Jessica Castle

Associate Professor

  • 1278 Citations
  • 21 h-Index
20092020

Research output per year

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Research Output

2020

An artificial intelligence decision support system for the management of type 1 diabetes

Tyler, N. S., Mosquera-Lopez, C. M., Wilson, L. M., Dodier, R. H., Branigan, D. L., Gabo, V. B., Guillot, F. H., Hilts, W. W., El Youssef, J., Castle, J. R. & Jacobs, P. G., Jul 1 2020, In : Nature Metabolism. 2, 7, p. 612-619 8 p.

Research output: Contribution to journalArticle

Open Access

Measuring glucose at the site of insulin delivery with a redox-mediated sensor

Jacobs, P. G., Tyler, N. S., Vanderwerf, S. M., Mosquera-Lopez, C., Seidl, T., Cargill, R., Branigan, D., Ramsey, K., Morris, K., Benware, S., Ward, W. K. & Castle, J. R., Oct 1 2020, In : Biosensors and Bioelectronics. 165, 112221.

Research output: Contribution to journalArticle

Reliability of the Dexcom G6 Continuous Glucose Monitor during Hyperbaric Oxygen Exposure

Huang, E., Demirel, S., Bliss, C., Savaser, D. & Castle, J. R., May 1 2020, In : Diabetes Technology and Therapeutics. 22, 5, p. 360-366 7 p.

Research output: Contribution to journalArticle

Open Access
2019

Adaptive tuning of basal and bolus insulin to reduce postprandial hypoglycemia in a hybrid artificial pancreas

Resalat, N., El Youssef, J., Reddy, R., Castle, J. & Jacobs, P., Aug 1 2019, In : Journal of Process Control. 80, p. 247-254 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
Open Access
5 Scopus citations

How Well Do Continuous Glucose Monitoring Systems Perform during Exercise?

Castle, J. R. & Rodbard, D., Jun 2019, In : Diabetes Technology and Therapeutics. 21, 6, p. 305-309 5 p.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Long-Term Safety and Tolerability of Dasiglucagon, a Stable-in-Solution Glucagon Analogue

Castle, J. & Elander, M., Feb 1 2019, In : Diabetes Technology and Therapeutics. 21, 2, p. 94-96 3 p.

Research output: Contribution to journalLetter

4 Scopus citations

Patient Input for Design of a Decision Support Smartphone Application for Type 1 Diabetes

Wilson, L. M., Tyler, N., Jacobs, P., Gabo, V., Senf, B., Reddy, R. & Castle, J., Jan 1 2019, (Accepted/In press) In : Journal of Diabetes Science and Technology.

Research output: Contribution to journalArticle

1 Scopus citations

Prediction of Hypoglycemia During Aerobic Exercise in Adults With Type 1 Diabetes

Reddy, R., Resalat, N., Wilson, L. M., Castle, J. R., El Youssef, J. & Jacobs, P. G., Sep 1 2019, In : Journal of Diabetes Science and Technology. 13, 5, p. 919-927 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
2018

Accuracy of wrist-worn activity monitors during common daily physical activities and types of structured exercise: Evaluation study

Kondama Reddy, R., Pooni, R., Zaharieva, D. P., Senf, B., El Youssef, J., Dassau, E., Doyle, F. J., Clements, M. A., Rickels, M. R., Patton, S. R., Castle, J. R., Riddell, M. C. & Jacobs, P. G., Dec 2018, In : JMIR mHealth and uHealth. 6, 12, e10338.

Research output: Contribution to journalArticle

13 Scopus citations

Control of Postprandial Hyperglycemia in Type 1 Diabetes by 24-Hour Fixed-Dose Coadministration of Pramlintide and Regular Human Insulin: A Randomized, Two-Way Crossover Study

Riddle, M. C., Nahra, R., Han, J., Castle, J., Hanavan, K., Hompesch, M., Huffman, D., Strange, P. & Öhman, P., Nov 1 2018, In : Diabetes Care. 41, 11, p. 2346-2352 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effect of Aerobic and Resistance Exercise on Glycemic Control in Adults With Type 1 Diabetes

Reddy, R., Wittenberg, A., Castle, J., El Youssef, J., Winters-Stone, K., Gillingham, M. & Jacobs, P., Jan 1 2018, (Accepted/In press) In : Canadian Journal of Diabetes.

Research output: Contribution to journalArticle

3 Scopus citations

Is Mini-Dose Glucagon the Answer to Preventing Exercise-Related Dysglycemia?

Castle, J., Sep 1 2018, In : Diabetes Care. 41, 9, p. 1842-1843 2 p.

Research output: Contribution to journalComment/debate

Randomized outpatient trial of single- and dual-hormone closed-loop systems that adapt to exercise using wearable sensors

Castle, J. R., Youssef, J. E., Wilson, L. M., Reddy, R., Resalat, N., Branigan, D., Ramsey, K., Leitschuh, J., Rajhbeharrysingh, U., Senf, B., Sugerman, S. M., Gabo, V. & Jacobs, P. G., Jul 1 2018, In : Diabetes care. 41, 7, p. 1471-1477 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Stable Liquid Glucagon: Beyond Emergency Hypoglycemia Rescue

Wilson, L. M. & Castle, J., Feb 1 2018, (Accepted/In press) In : Journal of diabetes science and technology.

Research output: Contribution to journalArticle

15 Scopus citations

The effect of exercise on sleep in adults with type 1 diabetes

Reddy, R., El Youssef, J., Winters-Stone, K., Branigan, D., Leitschuh, J., Castle, J. & Jacobs, P., Feb 1 2018, In : Diabetes, Obesity and Metabolism. 20, 2, p. 443-447 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

Advances in Subcutaneous Glucose Sensing

Castle, J., Aug 1 2017, In : Diabetes Technology and Therapeutics. 19, 8, p. 441-442 2 p.

Research output: Contribution to journalComment/debate

An Amperometric Glucose Sensor Integrated into an Insulin Delivery Cannula: In Vitro and in Vivo Evaluation

Ward, W. K., Heinrich, G., Breen, M., Benware, S., Vollum, N., Morris, K., Knutsen, C., Kowalski, J. D., Campbell, S., Biehler, J., Vreeke, M. S., Vanderwerf, S. M., Castle, J. & Cargill, R. S., Apr 1 2017, In : Diabetes Technology and Therapeutics. 19, 4, p. 226-236 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
37 Scopus citations

Future of automated insulin delivery systems

Castle, J. R., DeVries, J. H. & Kovatchev, B., Jun 2017, In : Diabetes Technology and Therapeutics. 19, p. S67-S72

Research output: Contribution to journalArticle

20 Scopus citations

Modeling Glucagon Action in Patients with Type 1 Diabetes

Emami, A., El Youssef, J., Rabasa-Lhoret, R., Pineau, J., Castle, J. & Haidar, A., Jul 1 2017, In : IEEE Journal of Biomedical and Health Informatics. 21, 4, p. 1163-1171 9 p., 7517341.

Research output: Contribution to journalArticle

2 Scopus citations
1 Scopus citations
2016

Comparative pharmacokinetic/pharmacodynamic study of liquid stable glucagon versus lyophilized glucagon in type 1 diabetes subjects

Castle, J., El Youssef, J., Branigan, D., Newswanger, B., Strange, P., Cummins, M., Shi, L. & Prestrelski, S., 2016, In : Journal of diabetes science and technology. 10, 5, p. 1101-1107 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Nonadjunctive use of continuous glucose monitoring for diabetes treatment decisions

Castle, J. & Jacobs, P., 2016, In : Journal of diabetes science and technology. 10, 5, p. 1169-1173 5 p.

Research output: Contribution to journalReview article

32 Scopus citations

Outcome measures for artificial pancreas clinical trials: A consensus report

Maahs, D. M., Buckingham, B. A., Castle, J. R., Cinar, A., Damiano, E. R., Dassau, E., Hans De Vries, J., Doyle, F. J., Griffen, S. C., Haidar, A., Heinemann, L., Hovorka, R., Jones, T. W., Kollman, C., Kovatchev, B., Levy, B. L., Nimri, R., O'Neal, D. N., Philip, M., Renard, E. & 4 others, Russell, S. J., Weinzimer, S. A., Zisser, H. & Lum, J. W., Jul 1 2016, In : Diabetes care. 39, 7, p. 1175-1179 5 p.

Research output: Contribution to journalArticle

115 Scopus citations

Randomized trial of a dual-hormone artificial pancreas with dosing adjustment during exercise compared with no adjustment and sensor-augmented pump therapy

Jacobs, P., El Youssef, J., Reddy, R., Resalat, N., Branigan, D., Condon, J., Preiser, N., Ramsey, K., Jones, M., Edwards, C., Kuehl, K., Leitschuh, J., Rajhbeharrysingh, U. & Castle, J., 2016, (Accepted/In press) In : Diabetes, Obesity and Metabolism.

Research output: Contribution to journalArticle

58 Scopus citations
2015

A novel, stable, aqueous Glucagon formulation using Ferulic acid as an Excipient

Bakhtiani, P. A., Caputo, N., Castle, J. R., Youssef, J. E., Carroll, J. M., David, L. L., Roberts, C. T. & Kenneth, W., Jan 1 2015, In : Journal of Diabetes Science and Technology. 9, 1, p. 17-23 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Development of a highly stable, nonaqueous glucagon formulation for delivery via infusion pump systems

Newswanger, B., Ammons, S., Phadnis, N., Kenneth Ward, W., Castle, J., Campbell, R. W. & Prestrelski, S. J., Jan 1 2015, In : Journal of Diabetes Science and Technology. 9, 1, p. 24-33 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Effect of repeated glucagon doses on hepatic glycogen in type 1 Diabetes: Implications for a bihormonal Closed-Loop system

Castle, J. R., Youssef, J. E., Bakhtiani, P. A., Cai, Y., Stobbe, J. M., Branigan, D., Ramsey, K., Jacobs, P., Reddy, R., Woods, M. & Ward, W. K., Nov 2015, In : Diabetes care. 38, 11, p. 2115-2119 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Fabrication of a flexible amperometric glucose sensor using additive processes

Du, X., Durgan, C. J., Matthews, D. J., Motley, J. R., Tan, X., Pholsena, K., Árnadoóttir, L., Castle, J. R., Jacobs, P. G., Cargill, R. S., Ward, W. K., Conley, J. F. & Herman, G. S., Jan 1 2015, In : ECS Journal of Solid State Science and Technology. 4, 4, p. P3069-P3074

Research output: Contribution to journalArticle

18 Scopus citations

Factors affecting the success of glucagon delivered during an automated closed-loop system in type 1 diabetes

Bakhtiani, P. A., El Youssef, J., Duell, A. K., Branigan, D. L., Jacobs, P. G., Lasarev, M. R., Castle, J. R. & Ward, W. K., Jan 1 2015, In : Journal of Diabetes and Its Complications. 29, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Incorporating an exercise detection, grading, and hormone dosing algorithm into the artificial pancreas using accelerometry and heart rate

Jacobs, P., Resalat, N., El Youssef, J., Reddy, R., Branigan, D., Preiser, N., Condon, J. & Castle, J., Nov 1 2015, In : Journal of diabetes science and technology. 9, 6, p. 1175-1184 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Is glucagon needed in type 1 diabetes?

Castle, J. R., Aug 1 2015, In : The Lancet Diabetes and Endocrinology. 3, 8, p. 578-579 2 p.

Research output: Contribution to journalComment/debate

5 Scopus citations
2014

Automated control of an adaptive bihormonal, dual-sensor artificial pancreas and evaluation during inpatient studies

Jacobs, P. G., El Youssef, J., Castle, J., Bakhtiani, P., Branigan, D., Breen, M., Bauer, D., Preiser, N., Leonard, G., Stonex, T. & Ward, W. K., Oct 1 2014, In : IEEE Transactions on Biomedical Engineering. 61, 10, p. 2569-2581 13 p., 6814769.

Research output: Contribution to journalArticle

53 Scopus citations

Biochemical stabilization of glucagon at alkaline pH

Caputo, N., Jackson, M. A., Castle, J. R., El Youssef, J., Bakhtiani, P. A., Bergstrom, C. P., Carroll, J. M., Breen, M. E., Leonard, G. L., David, L. L., Roberts, C. T. & Ward, W. K., Jan 1 2014, In : Diabetes Technology and Therapeutics. 16, 11, p. 747-758 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Can glucose be monitored accurately at the site of subcutaneous insulin delivery?

Ward, W. K., Castle, J. R., Jacobs, P. G. & Cargill, R. S., May 2014, In : Journal of Diabetes Science and Technology. 8, 3, p. 568-574 7 p.

Research output: Contribution to journalReview article

8 Scopus citations

Modeling the glucose sensor error

Facchinetti, A., Del Favero, S., Sparacino, G., Castle, J. R., Ward, W. K. & Cobelli, C., Mar 1 2014, In : IEEE Transactions on Biomedical Engineering. 61, 3, p. 620-629 10 p., 6615958.

Research output: Contribution to journalArticle

79 Scopus citations

Quantification of the glycemic response to microdoses of subcutaneous glucagon at varying insulin levels

El Youssef, J., Castle, J. R., Bakhtiani, P. A., Haidar, A., Branigan, D. L., Breen, M. & Ward, W. K., Nov 1 2014, In : Diabetes care. 37, 11, p. 3054-3060 7 p.

Research output: Contribution to journalArticle

32 Scopus citations
2013

A review of artificial pancreas technologies with an emphasis on bi-hormonal therapy

Bakhtiani, P. A., Zhao, L. M., El Youssef, J., Castle, J. R. & Ward, W. K., Dec 2013, In : Diabetes, Obesity and Metabolism. 15, 12, p. 1065-1070 6 p.

Research output: Contribution to journalReview article

49 Scopus citations

Digital patterning of glucose oxidase for electrochemical glucose biosensors

Herman, G. S., Durgan, C., Du, X., Arnadottir, L., Matthews, D., Klan, T., Kundu, S., Conley, J. F., Ward, K., Cargill, R., Castle, J. & Jacobs, P., Dec 1 2013, NIP 2013: 29th International Conference on Digital Printing Technologies and Digital Fabrication 2013. 1 p. (International Conference on Digital Printing Technologies).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mechanisms of glucagon degradation at alkaline pH

Caputo, N., Castle, J. R., Bergstrom, C. P., Carroll, J. M., Bakhtiani, P. A., Jackson, M. A., Roberts, C. T., David, L. L. & Ward, W. K., Jun 19 2013, In : Peptides. 45, p. 40-47 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
2012

Discomfort from an alkaline formulation delivered subcutaneously in humans: Albumin at pH 7 versus pH 10

Ward, W. K., Castle, J. R., Branigan, D. L., Massoud, R. G. & El Youssef, J., Jun 14 2012, In : Clinical Drug Investigation. 32, 7, p. 433-438 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Stable liquid glucagon formulations for rescue treatment and bi-hormonal closed-loop pancreas

Jackson, M. A., Caputo, N., Castle, J. R., David, L. L., Roberts, C. T. & Ward, W. K., Dec 1 2012, In : Current diabetes reports. 12, 6, p. 705-710 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

The accuracy benefit of multiple amperometric glucose sensors in people with type 1 diabetes

Castle, J. R., Pitts, A., Hanavan, K., Muhly, R., El Youssef, J., Hughes-Karvetski, C., Kovatchev, B. & Ward, W. K., Apr 1 2012, In : Diabetes care. 35, 4, p. 706-710 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

The effect of rising vs. falling glucose level on amperometric glucose sensor lag and accuracy in Type1 diabetes

Ward, W. K., Engle, J. M., Branigan, D., El Youssef, J., Massoud, R. G. & Castle, J. R., Aug 1 2012, In : Diabetic Medicine. 29, 8, p. 1067-1073 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
2011

A controlled study of the effectiveness of an adaptive closed-loop algorithm to minimize corticosteroid-induced stress hyperglycemia in type 1 diabetes

El Youssef, J., Castle, J. R., Branigan, D. L., Massoud, R. G., Breen, M. E., Jacobs, P. G., Bequette, B. W. & Ward, W. K., Nov 2011, In : Journal of Diabetes Science and Technology. 5, 6, p. 1312-1326 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

Development of a fully automated closed loop artificial pancreas control system with dual pump delivery of insulin and glucagon

Jacobs, P. G., Youssef, J. E., Castle, J. R., Engle, J. M., Branigan, D. L., Johnson, P., Massoud, R., Kamath, A. & Ward, W. K., Dec 26 2011, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. p. 397-400 4 p. 6090127. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Scopus citations
27 Scopus citations