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  • 6 Similar Profiles
Huntington Disease Medicine & Life Sciences
Corpus Striatum Medicine & Life Sciences
Glial Cell Line-Derived Neurotrophic Factor Medicine & Life Sciences
RNA Interference Medicine & Life Sciences
Brain Medicine & Life Sciences
Primates Medicine & Life Sciences
Neurturin Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences

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Projects 1978 2021

Huntington Disease
Basal Ganglia
Primates
Corpus Striatum
Gliosis

Global RNA Interference Therapy for Huntingtons Disease

McBride, J.

National Institutes of Health

9/1/168/31/17

Project: Research projectExploratory/Developmental Grants

Huntington Disease
RNA Interference
Therapeutics
Brain
Cisterna Magna

Non-alledle specific RNAi as a potential therapy for Huntington's disease

McBride, J.

National Institutes of Health

8/11/078/1/09

Project: Research projectPostdoctoral Individual National Research Service Award

Huntington Disease
Corpus Striatum
RNA Interference
Alleles
Small Interfering RNA

REPRODUCTIVE STEROIDS AND EXPERIMENTAL STROKE

Ronnekleiv, O., Hess, D., Casey, D., Duell, P., Machida, C., Dissen, G., Moses, A., Nelson, J., Kohama, S., Wong, S., Urbanski, H., Spindel, E., Stouffer, R., Smith, M. (., Axthelm, M., Neuringer, M., Ojeda, S., Bethea, C., Grove, K., Zelinski, M., Patton, P., Grove, K., Hess, D., Zelinski, M., Orloff, S., Mitalipov, S., Ronnekleiv, O., Lee, D., Coleman, K., Jensen, J., Grove, K., Slayden, O., Picker, L., Sherman, L. (., Zelinski, M., Hennebold, J., Slifka, M., Banine, F., Gruber, A., Wright, J., Ferguson, B., Cornea, A., Grant, K. (., Dissen, G., Lomniczi, A., De Filippis, V., Xu, F., Mitalipov, S., Edelman, A., Haigwood, N., Grigsby, P., Roberts, C., Streblow, D., Kroenke, C. (., Rasanen, J., Lee, D., Lewis, A., Frueh, K., Morrison, S., Reddy, P. (., Helms, C., Cornea, A., Coleman, K., Carbone, L., Lindner, J., McBride, J., Brambrink, A., Sullivan, E., Mallley, A., Beatty, C., Phoenix, C., Funan, H., Fahrenbach, W., Alexander, N., Portman, O., Howard, C., Palotay, J., Egerer, C., Gliessman, P., Critchlow, B. V., Webb, M., Burnham, J., Hill, J., Janina, E., Toyooka, A., McDonald, I., Resko, J., Melner, M., Hermsmeyer, K., Olson, L., McNulty, W., Malinow, R., Kelley, S., Maslar, I., Joel, I., Hoskins, D., Saneto, R., Ellinwood, W., Towne, D., Critchlow, V., Coffin, R., Koler, R., Laster, L., Malley, A., Kohler, P., Sorensen, T., Lentz, S., Schatten, G., Spence, J. C., Rxnnekleiv, O., Reimann, K., Beer, B., Rajkovic, A., Duffy, D., Sadowsky, D., Shiigi, S., Stouffer Richard, L., Matrisian, L., Toole, J., Meng, L., Kohler, P. O., Robertson, J., R Nnekleiv, O., Ridker, P., Shimakawa, T., Karlsson, G., Gravett, M., Hirsch, V., Garg, R., Folsom, A., Gerhard, G., Verhage, H., Murphy, S., Hermsmeyer, R. K., Haluska, G., Hirsch, V., Garg, R., Novy, M. J., Folsom, A., Gerhard, G., Karlsson, G., Gravett, M., Verhage, H., Lewinsohn, D., Lewinsohn, D. M., Letvin, N., Yoshihara, P. H., Rodland, K. D., Sodroski, J., Smith, E., Vitetta, E., Clark, A., K-Y Francis, P., Gravett, M., Cowley, M., Novy, M. J., Frueh, K., Nikolich-Zugich, J., Cowley, D., Adamus, G., [No Value], V. Z., Hanson, S., Lewinsohn, D., Xuemei, W., Adams Waldorf, K., Mayerhofer, A., Sadowsky, D., Dubay, C., Jeffrey, B., Messaoudi, I., Song, P., Matagne, V., Madden, C., Stenzel-Poore, M., Doane, C., Frueh, K., Hoffman, G., Jung, H., McCarron, D., Herzlich, B., Watanabe, M., Nagalla, S., Kronzon, I., Drake, T., Sakata, H., Jennes, L., Gerald, L., Aach, J., Vijayaraghavan, S., Smith, G., Eaton, G., Schwartz, S., Hermsmeyer, R. K., Haluska, G., Novy, M., Spies, H., Kodama, T., Kittner, S., Brenner, R., Simerly, R., Mayerhofer, A., Malinow, M., Wolf, D., Conn, P. M., Cameron, J., Lewinsohn, D., Lewinsohn, D. & Madden, C. (.

National Institutes of Health

5/1/784/30/14

Project: Research projectPrimate Research Center Grants, Research Scientist Development Award - Research & Training

Middle Cerebral Artery Infarction
Hormones
Primates
Estrogens
Steroids

Research Output 2000 2016

  • 3252 Citations
  • 17 h-Index
  • 19 Article
  • 2 Chapter
  • 1 Review article

Corticosterone dysregulation exacerbates disease progression in the R6/2 transgenic mouse model of Huntington's disease

Dufour, B. D. & McBride, J. L. Sep 1 2016 In : Experimental Neurology. 283, p. 308-317 10 p.

Research output: Contribution to journalArticle

Huntington Disease
Corticosterone
Transgenic Mice
Disease Progression
Adrenalectomy
18 Citations

Gene suppression strategies for dominantly inherited neurodegenerative diseases: lessons from Huntington's disease and spinocerebellar ataxia

Keiser, M. S., Kordasiewicz, H. B. & McBride, J. L. Apr 15 2016 In : Human molecular genetics. 25, R1, p. R53-R64

Research output: Contribution to journalReview article

Spinocerebellar Ataxias
Huntington Disease
Neurodegenerative Diseases
Genes
Genetic Therapy
2 Citations

Intravascular AAV9 administration for delivering RNA silencing constructs to the CNS and periphery

Dufour, B. D. & McBride, J. L. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1364, p. 261-275 15 p. (Methods in Molecular Biology; vol. 1364)

Research output: Chapter in Book/Report/Conference proceedingChapter

Dependovirus
RNA Interference
Central Nervous System
Blood-Brain Barrier
Jugular Veins
2 Citations

Stereotaxic surgical targeting of the nonhuman primate caudate and putamen: Gene therapy for huntington’s disease

McBride, J. L. & Clark, R. L. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1382, p. 409-428 20 p. (Methods in Molecular Biology; vol. 1382)

Research output: Chapter in Book/Report/Conference proceedingChapter

Putamen
Huntington Disease
Genetic Therapy
Primates
Inborn Genetic Diseases

Viral vector mediated expression of mutant huntingtin in the dorsal raphe produces disease-related neuropathology but not depressive-like behaviors in wildtype mice

Pitzer, M., Lueras, J., Warden, A., Weber, S. & McBride, J. May 22 2015 In : Brain Research. 1608, p. 177-190 14 p.

Research output: Contribution to journalArticle

Huntington Disease
Depression
Serotonin
Mutation
Brain