Jeffrey Kaye

Professor

  • 28389 Citations
  • 87 h-Index
1976 …2020
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Research Output 1986 2019

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Article
2008
109 Citations (Scopus)

Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI

the Alzheimer’s Disease Cooperative Study (ADCS), Sep 1 2008, In : Neurobiology of Aging. 29, 9, p. 1285-1295 11 p.

Research output: Contribution to journalArticle

Vitamin E
Atrophy
Disease Progression
Entorhinal Cortex
Brain
57 Citations (Scopus)

Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels

Bekris, L. M., Millard, S. P., Galloway, N. M., Vuletic, S., Albers, J. J., Li, G., Galasko, D. R., DeCarli, C., Farlow, M. R., Clark, C. M., Quinn, J., Kaye, J., Schellenberg, G. D., Tsuang, D., Peskind, E. R. & Yu, C. E., 2008, In : Journal of Alzheimer's Disease. 13, 3, p. 255-266 12 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Single Nucleotide Polymorphism
Cerebrospinal Fluid
Genes
Proteins
210 Citations (Scopus)

Status of computerized cognitive testing in aging: A systematic review

Wild, K., Howieson, D., Webbe, F., Seelye, A. & Kaye, J., Nov 2008, In : Alzheimer's and Dementia. 4, 6, p. 428-437 10 p.

Research output: Contribution to journalArticle

Reproducibility of Results
Cognition
Psychometrics
Population
Reaction Time
95 Citations (Scopus)

Trajectories of brain loss in aging and the development of cognitive impairment

Carlson, N. E., Moore, M. M., Dame, A., Howieson, D., Silbert, L., Quinn, J. & Kaye, J., Mar 2008, In : Neurology. 70, 11, p. 828-833 6 p.

Research output: Contribution to journalArticle

Brain
Dementia
Cognitive Dysfunction
Atrophy
Healthy Volunteers
96 Citations (Scopus)

Trajectory of mild cognitive impairment onset

Howieson, D., Carlson, N. E., Moore, M. M., Wasserman, D., Abendroth, C. D., Payne-Murphy, J. & Kaye, J., Mar 2008, In : Journal of the International Neuropsychological Society. 14, 2, p. 192-198 7 p.

Research output: Contribution to journalArticle

Dementia
Independent Living
Cognitive Dysfunction
Age of Onset
20 Citations (Scopus)

Translational gene mapping of cognitive decline

Wilmot, B., McWeeney, S., Nixon, R. R., Montine, T. J., Laut, J., Harrington, C. C., Kaye, J. & Kramer, P. L., Apr 2008, In : Neurobiology of Aging. 29, 4, p. 524-541 18 p.

Research output: Contribution to journalArticle

Chromosome Mapping
Alzheimer Disease
Cognition
RNA
Genes
91 Citations (Scopus)

Unobtrusive assessment of activity patterns associated with mild cognitive impairment

Hayes, T. L., Abendroth, F., Adami, A., Pavel, M., Zitzelberger, T. A. & Kaye, J., Nov 2008, In : Alzheimer's and Dementia. 4, 6, p. 395-405 11 p.

Research output: Contribution to journalArticle

Wavelet Analysis
Nervous System
Cognitive Dysfunction
Walking Speed

xix-xxii

Qizilbash, N., Schneider, L. S., Chui, H., Tariot, P., Brodaty, H., Kaye, J. & Erkinjuntti, T., Jan 14 2008, In : Unknown Journal. p. 1-904 904 p.

Research output: Contribution to journalArticle

2007
5 Citations (Scopus)

A simple method to rule out dementia with temporal orientation

Tractenberg, R. E., Weiner, M. F., Aisen, P. S., Kaye, J. & Fuh, J. L., Jan 2007, In : Alzheimer's and Dementia. 3, 1, p. 28-32 5 p.

Research output: Contribution to journalArticle

Dementia
Cognition
Longitudinal Studies
Alzheimer Disease
Sensitivity and Specificity
181 Citations (Scopus)

Blood-brain barrier impairment in Alzheimer disease: Stability and functional significance

Bowman, G., Kaye, J., Moore, M., Waichunas, D., Carlson, N. E. & Quinn, J., May 2007, In : Neurology. 68, 21, p. 1809-1814 6 p.

Research output: Contribution to journalArticle

Blood-Brain Barrier
Albumins
Alzheimer Disease
Disease Progression
Immunoglobulin G
2 Citations (Scopus)

Brain volumes in Guam dementia vs Parkinson dementia complex vs aging Chamorro adults

Kaye, J., Moore, M. M., Galasko, D., Craig, U. K., Adonay, R. & Silbert, L., Jul 2007, In : Neurology. 69, 2, p. 196-199 4 p.

Research output: Contribution to journalArticle

Guam
Dementia
Brain
Neurodegenerative Diseases
Atrophy
749 Citations (Scopus)

Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

Ray, S., Britschgi, M., Herbert, C., Takeda-Uchimura, Y., Boxer, A., Blennow, K., Friedman, L. F., Galasko, D. R., Jutel, M., Karydas, A., Kaye, J., Leszek, J., Miller, B. L., Minthon, L., Quinn, J., Rabinovici, G. D., Robinson, W. H., Sabbagh, M. N., So, Y. T., Sparks, D. L. & 5 others, Tabaton, M., Tinklenberg, J., Yesavage, J. A., Tibshirani, R. & Wyss-Coray, T., Nov 2007, In : Nature Medicine. 13, 11, p. 1359-1362 4 p.

Research output: Contribution to journalArticle

Blood Proteins
Alzheimer Disease
Plasmas
Asymptomatic Diseases
Hematopoiesis
258 Citations (Scopus)

Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases

Nakashima-Yasuda, H., Uryu, K., Robinson, J., Xie, S. X., Hurtig, H., Duda, J. E., Arnold, S. E., Siderowf, A., Grossman, M., Leverenz, J. B., Woltjer, R. R., Lopez, O. L., Hamilton, R., Tsuang, D. W., Galasko, D., Masliah, E., Kaye, J., Clark, C. M., Montine, T. J., Lee, V. M. Y. & 1 others, Trojanowski, J. Q., Sep 2007, In : Acta Neuropathologica. 114, 3, p. 221-229 9 p.

Research output: Contribution to journalArticle

Lewy Body Disease
DNA-Binding Proteins
Morbidity
Dementia
Lewy Bodies
15 Citations (Scopus)
Medication Adherence
Alarm systems
Medical problems
Medication Systems
Monitoring
207 Citations (Scopus)

CSF tau/Aβ42 ratio for increased risk of mild cognitive impairment: A follow-up study

Li, G., Sokal, I., Quinn, J., Leverenz, J. B., Brodey, M., Schellenberg, G. D., Kaye, J., Raskind, M. A., Zhang, J., Peskind, E. R. & Montine, T. J., Aug 2007, In : Neurology. 69, 7, p. 631-639 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Odds Ratio
Dementia
Biomarkers
Prodromal Symptoms
61 Citations (Scopus)

Cycad exposure and risk of dementia, MCI, and PDC in the Chamorro population of Guam

Borenstein, A. R., Mortimer, J. A., Schofield, E., Wu, Y., Salmon, D. P., Gamst, A., Olichney, J., Thal, L. J., Silbert, L., Kaye, J., Craig, U. L., Schellenberg, G. D. & Galasko, D. R., May 2007, In : Neurology. 68, 21, p. 1764-1771 8 p.

Research output: Contribution to journalArticle

Guam
Parkinsonian Disorders
Dementia
Population
Odds Ratio
53 Citations (Scopus)

F2-isoprostanes as biomarkers of late-onset Alzheimer's disease

Montine, T. J., Quinn, J., Kaye, J. & Morrow, J. D., Sep 2007, In : Journal of Molecular Neuroscience. 33, 1, p. 114-119 6 p.

Research output: Contribution to journalArticle

F2-Isoprostanes
Biomarkers
Alzheimer Disease
Cerebrospinal Fluid
Dementia
68 Citations (Scopus)

Physical activity and the risk of dementia in oldest old

Sumic, A., Michael, Y. L., Carlson, N. E., Howieson, D. & Kaye, J., Apr 2007, In : Journal of Aging and Health. 19, 2, p. 242-259 18 p.

Research output: Contribution to journalArticle

dementia
Dementia
Exercise
Survival Analysis
old age
44 Citations (Scopus)

Prevalence of dementia in Chamorros on Guam: Relationship to age, gender, education, and APOE

Galasko, D., Salmon, D., Gamst, A., Olichney, J., Thal, L. J., Silbert, L., Kaye, J., Brooks, P., Adonay, R., Craig, U. K., Schellenberg, G. & Borenstein, A. R., May 2007, In : Neurology. 68, 21, p. 1772-1781 10 p.

Research output: Contribution to journalArticle

Guam
Dementia
Education
Parkinsonian Disorders
Vascular Dementia
242 Citations (Scopus)

The National Alzheimer's Coordinating Center (NACC) database: The uniform data set

Beekly, D. L., Ramos, E. M., Lee, W. W., Deitrich, W. D., Jacka, M. E., Wu, J., Hubbard, J. L., Koepsell, T. D., Morris, J. C., Kukull, W. A., Reiman, E. M., Kowall, N., Landreth, G., Shelanski, M., Welsh-Bohmer, K., Levey, A. I., Potter, H., Ghetti, B., Price, D., Hyman, B. & 20 others, Petersen, R. C., Sano, M., Ferris, S. H., Mesulam, M. M., Kaye, J., Bennett, D. A., Yesavage, J., Marson, D., Beck, C., DeCarli, C., Cotman, C., Cummings, J. L., Thal, L. J., Markesbery, W., Gilman, S., Trojanowski, J. Q., DeKosky, S. T., Chui, H., Rosenberg, R. & Raskind, M., Jul 2007, In : Alzheimer Disease and Associated Disorders. 21, 3, p. 249-258 10 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Databases
National Institute on Aging (U.S.)
Advisory Committees
Information Storage and Retrieval
83 Citations (Scopus)

Validity of the clinical dementia rating scale for the detection and staging of dementia in Brazilian patients

Fagundes Chaves, M. L., Camozzato, A. L., Godinho, C., Kochhann, R., Schuh, A., De Almeida, V. L. & Kaye, J., Jul 2007, In : Alzheimer Disease and Associated Disorders. 21, 3, p. 210-217 8 p.

Research output: Contribution to journalArticle

Dementia
National Institute of Neurological Disorders and Stroke
Diagnostic and Statistical Manual of Mental Disorders
Alzheimer Disease
Vascular Dementia
2006
84 Citations (Scopus)

ADCS Prevention Instrument Project: Assessment of instrumental activities of daily living for community-dwelling elderly individuals in dementia prevention clinical trials

Galasko, D., Bennett, D. A., Sano, M., Marson, D., Kaye, J. & Edland, S. D., Oct 2006, In : Alzheimer Disease and Associated Disorders. 20, SUPPL. 3

Research output: Contribution to journalArticle

Independent Living
Activities of Daily Living
Dementia
Clinical Trials
Self Report
104 Citations (Scopus)

Age and apolipoprotein E*4 allele effects on cerebrospinal fluid β-amyloid 42 in adults with normal cognition

Peskind, E. R., Li, G., Shofer, J., Quinn, J., Kaye, J., Clark, C. M., Farlow, M. R., DeCarli, C., Raskind, M. A., Schellenberg, G. D., Lee, V. M. Y. & Galasko, D. R., 2006, In : Archives of Neurology. 63, 7, p. 936-939 4 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Amyloid
Cognition
Cerebrospinal Fluid
Alleles
Medication Adherence
Medication Errors
Equipment and Supplies
Monitoring
Pharmaceutical Preparations
63 Citations (Scopus)

Aplicação da versão Brasileira da escala de avaliação clínica da demência (clinical dementia rating - CDR) em amostras de pacientes com demência

Translated title of the contribution: Application of the Brazilian version of the CDR scale in samples of dementia patientsMaia, A. L. G., Godinho, C., Ferreira, E. D., Almeida, V., Schuh, A., Kaye, J. & Chaves, M. L. F., 2006, In : Arquivos de Neuro-Psiquiatria. 64, 2 B, p. 485-489 5 p.

Research output: Contribution to journalArticle

Dementia
Vascular Dementia
Alzheimer Disease
National Institute of Neurological Disorders and Stroke
Education
29 Citations (Scopus)

Brain volume loss in MCI predicts dementia

Erten-Lyons, D., Howieson, D., Moore, M. M., Quinn, J., Sexton, G., Silbert, L. & Kaye, J., Jan 2006, In : Neurology. 66, 2, p. 233-235 3 p.

Research output: Contribution to journalArticle

Temporal Lobe
Dementia
Brain
Cognitive Dysfunction
29 Citations (Scopus)

Characterizing sleep problems in persons with Alzheimer's disease and normal elderly

Tractenberg, R. E., Singer, C. M. & Kaye, J., Mar 2006, In : Journal of Sleep Research. 15, 1, p. 97-103 7 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Sleep
Caregivers
Interviews
27 Citations (Scopus)

Cortical excitability and age-related volumetric MRI changes

Silbert, L., Nelson, C., Holman, S., Eaton, R., Oken, B., Lou, J. S. & Kaye, J., May 2006, In : Clinical Neurophysiology. 117, 5, p. 1029-1036 8 p.

Research output: Contribution to journalArticle

Transcranial Magnetic Stimulation
Cerebrospinal Fluid
Cortical Excitability
Neuroimaging
Healthy Volunteers
16 Citations (Scopus)

Dementia-free survival among centenarians: An evidence-based review

Calvert, J., Hollander-Rodriguez, J., Kaye, J. & Leahy, M., Sep 2006, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 61, 9, p. 951-956 6 p.

Research output: Contribution to journalArticle

Dementia
Survival
Publications
Research
Censuses
270 Citations (Scopus)

Effects of a γ-secretase inhibitor in a randomized study of patients with Alzheimer disease

Siemers, E. R., Quinn, J., Kaye, J., Farlow, M. R., Porsteinsson, A., Tariot, P., Zoulnouni, P., Galvin, J. E., Holtzman, D. M., Knopman, D. S., Satterwhite, J., Gonzales, C., Dean, R. A. & May, P. C., Feb 2006, In : Neurology. 66, 4, p. 602-604 3 p.

Research output: Contribution to journalArticle

Amyloid Precursor Protein Secretases
N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide
Alzheimer Disease
Randomized Controlled Trials
Pharmaceutical Preparations
4 Citations (Scopus)

Home health monitoring: A system to assess motor and cognitive funtion

Kaye, J. & Hayes, T., Jun 2006, In : Generations. 30, 2, p. 61-63 3 p.

Research output: Contribution to journalArticle

monitoring
Health
health
22 Citations (Scopus)

Neural networks for longitudinal studies in Alzheimer's disease

Tandon, R., Adak, S. & Kaye, J., Mar 2006, In : Artificial Intelligence in Medicine. 36, 3, p. 245-255 11 p.

Research output: Contribution to journalArticle

Longitudinal Studies
Alzheimer Disease
Neural networks
Neural Networks (Computer)
Databases
Aptitude
Cognition
Learning
Health
Monitoring
2005
62 Citations (Scopus)

apoE isoforms and measures of anxiety in probable AD patients and Apoe -/- mice

Robertson, J., Curley, J., Kaye, J., Quinn, J., Pfankuch, T. & Raber, J., May 2005, In : Neurobiology of Aging. 26, 5, p. 637-643 7 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Protein Isoforms
Anxiety
Apolipoprotein E3
Apolipoprotein E4
30 Citations (Scopus)

Asynchronous regional brain volume losses in presymptomatic to moderate AD

Kaye, J., Moore, M. M., Dame, A., Quinn, J., Camicioli, R., Howieson, D., Corbridge, E., Care, B., Nesbit, G. & Sexton, G., 2005, In : Journal of Alzheimer's Disease. 8, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

Dementia
Brain
Temporal Lobe
Prospective Studies
31 Citations (Scopus)

Corpus callosum in neurodegenerative diseases: Findings in Parkinson's disease

Wiltshire, K., Foster, S., Kaye, J., Small, B. J. & Camicioli, R., Nov 2005, In : Dementia and Geriatric Cognitive Disorders. 20, 6, p. 345-351 7 p.

Research output: Contribution to journalArticle

Corpus Callosum
Neurodegenerative Diseases
Parkinson Disease
Alzheimer Disease
Dementia
216 Citations (Scopus)

Differential loss of synaptic proteins in Alzheimer's disease: Implications for synaptic dysfunction

Reddy, P. H., Mani, G., Park, B., Jacques, J., Murdoch, G., Whetsell, W., Kaye, J. & Manczak, M., 2005, In : Journal of Alzheimer's Disease. 7, 2, p. 103-117 15 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Proteins
Brain
Parietal Lobe
Frontal Lobe
21 Citations (Scopus)

Magnetic resonance approaches to brain aging and Alzheimer disease-associated neuropathology

Anderson, V., Litvack, Z. N. & Kaye, J., Dec 2005, In : Topics in Magnetic Resonance Imaging. 16, 6, p. 439-452 14 p.

Research output: Contribution to journalArticle

Brain Diseases
Alzheimer Disease
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Brain
23 Citations (Scopus)

Patterns of dietary supplement usage in demographically diverse older people

Kishiyama, S. S., Leahy, M. J., Zitzelberger, T. A., Guariglia, R., Zajdel, D. P., Calvert, J., Kaye, J. & Oken, B., May 2005, In : Alternative Therapies in Health and Medicine. 11, 3, p. 48-53 6 p.

Research output: Contribution to journalArticle

Dietary Supplements
Complementary Therapies
Integrative Medicine
Yoga
San Francisco
18 Citations (Scopus)

Quantitative in vivo biomarkers of oxidative damage and their application to the diagnosis and management of Alzheimer's disease

Montine, T. J., Quinn, J., Montine, K. S., Kaye, J. & Breitner, J. C. S., 2005, In : Journal of Alzheimer's Disease. 8, 4, p. 359-367 9 p.

Research output: Contribution to journalArticle

F2-Isoprostanes
Alzheimer Disease
Biomarkers
Dementia
Oxidants
146 Citations (Scopus)

Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease

Zhang, J., Goodlett, D. R., Quinn, J., Peskind, E., Kaye, J., Zhou, Y., Pan, C., Yi, E., Eng, J., Wang, Q., Aebersold, R. H. & Montine, T. J., 2005, In : Journal of Alzheimer's Disease. 7, 2, p. 125-133 9 p.

Research output: Contribution to journalArticle

Proteomics
Cerebrospinal Fluid
Alzheimer Disease
Biomarkers
Cerebrospinal Fluid Proteins
39 Citations (Scopus)

Reduced CSF PLTP activity in Alzheimer's disease and other neurologic diseases; PLTP induces ApoE secretion in primary human astrocytes in vitro

Vuletic, S., Peskind, E. R., Marcovina, S. M., Quinn, J., Cheung, M. C., Kennedy, H., Kaye, J., Jin, L. W. & Albers, J. J., May 1 2005, In : Journal of Neuroscience Research. 80, 3, p. 406-413 8 p.

Research output: Contribution to journalArticle

Phospholipid Transfer Proteins
Cerebrospinal Fluid Proteins
Apolipoproteins E
Nervous System Diseases
Astrocytes
20 Citations (Scopus)

Role of biomarkers in studies of presymptomatic Alzheimer's disease

Morris, J. C., Quaid K, K. A., Holtzman, D. M., Kantarci, K., Kaye, J., Reiman, E. M., Klunk, W. E. & Siemers, E. R., Oct 2005, In : Alzheimer's and Dementia. 1, 2, p. 145-151 7 p.

Research output: Contribution to journalArticle

Asymptomatic Diseases
Alzheimer Disease
Biomarkers
Privacy
Amyloid Plaques
140 Citations (Scopus)

Safety and acceptability of the research lumbar puncture

Peskind, E. R., Riekse, R., Quinn, J., Kaye, J., Clark, C. M., Farlow, M. R., Decarli, C., Chabal, C., Vavrek, D., Raskind, M. A. & Galasko, D., Oct 2005, In : Alzheimer Disease and Associated Disorders. 19, 4, p. 220-225 6 p.

Research output: Contribution to journalArticle

Spinal Puncture
Post-Dural Puncture Headache
Safety
Research
Cerebrospinal Fluid
78 Citations (Scopus)

Symptoms of sleep disturbance in persons with Alzheimer's disease and normal elderly

Tractenberg, R. E., Singer, C. M. & Kaye, J., Jun 2005, In : Journal of Sleep Research. 14, 2, p. 177-185 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Sleep
Cognition
Depression
1330 Citations (Scopus)

Vitamin E and donepezil for the treatment of mild cognitive impairment

Petersen, R. C., Thomas, R. G., Grundman, M., Bennett, D., Doody, R., Ferris, S., Galasko, D., Jin, S., Kaye, J., Levey, A., Pfeiffer, E., Sano, M., Van Dyck, C. H. & Thal, L. J., Jun 9 2005, In : New England Journal of Medicine. 352, 23, p. 2379-2388 10 p.

Research output: Contribution to journalArticle

Vitamin E
Alzheimer Disease
Placebos
Apolipoprotein E4
Therapeutics
2004
91 Citations (Scopus)

Dementia assessment in primary care: Results from a study in three managed care systems

Boise, L., Neal, M. B. & Kaye, J., Jun 2004, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 59, 6, p. 621-626 6 p.

Research output: Contribution to journalArticle

Managed Care Programs
Dementia
Primary Health Care
Cholinesterase Inhibitors
Primary Care Physicians
89 Citations (Scopus)

Measurement of gelatinase B (MMP-9) in the cerebrospinal fluid of patients with vascular dementia and Alzheimer disease.

Adair, J. C., Charlie, J., Dencoff, J. E., Kaye, J., Quinn, J., Camicioli, R. M., Stetler-Stevenson, W. G. & Rosenberg, G. A., 2004, In : Stroke. 35, 6

Research output: Contribution to journalArticle

Vascular Dementia
Matrix Metalloproteinase 9
Vascular Diseases
Cerebrospinal Fluid
Alzheimer Disease
623 Citations (Scopus)

Mild Cognitive Impairment Can Be Distinguished from Alzheimer Disease and Normal Aging for Clinical Trials

Grundman, M., Petersen, R. C., Ferris, S. H., Thomas, R. G., Aisen, P. S., Bennett, D. A., Foster, N. L., Jack, C. R., Galasko, D. R., Doody, R., Kaye, J., Sano, M., Mohs, R., Gauthier, S., Kim, H. T., Jin, S., Schultz, A. N., Schafer, K., Mulnard, R., Van Dyck, C. H. & 4 others, Mintzer, J., Zamrini, E. Y., Cahn-Weiner, D. & Thal, L. J., Jan 2004, In : Archives of Neurology. 61, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Clinical Trials
Dementia
Multicenter Studies
Cognitive Dysfunction
5 Citations (Scopus)

Phytochemicals in Alzheimer disease: The development of clinical trials

Quinn, J., Kaye, J., Montine, T. & Stackman, R., 2004, In : Pharmaceutical Biology. 42, SUPPL., p. 64-73 10 p.

Research output: Contribution to journalArticle

Phytochemicals
Alzheimer disease
phytopharmaceuticals
clinical trials
Alzheimer Disease