Jeffrey Kaye

Professor

  • 28389 Citations
  • 87 h-Index
1976 …2020
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Research Output 1986 2019

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Article
1998
505 Citations (Scopus)

The efficacy of Ginkgo biloba on cognitive function in Alzheimer disease

Oken, B., Storzbach, D. M. & Kaye, J., Nov 1998, In : Archives of Neurology. 55, 11, p. 1409-1415 7 p.

Research output: Contribution to journalArticle

Ginkgo biloba
Cognition
Alzheimer Disease
Dementia
Meta-Analysis
24 Citations (Scopus)
Alzheimer Disease
Cognition
Longitudinal Studies
Dementia
Disease Progression
107 Citations (Scopus)

Verbal fluency task affects gait in Parkinson's disease with motor freezing

Camicioli, R., Oken, B., Sexton, G., Kaye, J. & Nutt, J., 1998, In : Journal of Geriatric Psychiatry and Neurology. 11, 4, p. 181-185 5 p.

Research output: Contribution to journalArticle

Gait
Freezing
Parkinson Disease
Walking
Antiparkinson Agents
1997
49 Citations (Scopus)

A prospective study of cognitive health in the elderly (Oregon Brain Aging Study): Effects of family history and apolipoprotein E genotype

Payami, H., Grimslid, H., Oken, B., Camicioli, R., Sexton, G., Dame, A., Howieson, D. & Kaye, J., Apr 1997, In : American Journal of Human Genetics. 60, 4, p. 948-956 9 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Dementia
Genotype
Prospective Studies
Health
99 Citations (Scopus)

Balance in the healthy elderly: Posturography and clinical assessment

Camicioli, R., Panzer, V. P. & Kaye, J., 1997, In : Archives of Neurology. 54, 8, p. 976-981 6 p.

Research output: Contribution to journalArticle

Gait
Geriatrics
Longitudinal Studies
Leg
Health
171 Citations (Scopus)

Cognitive markers preceding Alzheimer's dementia in the healthy oldest old

Hoiuieson, D. B., Dame, A., Camicioli, R., Sexton, G., Payami, H. & Kaye, J., May 1997, In : Journal of the American Geriatrics Society. 45, 5, p. 584-589 6 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Volunteers
Independent Living
Neuropsychological Tests
71 Citations (Scopus)

Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease

Payami, H., Schellenberg, G. D., Zareparsi, S., Kaye, J., Sexton, G. J., Head, M. A., Matsuyama, S. S., Jarvik, L. F., Miller, B., McManus, D. Q., Bird, T. D., Katzman, R., Heston, L., Norman, D. & Small, G. W., Aug 1997, In : Neurology. 49, 2, p. 512-518 7 p.

Research output: Contribution to journalArticle

HLA-A2 Antigen
Age of Onset
varespladib methyl
Alzheimer Disease
Alleles

In reply

Janowsky, J. S., Kaye, J. & Carper, R. A., 1997, In : Journal of the American Geriatrics Society. 45, 6, p. 778 1 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Modulation of the age at onset of Parkinson's disease by apolipoprotein E genotypes

Zareparsi, S., Kaye, J., Camicioli, R., Grimslid, H., Oken, B., Litt, M., Nutt, J., Bird, T., Schellenberg, G. & Payami, H., Oct 1997, In : Annals of Neurology. 42, 4, p. 655-658 4 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Genotype
Parkinson Disease
Alzheimer Disease
Apolipoprotein E4
1 Citation (Scopus)

Neocortical temporal lobe sclerosis masquerading as Alzheimer dementia: Does herpes virus encephalopathy protect against Alzheimer's disease?

Ball, M. J., Kaye, J. & Steiner, I., Jan 1997, In : Clinical Neuropathology. 16, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Brain Diseases
Sclerosis
Temporal Lobe
Alzheimer Disease
Viruses
16 Citations (Scopus)

Oldest-old healthy brain function: The genomic potentials

Kaye, J., Oct 1997, In : Archives of Neurology. 54, 10, p. 1217-1221 5 p.

Research output: Contribution to journalArticle

Dementia
Brain
Nervous System
Genes
Alzheimer Disease
73 Citations (Scopus)

Sex differences in the corpus callosum with aging

Salat, D., Ward, A., Kaye, J. & Janowsky, J. S., Mar 1997, In : Neurobiology of Aging. 18, 2, p. 191-197 7 p.

Research output: Contribution to journalArticle

Corpus Callosum
Sex Characteristics
Atrophy
Pons
Cerebellum
239 Citations (Scopus)

Talking while walking: The effect of a dual task in aging and Alzheimer's disease

Camicioli, R., Howieson, D., Lehman, S. & Kaye, J., Apr 1997, In : Neurology. 48, 4, p. 955-958 4 p.

Research output: Contribution to journalArticle

Walking
Alzheimer Disease
Independent Living
Parkinsonian Disorders
Gait
331 Citations (Scopus)

Volume loss of the hippocampus and temporal lobe in healthy elderly persons destined to develop dementia

Kaye, J., Swihart, T., Howieson, D., Dame, A., Moore, M. M., Karnos, T., Camicioli, R., Ball, M., Oken, B. & Sexton, G., May 1997, In : Neurology. 48, 5, p. 1297-1304 8 p.

Research output: Contribution to journalArticle

Temporal Lobe
Dementia
Hippocampus
Atrophy
Neurofibrillary Tangles
1996
16 Citations (Scopus)

Asymmetrical memory decline in normal aging and dementia

Janowsky, J. S., Carper, R. A. & Kaye, J., Jun 1996, In : Neuropsychologia. 34, 6, p. 527-535 9 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
97 Citations (Scopus)

Atrophy of the corpus callosum in Alzheimer's disease versus healthy aging

Janowsky, J. S., Kaye, J. & Carper, R. A., Jul 1996, In : Journal of the American Geriatrics Society. 44, 7, p. 798-803 6 p.

Research output: Contribution to journalArticle

Corpus Callosum
Atrophy
Alzheimer Disease
Healthy Volunteers
Dementia
189 Citations (Scopus)

Gender difference in apolipoprotein E - associated risk for familial alzheimer disease: A possible clue to the higher incidence of alzheimer disease in women

Payami, H., Zareparsi, S., Montee, K. R., Sexton, G. J., Kaye, J., Bird, T. D., Yu, C. E., Wijsman, E. M., Heston, L. L., Litt, M. & Schellenberg, G. D., 1996, In : American Journal of Human Genetics. 58, 4, p. 803-811 9 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Alzheimer Disease
Heterozygote
Incidence
Genotype
29 Citations (Scopus)

Increased risk of familial late-onset Alzheimer's disease in women

Payami, H., Montee, K., Grimslid, H., Shattuc, S. & Kaye, J., Jan 1996, In : Neurology. 46, 1, p. 126-129 4 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Odds Ratio
Alzheimer disease type 2
1995
8 Citations (Scopus)

Cognitive function and activities of daily living in severely impaired dementia patients

Wild, K. & Kaye, J., 1995, In : Clinical Gerontologist. 15, 3, p. 3-16 14 p.

Research output: Contribution to journalArticle

Activities of Daily Living
dementia
Cognition
Dementia
Aptitude
57 Citations (Scopus)

Genetic anticipation in parkinson's disease

Payami, H., Bernard, S., Larsen, K., Kaye, J. & Nutt, J., 1995, In : Neurology. 45, 1, p. 135-138 4 p.

Research output: Contribution to journalArticle

Genetic Anticipation
Age of Onset
Parkinson Disease
Trinucleotide Repeats
Onset
2 Citations (Scopus)

The Apolipoprotein E E4 Allele and Sex-Specific Risk of Alzheimer's Disease-Reply

Payami, H., Montee, K. R., Kaye, J., Wijsman, E. M., Bird, T., Yu, C. E., Heston, L. L. & Schellenberg, G. D., Feb 1 1995, In : JAMA - Journal of the American Medical Association. 273, 5, p. 374 1 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Apolipoproteins E
Alzheimer Disease
Alleles
1994
21 Citations (Scopus)
Task Performance and Analysis
Reaction Time
95 Citations (Scopus)

Alzheimer's Disease, Apolipoprotein E4, and Gender

Payami, H., Montee, K. R., Kaye, J., Bird, T. D., Yu, C. E., Wijsman, E. M. & Schellenberg, G. D., May 4 1994, In : JAMA - Journal of the American Medical Association. 271, 17, p. 1316-1317 2 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Sex Factors
Apolipoproteins E
Alzheimer Disease
47 Citations (Scopus)

Attention deficit in alzheimer’s disease is not simulated by an anticholinergic/antihistaminergic drug and is distinct from deficits in healthy aging

Oken, B., Kishiyama, S. S., Kaye, J. & Howieson, D., 1994, In : Neurology. 44, 4, p. 657-662 6 p.

Research output: Contribution to journalArticle

Cholinergic Antagonists
Alzheimer Disease
Cues
Diphenhydramine
Pharmaceutical Preparations
55 Citations (Scopus)

Brain N-acetyl-l-aspartic acid in Alzheimer's disease: a proton magnetic resonance spectroscopy study

Kwo-On-Yuen, P. F., Newmark, R. D., Budinger, T. F., Kaye, J., Ball, M. J. & Jagust, W. J., Dec 26 1994, In : Brain Research. 667, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

Aspartic Acid
Alzheimer Disease
Dementia
Brain
Parahippocampal Gyrus
23 Citations (Scopus)

Early noncognitive change in Alzheimer's disease and healthy aging

Wild, K., Kaye, J. & Oken, B., 1994, In : Journal of Geriatric Psychiatry and Neurology. 7, 4, p. 199-205 7 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Equipment and Supplies
Caregivers
Personality
18 Citations (Scopus)

Evidence for familial factors that protect against dementia and outweigh the effect of increasing age

Payami, H., Montee, K. & Kaye, J., 1994, In : American Journal of Human Genetics. 54, 4, p. 650-657 8 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Siblings
Parents
Genetic Counseling
1 Citation (Scopus)

Genetic factors that protect against dementia [6]

Hirst, C., Yee, I. M. L., Sadovnick, A. D., Payami, H., Montee, K. & Kaye, J., 1994, In : American Journal of Human Genetics. 55, 3, p. 588-589 2 p.

Research output: Contribution to journalArticle

Life Tables
Family Health
Age Factors
Age of Onset
Canada
122 Citations (Scopus)

Neurologic Evaluation of the Optimally Healthy Oldest Old

Kaye, J., Oken, B., Howieson, D., Howieson, J., Holm, L. A. & Dennison, K., 1994, In : Archives of Neurology. 51, 12, p. 1205-1211 7 p.

Research output: Contribution to journalArticle

Smell
Nervous System
Neurologic Manifestations
Stereognosis
Intelligence Tests
81 Citations (Scopus)

The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease

Yu, C. E., Payami, H., Olson, J. M., Boehnke, M., Wijsman, E. M., Orr, H. T., Kukull, W. A., Goddard, K. A. B., Nemens, E., White, J. A., Alonso, M. E., Taylor, T. D., Ball, M. J., Kaye, J., Morris, J., Chui, H., Sadovnick, A. D., Martin, G. M., Larson, E. B., Heston, L. L. & 2 others, Bird, T. D. & Schellenberg, G. D., 1994, In : American Journal of Human Genetics. 54, 4, p. 631-642 12 p.

Research output: Contribution to journalArticle

Phentolamine
Apolipoproteins E
Multigene Family
Alzheimer Disease
Gene Frequency
1993
273 Citations (Scopus)

Apolipoprotein E genotype and Alzheimer's disease

Noguchi, S., Murakami, K., Yamada, N., Payami, H., Kaye, J., Heston, L. L., Bird, T. D. & Schellenberg, G. D., Sep 18 1993, In : The Lancet. 342, 8873, p. 737-738 2 p.

Research output: Contribution to journalArticle

Multi-Infarct Dementia
Amyloid beta-Protein Precursor
Age Factors
Apolipoproteins E
Genetic Markers
79 Citations (Scopus)

Apolipoprotein E genotype and Alzheimer's disease.

Payami, H., Kaye, J., Heston, L. L., Bird, T. D. & Schellenberg, G. D., Sep 18 1993, In : Lancet. 342, 8873, p. 738 1 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Gene Frequency
Alzheimer Disease
Alleles
Odds Ratio
57 Citations (Scopus)

Chromosome 14 and late-onset Familial Alzheimer Disease (FAD)

Schellenberg, G. D., Payami, H., Wijsman, E. M., Orr, H. T., Goddard, K. A. B., Anderson, L., Nemens, E., White, J. A., Alonso, M. E., Ball, M. J., Kaye, J., Morris, J. C., Chui, H., Sadovnick, A. D., Heston, L. L., Martin, G. M. & Bird, T. D., Sep 1993, In : American Journal of Human Genetics. 53, 3, p. 619-628 10 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 14
Alzheimer Disease
Age of Onset
Penetrance
Pedigree
10 Citations (Scopus)

Interuncal distance: Marker of aging and Alzheimer disease

Howieson, J., Kaye, J., Holm, L. & Howieson, D., 1993, In : American Journal of Neuroradiology. 14, 3, p. 647-650 4 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Atrophy
Dementia
Healthy Volunteers
Research Design
114 Citations (Scopus)

Neurologic function in the optimally healthy oldest old: Neuropsychological evaluation

Howieson, D., Holm, L. A., Kaye, J., Oken, B. & Howieson, J., Oct 1993, In : Neurology. 43, 10, p. 1882-1886 5 p.

Research output: Contribution to journalArticle

Cognition
Nervous System
Independent Living
Neuropsychological Tests
Healthy Volunteers
38 Citations (Scopus)

Reductions in parietal and temporal cerebral metabolic rates for glucose are not specific for Alzheimer's disease

Schapiro, M. B., Pietrini, P., Grady, C. L., Ball, M. J., DeCarli, C., Kumar, A., Kaye, J. & Haxby, J. V., 1993, In : Journal of Neurology, Neurosurgery and Psychiatry. 56, 8, p. 859-864 6 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Glucose
Parkinson Disease
Dementia
Parietal Lobe
1992
56 Citations (Scopus)

Electrophysiologic function in the healthy, extremely old

Oken, B. & Kaye, J., 1992, In : Neurology. 42, 3, p. 519-526 8 p.

Research output: Contribution to journalArticle

Electroencephalography
Auditory Evoked Potentials
Cognition
Healthy Volunteers
Blood Pressure
205 Citations (Scopus)

Linkage and mutational analysis of familial Alzheimer disease kindreds for the APP gene region

Kamino, K., Orr, H. T., Payami, H., Wijsman, E. M., Alonso, M. E., Pulst, S. M., Anderson, L., O'Dahl, S., Nemens, E., White, J. A., Sadovnick, A. D., Ball, M. J., Kaye, J., Warren, A., McInnis, M., Antonarakis, S. E., Korenberg, J. R., Sharma, V., Kukull, W., Larson, E. & 4 others, Heston, L. L., Martin, G. M., Bird, T. D. & Schellenberg, G. D., Nov 1992, In : American Journal of Human Genetics. 51, 5, p. 998-1014 17 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Alzheimer Disease
Codon
Genes
Mutation
70 Citations (Scopus)

The significance of age-related enlargement of the cerebral ventricles in healthy men and women measured by quantitative computed X-ray tomography

Kaye, J., DeCarli, C., Luxenberg, J. S. & Rapoport, S. I., 1992, In : Journal of the American Geriatrics Society. 40, 3, p. 225-231 7 p.

Research output: Contribution to journalArticle

Cerebral Ventricles
X Ray Computed Tomography
Atrophy
Cognition
Third Ventricle
1991
32 Citations (Scopus)

HLA-A2, or a closely linked gene, confers susceptibility to early-onset sporadic alzheimer’s disease in mene

Payami, H., Kaye, J., Becker, W., Norman, D. & Wetzsteon, P., 1991, In : Neurology. 41, 10, p. 1544-1548 5 p.

Research output: Contribution to journalArticle

HLA-A2 Antigen
varespladib methyl
Alzheimer Disease
Genes
Histocompatibility Antigens
1990
9 Citations (Scopus)

Cerebrospinal fluid gradients of acetylcholinesterase and butyrylcholinesterase activity in healthy aging

Atack, J. R., May, C., Kaye, J. & Rapoport, S. I., 1990, In : Neurochemistry International. 16, 4, p. 533-538 6 p.

Research output: Contribution to journalArticle

Butyrylcholinesterase
Acetylcholinesterase
Cerebrospinal Fluid
Homovanillic Acid
Spinal Cord
179 Citations (Scopus)

Cerebrospinal fluid production is reduced in healthy aging

May, C., Kaye, J., Atack, J. R., Schapiro, M. B., Friedland, R. P. & Rapoport, S. I., 1990, In : Neurology. 40, 3, p. 500-503 4 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Cerebrospinal Fluid Proteins
Proteins
Protein
Dilatation
126 Citations (Scopus)

Critical analysis of the use of computer-assisted transverse axial tomography to study human brain in aging and dementia of the alzheirner type

DeCarli, C., Kaye, J., Horwitz, B. & Rapoport, S. I., 1990, In : Neurology. 40, 6, p. 872-883 12 p.

Research output: Contribution to journalArticle

X Ray Computed Tomography
Dementia
Autopsy
Alzheimer Disease
Tomography
24 Citations (Scopus)

Plasticity in the Aging Brain: Reversibility of Anatomic, Metabolic, and Cognitive Deficits in Normal-Pressure Hydrocephalus Following Shunt Surgery

Kaye, J., Grady, C. L., Haxby, J. V., Moore, A. & Friedland, R. P., 1990, In : Archives of Neurology. 47, 12, p. 1336-1341 6 p.

Research output: Contribution to journalArticle

Normal Pressure Hydrocephalus
Brain
Glucose
Positron-Emission Tomography
Neuropsychological Tests
1989
50 Citations (Scopus)

Serial quantitative ct analysis of brain morphometrics in adult down’s syndrome at different ages

Schapiro, M. B., Luxenberg, J. S., Kaye, J., Haxby, J. V., Friedland, R. P. & Rapoport, S. I., 1989, In : Neurology. 39, 10, p. 1349-1353 5 p.

Research output: Contribution to journalArticle

Down Syndrome
Atrophy
Dementia
Brain
Alzheimer Disease
1988
54 Citations (Scopus)

Cerebrospinal fluid cholinesterases in aging and in dementia of the Alzheimer type

Atack, J. R., May, C., Kaye, J., Kay, A. D. & Rapoport, S. I., 1988, In : Annals of Neurology. 23, 2, p. 161-167 7 p.

Research output: Contribution to journalArticle

Cholinesterases
Acetylcholinesterase
Cerebrospinal Fluid
Alzheimer Disease
Butyrylcholinesterase
32 Citations (Scopus)

Cerebrospinal fluid monoamine markers are decreased in dementia of the Alzheimer type with extrapyramidal features

Kaye, J., May, C., Daly, E., Atack, J. R., Sweeney, D. J., Luxenberg, J. S., Kay, A. D., Kaufman, S., Milstien, S., Friedland, R. P. & Rapoport, S. I., 1988, In : Neurology. 38, 4, p. 554-557 4 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Alzheimer Disease
Biopterin
Homovanillic Acid
Dementia
38 Citations (Scopus)

Cerebrospinal fluid neurochemistry in the myoclonic subtype of Alzheimer's disease

Kaye, J., May, C., Atack, J. R., Daly, E., Sweeney, D. L., Beal, M. F., Kaufman, S., Milstien, S., Friedland, R. P. & Rapoport, S. I., 1988, In : Annals of Neurology. 24, 5, p. 647-650 4 p.

Research output: Contribution to journalArticle

Neurochemistry
Cerebrospinal Fluid
Alzheimer Disease
Myoclonus
Acetylcholinesterase
67 Citations (Scopus)

Cerebrospinal Fluid Somatostatin and Neuropeptide Y: Concentrations in Aging and in Dementia of the Alzheimer Type With and Without Extrapyramidal Signs

Atack, J. R., Beal, M. F., May, C., Kaye, J., Mazurek, M. F., Kay, A. D. & Rapoport, S. I., 1988, In : Archives of Neurology. 45, 3, p. 269-274 6 p.

Research output: Contribution to journalArticle

Neuropeptide Y
Somatostatin
Cerebrospinal Fluid
Alzheimer Disease
Healthy Volunteers
29 Citations (Scopus)

CSF α-MSH in dementia of the Alzheimer type

Rainero, I., May, C., Kaye, J., Friedland, R. P. & Rapoport, S. I., 1988, In : Neurology. 38, 8, p. 1281-1284 4 p.

Research output: Contribution to journalArticle

Melanocyte-Stimulating Hormones
Alzheimer Disease
Dementia
Homovanillic Acid
Age of Onset