Jeffrey Kaye

Professor

  • 31755 Citations
  • 91 h-Index
1976 …2020

Research output per year

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Research Output

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Article
2011

Spoken language derived measures for detecting mild cognitive impairment

Roark, B., Mitchell, M., Hosom, J. P., Hollingshead, K. & Kaye, J., Jul 28 2011, In : IEEE Transactions on Audio, Speech and Language Processing. 19, 7, p. 2081-2090 10 p., 5710404.

Research output: Contribution to journalArticle

129 Scopus citations

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

Villeda, S. A., Luo, J., Mosher, K. I., Zou, B., Britschgi, M., Bieri, G., Stan, T. M., Fainberg, N., Ding, Z., Eggel, A., Lucin, K. M., Czirr, E., Park, J. S., Couillard-Després, S., Aigner, L., Li, G., Peskind, E. R., Kaye, J. A., Quinn, J. F., Galasko, D. R. & 3 others, Xie, X. S., Rando, T. A. & Wyss-Coray, T., Sep 1 2011, In : Nature. 477, 7362, p. 90-96 7 p.

Research output: Contribution to journalArticle

838 Scopus citations

Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., Iwatsubo, T., Jack, C. R., Kaye, J., Montine, T. J., Park, D. C., Reiman, E. M., Rowe, C. C., Siemers, E., Stern, Y., Yaffe, K., Carrillo, M. C., Thies, B., Morrison-Bogorad, M., Wagster, M. V. & 1 others, Phelps, C. H., May 2011, In : Alzheimer's and Dementia. 7, 3, p. 280-292 13 p.

Research output: Contribution to journalArticle

3392 Scopus citations
2010

Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in alzheimer disease

Woltjer, R. L., Duerson, K., Fullmer, J. M., Mookherjee, P., Ryan, A. M., Montine, T. J., Kaye, J. A., Quinn, J. F., Silbert, L., Erten-Lyons, D., Leverenz, J. B., Bird, T. D., Pow, D. V., Tanaka, K., Watson, G. S. & Cook, D. G., Jul 1 2010, In : Journal of Neuropathology and Experimental Neurology. 69, 7, p. 667-676 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

Van Deerlin, V. M., Sleiman, P. M. A., Martinez-Lage, M., Chen-Plotkin, A., Wang, L. S., Graff-Radford, N. R., Dickson, D. W., Rademakers, R., Boeve, B. F., Grossman, M., Arnold, S. E., Mann, D. M. A., Pickering-Brown, S. M., Seelaar, H., Heutink, P., Van Swieten, J. C., Murrell, J. R., Ghetti, B., Spina, S., Grafman, J. & 80 others, Hodges, J., Spillantini, M. G., Gilman, S., Lieberman, A. P., Kaye, J. A., Woltjer, R. R., Bigio, E. H., Mesulam, M., Al-Sarraj, S., Troakes, C., Rosenberg, R. N., White, C. L., Ferrer, I., Lladó, A., Neumann, M., Kretzschmar, H. A., Hulette, C. M., Welsh-Bohmer, K. A., Miller, B. L., Alzualde, A., De Munain, A. L., McKee, A. C., Gearing, M., Levey, A. I., Lah, J. J., Hardy, J., Rohrer, J. D., Lashley, T., MacKenzie, I. R. A., Feldman, H. H., Hamilton, R. L., Dekosky, S. T., Van Der Zee, J., Kumar-Singh, S., Van Broeckhoven, C., Mayeux, R., Vonsattel, J. P. G., Troncoso, J. C., Kril, J. J., Kwok, J. B. J., Halliday, G. M., Bird, T. D., Ince, P. G., Shaw, P. J., Cairns, N. J., Morris, J. C., McLean, C. A., Decarli, C., Ellis, W. G., Freeman, S. H., Frosch, M. P., Growdon, J. H., Perl, D. P., Sano, M., Bennett, D. A., Schneider, J. A., Beach, T. G., Reiman, E. M., Woodruff, B. K., Cummings, J., Vinters, H. V., Miller, C. A., Chui, H. C., Alafuzoff, I., Hartikainen, P., Seilhean, D., Galasko, D., Masliah, E., Cotman, C. W., Tũón, M. T., Martínez, M. C. C., Munoz, D. G., Carroll, S. L., Marson, D., Riederer, P. F., Bogdanovic, N., Schellenberg, G. D., Hakonarson, H., Trojanowski, J. Q. & Lee, V. M. Y., Mar 2010, In : Nature genetics. 42, 3, p. 234-239 6 p.

Research output: Contribution to journalArticle

297 Scopus citations

Comparisons of plasma/serum micronutrients between Okinawan and oregonian elders: A pilot study

Dodge, H. H., Katsumata, Y., Todoriki, H., Yasura, S., Willcox, D. C., Bowman, G. L., Willcox, B., Leonard, S., Clemons, A., Oken, B. S., Kaye, J. A. & Traber, M. G., Oct 2010, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 65 A, 10, p. 1060-1067 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Neuroimaging and cognition in parkinson's disease dementia

Silbert, L. C. & Kaye, J., May 1 2010, In : Brain Pathology. 20, 3, p. 646-653 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Pilot study to show the feasibility of a multicenter trial of home-based assessment of people over 75 years old

Sano, M., Egelko, S., Ferris, S., Kaye, J., Hayes, T. L., Mundt, J. C., Donohue, M., Walter, S., Sun, S. & Sauceda-Cerda, L., Jul 1 2010, In : Alzheimer Disease and Associated Disorders. 24, 3, p. 256-263 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Predictors of the progression of dementia severity in Brazilian patients with Alzheimer's disease and vascular dementia

Chaves, M. L., Camozzato, A. L., Khler, C. & Kaye, J., Aug 30 2010, In : International Journal of Alzheimer's Disease. 673581.

Research output: Contribution to journalArticle

11 Scopus citations

The FAS gene, brain volume, and disease progression in Alzheimer's disease

Erten-Lyons, D., Jacobson, A., Kramer, P., Grupe, A. & Kaye, J., Mar 1 2010, In : Alzheimer's and Dementia. 6, 2, p. 118-124 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

The trajectory of gait speed preceding mild cognitive impairment

Buracchio, T., Dodge, H. H., Howieson, D., Wasserman, D. & Kaye, J., Aug 1 2010, In : Archives of Neurology. 67, 8, p. 980-986 7 p.

Research output: Contribution to journalArticle

236 Scopus citations

Unobtrusive and ubiquitous in-home monitoring: A methodology for continuous assessment of gait velocity in elders

Hagler, S., Austin, D., Hayes, T. L., Kaye, J. & Pavel, M., Apr 2010, In : IEEE Transactions on Biomedical Engineering. 57, 4, p. 813-820 8 p., 5339193.

Research output: Contribution to journalArticle

106 Scopus citations

Uric acid as a CNS antioxidant

Bowman, G. L., Shannon, J., Frei, B., Kaye, J. A. & Quinn, J. F., 2010, In : Journal of Alzheimer's Disease. 19, 4, p. 1331-1336 6 p.

Research output: Contribution to journalArticle

105 Scopus citations
2009

Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease

Roher, A. E., Esh, C. L., Kokjohn, T. A., Castaño, E. M., Van Vickle, G. D., Kalback, W. M., Patton, R. L., Luehrs, D. C., Daugs, I. D., Kuo, Y. M., Emmerling, M. R., Soares, H., Quinn, J. F., Kaye, J., Connor, D. J., Silverberg, N. B., Adler, C. H., Seward, J. D., Beach, T. G. & Sabbagh, M. N., Jan 1 2009, In : Alzheimer's and Dementia. 5, 1, p. 18-29 12 p.

Research output: Contribution to journalArticle

194 Scopus citations

Ascorbic acid and rates of cognitive decline in Alzheimer's disease

Bowman, G. L., Dodge, H., Frei, B., Calabrese, C., Oken, B. S., Kaye, J. A. & Quinn, J. F., 2009, In : Journal of Alzheimer's Disease. 16, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

A study of medication-taking and unobtrusive, intelligent reminding.

Hayes, T. L., Cobbinah, K., Dishongh, T., Kaye, J. A., Kimel, J., Labhard, M., Leen, T., Lundell, J., Ozertem, U., Pavel, M., Philipose, M., Rhodes, K. & Vurgun, S., Oct 2009, In : Telemedicine journal and e-health : the official journal of the American Telemedicine Association. 15, 8, p. 770-776 7 p.

Research output: Contribution to journalArticle

42 Scopus citations

Cognitive impairment risk: White matter hyperintensity progression matters

Silbert, L. C., Howieson, D. B., Dodge, H. & Kaye, J. A., Jul 2009, In : Neurology. 73, 2, p. 120-125 6 p.

Research output: Contribution to journalArticle

71 Scopus citations

Early diagnosis of Alzheimer's disease and mild cognitive impairment: Imaging, biomarkers, and technology

Buracchio, T. & Kaye, J., Apr 1 2009, In : Generations. 33, 1, p. 18-23 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Exceptional brain aging in a rural population-based cohort

Kaye, J., Michael, Y., Calvert, J., Leahy, M., Crawford, D. & Kramer, P., Jun 1 2009, In : Journal of Rural Health. 25, 3, p. 320-325 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Factors associated with resistance to dementia despite high Alzheimer disease pathology

Erten-Lyons, D., Woltjer, R. L., Dodge, H., Nixon, R., Vorobik, R., Calvert, J. F., Leahy, M., Montine, T. & Kaye, J., Jan 27 2009, In : Neurology. 72, 4, p. 354-360 7 p.

Research output: Contribution to journalArticle

99 Scopus citations

Ginkgo biloba prevention trials: More than an ounce of prevention learned

Kaye, J., May 1 2009, In : Archives of Neurology. 66, 5, p. 652-654 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Incidence of mild cognitive impairment and alzheimer disease in southern Brazil

Chaves, M. L., Camozzato, A. L., Godinho, C., Piazenski, I. & Kaye, J., Sep 1 2009, In : Journal of Geriatric Psychiatry and Neurology. 22, 3, p. 181-187 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Medication adherence in healthy elders: Small cognitive changes make a big difference

Hayes, T. L., Larimer, N., Adami, A. & Kaye, J. A., Jun 1 2009, In : Journal of Aging and Health. 21, 4, p. 567-580 14 p.

Research output: Contribution to journalArticle

109 Scopus citations

Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease

Price, J. L., McKeel, D. W., Buckles, V. D., Roe, C. M., Xiong, C., Grundman, M., Hansen, L. A., Petersen, R. C., Parisi, J. E., Dickson, D. W., Smith, C. D., Davis, D. G., Schmitt, F. A., Markesbery, W. R., Kaye, J., Kurlan, R., Hulette, C., Kurland, B. F., Higdon, R., Kukull, W. & 1 others, Morris, J. C., Jul 1 2009, In : Neurobiology of Aging. 30, 7, p. 1026-1036 11 p.

Research output: Contribution to journalArticle

412 Scopus citations

Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease

Britschgi, M., Olin, C. E., Johns, H. T., Takeda-Uchimura, Y., Lemieux, M. C., Rufibach, K., Rajadas, J., Zhang, H., Tomooka, B., Robinson, W. H., Clark, C. M., Fagan, A. M., Galasko, D. R., Holtzman, D. M., Jutel, M., Kaye, J. A., Lemere, C. A., Leszek, J., Li, G., Peskind, E. R. & 4 others, Quinn, J. F., Yesavage, J. A., Ghiso, J. A. & Wyss-Coray, T., Jul 21 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 29, p. 12145-12150 6 p.

Research output: Contribution to journalArticle

110 Scopus citations

Predictors of normal and successful aging among urban-dwelling elderly brazilians

Chaves, M. L., Camozzato, A. L., Eizirik, C. L. & Kaye, J., 2009, In : Journals of Gerontology - Series B Psychological Sciences and Social Sciences. 64, 5, p. 597-602 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Technology use by rural and urban oldest old

Calvert, J. F., Kaye, J., Leahy, M., Hexem, K. & Carlson, N., Jun 19 2009, In : Technology and Health Care. 17, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Wechsler Memory Scale-III Faces test performance in patients with mild cognitive impairment and mild Alzheimer's disease

Seelye, A. M., Howieson, D. B., Wild, K. V., Moore, M. M. & Kaye, J. A., Aug 1 2009, In : Journal of Clinical and Experimental Neuropsychology. 31, 6, p. 682-688 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2008

An aberrant protein complex in CSF as a biomarker of Alzheimer disease

Lovell, M. A., Lynn, B. C., Xiong, S., Quinn, J. F., Kaye, J. & Markesbery, W. R., Jun 3 2008, In : Neurology. 70, 23, p. 2212-2218 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

A randomized placebo-controlled trial of Ginkgo biloba for the prevention of cognitive decline

Dodge, H. H., Zitzelberger, T., Oken, B. S., Howieson, D. & Kaye, J., May 2008, In : Neurology. 70, 19 PART 2, p. 1809-1817 9 p.

Research output: Contribution to journalArticle

120 Scopus citations

Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient

Lerenz, J. B., Hamilton, R., Tsuang, D. W., Schantz, A., Vavrek, D., Larson, E. B., Kukull, W. A., Lopez, O., Galasko, D., Masliah, E., Kaye, J., Woltjer, R., Clark, C., Trojanowski, J. Q. & Montine, T. J., Apr 1 2008, In : Brain Pathology. 18, 2, p. 220-224 5 p.

Research output: Contribution to journalArticle

79 Scopus citations

Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline

Silbert, L. C., Nelson, C., Howieson, D. B., Moore, M. M. & Kaye, J. A., Jul 8 2008, In : Neurology. 71, 2, p. 108-113 6 p.

Research output: Contribution to journalArticle

158 Scopus citations

Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI

the Alzheimer’s Disease Cooperative Study (ADCS), Sep 1 2008, In : Neurobiology of Aging. 29, 9, p. 1285-1295 11 p.

Research output: Contribution to journalArticle

110 Scopus citations

Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels

Bekris, L. M., Millard, S. P., Galloway, N. M., Vuletic, S., Albers, J. J., Li, G., Galasko, D. R., DeCarli, C., Farlow, M. R., Clark, C. M., Quinn, J. F., Kaye, J. A., Schellenberg, G. D., Tsuang, D., Peskind, E. R. & Yu, C. E., 2008, In : Journal of Alzheimer's Disease. 13, 3, p. 255-266 12 p.

Research output: Contribution to journalArticle

58 Scopus citations

Trajectories of brain loss in aging and the development of cognitive impairment

Carlson, N. E., Moore, M. M., Dame, A., Howieson, D., Silbert, L. C., Quinn, J. F. & Kaye, J. A., Mar 2008, In : Neurology. 70, 11, p. 828-833 6 p.

Research output: Contribution to journalArticle

98 Scopus citations

Trajectory of mild cognitive impairment onset

Howieson, D. B., Carlson, N. E., Moore, M. M., Wasserman, D., Abendroth, C. D., Payne-Murphy, J. & Kaye, J. A., Mar 1 2008, In : Journal of the International Neuropsychological Society. 14, 2, p. 192-198 7 p.

Research output: Contribution to journalArticle

101 Scopus citations

Translational gene mapping of cognitive decline

Wilmot, B., McWeeney, S. K., Nixon, R. R., Montine, T. J., Laut, J., Harrington, C. A., Kaye, J. A. & Kramer, P. L., Apr 1 2008, In : Neurobiology of Aging. 29, 4, p. 524-541 18 p.

Research output: Contribution to journalArticle

21 Scopus citations

Unobtrusive assessment of activity patterns associated with mild cognitive impairment

Hayes, T. L., Abendroth, F., Adami, A., Pavel, M., Zitzelberger, T. A. & Kaye, J. A., Nov 1 2008, In : Alzheimer's and Dementia. 4, 6, p. 395-405 11 p.

Research output: Contribution to journalArticle

99 Scopus citations

xix-xxii

Qizilbash, N., Schneider, L. S., Chui, H., Tariot, P., Brodaty, H., Kaye, J. & Erkinjuntti, T., Jan 14 2008, In : Unknown Journal. p. 1-904 904 p.

Research output: Contribution to journalArticle

2007

A simple method to rule out dementia with temporal orientation

Tractenberg, R. E., Weiner, M. F., Aisen, P. S., Kaye, J. A. & Fuh, J. L., Jan 1 2007, In : Alzheimer's and Dementia. 3, 1, p. 28-32 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Blood-brain barrier impairment in Alzheimer disease: Stability and functional significance

Bowman, G. L., Kaye, J. A., Moore, M., Waichunas, D., Carlson, N. E. & Quinn, J. F., May 1 2007, In : Neurology. 68, 21, p. 1809-1814 6 p.

Research output: Contribution to journalArticle

185 Scopus citations

Brain volumes in Guam dementia vs Parkinson dementia complex vs aging Chamorro adults

Kaye, J. A., Moore, M. M., Galasko, D., Craig, U. K., Adonay, R. & Silbert, L. C., Jul 1 2007, In : Neurology. 69, 2, p. 196-199 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

Ray, S., Britschgi, M., Herbert, C., Takeda-Uchimura, Y., Boxer, A., Blennow, K., Friedman, L. F., Galasko, D. R., Jutel, M., Karydas, A., Kaye, J. A., Leszek, J., Miller, B. L., Minthon, L., Quinn, J. F., Rabinovici, G. D., Robinson, W. H., Sabbagh, M. N., So, Y. T., Sparks, D. L. & 5 others, Tabaton, M., Tinklenberg, J., Yesavage, J. A., Tibshirani, R. & Wyss-Coray, T., Nov 1 2007, In : Nature medicine. 13, 11, p. 1359-1362 4 p.

Research output: Contribution to journalArticle

767 Scopus citations

Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases

Nakashima-Yasuda, H., Uryu, K., Robinson, J., Xie, S. X., Hurtig, H., Duda, J. E., Arnold, S. E., Siderowf, A., Grossman, M., Leverenz, J. B., Woltjer, R., Lopez, O. L., Hamilton, R., Tsuang, D. W., Galasko, D., Masliah, E., Kaye, J., Clark, C. M., Montine, T. J., Lee, V. M. Y. & 1 others, Trojanowski, J. Q., Sep 1 2007, In : Acta Neuropathologica. 114, 3, p. 221-229 9 p.

Research output: Contribution to journalArticle

268 Scopus citations
15 Scopus citations

CSF tau/Aβ42 ratio for increased risk of mild cognitive impairment: A follow-up study

Li, G., Sokal, I., Quinn, J. F., Leverenz, J. B., Brodey, M., Schellenberg, G. D., Kaye, J. A., Raskind, M. A., Zhang, J., Peskind, E. R. & Montine, T. J., Aug 1 2007, In : Neurology. 69, 7, p. 631-639 9 p.

Research output: Contribution to journalArticle

209 Scopus citations

Cycad exposure and risk of dementia, MCI, and PDC in the Chamorro population of Guam

Borenstein, A. R., Mortimer, J. A., Schofield, E., Wu, Y., Salmon, D. P., Gamst, A., Olichney, J., Thal, L. J., Silbert, L., Kaye, J., Craig, U. L., Schellenberg, G. D. & Galasko, D. R., May 1 2007, In : Neurology. 68, 21, p. 1764-1771 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Physical activity and the risk of dementia in oldest old

Sumic, A., Michael, Y. L., Carlson, N. E., Howieson, D. B. & Kaye, J. A., Apr 1 2007, In : Journal of Aging and Health. 19, 2, p. 242-259 18 p.

Research output: Contribution to journalArticle

72 Scopus citations