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  • 4 Similar Profiles
Huntington Disease Medicine & Life Sciences
Brain Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
RNA Interference Medicine & Life Sciences
Corpus Striatum Medicine & Life Sciences
Primates Medicine & Life Sciences
Neurons Medicine & Life Sciences
Glial Cell Line-Derived Neurotrophic Factor Medicine & Life Sciences

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Projects 1978 2021

Huntington Disease
Basal Ganglia
Primates
Corpus Striatum
Gliosis

Global RNA Interference Therapy for Huntingtons Disease

McBride, J.

National Institutes of Health

9/1/168/31/17

Project: Research projectExploratory/Developmental Grants

Huntington Disease
RNA Interference
Therapeutics
Brain
Cisterna Magna

Non-alledle specific RNAi as a potential therapy for Huntington's disease

McBride, J.

National Institutes of Health

8/11/078/1/09

Project: Research projectPostdoctoral Individual National Research Service Award

Huntington Disease
RNA Interference
Therapeutics
Corpus Striatum
Alleles

REPRODUCTIVE STEROIDS AND EXPERIMENTAL STROKE

Ronnekleiv, O., Hess, D., Casey, D., Duell, P., Machida, C., Dissen, G., Moses, A., Nelson, J., Kohama, S., Wong, S., Urbanski, H., Spindel, E., Stouffer, R., Smith, M. (., Axthelm, M., Neuringer, M., Ojeda, S., Bethea, C., Grove, K., Zelinski, M., Patton, P., Grove, K., Hess, D., Zelinski, M., Orloff, S., Mitalipov, S., Ronnekleiv, O., Lee, D., Coleman, K., Jensen, J., Grove, K., Slayden, O., Picker, L., Sherman, L. (., Zelinski, M., Hennebold, J., Slifka, M., Banine, F., Gruber, A., Wright, J., Ferguson, B., Cornea, A., Grant, K. (., Dissen, G., Lomniczi, A., De Filippis, V., Xu, F., Mitalipov, S., Edelman, A., Haigwood, N., Grigsby, P., Roberts, C., Streblow, D., Kroenke, C. (., Rasanen, J., Lee, D., Lewis, A., Frueh, K., Morrison, S., Reddy, P. (., Helms, C., Cornea, A., Coleman, K., Carbone, L., Lindner, J., McBride, J., Brambrink, A., Sullivan, E., Mallley, A., Beatty, C., Phoenix, C., Funan, H., Fahrenbach, W., Alexander, N., Portman, O., Howard, C., Palotay, J., Egerer, C., Gliessman, P., Critchlow, B. V., Webb, M., Burnham, J., Hill, J., Janina, E., Toyooka, A., McDonald, I., Resko, J., Melner, M., Hermsmeyer, K., Olson, L., McNulty, W., Malinow, R., Kelley, S., Maslar, I., Joel, I., Hoskins, D., Saneto, R., Ellinwood, W., Towne, D., Critchlow, V., Coffin, R., Koler, R., Laster, L., Malley, A., Kohler, P., Sorensen, T., Lentz, S., Schatten, G., Spence, J. C., Rxnnekleiv, O., Reimann, K., Beer, B., Rajkovic, A., Duffy, D., Sadowsky, D., Shiigi, S., Stouffer Richard, L., Matrisian, L., Toole, J., Meng, L., Kohler, P. O., Robertson, J., R Nnekleiv, O., Ridker, P., Shimakawa, T., Karlsson, G., Gravett, M., Hirsch, V., Garg, R., Folsom, A., Gerhard, G., Verhage, H., Murphy, S., Hermsmeyer, R. K., Haluska, G., Hirsch, V., Garg, R., Novy, M. J., Folsom, A., Gerhard, G., Karlsson, G., Gravett, M., Verhage, H., Lewinsohn, D., Lewinsohn, D. M., Letvin, N., Yoshihara, P. H., Rodland, K. D., Sodroski, J., Smith, E., Vitetta, E., Clark, A., K-Y Francis, P., Gravett, M., Cowley, M., Novy, M. J., Frueh, K., Nikolich-Zugich, J., Cowley, D., Adamus, G., [No Value], V. Z., Hanson, S., Lewinsohn, D., Xuemei, W., Adams Waldorf, K., Mayerhofer, A., Sadowsky, D., Dubay, C., Jeffrey, B., Messaoudi, I., Song, P., Matagne, V., Madden, C., Stenzel-Poore, M., Doane, C., Frueh, K., Hoffman, G., Jung, H., McCarron, D., Herzlich, B., Watanabe, M., Nagalla, S., Kronzon, I., Drake, T., Sakata, H., Jennes, L., Gerald, L., Aach, J., Vijayaraghavan, S., Smith, G., Eaton, G., Schwartz, S., Hermsmeyer, R. K., Haluska, G., Novy, M., Spies, H., Kodama, T., Kittner, S., Brenner, R., Simerly, R., Mayerhofer, A., Malinow, M., Wolf, D., Conn, P. M., Cameron, J., Lewinsohn, D., Lewinsohn, D. & Madden, C. (.

National Institutes of Health

5/1/784/30/14

Project: Research projectPrimate Research Center Grants, Research Scientist Development Award - Research & Training

Research
Hormones
Steroids
Estrogens
Dopamine

Research Output 2000 2016

  • 3121 Citations
  • 16 h-Index
  • 19 Article
  • 2 Chapter
  • 1 Review article

Corticosterone dysregulation exacerbates disease progression in the R6/2 transgenic mouse model of Huntington's disease

Dufour, B. D. & McBride, J. L. Sep 1 2016 In : Experimental Neurology. 283, p. 308-317 10 p.

Research output: Research - peer-reviewArticle

Huntington Disease
Corticosterone
Transgenic Mice
Disease Progression
Adrenalectomy
14 Citations

Gene suppression strategies for dominantly inherited neurodegenerative diseases: lessons from Huntington's disease and spinocerebellar ataxia

Keiser, M. S., Kordasiewicz, H. B. & McBride, J. L. Apr 15 2016 In : Human molecular genetics. 25, R1, p. R53-R64

Research output: Research - peer-reviewReview article

Spinocerebellar Ataxias
Huntington Disease
Neurodegenerative Diseases
Genes
Genetic Therapy
1 Citations

Intravascular AAV9 administration for delivering RNA silencing constructs to the CNS and periphery

Dufour, B. D. & McBride, J. L. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1364, p. 261-275 15 p. (Methods in Molecular Biology; vol. 1364)

Research output: ResearchChapter

Dependovirus
RNA Interference
Central Nervous System
Serogroup
Blood-Brain Barrier

Stereotaxic surgical targeting of the nonhuman primate caudate and putamen: Gene therapy for huntington’s disease

McBride, J. L. & Clark, R. L. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1382, p. 409-428 20 p. (Methods in Molecular Biology; vol. 1382)

Research output: ResearchChapter

Putamen
Huntington Disease
Genetic Therapy
Primates
Inborn Genetic Diseases

Viral vector mediated expression of mutant huntingtin in the dorsal raphe produces disease-related neuropathology but not depressive-like behaviors in wildtype mice

Pitzer, M., Lueras, J., Warden, A., Weber, S. & McBride, J. May 22 2015 In : Brain Research. 1608, p. 177-190 14 p.

Research output: Research - peer-reviewArticle

Huntington Disease
Dorsal Raphe Nucleus
Neuropathology
Depression
Serotonin