• 66579 Citations
  • 112 h-Index
1971 …2020

Research output per year

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Research Output

2018

Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

Risom, T., Langer, E. M., Chapman, M. P., Rantala, J., Fields, A. J., Boniface, C., Alvarez, M. J., Kendsersky, N. D., Pelz, C. R., Johnson-Camacho, K., Dobrolecki, L. E., Chin, K., Aswani, A. J., Wang, N. J., Califano, A., Lewis, M. T., Tomlin, C. J., Spellman, P. T., Adey, A., Gray, J. W. & 1 others, Sears, R. C., Dec 1 2018, In : Nature communications. 9, 1, 3815.

Research output: Contribution to journalArticle

22 Scopus citations

Erratum: Publisher Correction: Combating subclonal evolution of resistant cancer phenotypes (Nature communications (2017) 8 1 (1231))

Brady, S. W., McQuerry, J. A., Qiao, Y., Piccolo, S. R., Shrestha, G., Jenkins, D. F., Layer, R. M., Pedersen, B. S., Miller, R. H., Esch, A., Selitsky, S. R., Parker, J. S., Anderson, L. A., Dalley, B. K., Factor, R. E., Reddy, C. B., Boltax, J. P., Li, D. Y., Moos, P. J., Gray, J. W. & 8 others, Heiser, L. M., Buys, S. S., Cohen, A. L., Johnson, W. E., Quinlan, A. R., Marth, G., Werner, T. L. & Bild, A. H., Feb 5 2018, In : Nature communications. 9, 1, 1 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

Lack of acquired resistance in HER2-positive breast cancer cells after long-term HER2 siRNA nanoparticle treatment

Gu, S., Ngamcherdtrakul, W., Reda, M., Hu, Z., Gray, J. & Yantasee, W., Jun 1 2018, In : PLoS One. 13, 6, e0198141.

Research output: Contribution to journalArticle

3 Scopus citations

MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection

Rozanov, D., Rozanov, N. D., Chiotti, K. E., Reddy, A., Wilmarth, P., David, L., Cha, S. W., Woo, S., Pevzner, P., Bafna, V., Burrows, G. G., Rantala, J. K., Levin, T., Anur, P., Johnson-Camacho, K., Tabatabaei, S., Munson, D. J., Bruno, T. C., Slansky, J. E., Kappler, J. W. & 9 others, Hirano, N., Boegel, S., Fox, B. A., Egelston, C., Simons, D. L., Jimenez, G., Lee, P. P., Gray, J. & Spellman, P., Mar 30 2018, In : Journal of Proteomics. 176, p. 13-23 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes

Watson, S. S., Dane, M., Chin, K-Y., Tatarova, Z., Liu, M., Liby, T., Thompson, W., Smith, R., Nederlof, M., Bucher, E., Kilburn, D., Whitman, M., Sudar, D., Mills, G., Heiser, L., Jonas, O., Gray, J. & Korkola, J., Jan 1 2018, (Accepted/In press) In : Cell Systems.

Research output: Contribution to journalArticle

10 Scopus citations

Molecular Cytogenetics Guides Massively Parallel Sequencing of a Radiation-Induced Chromosome Translocation in Human Cells

Cornforth, M. N., Anur, P., Wang, N., Robinson, E., Ray, F. A., Bedford, J. S., Loucas, B. D., Williams, E. S., Peto, M., Spellman, P., Kollipara, R., Kittler, R., Gray, J. & Bailey, S. M., Jul 1 2018, In : Radiation Research. 190, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

SHIFT: Speedy histopathological-To-immunofluorescent translation of whole slide images using conditional generative adversarial networks

Burlingame, E. A., Margolin, A., Gray, J. & Chang, Y. H., Jan 1 2018, Medical Imaging 2018: Digital Pathology. SPIE, Vol. 10581. 1058105

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Simultaneous Multicolor Single-Molecule Tracking with Single-Laser Excitation via Spectral Imaging

Huang, T., Phelps, C., Wang, J., Lin, L. J., Bittel, A., Scott, Z., Jacques, S., Gibbs, S., Gray, J. & Nan, X., Jan 23 2018, In : Biophysical Journal. 114, 2, p. 301-310 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution

Cheng, J. B., Sedgewick, A. J., Finnegan, A. I., Harirchian, P., Lee, J., Kwon, S., Fassett, M. S., Golovato, J., Gray, M., Ghadially, R., Liao, W., Perez White, B. E., Mauro, T. M., Mully, T., Kim, E. A., Sbitany, H., Neuhaus, I. M., Grekin, R. C., Yu, S. S., Gray, J. W. & 6 others, Purdom, E., Paus, R., Vaske, C. J., Benz, S. C., Song, J. S. & Cho, R. J., Oct 23 2018, In : Cell Reports. 25, 4, p. 871-883 13 p.

Research output: Contribution to journalArticle

19 Scopus citations
2019

Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer

Butler, T. M., Boniface, C. T., Johnson-Camacho, K., Tabatabaei, S., Melendez, D., Kelley, T., Gray, J., Corless, C. L. & Spellman, P. T., Jan 1 2019, In : Cold Spring Harbor Molecular Case Studies. 5, 2, a003772.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

cmIF: A Python Library for Scalable Multiplex Imaging Pipelines

Eng, J., Bucher, E., Gray, E., Campbell, L. G., Thibault, G., Heiser, L., Gibbs, S., Gray, J. W., Chin, K. & Chang, Y. H., Jan 1 2019, Mathematical and Computational Oncology - 1st International Symposium, ISMCO 2019, Proceedings. Bebis, G., Benos, T., Chen, K., Jahn, K. & Lima, E. (eds.). Springer, p. 37-43 7 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11826 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters

Sutton, M. N., Lu, Z., Li, Y. C., Zhou, Y., Huang, T., Reger, A. S., Hurwitz, A. M., Palzkill, T., Logsdon, C., Liang, X., Gray, J. W., Nan, X., Hancock, J., Wahl, G. M. & Bast, R. C., Dec 10 2019, In : Cell Reports. 29, 11, p. 3448-3459.e6

Research output: Contribution to journalArticle

Open Access

High-throughput single-particle tracking reveals 1 nested membrane domains that dictate krasg12d 2 diffusion and trafficking

Lee, Y., Phelps, C., Huang, T., Mostofian, B., Wu, L., Zhang, Y., Tao, K., Chang, Y. H., Stork, P. J. S., Gray, J. W., Zuckerman, D. M. & Nan, X., Nov 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting

Langer, E. M., Allen-Petersen, B. L., King, S. M., Kendsersky, N. D., Turnidge, M. A., Kuziel, G. M., Riggers, R., Samatham, R., Amery, T. S., Jacques, S. L., Sheppard, B. C., Korkola, J. E., Muschler, J. L., Thibault, G., Chang, Y. H., Gray, J. W., Presnell, S. C., Nguyen, D. G. & Sears, R. C., Jan 15 2019, In : Cell Reports. 26, 3, p. 608-623.e6

Research output: Contribution to journalArticle

11 Scopus citations

PLK1 and EGFR targeted nanoparticle as a radiation sensitizer for non-small cell lung cancer

Reda, M., Ngamcherdtrakul, W., Gu, S., Bejan, D. S., Siriwon, N., Gray, J. W. & Yantasee, W., Dec 28 2019, In : Cancer Letters. 467, p. 9-18 10 p.

Research output: Contribution to journalArticle

Robust Cell Detection and Segmentation for Image Cytometry Reveal Th17 Cell Heterogeneity

Tsujikawa, T., Thibault, G., Azimi, V., Sivagnanam, S., Banik, G., Means, C., Kawashima, R., Clayburgh, D. R., Gray, J. W., Coussens, L. M. & Chang, Y. H., Apr 2019, In : Cytometry Part A. 95, 4, p. 389-398 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Signal removal methods for highly multiplexed immunofluorescent staining using antibody conjugated oligonucleotides

McMahon, N., Jones, J., Eng, J., Kwon, S., Chang, Y. H., Thibault, G., Chin, K., Nederlof, M., Gray, J. & Gibbs, S. L., Jan 1 2019, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVII. Leary, J. F., Tarnok, A. & Farkas, D. L. (eds.). SPIE, 108810X. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10881).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Targeting mitochondria in cancer therapy could provide a basis for the selective anticancer activity

Rozanov, D., Cheltsov, A., Nilsen, A., Boniface, C., Forquer, I., Korkola, J., Gray, J., Tyner, J., Tognon, C. E., Mills, G. & Spellman, P., Mar 1 2019, In : PloS one. 14, 3, e0205623.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Targeting the mevalonate pathway to overcome acquired anti-HER2 treatment resistance in breast cancer

Sethunath, V., Hu, H., De Angelis, C., Veeraraghavan, J., Qin, L., Wang, N., Simon, L. M., Wang, T., Fu, X., Nardone, A., Pereira, R., Nanda, S., Griffith, O. L., Tsimelzon, A., Shaw, C., Chamness, G. C., Reis-Filho, J. S., Weigelt, B., Heiser, L. M., Hilsenbeck, S. G. & 5 others, Huang, S., Rimawi, M. F., Gray, J. W., Osborne, C. K. & Schiff, R., Jan 1 2019, In : Molecular Cancer Research. 17, 11, p. 2318-2330 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Therapeutic Clues from an Integrated Omic Assessment of East Asian Triple Negative Breast Cancers

Heiser, L. M., Mills, G. B. & Gray, J. W., Mar 18 2019, In : Cancer Cell. 35, 3, p. 341-343 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Variational autoencoding tissue response to microenvironment perturbation

Schau, G. F., Thibault, G., Dane, M. A., Gray, J., Heiser, L. & Chang, Y. H., Jan 1 2019, Medical Imaging 2019: Image Processing. Landman, B. A., Angelini, E. D., Angelini, E. D. & Angelini, E. D. (eds.). SPIE, 109491M. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10949).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2020

A workflow for visualizing human cancer biopsies using large-format electron microscopy

Riesterer, J. L., López, C. S., Stempinski, E. S., Williams, M., Loftis, K., Stoltz, K., Thibault, G., Lanicault, C., Williams, T. & Gray, J. W., 2020, Methods in Cell Biology. Tran, P. (ed.). Academic Press Inc., p. 163-181 19 p. (Methods in Cell Biology; vol. 158).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Fluorescent imaging technologies for in situ measurement of drug target engagement and cell signaling pathways

McMahon, N. P., Solanki, A., Jones, J., Kwon, S., Chang, Y. H., Chin, K., Nederlof, M. A., Gray, J. W. & Gibbs, S. L., Jan 1 2020, Visualizing and Quantifying Drug Distribution in Tissue IV. Chan, K. F. & Evans, C. L. (eds.). SPIE, 112190O. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11219).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Predicting primary site of secondary liver cancer with a neural estimator of metastatic origin

Schau, G. F., Burlingame, E. A., Thibault, G., Anekpuritanang, T., Wang, Y., Gray, J. W., Corless, C. & Chang, Y. H., Jan 1 2020, In : Journal of Medical Imaging. 7, 1, 012706.

Research output: Contribution to journalArticle

RESTORE: Robust intEnSiTy nORmalization mEthod for multiplexed imaging

Chang, Y. H., Chin, K., Thibault, G., Eng, J., Burlingame, E. & Gray, J. W., Dec 1 2020, In : Communications Biology. 3, 1, 111.

Research output: Contribution to journalArticle

Open Access