Jinu Abraham

Staff Scientist 1

  • 458 Citations
  • 10 h-Index
20102018
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Research Output 2010 2018

  • 458 Citations
  • 10 h-Index
  • 23 Article

Emerging alphaviruses are sensitive to cellular states induced by a novel small-molecule agonist of the STING pathway

Gall, B., Pryke, K., Abraham, J., Mizuno, N., Botto, S., Sali, T. M., Broeckel, R., Haese, N., Nilsen, A., Placzek, A., Morrison, T., Heise, M., Streblow, D. & DeFilippis, V., Mar 1 2018, In : Journal of Virology. 92, 6, e01913-17

Research output: Contribution to journalArticle

Alphavirus
interferons
Interferons
agonists
Interferon Type I
6 Citations

A novel agonist of the trif pathway induces a cellular state refractory to replication of Zika, Chikungunya, and dengue viruses

Pryke, K. M., Abraham, J., Sali, T. M., Gall, B. J., Archer, I., Liu, A., Bambina, S., Baird, J., Gough, M., Chakhtoura, M., Haddad, E. K., Kirby, I. T., Nilsen, A., Streblow, D. N., Hirsch, A. J., Smith, J. L. & Defilippis, V. R., May 1 2017, In : mBio. 8, 3, e00452-17

Research output: Contribution to journalArticle

Chikungunya virus
Dengue Virus
Interferon Type I
Adaptive Immunity
Interferon Regulatory Factor-3
3 Citations

IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma

Svalina, M. N. , Kikuchi, K. , Abraham, J. , Lal, S. , Davare, M. A. , Settelmeyer, T. P. , Young, M. C. , Peckham, J. L. , Cho, Y. J. , Michalek, J. E. , Hernandez, B. S. , Berlow, N. E. , Jackson, M. , Guillaume, D. J. , Selden, N. R. , Bigner, D. D. , Nazemi, K. J. , Green, S. C. , Corless, C. L. , Gultekin, S. & 4 others Mansoor, A., Rubin, B. P., Woltjer, R. & Keller, C., Jun 3 2016, In : Scientific Reports. 6, 27012

Research output: Contribution to journalArticle

Medulloblastoma
Peptide Hydrolases
Cerebrospinal Fluid
Neoplasm Metastasis
Plasminogen Activator Inhibitor 1
16 Citations

Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses

Sali, T. M., Pryke, K. M., Abraham, J., Liu, A., Archer, I., Broeckel, R., Staverosky, J. A., Smith, J. L., Al-Shammari, A., Amsler, L., Sheridan, K., Nilsen, A., Streblow, D. N. & DeFilippis, V. R., 2015, In : PLoS Pathogens. 11, 12, e1005324

Research output: Contribution to journalArticle

Interferon Regulatory Factor-3
Alphavirus
Antiviral Agents
Interferon Type I
Interferons
18 Citations

Erratum: Functionally defined therapeutic targets in diffuse intrinsic pontine glioma(Nature Medicine (2015) 21 (555-559) DOI: 10.1038/nm.3855)

Grasso, C. S. , Tang, Y. , Truffaux, N. , Berlow, N. E. , Liu, L. , Debily, M. A. , Quist, M. J. , Davis, L. E. , Huang, E. C. , Woo, P. J. , Ponnuswami, A. , Chen, S. , Johung, T. B. , Sun, W. , Kogiso, M. , Du, Y. , Qi, L. , Huang, Y. , Hütt-Cabezas, M. , Warren, K. E. & 20 others Le Dret, L., Meltzer, P. S., Mao, H., Quezado, M., Van Vuurden, D. G., Abraham, J., Fouladi, M., Svalina, M. N., Wang, N., Hawkins, C., Nazarian, J., Alonso, M. M., Raabe, E. H., Hulleman, E., Spellman, P. T., Li, X. N., Keller, C., Pal, R., Grill, J. & Monje, M., Jul 7 2015, In : Nature Medicine. 21, 7, p. 827 1 p.

Research output: Contribution to journalArticle