rodriguez, J., Mukherjee, S., Al-Ouran, R., Anton, B., Arodz, T., Sichani, O. A., Bagheri, N., Berlow, N., Bohler, A., Bonet, J., Bonneau, R., Budak, G., Bunescu, R., Caglar, M., Cai, B., Cai, C., Carlon, A., Chen, L., Ciaccio, M. F., Cooper, G., Coort, S., Creighton, C. J., Daneshmand, S. M. H., De La Fuente, A., Di Camillo, B., Dutta-Moscato, J., Emmett, K., Evelo, C., Fassia, M. K. H., Finotello, F., Finkle, J. D., Gao, X., Garcia-Garcia, J., Ghosh, S., Giaretta, A., Großeholz, R., Guinney, J., Hafemeister, C., Hahn, O., Haider, S., Hase, T., Hodgson, J., Hoff, B., Hsu, C. H., Hu, Y., Huang, X., Jalili, M., Jiang, X., Kacprowski, T., Kaderali, L., Kang, M., Kannan, V., Kikuchi, K., Kim, D. C., Kitano, H., Knapp, B., Komatsoulis, G., Krämer, A., Kursa, M. B., Kutmon, M., Li, Y., Liang, X., Liu, Z., Liu, Y., Lu, S., Lu, X., Manfrini, M., Matos, M. R. A., Meerzaman, D., Min, W., Müller, C. L., Neapolitan, R. E., Oliva, B., Opiyo, S. O., Pal, R., Palinkas, A., Planas-Iglesias, J., Poglayen, D., Sambo, F., Sanavia, T., Sharifi-Zarchi, A., Slawek, J., Streck, A., Strunz, S., Tegnér, J., Thobe, K., Toffolo, G. M., Trifoglio, E., Unger, M., Wan, Q., Welch, L., Wu, J. J., Xue, A. Y., Yamanaka, R., Yan, C., Zairis, S., Zengerling, M., Zenil, H. & Zi, Z., Mar 30 2016, In : Nature Methods. 13, 4, p. 310-322 13 p.

Research output: Contribution to journalArticle

102 Scopus citations

Multiplexed imaging reveals heterogeneity of PI3K/MAPK network signaling in breast lesions of known PIK3CA genotype

Jacob, T., Gray, J., Troxell, M. & Vu, T. T., Oct 1 2016, In : Breast Cancer Research and Treatment. 159, 3, p. 575-583 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

PI3 Kinase Pathway Mutations in Human Cancers

Gray, J., Dec 1 2016, In : JAMA oncology. 2, 12, p. 1543-1544 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Quantitative analysis of histological tissue image based on cytological profiles and spatial statistics

Chang, Y. H., Thibault, G., Azimi, V., Johnson, B., Jorgens, D., Link, J., Margolin, A. & Gray, J., Oct 13 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., Vol. 2016-October. p. 1175-1178 4 p. 7590914

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Reconstruction of Gene Regulatory Networks Based on Repairing Sparse Low-Rank Matrices

Chang, Y. H., Dobbe, R., Bhushan, P., Gray, J. & Tomlin, C. J., Jul 1 2016, In : IEEE/ACM Transactions on Computational Biology and Bioinformatics. 13, 4, p. 767-777 11 p., 7182286.

Research output: Contribution to journalArticle

Retrieving common dynamics of gene regulatory networks under various perturbations

Chang, Y. H., Dobbe, R., Bhushan, P., Gray, J. & Tomlin, C. J., Feb 8 2016, Proceedings of the IEEE Conference on Decision and Control. Institute of Electrical and Electronics Engineers Inc., Vol. 2016-February. p. 2531-2536 6 p. 7402597

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment

Turpin, J., Ling, C., Crosby, E. J., Hartman, Z. C., Simond, A. M., Chodosh, L. A., Rennhack, J. P., Andrechek, E. R., Ozcelik, J., Hallett, M., Mills, G. B., Cardiff, R. D., Gray, J. W., Griffith, O. L. & Muller, W. J., Nov 24 2016, In : Oncogene. 35, 47, p. 6053-6064 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Therapeutic siRNA for drug-resistant HER2-positive breast cancer

Gu, S., Hu, Z., Ngamcherdtrakul, W., Castro, D. J., Morry, J., Reda, M. M., Gray, J. W. & Yantasee, W., Mar 22 2016, In : Oncotarget. 7, 12, p. 14727-14741 15 p.

Research output: Contribution to journalArticle

15 Scopus citations

Tumor-derived cell lines as molecular models of cancer pharmacogenomics

Goodspeed, A., Heiser, L., Gray, J. & Costello, J. C., Jan 1 2016, In : Molecular Cancer Research. 14, 1, p. 3-13 11 p.

Research output: Contribution to journalArticle

82 Scopus citations
2017

Activity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypes

Rahman, M., MacNeil, S. M., Jenkins, D. F., Shrestha, G., Wyatt, S. R., McQuerry, J. A., Piccolo, S. R., Heiser, L. M., Gray, J. W., Johnson, W. E. & Bild, A. H., Apr 26 2017, In : Genome Medicine. 9, 1, 40.

Research output: Contribution to journalArticle

5 Scopus citations

A fully integrated, three-dimensional fluorescence to electron microscopy correlative workflow

Lopez, C., Bouchet-Marquis, C., Arthur, C. P., McQuiston, J., Heiss, G., Thibault, G., Pullan, L., Kwon, S. & Gray, J., 2017, (Accepted/In press) In : Methods in Cell Biology.

Research output: Contribution to journalArticle

8 Scopus citations

Bayesian network inference modeling identifies TRIB1 as a novel regulator of cell-cycle progression and survival in cancer cells

Gendelman, R., Xing, H., Mirzoeva, O. K., Sarde, P., Curtis, C., Feiler, H., McDonagh, P., Gray, J., Khalil, I. & Korn, W. M., 2017, In : Cancer Research. 77, 7, p. 1575-1585 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Breast cancer histopathology image analysis pipeline for tumor purity estimation

Azimi, V., Chang, Y. H., Thibault, G., Smith, J., Tsujikawa, T., Kukull, B., Jensen, B., Corless, C., Margolin, A. & Gray, J., Jun 15 2017, 2017 IEEE 14th International Symposium on Biomedical Imaging, ISBI 2017. IEEE Computer Society, p. 1137-1140 4 p. 7950717

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Circulating-tumor DNA as an early detection and diagnostic tool

Butler, T. M., Spellman, P. & Gray, J., Feb 1 2017, In : Current Opinion in Genetics and Development. 42, p. 14-21 8 p.

Research output: Contribution to journalReview article

28 Scopus citations

Combating subclonal evolution of resistant cancer phenotypes

Brady, S. W., McQuerry, J. A., Qiao, Y., Piccolo, S. R., Shrestha, G., Jenkins, D. F., Layer, R. M., Pedersen, B. S., Miller, R. H., Esch, A., Selitsky, S. R., Parker, J. S., Anderson, L. A., Dalley, B. K., Factor, R. E., Reddy, C. B., Boltax, J. P., Li, D. Y., Moos, P. J., Gray, J. W. & 8 others, Heiser, L. M., Buys, S. S., Cohen, A. L., Johnson, W. E., Quinlan, A. R., Marth, G., Werner, T. L. & Bild, A. H., Dec 1 2017, In : Nature communications. 8, 1, 1231.

Research output: Contribution to journalArticle

32 Scopus citations

Combinatorial Microenvironments Impose a Continuum of Cellular Responses to a Single Pathway-Targeted Anti-cancer Compound

Lin, C. H., Jokela, T., Gray, J. & LaBarge, M. A., Oct 10 2017, In : Cell Reports. 21, 2, p. 533-545 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

Hill, S. M., Nesser, N. K., Johnson-Camacho, K., Jeffress, M., Johnson, A., Boniface, C., Spencer, S. E. F., Lu, Y., Heiser, L. M., Lawrence, Y., Pande, N. T., Korkola, J. E., Gray, J. W., Mills, G. B., Mukherjee, S. & Spellman, P. T., Jan 25 2017, In : Cell Systems. 4, 1, p. 73-83.e10

Research output: Contribution to journalArticle

12 Scopus citations

Correction: Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer (PLoS ONE (2015) 10:7 (e0133219) DOI: 10.1371/journal.pone.0133219)

Korkola, J. E., Collisson, E. A., Heiser, L. M., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N. J., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Jakkula, L., Feiler, H., Lu, Y., Mills, G. B., Spellman, P. T. & 3 others, Tomlin, C., Mukherjee, S. & Gray, J. W., Oct 1 2017, In : PLoS One. 12, 10, e0186551.

Research output: Contribution to journalComment/debate

Deep learning based Nucleus Classification in pancreas histological images

Chang, Y. H., Thibault, G., Madin, O., Azimi, V., Meyers, C., Johnson, B., Link, J., Margolin, A. & Gray, J., Sep 13 2017, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., p. 672-675 4 p. 8036914

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Scopus citations

Epigenomic inactivation of RasGAPs activates RAS signaling in a subset of luminal B breast cancers

Sears, R. & Gray, J., Feb 1 2017, In : Cancer Discovery. 7, 2, p. 131-133 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

Erratum to: "Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer", [Breast Cancer Research, 19, (2017) (17)] DOI: 10.1186/s13058-017-0809-6

Hu, Z., Mao, J. H., Curtis, C., Huang, G., Gu, S., Heiser, L., Lenburg, M. E., Korkola, J. E., Bayani, N., Samarajiwa, S., Seoane, J. A., Dane, M. A., Esch, A., Feiler, H. S., Wang, N. J., Hardwicke, M. A., Laquerre, S., Jackson, J., Wood, K. W., Weber, B. & 5 others, Spellman, P. T., Aparicio, S., Wooster, R., Caldas, C. & Gray, J. W., Feb 9 2017, In : Breast Cancer Research. 19, 1, 17.

Research output: Contribution to journalComment/debate

HER2 reactivation through acquisition of the HER2 L755S mutation as a mechanism of acquired resistance to HER2-targeted therapy in HER2+ breast cancer

Xu, X., De Angelis, C., Burke, K. A., Nardone, A., Hu, H., Qin, L., Veeraraghavan, J., Sethunath, V., Heiser, L., Wang, N., Ng, C. K. Y., Chen, E. S., Renwick, A., Wang, T., Nanda, S., Shea, M., Mitchell, T., Rajendran, M., Waters, I., Zabransky, D. J. & 14 others, Scott, K. L., Gutierrez, C., Nagi, C., Geyer, F. C., Chamness, G. C., Park, B. H., Shaw, C. A., Hilsenbeck, S. G., Rimawi, M. F., Gray, J., Weigelt, B., Reis-Filho, J. S., Osborne, C. K. & Schiff, R., Sep 1 2017, In : Clinical Cancer Research. 23, 17, p. 5123-5134 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Integrative analysis on histopathological image for identifying cellular heterogeneity

Chang, Y. H., Thibault, G., Johnson, B., Margolin, A. & Gray, J., 2017, Medical Imaging 2017: Digital Pathology. SPIE, Vol. 10140. 101400T

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Multiplexed immunohistochemistry image analysis using sparse coding

Chang, Y. H., Tsujikawa, T., Margolin, A., Coussens, L. & Gray, J., Sep 13 2017, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., p. 4046-4049 4 p. 8037744

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Pathway-enriched gene signature associated with 53BP1 response to PARP inhibition in triple-negative breast cancer

Hassan, S., Esch, A., Liby, T., Gray, J. & Heiser, L., Dec 1 2017, In : Molecular Cancer Therapeutics. 16, 12, p. 2892-2901 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

Hafner, M., Heiser, L., Williams, E. H., Niepel, M., Wang, N. J., Korkola, J., Gray, J. & Sorger, P. K., Nov 7 2017, In : Scientific data. 4, 170166.

Research output: Contribution to journalArticle

9 Scopus citations

Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy

Zhang, Y., Huang, T., Jorgens, D. M., Nickerson, A., Lin, L. J., Pelz, J., Gray, J. W., López, C. S. & Nan, X., May 2017, In : PloS one. 12, 5, e0176839.

Research output: Contribution to journalArticle

14 Scopus citations

Quantitative, in situ analysis of mRNAs and proteins with subcellular resolution

Kwon, S., Chin, K-Y., Nederlof, M. & Gray, J., Dec 1 2017, In : Scientific Reports. 7, 1, 16459.

Research output: Contribution to journalArticle

2 Scopus citations

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis

Tsujikawa, T., Kumar, S., Borkar, R. N., Azimi, V., Thibault, G., Chang, Y. H., Balter, A., Kawashima, R., Choe, G., Sauer, D., El Rassi, E., Clayburgh, D., Kulesz-Martin, M., Lutz, E. R., Zheng, L., Jaffee, E. M., Leyshock, P., Margolin, A., Mori, M. T., Gray, J. & 2 others, Flint, P. & Coussens, L., Apr 4 2017, In : Cell Reports. 19, 1, p. 203-217 15 p.

Research output: Contribution to journalArticle

127 Scopus citations

Targeted treatment of metastatic breast cancer by PLK1 siRNA delivered by an antioxidant nanoparticle platform

Morry, J., Ngamcherdtrakul, W., Gu, S., Reda, M., Castro, D. J., Sangvanich, T., Gray, J. & Yantasee, W., Apr 1 2017, In : Molecular Cancer Therapeutics. 16, 4, p. 763-772 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., Kuleshov, M. V., Ma'ayan, A., Stathias, V., Terryn, R., Cooper, D., Forlin, M., Koleti, A., Vidovic, D., Chung, C., Schürer, S. C. & 87 others, Vasiliauskas, J., Pilarczyk, M., Shamsaei, B., Fazel, M., Ren, Y., Niu, W., Clark, N. A., White, S., Mahi, N., Zhang, L., Kouril, M., Reichard, J. F., Sivaganesan, S., Medvedovic, M., Meller, J., Koch, R. J., Birtwistle, M. R., Iyengar, R., Sobie, E. A., Azeloglu, E. U., Kaye, J., Osterloh, J., Haston, K., Kalra, J., Finkbiener, S., Li, J., Milani, P., Adam, M., Escalante-Chong, R., Sachs, K., Lenail, A., Ramamoorthy, D., Fraenkel, E., Daigle, G., Hussain, U., Coye, A., Rothstein, J., Sareen, D., Ornelas, L., Banuelos, M., Mandefro, B., Ho, R., Svendsen, C. N., Lim, R. G., Stocksdale, J., Casale, M. S., Thompson, T. G., Wu, J., Thompson, L. M., Dardov, V., Venkatraman, V., Matlock, A., Van Eyk, J. E., Jaffe, J. D., Papanastasiou, M., Subramanian, A., Golub, T. R., Erickson, S. D., Fallahi-Sichani, M., Hafner, M., Gray, N. S., Lin, J. R., Mills, C. E., Muhlich, J. L., Niepel, M., Shamu, C. E., Williams, E. H., Wrobel, D., Sorger, P. K., Heiser, L., Gray, J., Korkola, J., Mills, G., LaBarge, M., Feiler, H., Dane, M. A., Bucher, E., Nederlof, M., Sudar, D., Gross, S., Kilburn, D. F., Smith, R., Devlin, K., Margolis, R., Derr, L., Lee, A. & Pillai, A., Jan 1 2017, (Accepted/In press) In : Cell Systems.

Research output: Contribution to journalArticle

79 Scopus citations
2018

CCR5 Governs DNA damage repair and breast cancer stem cell expansion

Jiao, X., Velasco-Velazquez, M. A., Wang, M., Li, Z., Rui, H., Peck, A. R., Korkola, J. E., Chen, X., Xu, S., DuHadaway, J. B., Guerrero-Rodriguez, S., Addya, S., Sicoli, D., Mu, Z., Zhang, G., Stucky, A., Zhang, X., Cristofanilli, M., Fatatis, A., Gray, J. W. & 3 others, Zhong, J. F., Prendergast, G. C. & Pestell, R. G., Apr 1 2018, In : Cancer Research. 78, 7, p. 1657-1671 15 p.

Research output: Contribution to journalArticle

27 Scopus citations

Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival

Gast, C. E., Silk, A. D., Zarour, L., Riegler, L., Burkhart, J. G., Gustafson, K. T., Parappilly, M. S., Roh-Johnson, M., Goodman, J. R., Olson, B., Schmidt, M., Swain, J. R., Davies, P., Shasthri, V., Iizuka, S., Flynn, P., Watson, S., Korkola, J., Courtneidge, S., Fischer, J. & 8 others, Jaboin, J., Billingsley, K., Lopez, C., Burchard, J., Gray, J., Coussens, L., Sheppard, B. & Wong, M., Sep 12 2018, In : Science advances. 4, 9, eaat7828.

Research output: Contribution to journalArticle

40 Scopus citations