• 65500 Citations
  • 111 h-Index
1971 …2020
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Research Output 1971 2020

1992
14 Citations (Scopus)

Construction and characterization of a yeast artificial chromosome library containing 1.5 equivalents of human chromosome 21

Potier, M. C., Kuo, W. L., Dutriaux, A., Gray, J. & Goedert, M., 1992, In : Genomics. 14, 2, p. 481-483 3 p.

Research output: Contribution to journalArticle

Yeast Artificial Chromosomes
Chromosomes, Human, Pair 21
Human Chromosomes
Yeasts
Libraries
107 Citations (Scopus)

Deletion of chromosome 17p loci in breast cancer cells detected by fluorescence in situ hybridization

Matsumura, K., Kallioniemi, A., Kallioniemi, O., Chen, L., Smith, H. S., Pinkel, D., Gray, J. & Waldman, F. M., Jun 15 1992, In : Cancer Research. 52, 12, p. 3474-3477 4 p.

Research output: Contribution to journalArticle

Chromosome Deletion
Loss of Heterozygosity
Fluorescence In Situ Hybridization
Breast Neoplasms
Centromere
45 Citations (Scopus)

Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization

Kallioniemi, A., Kallioniemi, O. P., Waidman, F. M., Chen, L. C., Yu, L. C., Fung, Y. K. T., Smith, H. S., Pinkel, D. & Gray, J., 1992, In : Cytogenetic and Genome Research. 60, 3-4, p. 190-193 4 p.

Research output: Contribution to journalArticle

Retinoblastoma Genes
Gene Dosage
Interphase
Metaphase
Fluorescence In Situ Hybridization
5 Citations (Scopus)

Differential staining of human and murine chromatin in situ by hybridization with species-specific satellite DNA probes

Weier, H. U. G., Zitzelsberger, H. F. & Gray, J., Feb 14 1992, In : Biochemical and Biophysical Research Communications. 182, 3, p. 1313-1319 7 p.

Research output: Contribution to journalArticle

Satellite DNA
DNA Probes
Chromatin
In Situ Hybridization
Chromosomes
435 Citations (Scopus)

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization

Kallioniemi, O. P., Kallioniemi, A., Kurisu, W., Thor, A., Chen, L. C., Smith, H. S., Waldman, F. M., Pinkel, D. & Gray, J., 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 12, p. 5321-5325 5 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Breast Neoplasms
Cell Line
Neoplasms
Chromosomes, Human, Pair 17
19 Citations (Scopus)

Factors that determine the in vivo dose-response relationship for stable chromosome aberrations in A-bomb survivors.

Awa, A. A., Nakano, M., Ohtaki, K., Kodama, Y., Lucas, J. & Gray, J., Mar 1992, In : Journal of Radiation Research. 33 Suppl, p. 206-214 9 p.

Research output: Contribution to journalArticle

Bombs
chromosome aberrations
Chromosome Aberrations
dose response
Survivors
21 Citations (Scopus)

Molecular cytogenetics: Diagnosis and prognostic assessment

Gray, J., Kallioniemi, A., Kallioniemi, O., Pallavicini, M., Waldman, F. & Pinkel, D., 1992, In : Current Opinion in Biotechnology. 3, 6, p. 623-631 9 p.

Research output: Contribution to journalArticle

Cytogenetics
Primed In Situ Labeling
Comparative Genomic Hybridization
Cytogenetic Analysis
Chromosomes
66 Citations (Scopus)

Molecular cytogenetics in human cancer diagnosis

Gray, J. & Pinkel, D., 1992, In : Cancer. 69, 6 SUPPL., p. 1536-1542 7 p.

Research output: Contribution to journalArticle

Cytogenetics
Chromosomes
Centromere
Gene Amplification
Interphase
131 Citations (Scopus)

Radiation-induced chromosome aberrations analysed by fluorescence in situ hybridization with a triple combination of composite whole chromosome-specific DNA probes

Schmid, E., Zitzelsberger, H., Braselmann, H., Gray, J. & Bauchinger, M., 1992, In : International Journal of Radiation Biology. 62, 6, p. 673-678 6 p.

Research output: Contribution to journalArticle

chromosome aberrations
chromosomes
DNA probes
DNA Probes
Chromosomes
422 Citations (Scopus)

Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation

Lucas, J. N., Awa, A., Straume, T., Poggensee, M., Kodama, Y., Nakano, M., Ohtaki, K., Weier, H. U., Pinkel, D., Gray, J. & Littlefield, G., 1992, In : International Journal of Radiation Biology. 62, 1, p. 53-63 11 p.

Research output: Contribution to journalArticle

Ionizing radiation
Ionizing Radiation
ionizing radiation
Fluorescence In Situ Hybridization
Fluorescence
23 Citations (Scopus)

Structural chromosome analysis by whole chromosome painting for assessment of radiation-induced genetic damage.

Gray, J., Lucas, J. N., Pinkel, D. & Awa, A., Mar 1992, In : Journal of Radiation Research. 33 Suppl, p. 80-86 7 p.

Research output: Contribution to journalArticle

Radiation Genetics
Chromosome Painting
Nucleic Acid Hybridization
chromosome aberrations
chromosomes
128 Citations (Scopus)

X-ray laser microscopy of rat sperm nuclei

Da Silva, L. B., Trebes, J. E., Balhorn, R., Mrowka, S., Anderson, E., Attwood, D. T., Barbee, T. W., Brase, J., Corzett, M., Gray, J., Koch, J. A., Lee, C., Kern, D., London, R. A., MacGowan, B. J., Matthews, D. L. & Stone, G., Oct 9 1992, In : Science. 258, 5080, p. 269-271 3 p.

Research output: Contribution to journalArticle

Confocal Microscopy
Spermatozoa
X-Rays
Chromatin
Microscopy
1993
4 Citations (Scopus)

Application of confocal laser scanning microscope on fluorescence in situ hybridization (FISH)

Matsuta, M., Matsuta, M., Sasaki, K., Hariu, H., Nishiya, I., Katou, M., Kallioniemi, A., Weier, H. U. & Gray, J., 1993, In : Acta Histochemica et Cytochemica. 26, 5, p. 415-421 7 p.

Research output: Contribution to journalArticle

DNA sequences
Chromosomes
Fluorescence In Situ Hybridization
Chromosomes, Human, Pair 6
Lasers
7 Citations (Scopus)

Application of x rays to the analysis of DNA packaging in mammalian sperm

Balhorn, R., Corzett, M., Allen, M. J., Lee, C., Barbee, T. W., Koch, J. A., MacGowan, B. J., Matthews, D. L., Mrowka, S. J., Trebes, J. E., McNulty, I., Da Silva, L. B., Gray, J., Anderson, E. H., Kern, D. & Attwood, D. T., 1993, Proceedings of SPIE - The International Society for Optical Engineering. Publ by Int Soc for Optical Engineering, Vol. 1741. p. 374-385 12 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

packaging
Packaging
DNA
deoxyribonucleic acid
X rays
12 Citations (Scopus)

Chromosomal Reassignment: YACs Containing Both YES1 and Thymidylate Synthase Map to the Short Arm of Chromosome 18

Silverman, G. A., Kuo, W. L., Taillon-Miller, P. & Gray, J., Feb 1993, In : Genomics. 15, 2, p. 442-445 4 p.

Research output: Contribution to journalArticle

Yeast Artificial Chromosomes
Chromosomes, Human, Pair 18
Thymidylate Synthase
Genes
Proto-Oncogenes
6 Citations (Scopus)

Cloning and Characterization of EagI YACs from Human Chromosome 21

Gingrich, J. C., Lowry, S. R., Kuo, W. L., Gray, J., Smith, C. L. & Cantori, C. R., Jan 1993, In : Genomics. 15, 1, p. 228-230 3 p.

Research output: Contribution to journalArticle

Yeast Artificial Chromosomes
Chromosomes, Human, Pair 21
Human Chromosomes
Organism Cloning
Hybrid Cells
202 Citations (Scopus)

Comparative genomic hybridization: A rapid new method for detecting and mapping DNA amplification in tumors

Kallioniemi, O. P., Kallioniemi, A., Sudar, D., Rutovitz, D., Gray, J., Waldman, F. & Pinkel, D., 1993, In : Seminars in Cancer Biology. 4, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

Comparative Genomic Hybridization
DNA
Neoplasms
Metaphase
Fluorescent Dyes
20 Citations (Scopus)
Comparative Genomic Hybridization
Fluorescence In Situ Hybridization
Cytogenetics
Neoplasms
Chromosomes
3 Citations (Scopus)

Derivative domain fitting: A new method for resolving a mixture of normal distributions in the presence of a contaminating background

Moore, D. H. & Gray, J., 1993, In : Cytometry. 14, 5, p. 510-518 9 p.

Research output: Contribution to journalArticle

Normal Distribution
Least-Squares Analysis
18 Citations (Scopus)
Satellite DNA
Chromosomes, Human, Pair 10
DNA Primers
Cell Separation
Interphase

Imaging microscopy with x-ray lasers at LLNL

Da Silva, L. B., Trebes, J. E., Mrowka, S. J., MacGowan, B. J., Koch, J. A., Matthews, D. L., Barbee, T. W., Balhorn, R., Gray, J., Anderson, E. H., Kern, D. & Attwood, D. T., 1993, Proceedings of SPIE - The International Society for Optical Engineering. Publ by Int Soc for Optical Engineering, Vol. 1741. p. 154-159 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

x ray lasers
Microscopic examination
microscopy
Imaging techniques
X rays
59 Citations (Scopus)

Libraries for each human chromosome, constructed from sorter-enriched chromosomes by using linker-adaptor PCR

Vooijs, M., Yu, L. C., Tkachuk, D., Pinkel, D., Johnson, D. & Gray, J., Mar 1993, In : American Journal of Human Genetics. 52, 3, p. 586-597 12 p.

Research output: Contribution to journalArticle

Human Chromosomes
Libraries
Chromosomes
Polymerase Chain Reaction
Oligonucleotides
4 Citations (Scopus)

Molecular cytogenetic analysis of human tumors

Gray, J., 1993, In : Annals of the New York Academy of Sciences. 677, p. 194-198 5 p.

Research output: Contribution to journalArticle

Flow cytometry
Cytogenetic Analysis
Fluorescence microscopy
Tumor Suppressor Genes
Oncogenes
4 Citations (Scopus)

Molecular cytogenetics: Solid tumors and leukemia

Gray, J. & Pallavicini, M. G., 1993, In : Blood Cells. 19, 3, p. 677-683 7 p.

Research output: Contribution to journalArticle

Cytogenetics
Leukemia
Molecular Evolution
Neoplasms
Inborn Genetic Diseases
1994
21 Citations (Scopus)

A mouse Chromosome 11 library generated from sorted chromosomes using linker-adapter polymerase chain reaction

Miyashita, K., Vooijs, M. A., Tucker, J. D., Lee, D. A., Gray, J. & Pallavicini, M. G., 1994, In : Cytogenetic and Genome Research. 66, 1, p. 54-57 4 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 11
Chromosomes
Polymerase Chain Reaction
DNA
Metaphase
4 Citations (Scopus)

Defining the steps in a multistep mouse model for mammary carcinogenesis

Varmus, H. E., Godley, L. A., Roy, S., Taylor, I. C. A., Yuschenkoff, L., Shi -, Y. P., Pinkel, D., Gray, J., Pyle, R., Aldaz, C. M., Bradley, A., Medina, D. & Donehower, L. A., 1994, In : Cold Spring Harbor Symposia on Quantitative Biology. 59, p. 491-499 9 p.

Research output: Contribution to journalArticle

carcinogenesis
breasts
Tumors
Carcinogenesis
Breast
674 Citations (Scopus)

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

Kallioniemi, A., Kallioniemi, O. P., Piper, J., Tanner, M., Stokke, T., Chen, L., Smith, H. S., Pinkel, D., Gray, J. & Waldman, F. M., Mar 15 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 6, p. 2156-2160 5 p.

Research output: Contribution to journalArticle

Comparative Genomic Hybridization
Breast Neoplasms
Genes
Cell Line
Neoplasms
2 Citations (Scopus)

Detection of a human chromosomal translocation t(8;9) in a baby with multiple malformations using two-color fluorescence in situ hybridization

Sasaki, K., Pinkel, D., Tsukahara, M., Murano, I. & Gray, J., 1994, In : Pathology International. 44, 2, p. 145-150 6 p.

Research output: Contribution to journalArticle

Genetic Translocation
Fluorescence In Situ Hybridization
Chromosomes, Human, Pair 8
Chromosomes, Human, Pair 9
Color
1 Citation (Scopus)

Digital imaging microscopy for molecular cytogenetics

Gray, J., Lockett, S., Mascio, L., Mullikin, J., Pinkel, D., Piper, J., Sudar, D. & Thompson, C., 1994, Proceedings - Annual Meeting, Microscopy Society of America. Bailey, G. W. & Garratt-Reed, A. J. (eds.). p. 82-83 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Histology
Image acquisition
Microscopic examination
Genes
Display devices
56 Citations (Scopus)

Fluorescence in situ hybridization in cancer and radiation biology

Gray, J., Pinkel, D. & Brown, J. M., 1994, In : Radiation Research. 137, 3, p. 275-289 15 p.

Research output: Contribution to journalArticle

Primed In Situ Labeling
Radiobiology
comparative genomic hybridization
Comparative Genomic Hybridization
application technology
55 Citations (Scopus)

Generation of Five High-Complexity Painting Probe Libraries from Flow-Sorted Mouse Chromosomes

Weier, H. U. G., Polikoff, D., Fawcett, J. J., Greulich, K. M., Lee, K. H., Cram, S., Chapman, V. M. & Gray, J., Jun 1994, In : Genomics. 21, 3, p. 641-644 4 p.

Research output: Contribution to journalArticle

Paintings
Chromosomes
DNA
Metaphase
Polymerase Chain Reaction
80 Citations (Scopus)

Identification of frequent novel genetic alterations in small cell lung carcinoma

Levin, N. A., Brzoska, P., Gupta, N., Gray, J., Gray, J. W. & Christman, M. F., Oct 1 1994, In : Cancer Research. 54, 19, p. 5086-5091 6 p.

Research output: Contribution to journalArticle

DNA Copy Number Variations
Small Cell Lung Carcinoma
Phenotype
Comparative Genomic Hybridization
DNA
163 Citations (Scopus)

Increased copy number at 20q13 in breast cancer: Defining the critical region and exclusion of candidate genes

Tanner, M. M., Tirkkonen, M., Kallioniemi, A., Collins, C., Stokke, T., Karhu, R., Kowbel, D., Shadravan, F., Hintz, M., Kuo, W. L., Waldman, F. M., Isola, J. J., Gray, J. & Kallioniemi, O. P., Aug 15 1994, In : Cancer Research. 54, 16, p. 4257-4260 4 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Genes
Cosmids
Comparative Genomic Hybridization
Interphase
20 Citations (Scopus)

Interphase cytogenetics of melanocytic neoplasms: Numerical aberrations of chromosomes can be detected in interphase nuclei using centromeric DNA probes

Matsuta, M., Matsuta, M., Kon, S., Thompson, C., LeBoit, P. E., Weier, H. U. & Gray, J., 1994, In : Journal of Cutaneous Pathology. 21, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Interphase
DNA Probes
Epithelioid and Spindle Cell Nevus
Fluorescence In Situ Hybridization
Cytogenetics
7 Citations (Scopus)

Intracellular dynamics of c-myc mRNA traffic in single cells in situ

Pallavicini, M. G., George, T., Deteresa, P. S., Amendola, R. & Gray, J., Feb 1994, In : Journal of Cellular Physiology. 158, 2, p. 223-230 8 p.

Research output: Contribution to journalArticle

Chemical activation
Messenger RNA
Transcriptional Activation
Gene expression regulation
Cytoplasm
26 Citations (Scopus)

Molecular cytogenetics of human breast cancer

Gray, J., Collins, C., Henderson, I. C., Isola, J., Kallioniemi, A., Kallioniemi, O. P., Nakamura, H., Pinkel, D., Stokke, T., Tanner, M. & Waldman, F., 1994, In : Cold Spring Harbor Symposia on Quantitative Biology. 59, p. 645-652 8 p.

Research output: Contribution to journalArticle

Ports and harbors
cytogenetics
Cytogenetics
breast neoplasms
Genes
932 Citations (Scopus)

Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors

Kallioniemi, O. P., Kallioniemi, A., Piper, J., Isola, J., Waldman, F. M., Gray, J. & Pinkel, D., 1994, In : Genes Chromosomes and Cancer. 10, 4, p. 231-243 13 p.

Research output: Contribution to journalArticle

DNA Copy Number Variations
Comparative Genomic Hybridization
Neoplasms
Metaphase
DNA
32 Citations (Scopus)

Physical Mapping of Chromosome 17 Cosmids by Fluorescence in Situ Hybridization and Digital Image Analysis

Kallioniemi, O. P., Kallioniemi, A., Mascio, L., Sudar, D., Pinkel, D., Deaven, L. & Gray, J., Mar 1 1994, In : Genomics. 20, 1, p. 125-128 4 p.

Research output: Contribution to journalArticle

Cosmids
Chromosomes, Human, Pair 17
Fluorescence In Situ Hybridization
Metaphase
Hybrid Cells
128 Citations (Scopus)

Statement on Use of DNA Testing for Presymptomatic Identification of Cancer Risk

Collins, F. S., Benjamin, L. J., Botstein, D., Cox, J. R., Davidson, N., Gray, J., Housman, D. E., Holtzman, N., Jamison, K. R., Rothstein, R., Smith, D. C., Smith, L. M., Spence, M. A. & Tilghman, S. M., Mar 9 1994, In : JAMA - Journal of the American Medical Association. 271, 10, p. 785 1 p.

Research output: Contribution to journalArticle

Inborn Genetic Diseases
Genetic Testing
Advisory Committees
Oncogenes
DNA
61 Citations (Scopus)

Thick-section fluorescence in situ hybridization on formalin-fixed, paraffin-embedded archival tissue provides a histogenetic profile

Thompson, C. T., LeBoit, P. E., Nederlof, P. M. & Gray, J., Feb 1994, In : American Journal of Pathology. 144, 2, p. 237-243 7 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Paraffin
Formaldehyde
Gene Dosage
DNA Probes
1995
127 Citations (Scopus)

Amplification of chromosomal region 20q13 in invasive breast cancer: Prognostic implications

Tanner, M. M., Tirkkonen, M., Kallioniemi, A., Holli, K., Collins, C., Kowbel, D., Gray, J., Kallioniemi, O. P. & Isola, J., Dec 1995, In : Clinical Cancer Research. 1, 12, p. 1455-1461 7 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Fluorescence In Situ Hybridization
Neoplasm Metastasis
Neoplasms
Cosmids
57 Citations (Scopus)

A physical map of chromosome 20 established using fluorescence in situ hybridization and digital image analysis

Stokke, T., Collins, C., Kuo, W. L., Kowbel, D., Shadravan, F., Tanner, M., Kallioniemi, A., Kallioniemi, O. P., Pinkel, D., Deaven, L. & Gray, J., Mar 1 1995, In : Genomics. 26, 1, p. 134-137 4 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 20
Fluorescence In Situ Hybridization
Clone Cells
Cosmids
Libraries
28 Citations (Scopus)

Chromosomal localization of the γ-glutamyl carboxylase gene at 2p12

Kuo, W. L., Stafford, D. W., Cruces, J., Gray, J. & Jesú, S., Feb 10 1995, In : Genomics. 25, 3, p. 746-748 3 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 2
Genes
Hybrid Cells
Human Genome
Fluorescence In Situ Hybridization
235 Citations (Scopus)

Computer image analysis of comparative genomic hybridization

Piper, J., Rutovitz, D., Sudar, D., Kallioniemi, A., Kallioniemi, O. P., Waldman, F. M., Gray, J. & Pinkel, D., 1995, In : Cytometry. 19, 1, p. 10-26 17 p.

Research output: Contribution to journalArticle

Comparative Genomic Hybridization
Chromosomes
DNA
Metaphase
Fluorescent Dyes
243 Citations (Scopus)

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

Donehower, L. A., Godley, L. A., Aldaz, C. M., Pyle, R., Shi, Y. P., Pinkel, D., Gray, J., Bradley, A., Medina, D. & Varmus, H. E., 1995, In : Genes and Development. 9, 7, p. 882-895 14 p.

Research output: Contribution to journalArticle

Chromosomal Instability
Transgenic Mice
Carcinogenesis
Breast
Alleles
97 Citations (Scopus)

Frequent novel DNA copy number increase in squamous cell head and neck tumors

Brzoska, P. M., Levin, N. A., Fu, K. K., Kaplan, M. J., Singer, M. I., Gray, J. & Christman, M. F., 1995, In : Cancer Research. 55, 14, p. 3055-3059 5 p.

Research output: Contribution to journalArticle

DNA Copy Number Variations
Neck
Chromosomes
Epithelial Cells
Cultured Cells
274 Citations (Scopus)

Genetic analysis of benign, low-grade, and high-grade ovarian tumors

Iwabuchi, H., Sakamoto, M., Sakunaga, H., Ma, Y. Y., Carcangiu, M. L., Pinkel, D., Yang-Feng, T. L. & Gray, J., 1995, In : Cancer Research. 55, 24, p. 6172-6180 9 p.

Research output: Contribution to journalArticle

Neoplasms
Comparative Genomic Hybridization
Loss of Heterozygosity
Microsatellite Instability
Microsatellite Repeats
83 Citations (Scopus)

Identification of novel regions of altered DNA copy number in small cell lung tumors

Levin, N. A., Brzoska, P. M., Warnock, M. L., Gray, J. & Christman, M. F., 1995, In : Genes Chromosomes and Cancer. 13, 3, p. 175-185 11 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Lung
DNA
Neoplasms
Comparative Genomic Hybridization
2 Citations (Scopus)

Interactive algorithms for rapid enumeration of hybridization signals in individual whole-cell nuclei inside intact-tissue specimens

Lockett, S. J., Thompson, C. T., Mullikin, J. C., Sudar, D., Khavari, R., Hyun, W., Pinkel, D. & Gray, J., 1995, Proceedings of SPIE - The International Society for Optical Engineering. Wilson, T. & Cogswell, C. J. (eds.). Society of Photo-Optical Instrumentation Engineers, Vol. 2412. p. 43-49 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

enumeration
Fluorescence
Cells
Tissue
nuclei
20 Citations (Scopus)

Karyotypic heterogeneity and its relation to labeling index in interphase breast tumor cells

Balazs, M., Matsumura, K., Moore, D., Pinkel, D., Gray, J. & Waldman, F. M., 1995, In : Cytometry. 20, 1, p. 62-73 12 p.

Research output: Contribution to journalArticle

Interphase
Chromosomes
Breast Neoplasms
Bromodeoxyuridine
Chromosomes, Human, Pair 1