• 68549 Citations
  • 113 h-Index
1971 …2020

Research output per year

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Research Output

2002

Increased risk of local recurrence is associated with allelic loss in normal lobules of breast cancer patients

Li, Z., Moore, D. H., Meng, Z. H., Dairkee, S. H., Ljung, B. M. & Gray, J. W., Feb 15 2002, In : Cancer Research. 62, 4, p. 1000-1003 4 p.

Research output: Contribution to journalArticle

52 Scopus citations

Technical approaches for efficient, high precision nucleic acid analysis using DNA microarrays

Pinkel, D., Hamilton, G., Brown, N., Segraves, R., Huey, B., Snijders, A., Blackwood, S., Hindle, K., Law, S., Gray, J., Jain, A., Hanson, J., Nordmeyer, R. & Albertson, D., Jan 1 2002, In : Proceedings of SPIE-The International Society for Optical Engineering. 4626, p. 82-88 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2003

Chromosome aberrations in solid tumors

Albertson, D. G., Collins, C., McCormick, F. & Gray, J. W., Aug 1 2003, In : Nature genetics. 34, 4, p. 369-376 8 p.

Research output: Contribution to journalReview article

583 Scopus citations

End-sequence profiling: Sequence-based analysis of aberrant genomes

Volik, S., Zhao, S., Chin, K., Brebner, J. H., Herndon, D. R., Tao, Q., Kowbel, D., Huang, G., Lapuk, A., Kuo, W. L., Magrane, G., De Jong, P., Gray, J. W. & Collins, C., Jun 24 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 13, p. 7696-7701 6 p.

Research output: Contribution to journalArticle

111 Scopus citations

Evidence emerges for early metastasis and parallel evolution of primary and metastatic tumors

Gray, J. W., Jul 1 2003, In : Cancer Cell. 4, 1, p. 4-6 3 p.

Research output: Contribution to journalReview article

80 Scopus citations

Genome amplification of chromosome 20 in breast cancer

Hodgson, J. G., Chin, K., Collins, C. & Gray, J. W., Apr 1 2003, In : Breast Cancer Research and Treatment. 78, 3, p. 337-345 9 p.

Research output: Contribution to journalReview article

81 Scopus citations

Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors

Hackett, C. S., Hodgson, J. G., Law, M. E., Fridlyand, J., Osoegawa, K., De Jong, P. J., Nowak, N. J., Pinkel, D., Albertson, D. G., Jain, A., Jenkins, R., Gray, J. W. & Weiss, W. A., Sep 1 2003, In : Cancer Research. 63, 17, p. 5266-5273 8 p.

Research output: Contribution to journalArticle

89 Scopus citations

Induction of tumors in mice by genomic hypomethylation

Gaudet, F., Hodgson, J. G., Eden, A., Jackson-Grusby, L., Dausman, J., Gray, J. W., Leonhardt, H. & Jaenisch, R., Apr 18 2003, In : Science. 300, 5618, p. 489-492 4 p.

Research output: Contribution to journalArticle

1123 Scopus citations

In Situ Quantification of Genomic Instability in Breast Cancer Progression

Ortiz De Solórzano, C., Chin, K., Gray, J. W. & Lockett, S. J., Dec 1 2003, In : Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 4, p. 3578-3581 4 p.

Research output: Contribution to journalConference article

Linking Molecular Diagnostics to Molecular Therapeutics: Targeting the PI3K Pathway in Breast Cancer

Mills, G. B., Kohn, E., Lu, Y., Eder, A., Fang, X., Wang, H., Bast, R. C., Gray, J., Jaffe, R. & Hortobagyi, G., Oct 2003, In : Seminars in Oncology. 30, 5 SUPPL. 16, p. 93-104 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Specific keynote: genome copy number abnormalities in ovarian cancer.

Gray, J. W., Suzuki, S., Kuo, W. L., Polikoff, D., Deavers, M., Smith-McCune, K., Berchuck, A., Pinkel, D., Albertson, D. & Mills, G. B., Jan 2003, In : Gynecologic oncology. 88, 1 Pt 2, p. S16-21; discussion S22-24

Research output: Contribution to journalReview article

35 Scopus citations

Specific keynote: molecular therapeutics in ovarian cancer.

Mills, G. B., Fang, X., Lu, Y., Hasegawa, Y., Eder, A., Tanyi, J., Tabassam, F. H., Mao, M., Wang, H., Cheng, K. W., Nakayama, Y., Kuo, W., Erickson, J., Gershenson, D., Kohn, E. C., Jaffe, R., Bast, R. C. & Gray, J., Jan 2003, In : Gynecologic oncology. 88, 1 Pt 2, p. S88-92; discussion S93-96

Research output: Contribution to journalReview article

18 Scopus citations

The genetics and genomics of cancer

Balmain, A., Gray, J. & Ponder, B., Mar 2003, In : Nature genetics. 33, 3S, p. 238-244 7 p.

Research output: Contribution to journalReview article

437 Scopus citations

Translating laboratory knowledge into biological therapy and genetic analysis

Gray, J., Jan 1 2003, In : Breast Journal. 9, SUPPL. 1, p. S29-S31

Research output: Contribution to journalArticle

2004

Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes

Argilla, D., Chin, K., Singh, M., Hodgson, J. G., Bosenberg, M., De Solórzano, C. O., Lockett, S., DePinho, R. A., Gray, J. & Hanahan, D., Oct 2004, In : Cancer Cell. 6, 4, p. 373-385 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

An Integrated View of Copy Number and Allelic Alterations in the Cancer Genome Using Single Nucleotide Polymorphism Arrays

Zhao, X., Li, C., Paez, J. G., Chin, K., Jänne, P. A., Chen, T. H., Girard, L., Minna, J., Christiani, D., Leo, C., Gray, J. W., Sellers, W. R. & Meyerson, M., May 1 2004, In : Cancer Research. 64, 9, p. 3060-3071 12 p.

Research output: Contribution to journalArticle

435 Scopus citations

Array comparative genomic hybridization with cyanin cis-platinum-labeled DNAs

Raap, A. K., Van Der Burg, M. J. M., Knijnenburg, J., Meershoek, E., Rosenberg, C., Gray, J. W., Wiegant, J., Hodgson, J. G. & Tanke, H. J., Jul 2004, In : BioTechniques. 37, 1, p. 130-134 5 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
125 Scopus citations

Computational BAC Clone Contig Assembly for Comprehensive Genome Analysis

Lapuk, A., Volik, S., Vincent, R., Chin, K., Kuo, W. L., De Jong, P., Collins, C. & Gray, J. W., May 1 2004, In : Genes Chromosomes and Cancer. 40, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cytometry and Genetics

Cram, L. S., Gray, J. W. & Carter, N. P., Mar 2004, In : Cytometry Part A. 58, 1, p. 33-36 4 p.

Research output: Contribution to journalReview article

4 Scopus citations

Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma

Sonoda, I., Imoto, I., Inoue, J., Shibata, T., Shimada, Y., Chin, K., Imamura, M., Amagasa, T., Gray, J. W., Hirohashi, S. & Inazawa, J., Jun 1 2004, In : Cancer Research. 64, 11, p. 3741-3747 7 p.

Research output: Contribution to journalArticle

107 Scopus citations

In situ analyses of genome instability in breast cancer

Chin, K., De Solorzano, C. O., Knowles, D., Jones, A., Chou, W., Rodriguez, E. G., Kuo, W. L., Ljung, B. M., Chew, K., Myambol, K., Miranda, M., Krig, S., Garbe, J., Stampfer, M., Yaswen, P., Gray, J. W. & Lockett, S. J., Sep 1 2004, In : Nature genetics. 36, 9, p. 984-988 5 p.

Research output: Contribution to journalArticle

291 Scopus citations

Oncogene Expression and Genetic Background Influence the Frequency of DNA Copy Number Abnormalities in Mouse Pancreatic Islet Cell Carcinomas

Hager, J. H., Hodgson, J. G., Fridlyand, J., Hariono, S., Gray, J. W. & Hanahan, D., Apr 1 2004, In : Cancer Research. 64, 7, p. 2406-2410 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability

Scacheri, P. C., Kennedy, A. L., Chin, K., Miller, M. T., Hodgson, J. G., Gray, J. W., Marx, S. J., Spiegel, A. M. & Collins, F. S., Oct 1 2004, In : Cancer Research. 64, 19, p. 7039-7044 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Reconstruction of functionally normal and malignant human breast tissues in mice

Kuperwasser, C., Chavarria, T., Wu, M., Magrane, G., Gray, J. W., Carey, L., Richardson, A. & Weinberg, R. A., Apr 6 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 14, p. 4966-4971 6 p.

Research output: Contribution to journalArticle

595 Scopus citations

TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines

Fan, W., Huang, X., Chen, C., Gray, J. & Huang, T., Aug 1 2004, In : Cancer Research. 64, 15, p. 5132-5139 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

Cheng, K. W., Lahad, J. P., Kuo, W. L., Lapuk, A., Yamada, K., Auersperg, N., Liu, J., Smith-McCune, K., Lu, K. H., Fishman, D., Gray, J. W. & Mills, G. B., Nov 1 2004, In : Nature medicine. 10, 11, p. 1251-1256 6 p.

Research output: Contribution to journalArticle

383 Scopus citations

The Role of p53 in Suppression of KSHV Cyclin-induced Lymphomagenesis

Verschuren, E. W., Hodgson, J. G., Gray, J. W., Kogan, S., Jones, N. & Evan, G. I., Jan 15 2004, In : Cancer Research. 64, 2, p. 581-589 9 p.

Research output: Contribution to journalArticle

68 Scopus citations
2005

A conditional feedback loop regulates Ras activity through EphA2

Macrae, M., Neve, R. M., Rodriguez-Viciana, P., Haqq, C., Yeh, J., Chen, C., Gray, J. W. & McCormick, F., Aug 1 2005, In : Cancer Cell. 8, 2, p. 111-118 8 p.

Research output: Contribution to journalArticle

168 Scopus citations

Array-based comparative genomic hybridization analysis identified cyclin D1 as a target oncogene at 11q13.3 in nasopharyngeal carcinoma

Hui, A. B. Y., Or, Y. Y. Y., Takano, H., Tsang, R. K. Y., To, K. F., Guan, X. Y., Sham, J. S. T., Hung, K. W. K., Lam, C. N. Y., Van Hasselt, C. A., Kuo, W. L., Gray, J. W., Huang, D. P. & Lo, K. W., Sep 15 2005, In : Cancer Research. 65, 18, p. 8125-8133 9 p.

Research output: Contribution to journalArticle

86 Scopus citations

Atypical PKCι contributes to poor prognosis through loss of apical-basal polarity and Cyclin E overexpression in ovarian cancer

Eder, A. M., Sui, X., Rosen, D. G., Nolden, L. K., Cheng, K. W., Lahad, J. P., Kango-Singh, M., Lu, K. H., Warneke, C. L., Atkinson, E. M., Bedrosian, I., Keyomarsi, K., Kuo, W. L., Gray, J. W., Yin, J. C. P., Liu, J., Halder, G. & Mills, G. B., Aug 30 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 35, p. 12519-12524 6 p.

Research output: Contribution to journalArticle

199 Scopus citations

Copy number aberrations in mouse breast tumors reveal loci and genes important in tumorigenic receptor tyrosine kinase signaling

Hodgson, J. G., Malek, T., Bornstein, S., Hariono, S., Ginzinger, D. G., Muller, W. J. & Gray, J. W., Nov 1 2005, In : Cancer Research. 65, 21, p. 9695-9704 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Design considerations for array CGH to oligonucleotide arrays

Baldocchi, R. A., Glynne, R. J., Chin, K., Kowbel, D., Collins, C., Mack, D. H. & Gray, J. W., Oct 2005, In : Cytometry Part A. 67, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Emerging role of RAB GTPases in cancer and human disease

Cheng, K. W., Lahad, J. P., Gray, J. W. & Mills, G. B., Apr 1 2005, In : Cancer Research. 65, 7, p. 2516-2519 4 p.

Research output: Contribution to journalReview article

166 Scopus citations

High-resolution mapping of genotype-phenotype relationships in cri du chat syndrome using array comparative genomic hybridization

Zhang, X., Snijders, A., Segraves, R., Zhang, X., Niebuhr, A., Albertson, D., Yang, H., Gray, J., Niebuhr, E., Bolund, L. & Pinkel, D., Feb 2005, In : American Journal of Human Genetics. 76, 2, p. 312-326 15 p.

Research output: Contribution to journalArticle

115 Scopus citations

Identification of a novel homozygous deletion region at 6q23.1 in medulloblastomas using high-resolution array: Comparative genomic hybridization analysis

Hui, A. B. Y., Takano, H., Lo, K. W., Kuo, W. L., Lam, C. N. Y., Tong, C. Y. K., Chang, Q., Gray, J. W. & Ng, H. K., Jul 1 2005, In : Clinical Cancer Research. 11, 13, p. 4707-4716 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Mapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGH

Kresse, S. H., Berner, J. M., Meza-Zepeda, L. A., Gregory, S. G., Kuo, W. L., Gray, J. W., Forus, A. & Myklebost, O., Nov 7 2005, In : Molecular Cancer. 4, 39.

Research output: Contribution to journalArticle

21 Scopus citations

Molecular characterization of the cytotoxic mechanism of multiwall carbon nanotubes and nano-onions on human skin fibroblast

Ding, L., Stilwell, J., Zhang, T., Elboudwarej, O., Jiang, H., Selegue, J. P., Cooke, P. A., Gray, J. W. & Chen, F. F., Dec 2005, In : Nano Letters. 5, 12, p. 2448-2464 17 p.

Research output: Contribution to journalArticle

418 Scopus citations

Nanoplasmonic biomolecular ruler with a 2 NM spatial resolution for probing restricted digestion of nucleic acids

Liu, G. L., Chen, F., Gerion, D., Yin, Y., Paul Alivisatos, A., Gray, J. W. & Lee, L. P., Jan 1 2005, Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Transducer Research Foundation, p. 1513-1515 3 p. (Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Quantum dots-based reverse phase protein microarray

Shingyoji, M., Gerion, D., Pinkel, D., Gray, J. W. & Chen, F., Sep 15 2005, In : Talanta. 67, 3, p. 472-478 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

Gupta, P. B., Kuperwasser, C., Brunet, J. P., Ramaswamy, S., Kuo, W. L., Gray, J. W., Naber, S. P. & Weinberg, R. A., Oct 2005, In : Nature genetics. 37, 10, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

329 Scopus citations

Translational crossroads for biomarkers

Bast, R. C., Lilja, H., Urban, N., Rimm, D. L., Fritsche, H., Gray, J., Veltri, R., Klee, G., Allen, A., Kim, N., Gutman, S., Rubin, M. A. & Hruszkewycz, A., Sep 1 2005, In : Clinical Cancer Research. 11, 17, p. 6103-6108 6 p.

Research output: Contribution to journalReview article

64 Scopus citations
2006

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

Neve, R. M., Chin, K., Fridlyand, J., Yeh, J., Baehner, F. L., Fevr, T., Clark, L., Bayani, N., Coppe, J. P., Tong, F., Speed, T., Spellman, P. T., DeVries, S., Lapuk, A., Wang, N. J., Kuo, W. L., Stilwell, J. L., Pinkel, D., Albertson, D. G., Waldman, F. M. & 7 others, McCormick, F., Dickson, R. B., Johnson, M. D., Lippman, M., Ethier, S., Gazdar, A. & Gray, J. W., Dec 2006, In : Cancer Cell. 10, 6, p. 515-527 13 p.

Research output: Contribution to journalArticle

2107 Scopus citations

A fluid membrane-based soluble ligand-display system for live-cell assays

Nam, J. M., Nair, P. M., Neve, R. M., Gray, J. W. & Groves, J. T., Mar 2006, In : ChemBioChem. 7, 3, p. 436-440 5 p.

Research output: Contribution to journalArticle

32 Scopus citations

A nanoplasmonic molecular ruler for measuring nuclease activity and dna footprinting

Liu, G. L., Yin, Y., Kunchakarra, S., Mukherjee, B., Gerion, D., Jett, S. D., Bear, D. G., Gray, J. W., Alivisatos, A. P., Lee, L. P. & Chen, F. F., Jan 2006, In : Nature nanotechnology. 1, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

262 Scopus citations

Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells

Lorenzi, P. L., Reinhold, W. C., Rudelius, M., Gunsior, M., Shankavaram, U., Bussey, K. J., Scherf, U., Eichler, G. S., Martin, S. E., Chin, K., Gray, J. W., Kohn, E. C., Horak, I. D., Von Hoff, D. D., Raffeld, M., Goldsmith, P. K., Caplen, N. J. & Weisntein, J. N., Nov 2006, In : Molecular cancer therapeutics. 5, 11, p. 2613-2623 11 p.

Research output: Contribution to journalArticle

69 Scopus citations

Breast tumor copy number aberration phenotypes and genomic instability

Fridlyand, J., Snijders, A. M., Ylstra, B., Li, H., Olshen, A., Segraves, R., Dairkee, S., Tokuyasu, T., Ljung, B. M., Jain, A. N., McLennan, J., Ziegler, J., Chin, K., Devries, S., Feiler, H., Gray, J. W., Waldman, F., Pinkel, D. & Albertson, D. G., Apr 18 2006, In : BMC cancer. 6, 96.

Research output: Contribution to journalArticle

228 Scopus citations

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

Rai, R., Dai, H., Multani, A. S., Li, K., Chin, K., Gray, J., Lahad, J. P., Liang, J., Mills, G. B., Meric-Bernstam, F. & Lin, S. Y., Aug 2006, In : Cancer Cell. 10, 2, p. 145-157 13 p.

Research output: Contribution to journalArticle

120 Scopus citations

Cellular effect of high doses of silica-coated quantum dot profiled with high throughput gene expression analysis and high content cellomics measurements

Zhang, T., Stilwell, J. L., Gerion, D., Ding, L., Elboudwarej, O., Cooke, P. A., Gray, J. W., Alivisatos, A. P. & Chen, F. F., Apr 2006, In : Nano Letters. 6, 4, p. 800-808 9 p.

Research output: Contribution to journalArticle

303 Scopus citations

Decoding the fine-scale structure of a breast cancer genome and transcriptome

Volik, S., Raphael, B. J., Huang, G., Stratton, M. R., Bignel, G., Murnane, J., Brebner, J. H., Bajsarowicz, K., Paris, P. L., Tao, Q., Kowbel, D., Lapuk, A., Shagin, D. A., Shagina, I. A., Gray, J. W., Cheng, J. F., De Jong, P. J., Pevzner, P. & Collins, C., Mar 2006, In : Genome Research. 16, 3, p. 394-404 11 p.

Research output: Contribution to journalArticle

49 Scopus citations