• 68128 Citations
  • 113 h-Index
1971 …2020

Research output per year

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Research Output

1992

Factors that Determine the in vivo Dose-Response Relationship for Stable Chromosome Aberrations in A-Bomb Survivors

Awa, A. A., Nakano, M., Ohtaki, K., Kodama, Y., Lucas, J. & Gray, J., Jan 1 1992, In : Journal of radiation research. 33, p. 206-214 9 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Molecular cytogenetics: Diagnosis and prognostic assessment

Gray, J. W., Kallioniemi, A., Kallioniemi, O., Pallavicini, M., Waldman, F. & Pinkel, D., Dec 1992, In : Current Opinion in Biotechnology. 3, 6, p. 623-631 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Molecular cytogenetics in human cancer diagnosis

Gray, J. W. & Pinkel, D., Mar 15 1992, In : Cancer. 69, 6 S, p. 1536-1542 7 p.

Research output: Contribution to journalArticle

67 Scopus citations

Radiation-induced chromosome aberrations analysed by fluorescence in situ hybridization with a triple combination of composite whole chromosome-specific DNA probes

Schmid, E., Zitzelsberger, H., Braselmann, H., Gray, J. W. & Bauchinger, M., Jan 1 1992, In : International Journal of Radiation Biology. 62, 6, p. 673-678 6 p.

Research output: Contribution to journalArticle

131 Scopus citations

Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation

Lucas, J. N., Awa, A., Straume, T., Poggensee, M., Kodama, Y., Nakano, M., Ohtaki, K., Weier, H. U., Pinkel, D., Gray, J. & Littlefield, G., Jan 1 1992, In : International Journal of Radiation Biology. 62, 1, p. 53-63 11 p.

Research output: Contribution to journalArticle

426 Scopus citations

Structural Chromosome Analysis by Whole Chromosome Painting for Assessment of Radiation-Induced Genetic Damage

Gray, J. W., Pinkel, D., Lucas, J. N. & Awa, A., Jan 1 1992, In : Journal of radiation research. 33, p. 80-86 7 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

X-ray laser microscopy of rat sperm nuclei

Da Silva, L. B., Trebes, J. E., Balhorn, R., Mrowka, S., Anderson, E., Attwood, D. T., Barbee, T. W., Brase, J., Corzett, M., Gray, J., Koch, J. A., Lee, C., Kern, D., London, R. A., MacGowan, B. J., Matthews, D. L. & Stone, G., Jan 1 1992, In : Science. 258, 5080, p. 269-271 3 p.

Research output: Contribution to journalArticle

128 Scopus citations
1993

Application of confocal laser scanning microscope on fluorescence in situ hybridization (FISH)

Matsuta, M., Matsuta, M., Sasaki, K., Hariu, H., Nishiya, I., Katou, M., Kallioniemi, A., Weier, H. U. & Gray, J. W., Jan 1 1993, In : Acta Histochemica et Cytochemica. 26, 5, p. 415-421 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Application of x rays to the analysis of DNA packaging in mammalian sperm

Balhorn, R., Corzett, M., Allen, M. J., Lee, C., Barbee, T. W., Koch, J. A., MacGowan, B. J., Matthews, D. L., Mrowka, S. J., Trebes, J. E., McNulty, I., Da Silva, L. B., Gray, J. W., Anderson, E. H., Kern, D. & Attwood, D. T., Jan 1 1993, Proceedings of SPIE - The International Society for Optical Engineering. Publ by Int Soc for Optical Engineering, p. 374-385 12 p. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 1741).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Chromosomal reassignment: Yacs containing both yes1 and thymidylate synthase map to the short arm of chromosome 18

Silverman, G. A., Kuo, W. L., Taillon-Miller, P. & Gray, J. W., Feb 1993, In : Genomics. 15, 2, p. 442-445 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cloning and Characterization of EagI YACs from Human Chromosome 21

Gingrich, J. C., Lowry, S. R., Kuo, W. L., Gray, J., Smith, C. L. & Cantori, C. R., Jan 1993, In : Genomics. 15, 1, p. 228-230 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Comparative genomic hybridization: A rapid new method for detecting and mapping DNA amplification in tumors

Kallioniemi, O. P., Kallioniemi, A., Sudar, D., Rutovitz, D., Gray, J. W., Waldman, F. & Pinkel, D., Dec 1 1993, In : Seminars in Cancer Biology. 4, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

203 Scopus citations

Cytogenetic profiling using fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH)

Thompson, C. T. & Gray, J. W., 1993, In : Journal of cellular biochemistry. 53, S17G, p. 139-143 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Derivative domain fitting: A new method for resolving a mixture of normal distributions in the presence of a contaminating background

Moore, D. H. & Gray, J. W., 1993, In : Cytometry. 14, 5, p. 510-518 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
18 Scopus citations

Imaging microscopy with x-ray lasers at LLNL

Da Silva, L. B., Trebes, J. E., Mrowka, S. J., MacGowan, B. J., Koch, J. A., Matthews, D. L., Barbee, T. W., Balhorn, R., Gray, J. W., Anderson, E. H., Kern, D. & Attwood, D. T., Jan 1 1993, Proceedings of SPIE - The International Society for Optical Engineering. Publ by Int Soc for Optical Engineering, p. 154-159 6 p. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 1741).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Libraries for each human chromosome, constructed from sorter-enriched chromosomes by using linker-adaptor PCR

Vooijs, M., Yu, L. C., Tkachuk, D., Pinkel, D., Johnson, D. & Gray, J. W., Jan 1 1993, In : American Journal of Human Genetics. 52, 3, p. 586-597 12 p.

Research output: Contribution to journalArticle

59 Scopus citations

Molecular Cytogenetic Analysis of Human Tumors

GRAY, JOE. W., Mar 1993, In : Annals of the New York Academy of Sciences. 677, 1, p. 194-198 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Molecular cytogenetics: Solid tumors and leukemia

Gray, J. W. & Pallavicini, M. G., Dec 1 1993, In : Blood Cells. 19, 3, p. 677-683 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
1994

A mouse Chromosome 11 library generated from sorted chromosomes using linker-adapter polymerase chain reaction

Miyashita, K., Vooijs, M. A., Tucker, J. D., Lee, D. A., Gray, J. W. & Pallavicini, M. G., Jan 1 1994, In : Cytogenetic and Genome Research. 66, 1, p. 54-57 4 p.

Research output: Contribution to journalArticle

21 Scopus citations

Defining the steps in a multistep mouse model for mammary carcinogenesis

Varmus, H. E., Godley, L. A., Roy, S., Taylor, I. C. A., Yuschenkoff, L., Shi -, Y. P., Pinkel, D., Gray, J., Pyle, R., Aldaz, C. M., Bradley, A., Medina, D. & Donehower, L. A., 1994, In : Cold Spring Harbor symposia on quantitative biology. 59, p. 491-499 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

Kallioniemi, A., Kallioniemi, O. P., Piper, J., Tanner, M., Stokke, T., Chen, L., Smith, H. S., Pinkel, D., Gray, J. W. & Waldman, F. M., Mar 15 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 6, p. 2156-2160 5 p.

Research output: Contribution to journalArticle

Open Access
678 Scopus citations

Detection of a human chromosomal translocation t(8;9) in a baby with multiple malformations using two‐color fluorescence in situ hybridization

Sasaki, K., Pinkel, D., Tsukahara, M., Murano, I. & Gray, J. W., Feb 1994, In : Pathology International. 44, 2, p. 145-150 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Digital imaging microscopy for molecular cytogenetics

Gray, J., Lockett, S., Mascio, L., Mullikin, J., Pinkel, D., Piper, J., Sudar, D. & Thompson, C., Dec 1 1994, p. 82-83. 2 p.

Research output: Contribution to conferencePaper

1 Scopus citations

Fluorescence in situ hybridization in cancer and radiation biology

Gray, J. W., Pinkel, D. & Brown, J. M., Jan 1 1994, In : Radiation research. 137, 3, p. 275-289 15 p.

Research output: Contribution to journalReview article

56 Scopus citations

Generation of five high-complexity painting probe libraries from flow-sorted mouse chromosomes

Weier, H. U. G., Polikoff, D., Fawcett, J. J., Greulich, K. M., Lee, K. H., Cram, S., Chapman, V. M. & Gray, J. W., Jun 1994, In : Genomics. 21, 3, p. 641-644 4 p.

Research output: Contribution to journalArticle

56 Scopus citations

Identification of Frequent Novel Genetic Alterations in Small Cell Lung Carcinoma

Levin, N. A., Brzoska, P., Gupta, N., Gray, J. W. & Christman, M. F., Oct 1 1994, In : Cancer Research. 54, 19, p. 5086-5091 6 p.

Research output: Contribution to journalArticle

80 Scopus citations

Increased Copy Number at 20ql3 in Breast Cancer: Defining the Critical Region and Exclusion of Candidate Genes1

Tanner, M. M., Tirkkonen, M., Kallioniemi, A., Collins, C., Stokke, T., Karhu, R., Kowbel, D., Shadravan, F., Hintz, M., Kuo, W. L., Waldman, F. M., Isola, J. J., Gray, J. W. & Kallioniemi, O. P., Aug 1994, In : Cancer Research. 54, 16, p. 4257-4260 4 p.

Research output: Contribution to journalArticle

166 Scopus citations

Interphase cytogenetics of melanocytic neoplasms: numerical aberrations of chromosomes can be detected in interphase nuclei using centromeric DNA probes

Matsuta, M., Matsuta, M., Kon, S., Thompson, C., LeBoit, P. E., Weier, H. U. & Gray, J. W., Feb 1994, In : Journal of cutaneous pathology. 21, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Intracellular dynamics of c‐myc mRNA traffic in single cells in situ

Pallavicini, M. G., George, T., Deteresa, P. S., Amendola, R. & Gray, J. W., Feb 1994, In : Journal of Cellular Physiology. 158, 2, p. 223-230 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Molecular cytogenetics of human breast cancer

Gray, J. W., Collins, C., Henderson, I. C., Isola, J., Kallioniemi, A., Kallioniemi, O. P., Nakamura, H., Pinkel, D., Stokke, T., Tanner, M. & Waldman, F., 1994, In : Cold Spring Harbor symposia on quantitative biology. 59, p. 645-652 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors

Kallioniemi, OP. P., Kallioniemi, A., Piper, J., Isola, J., Waldman, F. M., Gray, J. W. & Pinkel, D., Aug 1994, In : Genes, Chromosomes and Cancer. 10, 4, p. 231-243 13 p.

Research output: Contribution to journalReview article

933 Scopus citations

Physical mapping of chromosome 17 cosmids by fluorescence in situ hybridization and digital image analysis

Kallioniemi, O. P., Kallioniemi, A., Mascio, L., Sudar, D., Pinkel, D., Deaven, L. & Gray, J., Mar 1 1994, In : Genomics. 20, 1, p. 125-128 4 p.

Research output: Contribution to journalArticle

33 Scopus citations

Statement on Use of DNA Testing for Presymptomatic Identification of Cancer Risk

Collins, F. S., Benjamin, L. J., Botstein, D., Cox, J. R., Davidson, N., Gray, J. W., Housman, D. E., Holtzman, N., Jamison, K. R., Rothstein, R., Smith, D. C., Smith, L. M., Spence, M. A. & Tilghman, S. M., Mar 9 1994, In : JAMA: The Journal of the American Medical Association. 271, 10, 1 p.

Research output: Contribution to journalArticle

131 Scopus citations

Thick-section fluorescence in situ hybridization on formalin-fixed, paraffin-embedded archival tissue provides a histogenetic profile

Thompson, C. T., LeBoit, P. E., Nederlof, P. M. & Gray, J. W., Feb 1 1994, In : American Journal of Pathology. 144, 2, p. 237-243 7 p.

Research output: Contribution to journalArticle

61 Scopus citations
1995

Amplification of Chromosomal Region 20ql3 in Invasive Breast Cancer: Prognostic Implications

Tanner, M. M., Tirkkonen, M., Kallioniemi, A., Holli, K., Collins, C., Kowbel, D., Gray, J. W., Kallioniemi, O. P. & Isola, J., Aug 1 1995, In : Clinical Cancer Research. 1, 12, p. 1455-1461 7 p.

Research output: Contribution to journalArticle

127 Scopus citations

A physical map of chromosome 20 established using fluorescence in situ hybridization and digital image analysis

Stokke, T., Collins, C., Kuo, W. L., Kowbel, D., Shadravan, F., Tanner, M., Kallioniemi, A., Kallioniemi, O. P., Pinkel, D., Deaven, L. & Gray, J. W., Jan 1 1995, In : Genomics. 26, 1, p. 134-137 4 p.

Research output: Contribution to journalArticle

57 Scopus citations

Chromosomal localization of the γ-glutamyl carboxylase gene at 2p12

Kuo, W. L., Stafford, D. W., Cruces, J., Gray, J. & Jesú, S., Jan 1 1995, In : Genomics. 25, 3, p. 746-748 3 p.

Research output: Contribution to journalArticle

29 Scopus citations

Computer image analysis of comparative genomic hybridization

Piper, J., Rutovitz, D., Sudar, D., Kallioniemi, A., Kallioniemi, OP. P., Waldman, F. M., Gray, J. W. & Pinkel, D., Jan 1 1995, In : Cytometry. 19, 1, p. 10-26 17 p.

Research output: Contribution to journalArticle

235 Scopus citations

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

Donehower, L. A., Godley, L. A., Aldaz, C. M., Pyle, R., Shi, Y. P., Pinkel, D., Gray, J., Bradley, A., Medina, D. & Varmus, H. E., Apr 1 1995, In : Genes and Development. 9, 7, p. 882-895 14 p.

Research output: Contribution to journalArticle

Open Access
244 Scopus citations

Frequent Novel DNA Copy Number Increase in Squamous Cell Head and Neck Tumors

Brzoska, P. M., Levin, N. A., Fu, K. K., Kaplan, M. J., Singer, M. I., Gray, J. W. & Christman, M. F., Jul 15 1995, In : Cancer Research. 55, 14, p. 3055-3059 5 p.

Research output: Contribution to journalArticle

97 Scopus citations

Genetic Analysis of Benign, Low-Grade, and High-Grade Ovarian Tumors

Iwabuchi, H., Sakamoto, M., Sakunaga, H., Ma, Y. Y., Carcangiu, M. L., Pinkel, D., Yang-Feng, T. L. & Gray, J. W., Dec 15 1995, In : Cancer Research. 55, 24, p. 6172-6180 9 p.

Research output: Contribution to journalArticle

273 Scopus citations

Identification of novel regions of altered DNA copy number in small cell lung tumors

Levin, N. A., Bnorka, P. M., Warnock, M. L., Gray, J. W. & Christman, M. F., Jul 1995, In : Genes, Chromosomes and Cancer. 13, 3, p. 175-185 11 p.

Research output: Contribution to journalArticle

83 Scopus citations

Interactive algorithms for rapid enumeration of hybridization signals in individual whole-cell nuclei inside intact-tissue specimens

Lockett, S. J., Thompson, C. T., Mullikin, J. C., Sudar, D., Khavari, R., Hyun, W., Pinkel, D. & Gray, J. W., Jan 1 1995, Proceedings of SPIE - The International Society for Optical Engineering. Wilson, T. & Cogswell, C. J. (eds.). Society of Photo-Optical Instrumentation Engineers, p. 43-49 7 p. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 2412).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Karyotypic heterogeneity and its relation to labeling index in interphase breast tumor cells

Balazs, M., Matsumura, K., Moore, D., Pinkel, D., Gray, J. W. & Waldman, F. M., May 1 1995, In : Cytometry. 20, 1, p. 62-73 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Quantitative DNA fiber mapping

Weler, H. U. G., Wang, L., Mullikin, J. C., Zhu, Y., Cheng, J. F., Greulich, K. M., Bensimon, A. & Gray, J. W., Oct 1995, In : Human molecular genetics. 4, 10, p. 1903-1910 8 p.

Research output: Contribution to journalArticle

92 Scopus citations

Semiautomated DNA probe mapping using digital imaging microscopy: I. System development

Mascio, L. N., Verbeek, P. W., Sudar, D., Kuo, WL. L. & Gray, J. W., Jan 1 1995, In : Cytometry. 19, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Semiautomated DNA probe mapping using digital imaging microscopy: II. System performance

Sakamoto, M., Pinkel, D., Mascio, L., Sudar, D., Peters, D., Kuo, WL. L., Yamakawa, K., Nakamura, Y., Drabkin, H., Jericevic, Z., Smith, L. & Gray, J. W., Jan 1 1995, In : Cytometry. 19, 1, p. 60-69 10 p.

Research output: Contribution to journalArticle

20 Scopus citations
1996

Cloning, mapping, and in vivo localization of a human member of the PKCI-1 protein family (PRKCNH1)

Brzoska, P. M., Chen, H., Levin, N. A., Kuo, W. L., Collins, C., Fu, K. K., Gray, J. W. & Christman, M. F., Aug 15 1996, In : Genomics. 36, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

High sensitivity, high resolution physical mapping by fluorescence in situ hybridization on to individual straightened DNA molecules

Wang, M., Duell, T., Gray, J. W. & Weier, H. U. G., 1996, In : Bioimaging. 4, 2, p. 73-83 11 p.

Research output: Contribution to journalArticle

15 Scopus citations