Jodi McBride

Assistant Professor

  • 3553 Citations
  • 17 h-Index
1978 …2021
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Research Output 2000 2019

  • 3553 Citations
  • 17 h-Index
  • 21 Article
  • 2 Chapter
  • 1 Review article
2019
Huntington Disease
Glucocorticoids
Corticosterone
Hydrocortisone
Adrenalectomy
2018
1 Citation (Scopus)

Discovery of a CLN7 model of Batten disease in non-human primates

McBride, J., Neuringer, M., Ferguson, B., Kohama, S., Tagge, I. J., Zweig, R. C., Renner, L. M., McGill, T., Stoddard, J., Peterson, S., Su, W., Sherman, L. L., Domire, J. S., Ducore, R., Colgin, L. & Lewis, A., Nov 1 2018, In : Neurobiology of Disease. 119, p. 65-78 14 p.

Research output: Contribution to journalArticle

Neuronal Ceroid-Lipofuscinoses
Macaca
Primates
Ataxia
Genes
2016
2 Citations (Scopus)

Corticosterone dysregulation exacerbates disease progression in the R6/2 transgenic mouse model of Huntington's disease

Dufour, B. D. & McBride, J., Sep 1 2016, In : Experimental Neurology. 283, p. 308-317 10 p.

Research output: Contribution to journalArticle

Huntington Disease
Corticosterone
Transgenic Mice
Disease Progression
Adrenalectomy
40 Citations (Scopus)

Gene suppression strategies for dominantly inherited neurodegenerative diseases: lessons from Huntington's disease and spinocerebellar ataxia

Keiser, M. S., Kordasiewicz, H. B. & McBride, J., Apr 15 2016, In : Human Molecular Genetics. 25, R1, p. R53-R64

Research output: Contribution to journalReview article

Spinocerebellar Ataxias
Huntington Disease
Neurodegenerative Diseases
Genes
Genetic Therapy
3 Citations (Scopus)

Intravascular AAV9 administration for delivering RNA silencing constructs to the CNS and periphery

Dufour, B. D. & McBride, J., 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1364. p. 261-275 15 p. (Methods in Molecular Biology; vol. 1364).

Research output: Chapter in Book/Report/Conference proceedingChapter

Dependovirus
RNA Interference
Central Nervous System
Blood-Brain Barrier
Jugular Veins
3 Citations (Scopus)

Stereotaxic surgical targeting of the nonhuman primate caudate and putamen: Gene therapy for huntington’s disease

McBride, J. & Clark, R. L., 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1382. p. 409-428 20 p. (Methods in Molecular Biology; vol. 1382).

Research output: Chapter in Book/Report/Conference proceedingChapter

Putamen
Huntington Disease
Genetic Therapy
Primates
Inborn Genetic Diseases
2015
1 Citation (Scopus)

Viral vector mediated expression of mutant huntingtin in the dorsal raphe produces disease-related neuropathology but not depressive-like behaviors in wildtype mice

Pitzer, M., Lueras, J., Warden, A., Weber, S. & McBride, J., May 22 2015, In : Brain Research. 1608, p. 177-190 14 p.

Research output: Contribution to journalArticle

Huntington Disease
Depression
Serotonin
Mutation
Brain
2014
33 Citations (Scopus)

Intrajugular VEIN DELIVERY OF AAV9-RNAi prevents neuropathological changes and weight loss in huntington's disease mice

Dufour, B. D., Smith, C. A., Clark, R. L., Walker, T. R. & McBride, J., 2014, In : Molecular Therapy. 22, 4, p. 797-810 14 p.

Research output: Contribution to journalArticle

Huntington Disease
RNA Interference
Weight Loss
Mutant Proteins
Corpus Striatum
11 Citations (Scopus)

Single nucleotide seed modification restores in vivo tolerability of a toxic artificial miRNA sequence in the mouse brain

Monteys, A. M. A., Spengler, R. M., Dufour, B. D., Wilson, M. S., Oakley, C. K., Sowada, M. J., McBride, J. & Davidson, B. L., Dec 1 2014, In : Nucleic Acids Research. 42, 21, p. 13315-13327 13 p.

Research output: Contribution to journalArticle

Poisons
MicroRNAs
Seeds
Nucleotides
RNA Interference
2012
144 Citations (Scopus)

Mutant Huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

Shirendeb, U. P., Calkins, M. J., Manczak, M., Anekonda, V., Dufour, B., McBride, J., Mao, P. & Reddy, P. H., Jan 2012, In : Human Molecular Genetics. 21, 2, p. 406-420 15 p., ddr475.

Research output: Contribution to journalArticle

Axonal Transport
Mitochondrial Dynamics
Mitochondrial Proteins
Huntington Disease
Organelle Biogenesis
2011
128 Citations (Scopus)

Preclinical safety of RNAi-mediated HTT suppression in the rhesus macaque as a potential therapy for Huntington's disease

McBride, J., Pitzer, M. R., Boudreau, R. L., Dufour, B., Hobbs, T., Ojeda, S. & Davidson, B. L., Dec 2011, In : Molecular Therapy. 19, 12, p. 2152-2162 11 p.

Research output: Contribution to journalArticle

Putamen
Huntington Disease
RNA Interference
Macaca mulatta
Safety
2009
40 Citations (Scopus)

Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease

Ramaswamy, S., McBride, J., Han, I., Berry-Kravis, E. M., Zhou, L., Herzog, C. D., Gasmi, M., Bartus, R. T. & Kordower, J. H., Apr 2009, In : Neurobiology of Disease. 34, 1, p. 40-50 11 p.

Research output: Contribution to journalArticle

Neurturin
Corpus Striatum
Huntington Disease
Motor Neurons
Transgenic Mice
227 Citations (Scopus)

Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice

Boudreau, R. L., McBride, J., Martins, I., Shen, S., Xing, Y., Carter, B. J. & Davidson, B. L., 2009, In : Molecular Therapy. 17, 6, p. 1053-1063 11 p.

Research output: Contribution to journalArticle

Huntington Disease
RNA Interference
Therapeutics
Mutant Proteins
Neurodegenerative Diseases
66 Citations (Scopus)

Transduction of nonhuman primate brain with adeno-associated virus serotype 1: Vector trafficking and immune response

Hadaczek, P., Forsayeth, J., Mirek, H., Munson, K., Bringas, J., Pivirotto, P., McBride, J., Davidson, B. L. & Bankiewicz, K. S., Mar 1 2009, In : Human Gene Therapy. 20, 3, p. 225-237 13 p.

Research output: Contribution to journalArticle

Dependovirus
Primates
Brain
Haplorhini
Renilla
2008
401 Citations (Scopus)

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi

McBride, J., Boudreau, R. L., Harper, S. Q., Staber, P. D., Monteys, A. M., Martins, I., Gilmore, B. L., Burstein, H., Peluso, R. W., Polisky, B., Carter, B. J. & Davidson, B. L., Apr 15 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 15, p. 5868-5873 6 p.

Research output: Contribution to journalArticle

Huntington Disease
MicroRNAs
Small Interfering RNA
Brain
Antisense RNA
52 Citations (Scopus)

Restoring acid-sensing ion channel-1a in the amygdala of knock-out mice rescues fear memory but not unconditioned fear responses

Coryell, M. W., Wunsch, A. M., Haenfler, J. M., Allen, J. E., McBride, J., Davidson, B. L. & Wemmie, J. A., Dec 17 2008, In : Journal of Neuroscience. 28, 51, p. 13738-13741 4 p.

Research output: Contribution to journalArticle

Acid Sensing Ion Channels
Amygdala
Knockout Mice
Fear
Freezing
2007
132 Citations (Scopus)

Animal models of Huntington's disease

Ramaswamy, S., McBride, J. & Kordower, J. H., 2007, In : ILAR Journal. 48, 4, p. 356-373 18 p.

Research output: Contribution to journalArticle

animal disease models
Huntington Disease
Animals
Animal Models
Pathology
28 Citations (Scopus)

Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease

Ramaswamy, S., McBride, J., Herzog, C. D., Brandon, E., Gasmi, M., Bartus, R. T. & Kordower, J. H., May 2007, In : Neurobiology of Disease. 26, 2, p. 375-384 10 p.

Research output: Contribution to journalArticle

Neurturin
Corpus Striatum
Huntington Disease
Genetic Therapy
Neurons
812 Citations (Scopus)

Transvascular delivery of small interfering RNA to the central nervous system

Kumar, P., Wu, H., McBride, J., Jung, K. E., Hee Kim, M., Davidson, B. L., Kyung Lee, S., Shankar, P. & Manjunath, N., Jul 7 2007, In : Nature. 448, 7149, p. 39-43 5 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Rabies virus
Central Nervous System
Glycoproteins
Gene Silencing
2006
84 Citations (Scopus)

Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease

McBride, J., Ramaswamy, S., Gasmi, M., Bartus, R. T., Herzog, C. D., Brandon, E. P., Zhou, L., Pitzer, M. R., Berry-Kravis, E. M. & Kordower, J. H., Jun 13 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 24, p. 9345-9350 6 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Corpus Striatum
Huntington Disease
Neurons
Trinucleotide Repeat Expansion
2004
183 Citations (Scopus)

Human neural stem cell transplants improve motor function in a rat model of Huntington's disease

McBride, J., Behrstock, S. P., Chen, E. Y., Jakel, R. J., Siegel, I., Svendsen, C. N. & Kordower, J. H., Jul 19 2004, In : Journal of Comparative Neurology. 475, 2, p. 211-219 9 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Huntington Disease
Corpus Striatum
Transplants
Ciliary Neurotrophic Factor
2003
74 Citations (Scopus)

Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF

McBride, J., During, M. J., Wuu, J., Chen, E. Y., Leurgans, S. E. & Kordower, J. H., Jun 1 2003, In : Experimental Neurology. 181, 2, p. 213-223 11 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Viral Genes
Huntington Disease
Corpus Striatum
Neurons
2002
33 Citations (Scopus)

Neuroprotection for Parkinson's disease using viral vector-mediated delivery of GDNF

McBride, J. & Kordower, J. H., 2002, In : Progress in Brain Research. 138, p. 421-432 12 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Genetic Vectors
Nerve Growth Factors
Neuroprotective Agents
Genetic Therapy
2000
1055 Citations (Scopus)

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

Kordower, J. H., Emborg, M. E., Bloch, J., Ma, S. Y., Chu, Y., Leventhal, L., McBride, J., Chen, E. Y., Palfi, S., Roitberg, B. Z., Brown, W. D., Holden, J. E., Pyzalski, R., Taylor, M. D., Carvey, P., Ling, Z., Trono, D., Hantraye, P., Deglon, N. & Aebischer, P., Oct 27 2000, In : Science. 290, 5492, p. 767-773 7 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Primates
Parkinson Disease
Macaca mulatta
Haplorhini