• 68549 Citations
  • 113 h-Index
1971 …2020

Research output per year

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Research Output

1996

Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer

Tanner, M. M., Tirkkonen, M., Kallioniemi, A., Isola, J., Kuukasjärvi, T., Collins, C., Kowbel, D., Guan, X. Y., Trent, J., Gray, J. W., Meltzer, P. & Kallioniemi, O. P., Aug 1 1996, In : Cancer Research. 56, 15, p. 3441-3445 5 p.

Research output: Contribution to journalArticle

176 Scopus citations

The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model.

Donehower, L. A., Godley, L. A., Aldaz, C. M., Pyle, R., Shi, Y. P., Pinkel, D., Gray, J., Bradley, A., Medina, D. & Varmus, H. E., 1996, In : Progress in clinical and biological research. 395, p. 1-11 11 p.

Research output: Contribution to journalReview article

21 Scopus citations
1997

20q gain associates with immortalization: 20q13.2 amplification correlates with genome instability in human papillomavirus 16 E7 transformed human uroepithelial cells

Savelieva, E., Belair, C. D., Newton, M. A., DeVries, S., Gray, J. W., Waldman, F. & Reznikoff, C. A., Jan 1 1997, In : Oncogene. 14, 5, p. 551-560 10 p.

Research output: Contribution to journalArticle

Open Access
118 Scopus citations

A t-statistic for objective interpretation of comparative genomic hybridization (CGH) profiles

Moore, D. H., Pallavicini, M., Cher, M. L. & Gray, J. W., Jul 1 1997, In : Cytometry. 28, 3, p. 183-190 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

DNA copy number changes associated with characteristic LOH in islet cell carcinomas of transgenic mice

Shi, Y. P., Naik, P., Dietrich, W. F., Gray, J. W., Hanahan, D. & Pinkel, D., Jun 14 1997, In : Genes Chromosomes and Cancer. 19, 2, p. 104-111 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

ESX: A structurally unique Ets overexpressed early during human breast tumorigenesis

Chang, C. H., Scott, G. K., Kuo, W. L., Xiong, X., Suzdaltseva, Y., Park, J. W., Sayre, P., Erny, K., Collins, C., Gray, J. W. & Benz, C. C., Jan 1 1997, In : Oncogene. 14, 13, p. 1617-1622 6 p.

Research output: Contribution to journalArticle

Open Access
151 Scopus citations

Evidence of a dominant transcriptional pathway which regulates an undifferentiated and complete metastatic phenotype

Barsky, S. H., Sternlicht, M. D., Safarians, S., Nguyen, M., Chin, K., Stewart, S. D., Hiti, A. L. & Gray, J. W., Jan 1 1997, In : Oncogene. 15, 17, p. 2077-2091 15 p.

Research output: Contribution to journalArticle

16 Scopus citations

FISH probes for mouse chromosome identification

Shi, Y. P., Mohapatra, G., Miller, J., Hanahan, D., Lander, E., Gold, P., Pinkel, D. & Gray, J., Oct 1 1997, In : Genomics. 45, 1, p. 42-47 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Objective aneuploidy detection for fetal and neonatal screening using comparative genomic hybridization (CGH)

Yu, L. C., Moore, D. H., Magrane, G., Cronin, J., Pinkel, D., Lebo, R. V. & Gray, J. W., Jul 1 1997, In : Cytometry. 28, 3, p. 191-197 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Subregional localization of 21 chromosome 7-specific expressed sequence tags (ESTs) by FISH using newly identified YACs and P1s

Morton, S. M., Veile, R. A., Helms, C., Lee, M., Kuo, W. L., Gray, J. & Donis-Keller, H., Dec 15 1997, In : Genomics. 46, 3, p. 491-494 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
1998

Cancer-associated gene abnormalities and chemosensitivity

Sakamoto, M., Umayahara, K., Sakamoto, H., Kawasaki, K., Suehiro, Y., Kunugi, T., Akiya, T., Iwabuchi, H., Sakunaga, H., Muroya, T., Kikuchi, Y., Sugishita, T., Tenjin, Y., Gray, J. W. & Tanaka, T., Oct 1998, In : Gan to kagaku ryoho. Cancer & chemotherapy. 25, 12, p. 1819-1831 13 p.

Research output: Contribution to journalReview article

4 Scopus citations

Efficient, interactive, and three-dimensional segmentation of cell nuclei in thick tissue sections

Lockett, S. J., Sudar, D., Thompson, C. T., Pinkel, D. & Gray, J. W., Apr 1 1998, In : Cytometry. 31, 4, p. 275-286 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

Genetic analysis using genomic representations

Lucito, R., Nakimura, M., West, J. A., Han, Y., Chin, K., Jensen, K., Mccombie, R., Gray, J. W. & Wigler, M., Apr 14 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 8, p. 4487-4492 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays

Pinkel, D., Segraves, R., Sudar, D., Clark, S., Poole, I., Kowbel, D., Collins, C., Kuo, W. L., Chen, C., Zhai, Y., Dairkee, S. H., Ljung, B. M., Gray, J. W. & Albertson, D. G., Oct 15 1998, In : Nature genetics. 20, 2, p. 207-211 5 p.

Research output: Contribution to journalArticle

1720 Scopus citations

Interactive system for registering adjacent tissue sections

Lockett, S. J., Fernandez, C., Rodriguez, E., Wesselmann, U., Bastian, B. C., Sudar, D., Pinkel, D. & Gray, J., Dec 1 1998, In : Proceedings of SPIE - The International Society for Optical Engineering. 3260, p. 154-161 8 p.

Research output: Contribution to journalConference article

Mechanisms of inactivation of E-cadherin in breast cancer cell lines

Hiraguri, S., Godfrey, T., Nakamura, H., Graff, J., Collins, C., Shayesteh, L., Doggett, N., Johnson, K., Wheelock, M., Herman, J., Baylin, S., Pinkel, D. & Gray, J., May 1 1998, In : Cancer Research. 58, 9, p. 1972-1977 6 p.

Research output: Contribution to journalArticle

119 Scopus citations

Molecular cytogenetic analysis of consistent abnormalities at 8q12-q22 in breast cancer

Fejzo, M. S., Godfrey, T., Chen, C., Waldman, F. & Gray, J. W., Jun 1 1998, In : Genes Chromosomes and Cancer. 22, 2, p. 105-113 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Positional cloning of ZNF217 and NABC1: Genes amplified at 20q13.2 and overexpressed in breast carcinoma

Collins, C., Rommens, J. M., Kowbel, D., Godfrey, T., Tanner, M., Hwang, S. I., Polikoff, D., Nonet, G., Cochran, J., Myambo, K., Jay, K. E., Froula, J., Cloutier, T., Kuo, W. L., Yaswen, P., Dairkee, S., Giovanola, J., Hutchinson, G. B., Isola, J., Kallioniemi, O. P. & 7 others, Palazzolo, M., Martin, C., Ericsson, C., Pinkel, D., Albertson, D., Li, W. B. & Gray, J. W., Jul 21 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 15, p. 8703-8708 6 p.

Research output: Contribution to journalArticle

262 Scopus citations

Segmentation of Cell Nuclei from Confocal Microscope Images of Thick Tissue Samples

Ortiz de Solorzano, C., Sarti, A., Rodriguez, E. G., Jones, A., Sudar, D., Pinkel, D., Gray, J. W., Malladi, R. & Lockett, S. J., Dec 1 1998, p. 187-190. 4 p.

Research output: Contribution to conferencePaper

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

Zhou, H., Kuang, J., Zhong, L., Kuo, W. L., Gray, J. W., Sahin, A., Brinkley, B. R. & Sen, S., Oct 15 1998, In : Nature genetics. 20, 2, p. 189-193 5 p.

Research output: Contribution to journalArticle

1086 Scopus citations
1999

Chromosome arm 20q gains and other genomic alterations in colorectal cancer metastatic to liver, as analyzed by comparative genomic hybridization and fluorescence in situ hybridization

Korn, W. M., Yasutake, T., Kuo, W. L., Warren, R. S., Collins, C., Tomita, M., Gray, J. & Waldman, F. M., Jun 1999, In : Genes Chromosomes and Cancer. 25, 2, p. 82-90 9 p.

Research output: Contribution to journalArticle

117 Scopus citations

Measurement of genetic instability in breast cancer by confocal microscopy and 3D image analysis

Ortiz de Solorzano, C., Chin, K., Chou, W. S., Knowles, D., Gray, J. W. & Lockett, S. J., Dec 1 1999, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. IEEE, 1 p. (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas

Yu, Y., Xu, F., Peng, H., Fang, X., Zhao, S., Li, Y., Cuevas, B., Kuo, W. L., Gray, J. W., Siciliano, M., Mills, G. B. & Bast, R. C., Jan 5 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 1, p. 214-219 6 p.

Research output: Contribution to journalArticle

253 Scopus citations

PlK3CA is implicated as an oncogene in ovarian cancer

Shayesteh, L., Lu, Y., Kuo, W. L., Baldocchi, R., Godfrey, T., Collins, C., Pinkel, D., Powell, B., Mills, G. B. & Gray, J. W., Jan 1 1999, In : Nature genetics. 21, 1, p. 99-102 4 p.

Research output: Contribution to journalArticle

980 Scopus citations

Segmentation of confocal microscope images of cell nuclei in thick tissue sections

Ortiz De Solórzano, C., García Rodriguez, E., Jones, A., Pinkel, D., Gray, J. W., Sudar, D. & Lockett, S. J., 1999, In : Journal of Microscopy. 193, 3, p. 212-226 15 p.

Research output: Contribution to journalArticle

125 Scopus citations

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

Sternlicht, M. D., Lochtest, A., Sympson, C. J., Huey, B., Rougier, J. P., Gray, J. W., Pinkel, D., Bissell, M. J. & Werb, Z., Jul 23 1999, In : Cell. 98, 2, p. 137-146 10 p.

Research output: Contribution to journalArticle

715 Scopus citations
2000

An approach to analysis of large-scale correlations between genome changes and clinical endpoints in ovarian cancer

Suzuki, S., Moore, D. H., Ginzinger, D. G., Godfrey, T. E., Barclay, J., Powell, B., Pinkel, D., Zaloudek, C., Lu, K., Mills, G., Berchuck, A. & Gray, J. W., Oct 1 2000, In : Cancer Research. 60, 19, p. 5382-5385 4 p.

Research output: Contribution to journalArticle

101 Scopus citations

ARHI is the center of allelic deletion on chromosome 1p31 in ovarian and breast cancers

Peng, H., Xu, F., Pershad, R., Hunt, K. K., Frazier, M. L., Berchuck, A., Gray, J. W., Hogg, D., Bast, R. C. & Yu, Y., 2000, In : International Journal of Cancer. 86, 5, p. 690-694 5 p.

Research output: Contribution to journalArticle

53 Scopus citations

Genome changes and gene expression in human solid tumors

Gray, J. W. & Collins, C., Jan 1 2000, In : Carcinogenesis. 21, 3, p. 443-452 10 p.

Research output: Contribution to journalReview article

Open Access
166 Scopus citations

HYAL1(LUCA-1), a candidate tumor suppressor gene on chromosome 3p21.3, is inactivated in head and neck squamous cell carcinomas by aberrant splicing of pre-mRNA

Frost, G. I., Mohapatra, G., Wong, T. M., Csóka, A. B., Gray, J. W. & Stern, R., Feb 17 2000, In : Oncogene. 19, 7, p. 870-877 8 p.

Research output: Contribution to journalArticle

Open Access
70 Scopus citations

In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002)

Hu, L., Zaloudek, C., Mills, G. B., Gray, J. & Jaffe, R. B., Mar 2000, In : Clinical Cancer Research. 6, 3, p. 880-886 7 p.

Research output: Contribution to journalArticle

270 Scopus citations

Measurement of DNA copy number at microsatellite loci using quantitative PCR analysis

Ginzinger, D. G., Godfrey, T. E., Nigro, J., Moore, D. H., Suzuki, S., Pallavicini, M. G., Gray, J. W. & Jensen, R. H., Oct 1 2000, In : Cancer Research. 60, 19, p. 5405-5409 5 p.

Research output: Contribution to journalArticle

135 Scopus citations

Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene

Albertson, D. G., Ylstra, B., Segraves, R., Collins, C., Dairkee, S. H., Kowbel, D., Kuo, W. L., Gray, J. W. & Pinkel, D., Jun 1 2000, In : Nature genetics. 25, 2, p. 144-146 3 p.

Research output: Contribution to journalArticle

494 Scopus citations

Quantitative mRNA expression analysis from formalin-fixed, paraffin-embedded tissues using 5′ nuclease quantitative reverse transcription-polymerase chain reaction

Godfrey, T. E., Kim, S. H., Chavira, M., Ruff, D. W., Warren, R. S., Gray, J. W. & Jensen, R. H., May 2000, In : Journal of Molecular Diagnostics. 2, 2, p. 84-91 8 p.

Research output: Contribution to journalArticle

255 Scopus citations
2001

A 20q13.2 cancer amplicon: Novel sequence analysis tools

Volik, S., Gray, J., Kowbel, D. & Collins, C., 2001, In : Nature Genetics. 27, 4S, p. 94 1 p.

Research output: Contribution to journalArticle

Assembly of microarrays for genome-wide measurement of DNA copy number

Snijders, A. M., Nowak, N., Segraves, R., Blackwood, S., Brown, N., Conroy, J., Hamilton, G., Hindle, A. K., Huey, B., Kimura, K., Law, S., Myambo, K., Palmer, J., Ylstra, B., Yue, J. P., Gray, J. W., Jain, A. N., Pinkel, D. & Albertson, D. G., Dec 10 2001, In : Nature genetics. 29, 3, p. 263-264 2 p.

Research output: Contribution to journalArticle

745 Scopus citations

Comparative genomic hybridization.

DeVries, S., Gray, J. W., Pinkel, D., Waldman, F. M. & Sudar, D., May 2001, In : Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.]. Chapter 4, p. Unit4.6

Research output: Contribution to journalArticle

2 Scopus citations

Comprehensive genome sequence analysis of a breast cancer amplicon

Collins, C., Volik, S., Kowbel, D., Ginzinger, D., Ylstra, B., Cloutier, T., Hawkins, T., Predki, P., Martin, C., Wernick, M., Kuo, W. L., Alberts, A. & Gray, J. W., 2001, In : Genome Research. 11, 6, p. 1034-1042 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

Comprehensive sequence analysis of a human 20q13.2 cancer amplicon

Collins, C., Volik, S., Kowbel, D., Wernick, M., Hawkins, T., Predki, P., Kuo, W. L. & Gray, J., 2001, In : Nature Genetics. 27, 4S, p. 48 1 p.

Research output: Contribution to journalArticle

Erratum: Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas (Journal of Vascular Technology (2001) 29 (459-464))

Hodgson, G., Hager, J. H., Volik, S., Hariono, S., Wernick, M., Moore, D., Nowak, N., Albertson, D. G., Pinkel, D., Collins, C., Hanahan, D. & Gray, J. W., Jan 1 2001, In : Nature genetics. 29, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
6 Scopus citations

Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas

Hodgson, G., Hager, J. H., Volik, S., Hariono, S., Wernick, M., Moore, D., Albertson, D. G., Pinkel, D., Collins, C., Hanahan, D. & Gray, J. W., 2001, In : Nature genetics. 29, 4, p. 459-464 6 p.

Research output: Contribution to journalArticle

250 Scopus citations

Genomics of islet cell carcinogenesis

Hager, J., Hodgson, G., Collins, C., Tsai, F. Y., Huszar, D., Gray, J. & Hanahan, D., Apr 2001, In : Nature genetics. 27, 4S, p. 57-58 2 p.

Research output: Contribution to journalArticle

Integration of cytogenetic landmarks into the draft sequence of the human genome

Cheung, V. G., Nowak, N., Jang, W., Kirsch, I. R., Zhao, S., Chen, X. N., Furey, T. S., Kim, U. J., Kuo, W. L., Olvier, M., Conroy, J., Kasprzyk, A., Massa, H., Yonescu, R., Sait, S., Thoreen, C., Snijders, A., Lemyre, E., Bailey, J. A., Bruzel, A. & 40 others, Burrill, W. D., Clegg, S. M., Collins, S., Dhami, P., Friedman, C., Han, C. S., Herrick, S., Lee, J., Ligon, A. H., Lowry, S., Moriey, M., Narasimhan, S., Osoegawa, K., Peng, Z., Plajzer-Frick, I., Quade, B. J., Scott, D., Sirotkin, K., Thorpe, A. A., Gray, J. W., Hudson, J., Pinkel, D., Ried, T., Rowen, L., Shen-Ong, G. L., Strausberg, R. L., Birney, E., Callen, D. F., Cheng, J. F., Cox, D. R., Doggett, N. A., Carter, N. P., Eichler, E. E., Haussler, D., Korenberg, J. R., Morton, C. C., Albertson, D., Schuler, G., De Jong, P. J. & Trask, B. J., Feb 15 2001, In : Nature. 409, 6822, p. 953-958 6 p.

Research output: Contribution to journalLetter

238 Scopus citations

Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival

Jain, A. N., Chin, K., Børresen-Dale, A. L., Erikstein, B. K., Lonning, P. E., Kaaresen, R. & Gray, J. W., 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 14, p. 7952-7957 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

Response to neoadjuvant therapy for breast cancer by magnetic resonance imaging type, estrogen receptor status, grade, and comparative genomic hybridization

Esserman, L. J., Sudilovsky, D., Kuo, W. I., Gray, J. & Hylton, N., Dec 1 2001, In : Breast Cancer Research and Treatment. 69, 3, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Stromal-epithelial interactions in the progression of ovarian cancer: Influence and source of tumor stromal cells

Parrott, J. A., Nilsson, E., Mosher, R., Magrane, G., Albertson, D., Pinkel, D., Gray, J. W. & Skinner, M. K., Apr 25 2001, In : Molecular and Cellular Endocrinology. 175, 1-2, p. 29-39 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy

Mills, G. B., Lu, Y., Fang, X., Wang, H., Eder, A., Mao, M., Swaby, R., Cheng, K. W., Stokoe, D., Siminovitch, K., Jaffe, R. & Gray, J., 2001, In : Seminars in Oncology. 28, 5 SUPPL. 16, p. 125-141 17 p.

Research output: Contribution to journalArticle

112 Scopus citations

The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells

Nonet, G. H., Stampfer, M. R., Chin, K., Gray, J. W., Collins, C. C. & Yaswen, P., Feb 15 2001, In : Cancer Research. 61, 4, p. 1250-1254 5 p.

Research output: Contribution to journalArticle

121 Scopus citations
2002

Biallelic inactivation of the thyroid hormone receptor β1 gene in early stage breast cancer

Li, Z., Meng, Z. H., Chandrasekaran, R., Kuo, W. L., Collins, C. C., Gray, J. W. & Dairkee, S. H., Apr 1 2002, In : Cancer Research. 62, 7, p. 1939-1943 5 p.

Research output: Contribution to journalArticle

75 Scopus citations

Gene encoding protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

Anand, N., Murthy, S., Amann, G., Wernick, M., Porter, L. A., Cukier, I. H., Collins, C., Gray, J. W., Diebold, J., Demetrick, D. J. & Lee, J. M., Jul 2002, In : Nature genetics. 31, 3, p. 301-305 5 p.

Research output: Contribution to journalArticle

194 Scopus citations