Jeffrey Kaye

Professor

  • 28389 Citations
  • 87 h-Index
1976 …2020
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Research Output 1986 2019

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Article
2014
13 Citations (Scopus)

Regularity and predictability of human mobility in personal space

Austin, D., Cross, R. M., Hayes, T. & Kaye, J., Feb 27 2014, In : PLoS One. 9, 2, e90256.

Research output: Contribution to journalArticle

Personal Space
Scaling laws
Monitoring
functional status
monitoring
30 Citations (Scopus)

Sleep habits in mild cognitive impairment

Hayes, T. L., Riley, T., Mattek, N., Pavel, M. & Kaye, J., 2014, In : Alzheimer Disease and Associated Disorders. 28, 2, p. 145-150 6 p.

Research output: Contribution to journalArticle

Habits
Sleep
Self Report
Volunteers
Independent Living
7 Citations (Scopus)
Independent Living
Long-Term Care
Odds Ratio
Confidence Intervals
Sleep
10 Citations (Scopus)

Tools for advancing research into social networks and cognitive function in older adults

Dodge, H., Ybarra, O. & Kaye, J., 2014, In : International Psychogeriatrics. 26, 4, p. 533-539 7 p.

Research output: Contribution to journalArticle

Social Networking
Interpersonal Relations
Social Support
Cognition
Research
24 Citations (Scopus)

Unobtrusive in-home detection of time spent out-of-home with applications to loneliness and physical activity

Petersen, J., Austin, D., Kaye, J., Pavel, M. & Hayes, T. L., Sep 1 2014, In : IEEE Journal of Biomedical and Health Informatics. 18, 5, p. 1590-1596 7 p.

Research output: Contribution to journalArticle

Loneliness
Logistics
Health
Exercise
Activities of Daily Living
54 Citations (Scopus)

Unobtrusive measurement of daily computer use to detect mild cognitive impairment

Kaye, J., Mattek, N., Dodge, H., Campbell, I., Hayes, T., Austin, D., Hatt, W., Wild, K., Jimison, H. & Pavel, M., Jan 2014, In : Alzheimer's and Dementia. 10, 1, p. 10-17 8 p.

Research output: Contribution to journalArticle

Cognitive Dysfunction
Sex Education
Activities of Daily Living
Longitudinal Studies
Volunteers
2013
105 Citations (Scopus)

Aging, the central nervous system, and mobility

Rosso, A. L., Studenski, S. A., Chen, W. G., Aizenstein, H. J., Alexander, N. B., Bennett, D. A., Black, S. E., Camicioli, R., Carlson, M. C., Ferrucci, L., Guralnik, J. M., Hausdorff, J. M., Kaye, J., Launer, L. J., Lipsitz, L. A., Verghese, J. & Rosano, C., Nov 2013, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 11, p. 1379-1386 8 p.

Research output: Contribution to journalArticle

Mobility Limitation
Central Nervous System
Nervous System Diseases
National Institute on Aging (U.S.)
Research Personnel
133 Citations (Scopus)

APOE ε4 increases risk for dementia in pure synucleinopathies

Tsuang, D., Leverenz, J. B., Lopez, O. L., Hamilton, R. L., Bennett, D. A., Schneider, J. A., Buchman, A. S., Larson, E. B., Crane, P. K., Kaye, J., Kramer, P., Woltjer, R. R., Trojanowski, J. Q., Weintraub, D., Chen-Plotkin, A. S., Irwin, D. J., Rick, J., Schellenberg, G. D., Watson, G. S., Kukull, W. & 13 others, Nelson, P. T., Jicha, G. A., Neltner, J. H., Galasko, D., Masliah, E., Quinn, J., Chung, K. K., Yearout, D., Mata, I. F., Wan, J. Y., Edwards, K. L., Montine, T. J. & Zabetian, C. P., 2013, In : JAMA Neurology. 70, 2, p. 223-228 6 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Dementia
Lewy Body Disease
Alzheimer Disease
Parkinson Disease
10 Citations (Scopus)

Dementia specialists and early adoption of amyloid imaging

Klein, E. & Kaye, J., 2013, In : Journal of Alzheimer's Disease. 33, 2, p. 445-450 6 p.

Research output: Contribution to journalArticle

Amyloid
Dementia
Alzheimer Disease
Counseling
Genetic Testing
11 Citations (Scopus)

Developing dementia prevention trials: Baseline report of the home-based assessment study

Sano, M., Egelko, S., Donohue, M., Ferris, S., Kaye, J., Hayes, T. L., Mundt, J. C., Sun, C. K., Paparello, S. & Aisen, P. S., Oct 2013, In : Alzheimer Disease and Associated Disorders. 27, 4, p. 356-362 7 p.

Research output: Contribution to journalArticle

Dementia
Postal Service
Internet
Technology
Efficiency
71 Citations (Scopus)

Efficacy of cognitive rehabilitation therapies for mild cognitive impairment (MCI) in older adults: Working toward a theoretical model and evidence-based interventions

Huckans, M., Hutson, L., Twamley, E., Jak, A., Kaye, J. & Storzbach, D., Mar 2013, In : Neuropsychology Review. 23, 1, p. 63-80 18 p.

Research output: Contribution to journalArticle

Cognitive Therapy
Theoretical Models
Rehabilitation
Dementia
Cognitive Dysfunction
141 Citations (Scopus)

Imaging markers for Alzheimer disease: Which vs how

Frisoni, G. B., Bocchetta, M., Chételat, G., Rabinovici, G. D., De Leon, M. J., Kaye, J., Reiman, E. M., Scheltens, P., Barkhof, F., Black, S. E., Brooks, D. J., Carrillo, M. C., Fox, N. C., Herholz, K., Nordberg, A., Jack, C. R., Jagust, W. J., Johnson, K. A., Rowe, C. C., Sperling, R. A. & 5 others, Thies, W., Wahlund, L. O., Weiner, M. W., Pasqualetti, P. & DeCarli, C., Jul 30 2013, In : Neurology. 81, 5, p. 487-500 14 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Fluorodeoxyglucose F18
Single-Photon Emission-Computed Tomography
Amyloid
48 Citations (Scopus)

Neuropathologic basis of age-associated brain atrophy

Erten-Lyons, D., Dodge, H., Woltjer, R. R., Silbert, L., Howieson, D., Kramer, P. & Kaye, J., 2013, In : JAMA Neurology. 70, 5, p. 616-622 7 p.

Research output: Contribution to journalArticle

Atrophy
Brain
Dementia
Alzheimer Disease
Neurofibrillary Tangles
103 Citations (Scopus)

Neuropathologic basis of white matter hyperintensity accumulation with advanced age

Erten-Lyons, D., Woltjer, R. R., Kaye, J., Mattek, N., Dodge, H., Green, S., Tran, H., Howieson, D., Wild, K. & Silbert, L., Sep 10 2013, In : Neurology. 81, 11, p. 977-983 7 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Arteriolosclerosis
Pallor
Atherosclerosis
Pathology
27 Citations (Scopus)

Plasma omega-3 PUFA and white matter mediated executive decline in older adults

Bowman, G., Dodge, H., Mattek, N., Barbey, A. K., Silbert, L., Shinto, L., Howieson, D., Kaye, J. & Quinn, J., 2013, In : Frontiers in Aging Neuroscience. 5, DEC, Article 92.

Research output: Contribution to journalArticle

Executive Function
Cognition
Eicosapentaenoic Acid
Docosahexaenoic Acids
Omega-3 Fatty Acids
29 Citations (Scopus)

The role of technology and engineering models in transforming healthcare

Pavel, M., Jimison, H. B., Wactlar, H. D., Hayes, T. L., Barkis, W., Skapik, J. & Kaye, J., 2013, In : IEEE Reviews in Biomedical Engineering. 6, p. 156-177 22 p., 6490450.

Research output: Contribution to journalArticle

Health
Information technology
Biomedical engineering
Mobile computing
Learning systems
47 Citations (Scopus)

Willingness of older adults to share data and privacy concerns after exposure to unobtrusive home monitoring

Boise, L., Wild, K., Mattek, N., Ruhl, M., Dodge, H. & Kaye, J., 2013, In : Gerontechnology. 11, 3, p. 428-435 8 p.

Research output: Contribution to journalArticle

Privacy
Technology
Monitoring
Cognition
Health
2012
18 Citations (Scopus)

ADAM10 expression and promoter haplotype in Alzheimer's disease

Bekris, L. M., Lutz, F., Li, G., Galasko, D. R., Farlow, M. R., Quinn, J., Kaye, J., Leverenz, J. B., Tsuang, D. W., Montine, T. J., Peskind, E. R. & Yu, C. E., Sep 2012, In : Neurobiology of Aging. 33, 9

Research output: Contribution to journalArticle

Haplotypes
Alzheimer Disease
Amyloid Precursor Protein Secretases
Amyloid Plaques
Brain
135 Citations (Scopus)

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

Whitcomb, D. C., LaRusch, J., Krasinskas, A. M., Klei, L., Smith, J. P., Brand, R. E., Neoptolemos, J. P., Lerch, M. M., Tector, M., Sandhu, B. S., Guda, N. M., Orlichenko, L., Alkaade, S., Amann, S. T., Anderson, M. A., Baillie, J., Banks, P. A., Conwell, D., Coté, G. A., Cotton, P. B. & 178 others, DiSario, J., Farrer, L. A., Forsmark, C. E., Johnstone, M., Gardner, T. B., Gelrud, A., Greenhalf, W., Haines, J. L., Hartman, D. J., Hawes, R. A., Lawrence, C., Lewis, M., Mayerle, J., Mayeux, R., Melhem, N. M., Money, M. E., Muniraj, T., Papachristou, G. I., Pericak-Vance, M. A., Romagnuolo, J., Schellenberg, G. D., Sherman, S., Simon, P., Singh, V. P., Slivka, A., Stolz, D., Sutton, R., Weiss, F. U., Wilcox, C. M., Zarnescu, N. O., Wisniewski, S. R., O'Connell, M. R., Kienholz, M. L., Roeder, K., Barmada, M. M., Yadav, D., Devlin, B., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barnes, L. L., Beach, T. G., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton-Nelson, K. L., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., Kukul, W. A., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lin, C. F., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., MacK, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrel, J. R., Naj, A. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rosen, H. J., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsatte, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. R., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Dec 2012, In : Nature Genetics. 44, 12, p. 1349-1354 6 p.

Research output: Contribution to journalArticle

Pancreatitis
Alcohols
Claudin-2
Hemizygote
Alleles
37 Citations (Scopus)

Computer-related self-efficacy and anxiety in older adults with and without mild cognitive impairment

Wild, K., Mattek, N. C., Maxwell, S. A., Dodge, H., Jimison, H. B. & Kaye, J., Nov 2012, In : Alzheimer's and Dementia. 8, 6, p. 544-552 9 p.

Research output: Contribution to journalArticle

Self Efficacy
Anxiety
Cognitive Dysfunction
Aptitude
Sex Education
35 Citations (Scopus)

Dyslipidemia and blood-brain barrier integrity in Alzheimer's disease

Bowman, G., Kaye, J. & Quinn, J., 2012, In : Current Gerontology and Geriatrics Research. 2012, 184042.

Research output: Contribution to journalArticle

Dyslipidemias
Blood-Brain Barrier
Alzheimer Disease
Triglycerides
HDL Cholesterol
121 Citations (Scopus)

Evidence for a role of the rare p.A152T variant in mapt in increasing the risk for FTD-spectrum and Alzheimer's diseases

Coppola, G., Chinnathambi, S., Lee, J. J., Dombroski, B. A., Baker, M. C., Soto-ortolaza, A. I., Lee, S. E., Klein, E., Huang, A. Y., Sears, R., Lane, J. R., Karydas, A. M., Kenet, R. O., Biernat, J., Wang, L. S., Cotman, C. W., Decarli, C. S., Levey, A. I., Ringman, J. M., Mendez, M. F. & 210 others, Chui, H. C., Le ber, I., Brice, A., Lupton, M. K., Preza, E., Lovestone, S., Powell, J., Graff-radford, N., Petersen, R. C., Boeve, B. F., Lippa, C. F., Bigio, E. H., Mackenzie, I., Finger, E., Kertesz, A., Caselli, R. J., Gearing, M., Juncos, J. L., Ghetti, B., Spina, S., Bordelon, Y. M., Tourtellotte, W. W., Frosch, M. P., Vonsattel, J. P. G., Zarow, C., Beach, T. G., Albin, R. L., Lieberman, A. P., Lee, V. M., Trojanowski, J. Q., Van deerlin, V. M., Bird, T. D., Galasko, D. R., Masliah, E., White, C. L., Troncoso, J. C., Hannequin, D., Boxer, A. L., Geschwind, M. D., Kumar, S., Mandelkow, E. M., Wszolek, Z. K., Uitti, R. J., Dickson, D. W., Haines, J. L., Mayeux, R., Pericak-vance, M. A., Farrer, L. A., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barmada, M. M., Beach, T., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buros, J., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cotman, C. W., Crane, P. K., Cruchaga, C., Cummings, J. L., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Diaz-Arrastia, R., Dick, M., Dickson, D. W., Dombroski, B. A., Duara, R., Ellis, W. G., Ertekin-Taner, N. N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gallins, P. J., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Giordani, B., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Johnson, N., Jun, G., Kamboh, M. I., Karlawish, J., Karydas, A., Kauwe, J. S. K., Kaye, J., Kim, R., Koo, E. H., Kowall, N. W., Kramer, P., Kukull, W. A., Lah, J. J., Larson, E. B., Levey, A. I., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Myers, A. J., Naj, A. C., Nowotny, P., Parisi, J. E., Perl, D. P., Peskind, E., Petersen, R. C., Poon, W. W., Potter, H., Quinn, J., Raj, A., Rajbhandary, R. A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W., Shelanski, M. L., Slifer, M. A., Smith, C. D., Sonnen, J. A., Spina, S., George-Hyslop, P. S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. R., Younkin, S. G., Ross, O. A., Rademakers, R., Schellenberg, G. D., Miller, B. L., Mandelkow, E. & Geschwind, D. H., 2012, In : Human Molecular Genetics. 21, 15, p. 3500-3512 13 p., dds161.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Frontotemporal Dementia
Microtubule-Associated Proteins
Microtubules
tau Proteins
81 Citations (Scopus)

GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology

Tsuang, D., Leverenz, J. B., Lopez, O. L., Hamilton, R. L., Bennett, D. A., Schneider, J. A., Buchman, A. S., Larson, E. B., Crane, P. K., Kaye, J., Kramer, P., Woltjer, R. R., Kukull, W., Nelson, P. T., Jicha, G. A., Neltner, J. H., Galasko, D., Masliah, E., Trojanowski, J. Q., Schellenberg, G. D. & 8 others, Yearout, D., Huston, H., Fritts-Penniman, A., Mata, I. F., Wan, J. Y., Edwards, K. L., Montine, T. J. & Zabetian, C. P., Nov 6 2012, In : Neurology. 79, 19, p. 1944-1950 7 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Alzheimer Disease
Pathology
Mutation
Parkinson Disease
79 Citations (Scopus)

In-home walking speeds and variability trajectories associated with mild cognitive impairment

Dodge, H., Mattek, N. C., Austin, D., Hayes, T. L. & Kaye, J., Jun 12 2012, In : Neurology. 78, 24, p. 1946-1952 7 p.

Research output: Contribution to journalArticle

Cognition
Phase Transition
Dementia
Walking Speed
Cognitive Dysfunction
117 Citations (Scopus)

Nutrient biomarker patterns, cognitive function, and MRI measures of brain aging

Bowman, G., Silbert, L., Howieson, D., Dodge, H., Traber, M. G., Frei, B., Kaye, J., Shannon, J. J. & Quinn, J., Jan 24 2012, In : Neurology. 78, 4, p. 241-249 9 p.

Research output: Contribution to journalArticle

Cognition
Biomarkers
Food
Brain
Thiamine
5 Citations (Scopus)

Nutrient biomarker patterns, cognitive function, and MRI measures of brain aging

Bowman, G., Silbert, L., Dodge, H., Quinn, J. & Kaye, J., Apr 17 2012, In : Neurology. 78, 16, p. 1281-1282 2 p.

Research output: Contribution to journalArticle

Nutritional Status
Cognition
Biomarkers
Food
Brain
53 Citations (Scopus)

One walk a year to 1000 within a year: Continuous in-home unobtrusive gait assessment of older adults

Kaye, J., Mattek, N., Dodge, H., Buracchio, T., Austin, D., Hagler, S., Pavel, M. & Hayes, T., Feb 2012, In : Gait and Posture. 35, 2, p. 197-202 6 p.

Research output: Contribution to journalArticle

Gait
Walking
Aptitude
Neuropsychological Tests
Periodicity
4 Citations (Scopus)

Random local temporal structure of category fluency responses

Meyer, D. J., Messer, J., Singh, T., Thomas, P. J., Woyczynski, W. A., Kaye, J. & Lerner, A. J., Apr 2012, In : Journal of Computational Neuroscience. 32, 2, p. 213-231 19 p.

Research output: Contribution to journalArticle

Semantics
Dementia
Research
Cognitive Dysfunction
23 Citations (Scopus)
Communication
Technology
Aptitude
Health
Adult Children
13 Citations (Scopus)

Review of selected databases of longitudinal aging studies

Erten-Lyons, D., Sherbakov, L. O., Piccinin, A. M., Hofer, S., Dodge, H., Quinn, J., Woltjer, R. R., Kramer, P. L. & Kaye, J., Nov 2012, In : Alzheimer's and Dementia. 8, 6, p. 584-589 6 p.

Research output: Contribution to journalArticle

Longitudinal Studies
Databases
Alzheimer Disease
34 Citations (Scopus)

Serum vitamin d concentrations are associated with falling and cognitive function in older adults

Peterson, A., Mattek, N., Clemons, A., Bowman, G., Buracchio, T., Kaye, J. & Quinn, J., Oct 2012, In : Journal of Nutrition, Health and Aging. 16, 10, p. 898-901 4 p.

Research output: Contribution to journalArticle

Accidental Falls
Vitamin D
Vitamins
Cognition
Serum
15 Citations (Scopus)
Toilet Facilities
Insurance Benefits
Health
Self Report
Kitchens
9 Citations (Scopus)

Tau phosphorylation pathway genes and cerebrospinal fluid tau levels in Alzheimer's disease

Bekris, L. M., Millard, S., Lutz, F., Li, G., Galasko, D. R., Farlow, M. R., Quinn, J., Kaye, J., Leverenz, J. B., Tsuang, D. W., Yu, C. E. & Peskind, E. R., Oct 2012, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 159 B, 7, p. 874-883 10 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Alzheimer Disease
Phosphorylation
Phosphoric Monoester Hydrolases
Genes
4 Citations (Scopus)

The ADNI Publication Policy: Commensurate recognition of critical contributors who are not authors

Hurko, O., Black, S. E., Doody, R., Doraiswamy, P. M., Gamst, A., Kaye, J., Obisesan, T. O., Rusinek, H., Scharre, D., Sperling, R., Weiner, M. W. & Green, R. C., Feb 15 2012, In : NeuroImage. 59, 4, p. 4196-4200 5 p.

Research output: Contribution to journalArticle

Neuroimaging
Publications
Alzheimer Disease
Biomedical Research
Research Design
53 Citations (Scopus)

Trajectory of white matter hyperintensity burden preceding mild cognitive impairment

Silbert, L., Dodge, H., Perkins, L. G., Sherbakov, L., Lahna, D., Erten-Lyons, D., Woltjer, R. R., Shinto, L. & Kaye, J., Aug 21 2012, In : Neurology. 79, 8, p. 741-747 7 p.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Dementia
Alzheimer Disease
White Matter
Cognitive Dysfunction
44 Citations (Scopus)

Trends in the prevalence of dementia in Japan

Dodge, H., Buracchio, T. J., Fisher, G. G., Kiyohara, Y., Meguro, K., Tanizaki, Y. & Kaye, J., 2012, In : International Journal of Alzheimer's Disease. 956354.

Research output: Contribution to journalArticle

Dementia
Japan
Vascular Dementia
Alzheimer Disease
Vascular Diseases
2 Citations (Scopus)

Using the Guttman scale to define and estimate measurement error in items over time: The case of cognitive decline and the meaning of "points lost"

Tractenberg, R. E., Yumoto, F., Aisen, P. S., Kaye, J. & Mislevy, R. J., Feb 17 2012, In : PLoS One. 7, 2, e30019.

Research output: Contribution to journalArticle

Measurement errors
Delayed Diagnosis
Psychometrics
Reliability theory
testing
2011
58 Citations (Scopus)

Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study

Kramer, P. L., Xu, H., Woltjer, R. R., Westaway, S., Clark, D., Erten-Lyons, D., Kaye, J., Welsh-Bohmer, K. A., Troncoso, J. C., Markesbery, W. R., Petersen, R. C., Turner, R. S., Kukull, W. A., Bennett, D. A., Galasko, D., Morris, J. C. & Ott, J., Dec 2011, In : Neurobiology of Aging. 32, 12, p. 2113-2122 10 p.

Research output: Contribution to journalArticle

Neurofibrillary Tangles
Alzheimer Disease
Genome
Pathology
Amyloid
41 Citations (Scopus)

Alzheimer's disease and non-demented high pathology control nonagenarians: Comparing and contrasting the biochemistry of cognitively successful aging

Maarouf, C. L., Daugs, I. D., Kokjohn, T. A., Walker, D. G., Hunter, J. M., Kruchowsky, J. C., Woltjer, R. R., Kaye, J., Castaño, E. M., Sabbagh, M. N., Beach, T. G. & Roher, A. E., Nov 7 2011, In : PLoS One. 6, 11, e27291.

Research output: Contribution to journalArticle

Biochemistry
Pathology
amyloid
Alzheimer disease
biochemistry
31 Citations (Scopus)

Amyloid precursor protein (APP) processing genes and cerebrospinal fluid APP cleavage product levels in Alzheimer's disease

Bekris, L. M., Galloway, N. M., Millard, S., Lockhart, D., Li, G., Galasko, D. R., Farlow, M. R., Clark, C. M., Quinn, J., Kaye, J., Schellenberg, G. D., Leverenz, J. B., Seubert, P., Tsuang, D. W., Peskind, E. R. & Yu, C. E., Mar 2011, In : Neurobiology of Aging. 32, 3

Research output: Contribution to journalArticle

Cerebrospinal Fluid Proteins
Amyloid beta-Protein Precursor
Amyloid
Alzheimer Disease
Genes
45 Citations (Scopus)

Assessment of cognition in mild cognitive impairment: A comparative study

Snyder, P. J., Jackson, C. E., Petersen, R. C., Khachaturian, A. S., Kaye, J., Albert, M. S. & Weintraub, S., May 2011, In : Alzheimer's and Dementia. 7, 3, p. 338-355 18 p.

Research output: Contribution to journalArticle

Cognition
Alzheimer Disease
Decision Trees
Clinical Trials
Guidelines
1085 Citations (Scopus)

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Naj, A. C., Jun, G., Beecham, G. W., Wang, L. S., Vardarajan, B. N., Buros, J., Gallins, P. J., Buxbaum, J. D., Jarvik, G. P., Crane, P. K., Larson, E. B., Bird, T. D., Boeve, B. F., Graff-Radford, N. R., De Jager, P. L., Evans, D., Schneider, J. A., Carrasquillo, M. M., Ertekin-Taner, N., Younkin, S. G. & 135 others, Cruchaga, C., Kauwe, J. S. K., Nowotny, P., Kramer, P., Hardy, J., Huentelman, M. J., Myers, A. J., Barmada, M. M., Demirci, F. Y., Baldwin, C. T., Green, R. C., Rogaeva, E., George-Hyslop, P. S., Arnold, S. E., Barber, R., Beach, T., Bigio, E. H., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cotman, C. W., Cummings, J. L., Decarli, C., Dekosky, S. T., Diaz-Arrastia, R., Dick, M., Dickson, D. W., Ellis, W. G., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Giordani, B., Glass, J. D., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jicha, G. A., Jin, L. W., Johnson, N., Karlawish, J., Karydas, A., Kaye, J., Kim, R., Koo, E. H., Kowall, N. W., Lah, J. J., Levey, A. I., Lieberman, A. P., Lopez, O. L., MacK, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Parisi, J. E., Perl, D. P., Peskind, E., Petersen, R. C., Poon, W. W., Quinn, J., Rajbhandary, R. A., Raskind, M., Reisberg, B., Ringman, J. M., Roberson, E. D., Rosenberg, R. N., Sano, M., Schneider, L. S., Seeley, W., Shelanski, M. L., Slifer, M. A., Smith, C. D., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. R., Cantwell, L. B., Dombroski, B. A., Beekly, D., Lunetta, K. L., Martin, E. R., Kamboh, M. I., Saykin, A. J., Reiman, E. M., Bennett, D. A., Morris, J. C., Montine, T. J., Goate, A. M., Blacker, D., Tsuang, D. W., Hakonarson, H., Kukull, W. A., Foroud, T. M., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A. & Schellenberg, G. D., May 2011, In : Nature Genetics. 43, 5, p. 436-443 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Meta-Analysis
Genome-Wide Association Study
Disease Susceptibility
Genome
95 Citations (Scopus)

Ecology of the aging human brain

Sonnen, J. A., Santa Cruz, K., Hemmy, L. S., Woltjer, R. R., Leverenz, J. B., Montine, K. S., Jack, C. R., Kaye, J., Lim, K., Larson, E. B., White, L. & Montine, T. J., Aug 2011, In : Archives of Neurology. 68, 8, p. 1049-1056 8 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Ecology
Neurofibrillary Tangles
Amyloid Plaques
Cerebrovascular Trauma
31 Citations (Scopus)

Executive function predicts risk of falls in older adults without balance impairment

Buracchio, T. J., Mattek, N. C., Dodge, H., Hayes, T. L., Pavel, M., Howieson, D. & Kaye, J., 2011, In : BMC Geriatrics. 11, 74.

Research output: Contribution to journalArticle

Executive Function
Independent Living
Health
Neurologic Examination
Statistical Models
7 Citations (Scopus)

Gender effects on plasma and brain copper

Quinn, J., Harris, C., Kaye, J., Lind, B., Carter, R., Anekonda, T. & Ralle, M., 2011, In : International Journal of Alzheimer's Disease. 150916.

Research output: Contribution to journalArticle

Copper
Brain
Cerebrospinal Fluid
Healthy Volunteers
Serum
72 Citations (Scopus)

Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration

Chen-Plotkin, A. S., Martinez-Lage, M., Sleiman, P. M. A., Hu, W., Greene, R., Wood, E. M., Bing, S., Grossman, M., Schellenberg, G. D., Hatanpaa, K. J., Weiner, M. F., White, C. L., Brooks, W. S., Halliday, G. M., Kril, J. J., Gearing, M., Beach, T. G., Graff-Radford, N. R., Dickson, D. W., Rademakers, R. & 35 others, Boeve, B. F., Pickering-Brown, S. M., Snowden, J., Van Swieten, J. C., Heutink, P., Seelaar, H., Murrell, J. R., Ghetti, B., Spina, S., Grafman, J., Kaye, J., Woltjer, R. R., Mesulam, M., Bigio, E., Lladó, A., Miller, B. L., Alzualde, A., Moreno, F., Rohrer, J. D., Mackenzie, I. R. A., Feldman, H. H., Hamilton, R. L., Cruts, M., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Bird, T. D., Cairns, N. J., Goate, A., Frosch, M. P., Riederer, P. F., Bogdanovic, N., Lee, V. M. Y., Trojanowski, J. Q. & Van Deerlin, V. M., Apr 2011, In : Archives of Neurology. 68, 4, p. 488-497 10 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Mutation
Degeneration
Age of Onset
Chromosomes, Human, Pair 17
123 Citations (Scopus)

Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease

Perrin, R. J., Craig-Schapiro, R., Malone, J. P., Shah, A. R., Gilmore, P., Davis, A. E., Roe, C. M., Peskind, E. R., Li, G., Galasko, D. R., Clark, C. M., Quinn, J., Kaye, J., Morris, J. C., Holtzman, D. M., Townsend, R. & Fagan, A. M., 2011, In : PLoS One. 6, 1, e16032.

Research output: Contribution to journalArticle

Cerebrospinal fluid
dementia
Biomarkers
cerebrospinal fluid
Alzheimer disease
132 Citations (Scopus)

Intelligent Systems For Assessing Aging Changes: home-based, unobtrusive, and continuous assessment of aging.

Kaye, J., Maxwell, S. A., Mattek, N., Hayes, T. L., Dodge, H., Pavel, M., Jimison, H. B., Wild, K., Boise, L. & Zitzelberger, T. A., Jul 2011, In : Journals of Gerontology - Series B Psychological Sciences and Social Sciences. 66 Suppl 1

Research output: Contribution to journalArticle

Biomedical Technology Assessment
technology assessment
Physical Examination
Cohort Studies
community
1 Citation (Scopus)

Kernels for longitudinal data with variable sequence length and sampling intervals

Lu, Z., Leen, T. K. & Kaye, J., Sep 2011, In : Neural Computation. 23, 9, p. 2390-2420 31 p.

Research output: Contribution to journalArticle

Neuropsychological Tests
Cognitive Dysfunction
Length
Sampling
Classifier
7 Citations (Scopus)
Norovirus
Retirement
Quarantine
Health
Sensors