• 65500 Citations
  • 111 h-Index
1971 …2020
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Research Output 1971 2020

2006
68 Citations (Scopus)

Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells

Lorenzi, P. L., Reinhold, W. C., Rudelius, M., Gunsior, M., Shankavaram, U., Bussey, K. J., Scherf, U., Eichler, G. S., Martin, S. E., Chin, K-Y., Gray, J., Kohn, E. C., Horak, I. D., Von Hoff, D. D., Raffeld, M., Goldsmith, P. K., Caplen, N. J. & Weisntein, J. N., Nov 2006, In : Molecular Cancer Therapeutics. 5, 11, p. 2613-2623 11 p.

Research output: Contribution to journalArticle

Aspartate-Ammonia Ligase
Asparaginase
Ovarian Neoplasms
Biomarkers
Neoplasms
226 Citations (Scopus)

Breast tumor copy number aberration phenotypes and genomic instability

Fridlyand, J., Snijders, A. M., Ylstra, B., Li, H., Olshen, A., Segraves, R., Dairkee, S., Tokuyasu, T., Ljung, B. M., Jain, A. N., McLennan, J., Ziegler, J., Chin, K-Y., Devries, S., Feiler, H., Gray, J., Waldman, F., Pinkel, D. & Albertson, D. G., Apr 18 2006, In : BMC Cancer. 6, 96.

Research output: Contribution to journalArticle

Genomic Instability
Breast Neoplasms
Phenotype
Telomere
Neoplasms
118 Citations (Scopus)

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

Rai, R., Dai, H., Multani, A. S., Li, K., Chin, K-Y., Gray, J., Lahad, J. P., Liang, J., Mills, G., Meric-Bernstam, F. & Lin, S. Y., Aug 2006, In : Cancer Cell. 10, 2, p. 145-157 13 p.

Research output: Contribution to journalArticle

DNA Damage
Neoplasms
Genomic Instability
Tumor Suppressor Genes
Chromosome Aberrations
297 Citations (Scopus)

Cellular effect of high doses of silica-coated quantum dot profiled with high throughput gene expression analysis and high content cellomics measurements

Zhang, T., Stilwell, J. L., Gerion, D., Ding, L., Elboudwarej, O., Cooke, P. A., Gray, J., Alivisatos, A. P. & Chen, F. F., Apr 2006, In : Nano Letters. 6, 4, p. 800-808 9 p.

Research output: Contribution to journalArticle

gene expression
Gene expression
Silicon Dioxide
Polyethylene glycols
Semiconductor quantum dots
48 Citations (Scopus)

Decoding the fine-scale structure of a breast cancer genome and transcriptome

Volik, S., Raphael, B. J., Huang, G., Stratton, M. R., Bignel, G., Murnane, J., Brebner, J. H., Bajsarowicz, K., Paris, P. L., Tao, Q., Kowbel, D., Lapuk, A., Shagin, D. A., Shagina, I. A., Gray, J., Cheng, J. F., De Jong, P. J., Pevzner, P. & Collins, C., Mar 2006, In : Genome Research. 16, 3, p. 394-404 11 p.

Research output: Contribution to journalArticle

Transcriptome
Genome
Breast Neoplasms
Neoplasms
Clone Cells
11 Citations (Scopus)

EGFR intron 1 polymorphism in Asian populations and its correlation with EGFR gene expression and amplification in breast tumor tissues

Zhou, Q., Yin, B. C., Jada, S. R., Wan, T. L., Kuo, W. L., Gray, J., Lee, A. S. G. & Chowbay, B., Nov 2006, In : Cancer Biology and Therapy. 5, 11, p. 1445-1449 5 p.

Research output: Contribution to journalArticle

Dinucleotide Repeats
erbB-1 Genes
Gene Amplification
Introns
Breast Neoplasms
917 Citations (Scopus)

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

Chin, K-Y., DeVries, S., Fridlyand, J., Spellman, P., Roydasgupta, R., Kuo, W. L., Lapuk, A., Neve, R. M., Qian, Z., Ryder, T., Chen, F., Feiler, H., Tokuyasu, T., Kingsley, C., Dairkee, S., Meng, Z., Chew, K., Pinkel, D., Jain, A., Ljung, B. M. & 4 others, Esserman, L., Albertson, D. G., Waldman, F. M. & Gray, J., Dec 2006, In : Cancer Cell. 10, 6, p. 529-541 13 p.

Research output: Contribution to journalArticle

I-kappa B Kinase
Breast Neoplasms
Neoplasms
Genome
RNA
126 Citations (Scopus)

Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel

Bussey, K. J., Chin, K-Y., Lababidi, S., Reimers, M., Reinhold, W. C., Kuo, W. L., Gwadry, F., Ajay, Kouros-Mehr, H., Fridlyand, J., Jain, A., Collins, C., Nishizuka, S., Tonon, G., Roschke, A., Gehlhaus, K., Kirsch, I., Scudiero, D. A., Gray, J. & Weinstein, J. N., Apr 2006, In : Molecular Cancer Therapeutics. 5, 4, p. 853-867 15 p.

Research output: Contribution to journalArticle

Gene Expression
Cell Line
DNA
Asparaginase
Pharmaceutical Preparations
10 Citations (Scopus)

Magellan: A web based system for the integrated analysis of heterogeneous biological data and annotations; application to DNA copy number and expression data in ovarian cancer

Kingsley, C. B., Kuo, W. L., Polikoff, D., Berchuck, A., Gray, J. & Jain, A. N., 2006, In : Cancer Informatics. 2, p. 10-21 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Comparative Genomic Hybridization
DNA
Messenger RNA
Tidal Waves
271 Citations (Scopus)

Organic cation transporters are determinants of oxaliplatin cytotoxicity

Zhang, S., Lovejoy, K. S., Shima, J. E., Lagpacan, L. L., Shu, Y., Lapuk, A., Chen, Y., Komori, T., Gray, J., Chen, X., Lippard, S. J. & Giacomini, K. M., Sep 1 2006, In : Cancer Research. 66, 17, p. 8847-8857 11 p.

Research output: Contribution to journalArticle

oxaliplatin
Cations
Cisplatin
Platinum
Carboplatin
53 Citations (Scopus)

Prognostic value of PAI1 in invasive breast cancer: Evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression

Sternlicht, M. D., Dunning, A. M., Moore, D. H., Pharoah, P. D. P., Ginzinger, D. G., Chin, K-Y., Gray, J., Waldman, F. M., Ponder, B. A. J. & Werb, Z., Nov 2006, In : Cancer Epidemiology Biomarkers and Prevention. 15, 11, p. 2107-2114 8 p.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Breast Neoplasms
Neoplasms
Connective Tissue Growth Factor
Messenger RNA
144 Citations (Scopus)

Qdot nanobarcodes for multiplexed gene expression analysis

Eastman, P. S., Ruan, W., Doctolero, M., Nuttall, R., De Feo, G., Park, J. S., Chu, J. S. F., Cooke, P., Gray, J., Li, S. & Chen, F. F., May 2006, In : Nano Letters. 6, 5, p. 1059-1064 6 p.

Research output: Contribution to journalArticle

gene expression
Microarrays
Gene expression
Complementary RNA
Semiconductor quantum dots
241 Citations (Scopus)

β1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo

Park, C. C., Zhang, H., Pallavicini, M., Gray, J., Baehner, F., Park, C. J. & Bissell, M. J., Feb 1 2006, In : Cancer Research. 66, 3, p. 1526-1535 10 p.

Research output: Contribution to journalArticle

Integrins
Apoptosis
Breast Neoplasms
Phenotype
Antibodies
2007
44 Citations (Scopus)

Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers.

Yau, C., Fedele, V., Roydasgupta, R., Fridlyand, J., Hubbard, A., Gray, J., Chew, K., Dairkee, S. H., Moore, D. H., Schittulli, F., Tommasi, S., Paradiso, A., Albertson, D. G. & Benz, C. C., 2007, In : Breast cancer research : BCR. 9, 5

Research output: Contribution to journalArticle

Transcriptome
Genome
Hormones
Breast Neoplasms
Estrogen Receptors
87 Citations (Scopus)

Amplification of MDS1/EVI1 and EVI1, located in the 3q26.2 amplicon, is associated with favorable patient prognosis in ovarian cancer

Nanjundan, M., Nakayama, Y., Kwai, W. C., Lahad, J., Liu, J., Lu, K., Kuo, W. L., Smith-McCune, K., Fishman, D., Gray, J. & Mills, G., Apr 1 2007, In : Cancer Research. 67, 7, p. 3074-3084 11 p.

Research output: Contribution to journalArticle

Virus Integration
Myelodysplastic Syndromes
Ovarian Neoplasms
DNA
Bacterial Artificial Chromosomes
255 Citations (Scopus)

Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer

Guan, Y., Kuo, W. L., Stilwell, J. L., Takano, H., Lapuk, A. V., Fridlyand, J., Mao, J. H., Yu, M., Miller, M. A., Santos, J. L., Kalloger, S. E., Carlson, J. W., Ginzinger, D. G., Celniker, S. E., Mills, G., Huntsman, D. G. & Gray, J., Oct 1 2007, In : Clinical Cancer Research. 13, 19, p. 5745-5755 11 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Breast Neoplasms
Cell Line
Small Interfering RNA
Untranslated RNA
48 Citations (Scopus)

Analysis of molecular inversion probe performance for allele copy number determination

Wang, Y., Moorhead, M., Karlin-Neumann, G., Wang, N. J., Ireland, J., Lin, S., Chen, C., Heiser, L., Chin, K-Y., Esserman, L., Gray, J., Spellman, P. & Faham, M., Nov 20 2007, In : Genome Biology. 8, 11, R246.

Research output: Contribution to journalArticle

Molecular Probes
allele
Alleles
probe
alleles
45 Citations (Scopus)

Assessing human germ-cell mutagenesis in the postgenome era: A celebration of the legacy of William Lawson (Bill) Russell

Wyrobek, A. J., Mulvihill, J. J., Wassom, J. S., Malling, H. V., Shelby, M. D., Lewis, S. E., Witt, K. L., Preston, R. J., Perreault, S. D., Allen, J. W., DeMarini, D. M., Woychik, R. P., Bishop, J. B., Anderson, D., Arnheim, N., Boice, J. D., Bridges, B. A., Crow, J. F., Dubrova, Y. E., Eichenlaub-Ritter, U. & 16 others, Erickson, R. P., Fridlyand, J., Gray, J., Hanawalt, P. C., Handel, M. A., Marchetti, F., Mohrenweiser, H. W., Moyzis, R. K., Primig, M., Russell, L. B., Sankaranarayanan, K., Skinner, M. K., Shoubridge, E. A., Taylor, J. A., Trasler, J. M. & Vasicek, T. J., Feb 2007, In : Environmental and Molecular Mutagenesis. 48, 2, p. 71-95 25 p.

Research output: Contribution to journalArticle

Mutagenesis
germ cell
Mutagens
Germ Cells
Animals
56 Citations (Scopus)

Crosstalk between Aurora-A and p53: Frequent Deletion or Downregulation of Aurora-A in Tumors from p53 Null Mice

Mao, J. H., Wu, D., Perez-Losada, J., Jiang, T., Li, Q., Neve, R. M., Gray, J., Cai, W. W. & Balmain, A., Feb 13 2007, In : Cancer Cell. 11, 2, p. 161-173 13 p.

Research output: Contribution to journalArticle

Down-Regulation
Aurora Kinase A
Lymphoma
Neoplasms
Gene Deletion
61 Citations (Scopus)

Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer

Climent, J., Dimitrow, P., Fridlyand, J., Palacios, J., Siebert, R., Albertson, D. G., Gray, J., Pinkel, D., Lluch, A. & Martinez-Climent, J. A., Jan 15 2007, In : Cancer Research. 67, 2, p. 818-826 9 p.

Research output: Contribution to journalArticle

Chromosome Deletion
Anthracyclines
Breast Neoplasms
Drug Therapy
Bacterial Artificial Chromosomes
138 Citations (Scopus)

Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer

Zhou, Y., Yau, C., Gray, J., Chew, K., Dairkee, S. H., Moore, D. H., Eppenberger, U., Eppenberger-Castori, S. & Benz, C. C., 2007, In : BMC Cancer. 7, 59.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Transcription Factor AP-1
Tamoxifen
Estrogen Receptors
Breast Neoplasms
13 Citations (Scopus)

Gamma-normal-gamma mixture model for detecting differentially methylated loci in three breast cancer cell lines

Khalili, A., Potter, D., Yan, P., Li, L., Gray, J., Huang, T. & Lin, S., 2007, In : Cancer Informatics. 3, p. 43-54 12 p.

Research output: Contribution to journalArticle

Methylation
Breast Neoplasms
Cell Line
CpG Islands
Statistical Models
40 Citations (Scopus)

Multiple roles of the candidate oncogene ZNF217 in ovarian epithelial neoplastic progression

Li, P., Maines-Bandiera, S., Kuo, W. L., Guan, Y., Sun, Y., Hills, M., Huang, G., Collins, C. C., Leung, P. C. K., Gray, J. & Auersperg, N., May 1 2007, In : International Journal of Cancer. 120, 9, p. 1863-1873 11 p.

Research output: Contribution to journalArticle

Oncogenes
Epithelial Cells
Cadherins
Epidermal Growth Factor
Ovarian Neoplasms

Nanobarcode gene expression monitoring system for potential miniaturized space applications

Ruan, W., Eastman, P. S., Cooke, P. A., Park, J. S., Chu, J. S. F., Gray, J., Li, S. & Chen, F. F., 2007, In : Advances in Space Research. 40, 4, p. 513-522 10 p.

Research output: Contribution to journalArticle

astronauts
gene expression
Space applications
Gene expression
monitoring system
73 Citations (Scopus)

Paramagnetic silica-coated nangcrystals as an advanced MRI contrast agent

Gerion, D., Herberg, J., Bok, R., Gjersing, E., Ramon, E., Maxwell, R., Kurhanewicz, J., Budinger, T. F., Gray, J., Shuman, M. A. & Chen, F. F., Aug 30 2007, In : Journal of Physical Chemistry C. 111, 34, p. 12542-12551 10 p.

Research output: Contribution to journalArticle

Magnetic resonance
Silicon Dioxide
Contrast Media
magnetic resonance
Silica

Spectral decomposition of signaling networks

Parvin, B., Ghosh, N., Heiser, L., Knapp, M., Talcott, C., Laderoute, K., Gray, J. & Spellman, P., 2007, 2007 IEEE Symposium on Computational Intelligence and Bioinformatics and Computational Biology, CIBCB 2007. p. 76-81 6 p. 4221207

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Decomposition
Proteins
Petri nets
Directed graphs
Cells
10 Citations (Scopus)

Systems biology in cancer research: genomics to cellomics.

Stilwell, J. L., Guan, Y., Neve, R. M. & Gray, J., 2007, In : Methods in molecular biology (Clifton, N.J.). 356, p. 353-365 13 p.

Research output: Contribution to journalArticle

Systems Biology
Genomics
Bromodeoxyuridine
Apoptosis
Research
589 Citations (Scopus)

The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression

Kenny, P. A., Lee, G. Y., Myers, C. A., Neve, R. M., Semeiks, J. R., Spellman, P., Lorenz, K., Lee, E. H., Barcellos-Hoff, M. H., Petersen, O. W., Gray, J. & Bissell, M. J., Jun 2007, In : Molecular Oncology. 1, 1, p. 84-96 13 p.

Research output: Contribution to journalArticle

Transcriptome
Breast Neoplasms
Cell Line
Cell Culture Techniques
Cultured Tumor Cells
2008
106 Citations (Scopus)

A human breast cell model of preinvasive to invasive transition

Rizki, A., Weaver, V. M., Lee, S. Y., Rozenberg, G. I., Chin, K-Y., Myers, C. A., Bascom, J. L., Mott, J. D., Semeiks, J. R., Grate, L. R., Mian, I. S., Borowsky, A. D., Jensen, R. A., Idowu, M. O., Chen, F., Chen, D. J., Petersen, O. W., Gray, J. & Bissell, M. J., Mar 1 2008, In : Cancer Research. 68, 5, p. 1378-1387 10 p.

Research output: Contribution to journalArticle

Breast
Phenotype
Matrix Metalloproteinases
Basement Membrane
Breast Neoplasms
92 Citations (Scopus)

Amplification of 11q13 in ovarian carcinoma

Brown, L. A., Kalloger, S. E., Miller, M. A., Shih, L. M., McKinney, S. E., Santos, J. L., Swenerton, K., Spellman, P., Gray, J., Gilks, C. B. & Huntsman, D. G., Jun 2008, In : Genes Chromosomes and Cancer. 47, 6, p. 481-489 9 p.

Research output: Contribution to journalArticle

Oncogenes
Ovarian Neoplasms
Carcinoma
Genes
Histology
648 Citations (Scopus)

An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

Stemke-Hale, K., Gonzalez-Angulo, A. M., Lluch, A., Neve, R. M., Kuo, W. L., Davies, M., Carey, M., Hu, Z., Guan, Y., Sahin, A., Symmans, W. F., Pusztai, L., Nolden, L. K., Horlings, H., Berns, K., Hung, M. C., Van De Vijver, M. J., Valero, V., Gray, J., Bernards, R. & 2 others, Mills, G. & Hennessy, B. T., Aug 1 2008, In : Cancer Research. 68, 15, p. 6084-6091 8 p.

Research output: Contribution to journalArticle

Proteomics
Phosphatidylinositol 3-Kinase
Breast Neoplasms
Mutation
Hormones
31 Citations (Scopus)

A sequence-based survey of the complex structural organization of tumor genomes

Raphael, B. J., Volik, S., Yu, P., Wu, C., Huang, G., Linardopoulou, E. V., Trask, B. J., Waldman, F., Costello, J., Pienta, K. J., Mills, G., Bajsarowicz, K., Kobayashi, Y., Sridharan, S., Paris, P. L., Tao, Q., Aerni, S. J., Brown, R. P., Bashir, A., Gray, J. & 6 others, Cheng, J. F., de Jong, P., Nefedov, M., Ried, T., Padilla-Nash, H. M. & Collins, C. C., Mar 25 2008, In : Genome Biology. 9, 3, R59.

Research output: Contribution to journalArticle

tumor
genome
Genome
neoplasms
Neoplasms

Cancer Genomics

Spellman, P., Costello, J. F. & Gray, J., 2008, The Molecular Basis of Cancer. Elsevier Inc., p. 267-282 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genomics
Neoplasms
4536 Citations (Scopus)

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

McLendon, R., Friedman, A., Bigner, D., Van Meir, E. G., Brat, D. J., Mastrogianakis, G. M., Olson, J. J., Mikkelsen, T., Lehman, N., Aldape, K., Yung, W. K. A., Bogler, O., Weinstein, J. N., VandenBerg, S., Berger, M., Prados, M., Muzny, D., Morgan, M., Scherer, S., Sabo, A. & 211 others, Nazareth, L., Lewis, L., Hall, O., Zhu, Y., Ren, Y., Alvi, O., Yao, J., Hawes, A., Jhangiani, S., Fowler, G., San Lucas, A., Kovar, C., Cree, A., Dinh, H., Santibanez, J., Joshi, V., Gonzalez-Garay, M. L., Miller, C. A., Milosavljevic, A., Donehower, L., Wheeler, D. A., Gibbs, R. A., Cibulskis, K., Sougnez, C., Fennell, T., Mahan, S., Wilkinson, J., Ziaugra, L., Onofrio, R., Bloom, T., Nicol, R., Ardlie, K., Baldwin, J., Gabriel, S., Lander, E. S., Ding, L., Fulton, R. S., McLellan, M. D., Wallis, J., Larson, D. E., Shi, X., Abbott, R., Fulton, L., Chen, K., Koboldt, D. C., Wendl, M. C., Meyer, R., Tang, Y., Lin, L., Osborne, J. R., Dunford-Shore, B. H., Miner, T. L., Delehaunty, K., Markovic, C., Swift, G., Courtney, W., Pohl, C., Abbott, S., Hawkins, A., Leong, S., Haipek, C., Schmidt, H., Wiechert, M., Vickery, T., Scott, S., Dooling, D. J., Chinwalla, A., Weinstock, G. M., Mardis, E. R., Wilson, R. K., Getz, G., Winckler, W., Verhaak, R. G. W., Lawrence, M. S., O'Kelly, M., Robinson, J., Alexe, G., Beroukhim, R., Carter, S., Chiang, D., Gould, J., Gupta, S., Korn, J., Mermel, C., Mesirov, J., Monti, S., Nguyen, H., Parkin, M., Reich, M., Stransky, N., Weir, B. A., Garraway, L., Golub, T., Meyerson, M., Chin, L., Protopopov, A., Zhang, J., Perna, I., Aronson, S., Sathiamoorthy, N., Ren, G., Yao, J., Wiedemeyer, W. R., Kim, H., Sek, W. K., Xiao, Y., Kohane, I. S., Seidman, J., Park, P. J., Kucherlapati, R., Laird, P. W., Cope, L., Herman, J. G., Weisenberger, D. J., Pan, F., Van Den Berg, D., Van Neste, L., Joo, M. Y., Schuebel, K. E., Baylin, S. B., Absher, D. M., Li, J. Z., Southwick, A., Brady, S., Aggarwal, A., Chung, T., Sherlock, G., Brooks, J. D., Myers, R. M., Spellman, P., Purdom, E., Jakkula, L. R., Lapuk, A. V., Marr, H., Dorton, S., Yoon, G. C., Han, J., Ray, A., Wang, V., Durinck, S., Robinson, M., Wang, N. J., Vranizan, K., Peng, V., Van Name, E., Fontenay, G. V., Ngai, J., Conboy, J. G., Parvin, B., Feiler, H., Speed, T. P., Gray, J., Brennan, C., Socci, N. D., Olshen, A., Taylor, B. S., Lash, A., Schultz, N., Reva, B., Antipin, Y., Stukalov, A., Gross, B., Cerami, E., Wei, Q. W., Qin, L. X., Seshan, V. E., Villafania, L., Cavatore, M., Borsu, L., Viale, A., Gerald, W., Sander, C., Ladanyi, M., Perou, C. M., Hayes, D. N., Topal, M. D., Hoadley, K. A., Qi, Y., Balu, S., Shi, Y., Wu, J., Penny, R., Bittner, M., Shelton, T., Lenkiewicz, E., Morris, S., Beasley, D., Sanders, S., Kahn, A., Sfeir, R., Chen, J., Nassau, D., Feng, L., Hickey, E., Barker, A., Gerhard, D. S., Vockley, J., Compton, C., Vaught, J., Fielding, P., Ferguson, M. L., Schaefer, C., Zhang, J., Madhavan, S., Buetow, K. H., Collins, F., Good, P., Guyer, M., Ozenberger, B., Peterson, J. & Thomson, E., Oct 23 2008, In : Nature. 455, 7216, p. 1061-1068 8 p.

Research output: Contribution to journalArticle

Glioblastoma
Atlases
Genes
DNA Methylation
Neoplasms
524 Citations (Scopus)

Dicer, Drosha, and outcomes in patients with ovarian cancer

Merritt, W. M., Lin, Y. G., Han, L. Y., Kamat, A. A., Spannuth, W. A., Schmandt, R., Urbauer, D., Pennacchio, L. A., Cheng, J. F., Nick, A. M., Deavers, M. T., Mourad-Zeidan, A., Wang, H., Mueller, P., Lenburg, M. E., Gray, J., Mok, S., Birrer, M. J., Lopez-Berestein, G., Coleman, R. L. & 2 others, Bar-Eli, M. & Sood, A. K., Dec 18 2008, In : New England Journal of Medicine. 359, 25, p. 2641-2650 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Small Interfering RNA
DNA Mutational Analysis
Messenger RNA
RNA Interference
49 Citations (Scopus)

ESR1 gene amplification in breast cancer: A common phenomenon? [1]

Brown, L. A., Hoog, J., Chin, S. F., Tao, Y., Zayed, A. A., Chin, K-Y., Teschendorff, A. E., Quackenbush, J. F., Marioni, J. C., Leung, S., Perou, C. M., Neilsen, T. O., Ellis, M., Gray, J., Bernard, P. S., Huntsman, D. G. & Caldas, C., Jul 2008, In : Nature Genetics. 40, 7, p. 806-807 2 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Ovarian cancer: Linking genomics to new target discovery and molecular markers - The way ahead

Hennessy, B. T., Murph, M., Nanjundan, M., Carey, M., Auersperg, N., Almeida, J., Coombes, K. R., Liu, J., Lu, Y., Gray, J. & Mills, G., 2008, Advances in Experimental Medicine and Biology. Vol. 617. p. 23-40 18 p. (Advances in Experimental Medicine and Biology; vol. 617).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Human Genome
Tumor Biomarkers
Genomics
Ovarian Neoplasms
221 Citations (Scopus)

Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities

Press, J. Z., De Luca, A., Boyd, N., Young, S., Troussard, A., Ridge, Y., Kaurah, P., Kalloger, S. E., Blood, K. A., Smith, M., Spellman, P., Wang, Y., Miller, D. M., Horsman, D., Faham, M., Gilks, C. B., Gray, J. & Huntsman, D. G., Jan 22 2008, In : BMC Cancer. 8, 17.

Research output: Contribution to journalArticle

Epigenomics
Carcinoma
Mutation
Loss of Heterozygosity
Ovarian Neoplasms
22 Citations (Scopus)

Overexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: A role in ovarian pathogenesis

Nanjundan, M., Cheng, K. W., Zhang, F., Lahad, J., Kuo, W. L., Schmandt, R., Smith-McCune, K., Fishman, D., Gray, J. & Mills, G., Aug 2008, In : Molecular Oncology. 2, 2, p. 164-181 18 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
RNA
Carcinogenesis
Growth
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
1 Citation (Scopus)

Preface

Mendelsohn, J., Howley, P. M., Israel, M. A., Gray, J. & Thompson, C. B., 2008, In : Unknown Journal.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature

Tutt, A., Wang, A., Rowland, C., Gillett, C., Lau, K., Chew, K., Dai, H., Kwok, S., Ryder, K., Shu, H., Springall, R., Cane, P., McCallie, B., Kam-Morgan, L., Anderson, S., Buerger, H., Gray, J., Bennington, J., Esserman, L., Hastie, T. & 4 others, Broder, S., Sninsky, J., Brandt, B. & Waldman, F., Nov 21 2008, In : BMC Cancer. 8, 339.

Research output: Contribution to journalArticle

Estrogen Receptors
Breast Neoplasms
Neoplasm Metastasis
Polymerase Chain Reaction
Survival
16 Citations (Scopus)

The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas

Sun, Y., Wong, N., Guan, Y., Salamanca, C. M., Jung, C. C., Lee, J. M., Gray, J. & Auersperg, N., Oct 15 2008, In : International Journal of Cancer. 123, 8, p. 1761-1769 9 p.

Research output: Contribution to journalArticle

Peptide Elongation Factors
Apoptosis
Carcinoma
Oncogenes
Small Interfering RNA
28 Citations (Scopus)

The Molecular Basis of Cancer

Mendelsohn, J., Howley, P. M., Israel, M. A., Gray, J. & Thompson, C. B., 2008, Elsevier Inc.

Research output: Book/ReportBook

Color
Gene therapy
Biotechnology
Websites
Neoplasms
215 Citations (Scopus)

Translating insights from the cancer genome into clinical practice

Chin, L. & Gray, J., Apr 3 2008, In : Nature. 452, 7187, p. 553-563 11 p.

Research output: Contribution to journalArticle

Genome
Neoplasms
Epigenomics
Atlases
Noise
25 Citations (Scopus)

Translational Research Working Group developmental pathway for biospecimen-based assessment modalities

Srivastava, S., Gray, J., Reid, B. J., Grad, O., Greenwood, A. & Hawk, E. T., Sep 15 2008, In : Clinical Cancer Research. 14, 18, p. 5672-5677 6 p.

Research output: Contribution to journalArticle

Translational Medical Research
Biomarkers
National Cancer Institute (U.S.)
Neoplasms
2009
13 Citations (Scopus)

A primer on regression methods for decoding cis-regulatory logic

Das, D., Pellegrini, M. & Gray, J., Jan 2009, In : PLoS Computational Biology. 5, 1, e1000269.

Research output: Contribution to journalArticle

Gene expression regulation
Transcriptional Regulatory Elements
Transcription factors
Nonlinear Dynamics
Genetic Models
24 Citations (Scopus)

A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047

Kuo, W. L., Das, D., Ziyad, S., Bhattacharya, S., Gibb, W. J., Heiser, L., Sadanandam, A., Fontenay, G. V., Hu, Z., Wang, N. J., Bayani, N., Feiler, H., Neve, R. M., Wyrobek, A. J., Spellman, P., Marton, L. J. & Gray, J., Dec 14 2009, In : BMC Medicine. 7, 77.

Research output: Contribution to journalArticle

Polyamines
Systems Analysis
Breast Neoplasms
Cell Line
Breast
269 Citations (Scopus)

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

Mirzoeva, O. K., Das, D., Heiser, L., Bhattacharya, S., Siwak, D., Gendelman, R., Bayani, N., Wang, N. J., Neve, R. M., Guan, Y., Hu, Z., Knight, Z., Feiler, H., Gascard, P., Parvin, B., Spellman, P., Shokat, K. M., Wyrobek, A. J., Bissell, M. J., McCormick, F. & 4 others, Kuo, W. L., Mills, G., Gray, J. & Korn, W. M., Jan 15 2009, In : Cancer Research. 69, 2, p. 565-572 8 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Mitogen-Activated Protein Kinase Kinases
Extracellular Signal-Regulated MAP Kinases
Phosphotransferases
Breast Neoplasms
574 Citations (Scopus)

Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

Hennessy, B. T., Gonzalez-Angulo, A. M., Stemke-Hale, K., Gilcrease, M. Z., Krishnamurthy, S., Lee, J. S., Fridlyand, J., Sahin, A., Agarwal, R., Joy, C., Liu, W., Stivers, D., Baggerly, K., Carey, M., Lluch, A., Monteagudo, C., He, X., Weigman, V., Fan, C., Palazzo, J. & 7 others, Hortobagyi, G. N., Nolden, L. K., Wang, N. J., Valero, V., Gray, J., Perou, C. M. & Mills, G., May 15 2009, In : Cancer Research. 69, 10, p. 4116-4124 9 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Mesenchymal Stromal Cells
Breast Neoplasms
Neoplasms
Neoplastic Stem Cells
85 Citations (Scopus)

Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts

Hodgson, J. G., Yeh, R. F., Ray, A., Wang, N. J., Smirnov, I., Yu, M., Hariono, S., Silber, J., Feiler, H., Gray, J., Spellman, P., Vandenberg, S. R., Berger, M. S. & James, C. D., Oct 2009, In : Neuro-Oncology. 11, 5, p. 477-487 11 p.

Research output: Contribution to journalArticle

Gene Dosage
Glioblastoma
Heterografts
Messenger RNA
Neoplasms