Jeffrey Kaye

Professor

  • 31755 Citations
  • 91 h-Index
1976 …2020

Research output per year

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Research Output

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Article
3 Scopus citations

Delays in the diagnosis of dementia: Perspectives of family caregivers

Boise, L., Morgan, D. L., Kaye, J. & Camicioli, R., Jan 1999, In : American Journal of Alzheimer's Disease and Other Dementias. 14, 1, p. 20-26 7 p.

Research output: Contribution to journalArticle

59 Scopus citations

Dementia assessment in primary care: Results from a study in three managed care systems

Boise, L., Neal, M. B. & Kaye, J., Jun 2004, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 59, 6, p. 621-626 6 p.

Research output: Contribution to journalArticle

Open Access
93 Scopus citations

Dementia Care Comes Home: Patient and Caregiver Assessment via Telemedicine

Lindauer, A., Seelye, A., Lyons, B., Dodge, H., Mattek, N., Mincks, K., Kaye, J. & Erten-Lyons, D., Oct 1 2017, In : Gerontologist. 57, 5, p. e85-e93

Research output: Contribution to journalArticle

19 Scopus citations

Dementia in down’s syndrome: Cerebral glucose utilization, neuropsychological assessment, and neuropathology

Schapiro, M. B., Ball, M. J., Grady, C. L., Haxby, J. V., Kaye, J. A. & Rapoport, S. I., Jun 1988, In : Neurology. 38, 6, p. 938-942 5 p.

Research output: Contribution to journalArticle

36 Scopus citations

Dementia in rural primary care practices in Lake County, Oregon

Camicioli, R., Willert, P., Lear, J., Grossmann, S., Kaye, J. & Butterfield, P., Jan 1 2000, In : Journal of Geriatric Psychiatry and Neurology. 13, 2, p. 87-92 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Dementia specialists and early adoption of amyloid imaging

Klein, E. P. & Kaye, J., Jan 1 2013, In : Journal of Alzheimer's Disease. 33, 2, p. 445-450 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Developing dementia prevention trials: Baseline report of the home-based assessment study

Sano, M., Egelko, S., Donohue, M., Ferris, S., Kaye, J., Hayes, T. L., Mundt, J. C., Sun, C. K., Paparello, S. & Aisen, P. S., Oct 1 2013, In : Alzheimer Disease and Associated Disorders. 27, 4, p. 356-362 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Diagnostic challenges in dementia

Kaye, J. A., Aug 5 1998, In : Neurology. 51, 1 SUPPL., p. S45-S52

Research output: Contribution to journalArticle

45 Scopus citations

Differential loss of synaptic proteins in Alzheimer's disease: Implications for synaptic dysfunction

Reddy, P. H., Mani, G., Park, B. S., Jacques, J., Murdoch, G., Whetsell, W., Kaye, J. & Manczak, M., Jan 1 2005, In : Journal of Alzheimer's Disease. 7, 2, p. 103-117 15 p.

Research output: Contribution to journalArticle

233 Scopus citations

Dyslipidemia and blood-brain barrier integrity in Alzheimer's disease

Bowman, G. L., Kaye, J. A. & Quinn, J. F., 2012, In : Current Gerontology and Geriatrics Research. 2012, 184042.

Research output: Contribution to journalArticle

39 Scopus citations

Early diagnosis of Alzheimer's disease and mild cognitive impairment: Imaging, biomarkers, and technology

Buracchio, T. & Kaye, J., Apr 1 2009, In : Generations. 33, 1, p. 18-23 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
23 Scopus citations

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature communications. 7, 11934.

Research output: Contribution to journalArticle

284 Scopus citations

Ecology of the aging human brain

Sonnen, J. A., Santa Cruz, K., Hemmy, L. S., Woltjer, R., Leverenz, J. B., Montine, K. S., Jack, C. R., Kaye, J., Lim, K., Larson, E. B., White, L. & Montine, T. J., Aug 2011, In : Archives of Neurology. 68, 8, p. 1049-1056 8 p.

Research output: Contribution to journalArticle

100 Scopus citations

Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease: A Randomized Clinical Trial

Van Dyck, C. H., Nygaard, H. B., Chen, K., Donohue, M. C., Raman, R., Rissman, R. A., Brewer, J. B., Koeppe, R. A., Chow, T. W., Rafii, M. S., Gessert, D., Choi, J., Turner, R. S., Kaye, J., Gale, S. A., Reiman, E. M., Aisen, P. S. & Strittmatter, S. M., Jan 1 2019, In : JAMA Neurology.

Research output: Contribution to journalArticle

9 Scopus citations

Effect of extrapyramidal signs and Lewy Bodies on survival in patients with Alzheimer disease

Haan, M. N., Jagust, W. J., Galasko, D. & Kaye, J., Jan 1 2002, In : Archives of Neurology. 59, 4, p. 588-593 6 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Effects of a γ-secretase inhibitor in a randomized study of patients with Alzheimer disease

Siemers, E. R., Quinn, J. F., Kaye, J., Farlow, M. R., Porsteinsson, A., Tariot, P., Zoulnouni, P., Galvin, J. E., Holtzman, D. M., Knopman, D. S., Satterwhite, J., Gonzales, C., Dean, R. A. & May, P. C., Feb 1 2006, In : Neurology. 66, 4, p. 602-604 3 p.

Research output: Contribution to journalArticle

274 Scopus citations

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: A genome-wide association study

Alzheimer Disease Genetics Consortium, Nov 1 2014, In : JAMA Neurology. 71, 11, p. 1394-1404 11 p.

Research output: Contribution to journalArticle

93 Scopus citations

Electrophysiologic function in the healthy, extremely old

Oken, B. S. & Kaye, J. A., Mar 1992, In : Neurology. 42, 3, p. 519-526 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Embedded Online Questionnaire Measures Are Sensitive to Identifying Mild Cognitive Impairment

Seelye, A., Mattek, N., Howieson, D., Austin, D., Wild, K., Dodge, H. & Kaye, J., 2016, In : Alzheimer Disease and Associated Disorders. 30, 2, p. 152-159 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient

Lerenz, J. B., Hamilton, R., Tsuang, D. W., Schantz, A., Vavrek, D., Larson, E. B., Kukull, W. A., Lopez, O., Galasko, D., Masliah, E., Kaye, J., Woltjer, R., Clark, C., Trojanowski, J. Q. & Montine, T. J., Apr 1 2008, In : Brain Pathology. 18, 2, p. 220-224 5 p.

Research output: Contribution to journalArticle

79 Scopus citations

Evidence for a role of the rare p.A152T variant in mapt in increasing the risk for FTD-spectrum and Alzheimer's diseases

Coppola, G., Chinnathambi, S., Lee, J. J. Y., Dombroski, B. A., Baker, M. C., Soto-ortolaza, A. I., Lee, S. E., Klein, E., Huang, A. Y., Sears, R., Lane, J. R., Karydas, A. M., Kenet, R. O., Biernat, J., Wang, L. S., Cotman, C. W., Decarli, C. S., Levey, A. I., Ringman, J. M., Mendez, M. F. & 210 others, Chui, H. C., Le ber, I., Brice, A., Lupton, M. K., Preza, E., Lovestone, S., Powell, J., Graff-radford, N., Petersen, R. C., Boeve, B. F., Lippa, C. F., Bigio, E. H., Mackenzie, I., Finger, E., Kertesz, A., Caselli, R. J., Gearing, M., Juncos, J. L., Ghetti, B., Spina, S., Bordelon, Y. M., Tourtellotte, W. W., Frosch, M. P., Vonsattel, J. P. G., Zarow, C., Beach, T. G., Albin, R. L., Lieberman, A. P., Lee, V. M., Trojanowski, J. Q., Van deerlin, V. M., Bird, T. D., Galasko, D. R., Masliah, E., White, C. L., Troncoso, J. C., Hannequin, D., Boxer, A. L., Geschwind, M. D., Kumar, S., Mandelkow, E. M., Wszolek, Z. K., Uitti, R. J., Dickson, D. W., Haines, J. L., Mayeux, R., Pericak-vance, M. A., Farrer, L. A., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barmada, M. M., Beach, T., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buros, J., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cotman, C. W., Crane, P. K., Cruchaga, C., Cummings, J. L., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Diaz-Arrastia, R., Dick, M., Dickson, D. W., Dombroski, B. A., Duara, R., Ellis, W. G., Ertekin-Taner, N. N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gallins, P. J., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Giordani, B., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Johnson, N., Jun, G., Kamboh, M. I., Karlawish, J., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, P., Kukull, W. A., Lah, J. J., Larson, E. B., Levey, A. I., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Myers, A. J., Naj, A. C., Nowotny, P., Parisi, J. E., Perl, D. P., Peskind, E., Petersen, R. C., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Rajbhandary, R. A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W., Shelanski, M. L., Slifer, M. A., Smith, C. D., Sonnen, J. A., Spina, S., George-Hyslop, P. S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Younkin, S. G., Ross, O. A., Rademakers, R., Schellenberg, G. D., Miller, B. L., Mandelkow, E. & Geschwind, D. H., Aug 2012, In : Human molecular genetics. 21, 15, p. 3500-3512 13 p.

Research output: Contribution to journalArticle

142 Scopus citations

Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease

Payami, H., Schellenberg, G. D., Zareparsi, S., Kaye, J., Sexton, G. J., Head, M. A., Matsuyama, S. S., Jarvik, L. F., Miller, B., McManus, D. Q., Bird, T. D., Katzman, R., Heston, L., Norman, D. & Small, G. W., Aug 1997, In : Neurology. 49, 2, p. 512-518 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

Evidence for familial factors that protect against dementia and outweigh the effect of increasing age

Payami, H., Montee, K. & Kaye, J., Mar 31 1994, In : American Journal of Human Genetics. 54, 4, p. 650-657 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Exceptional brain aging in a rural population-based cohort

Kaye, J., Michael, Y., Calvert, J., Leahy, M., Crawford, D. & Kramer, P., Jun 1 2009, In : Journal of Rural Health. 25, 3, p. 320-325 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Executive function predicts risk of falls in older adults without balance impairment

Buracchio, T. J., Mattek, N. C., Dodge, H. H., Hayes, T. L., Pavel, M., Howieson, D. B. & Kaye, J. A., Nov 10 2011, In : BMC Geriatrics. 11, 74.

Research output: Contribution to journalArticle

34 Scopus citations

Factors associated with brain donation among optimally healthy elderly people

Kaye, J. A., Dame, A., Lehman, S. & Sexton, G., Nov 1999, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 54, 11, p. M560-M564

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Factors associated with resistance to dementia despite high Alzheimer disease pathology

Erten-Lyons, D., Woltjer, R. L., Dodge, H., Nixon, R., Vorobik, R., Calvert, J. F., Leahy, M., Montine, T. & Kaye, J., Jan 27 2009, In : Neurology. 72, 4, p. 354-360 7 p.

Research output: Contribution to journalArticle

99 Scopus citations

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Alzheimer's Disease Neuroimaging Initiative, May 19 2015, In : Nature communications. 6, 6760.

Research output: Contribution to journalArticle

111 Scopus citations

Gait velocity estimation using time-interleaved between consecutive passive IR Sensor Activations

Rana, R., Austin, D., Jacobs, P., Karunanithi, M. & Kaye, J., Aug 1 2016, In : IEEE Sensors Journal. 16, 16, p. 6351-6358 8 p., 7486123.

Research output: Contribution to journalArticle

7 Scopus citations

GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology

Tsuang, D., Leverenz, J. B., Lopez, O. L., Hamilton, R. L., Bennett, D. A., Schneider, J. A., Buchman, A. S., Larson, E. B., Crane, P. K., Kaye, J. A., Kramer, P., Woltjer, R., Kukull, W., Nelson, P. T., Jicha, G. A., Neltner, J. H., Galasko, D., Masliah, E., Trojanowski, J. Q., Schellenberg, G. D. & 8 others, Yearout, D., Huston, H., Fritts-Penniman, A., Mata, I. F., Wan, J. Y., Edwards, K. L., Montine, T. J. & Zabetian, C. P., Nov 6 2012, In : Neurology. 79, 19, p. 1944-1950 7 p.

Research output: Contribution to journalArticle

90 Scopus citations

Gender difference in apolipoprotein E - associated risk for familial alzheimer disease: A possible clue to the higher incidence of alzheimer disease in women

Payami, H., Zareparsi, S., Montee, K. R., Sexton, G. J., Kaye, J. A., Bird, T. D., Yu, C. E., Wijsman, E. M., Heston, L. L., Litt, M. & Schellenberg, G. D., Dec 1 1996, In : American Journal of Human Genetics. 58, 4, p. 803-811 9 p.

Research output: Contribution to journalArticle

198 Scopus citations

Gender effects on plasma and brain copper

Quinn, J. F., Harris, C., Kaye, J. A., Lind, B., Carter, R., Anekonda, T. & Ralle, M., 2011, In : International Journal of Alzheimer's Disease. 150916.

Research output: Contribution to journalArticle

10 Scopus citations

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, Jan 1 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

Research output: Contribution to journalArticle

Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators & Alzheimer's Disease Genetics Consortium, Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration

Chen-Plotkin, A. S., Martinez-Lage, M., Sleiman, P. M. A., Hu, W., Greene, R., Wood, E. M. C., Bing, S., Grossman, M., Schellenberg, G. D., Hatanpaa, K. J., Weiner, M. F., White, C. L., Brooks, W. S., Halliday, G. M., Kril, J. J., Gearing, M., Beach, T. G., Graff-Radford, N. R., Dickson, D. W., Rademakers, R. & 35 others, Boeve, B. F., Pickering-Brown, S. M., Snowden, J., Van Swieten, J. C., Heutink, P., Seelaar, H., Murrell, J. R., Ghetti, B., Spina, S., Grafman, J., Kaye, J. A., Woltjer, R. L., Mesulam, M., Bigio, E., Lladó, A., Miller, B. L., Alzualde, A., Moreno, F., Rohrer, J. D., Mackenzie, I. R. A., Feldman, H. H., Hamilton, R. L., Cruts, M., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Bird, T. D., Cairns, N. J., Goate, A., Frosch, M. P., Riederer, P. F., Bogdanovic, N., Lee, V. M. Y., Trojanowski, J. Q. & Van Deerlin, V. M., Apr 1 2011, In : Archives of Neurology. 68, 4, p. 488-497 10 p.

Research output: Contribution to journalArticle

76 Scopus citations

Genetic anticipation in parkinson's disease

Payami, H., Bernard, S., Larsen, K., Kaye, J. & Nutt, J., Jan 1995, In : Neurology. 45, 1, p. 135-138 4 p.

Research output: Contribution to journalArticle

57 Scopus citations

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In : Nature genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

172 Scopus citations

Ginkgo biloba prevention trials: More than an ounce of prevention learned

Kaye, J., May 1 2009, In : Archives of Neurology. 66, 5, p. 652-654 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Greater orbital prefrontal volume selectively predicts worse working memory performance in older adults

Salat, D. H., Kaye, J. A. & Janowsky, J. S., 2002, In : Cerebral Cortex. 12, 5, p. 494-505 12 p.

Research output: Contribution to journalArticle

Open Access
89 Scopus citations

High cerebrospinal fluid tau and low amyloid β42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype

Galasko, D., Chang, L., Motter, R., Clark, C. M., Kaye, J., Knopman, D., Thomas, R., Kholodenko, D., Schenk, D., Lieberburg, I., Miller, B., Green, R., Basherad, R., Kertiles, L., Boss, M. A. & Seubert, P., Jul 1 1998, In : Archives of Neurology. 55, 7, p. 937-945 9 p.

Research output: Contribution to journalArticle

391 Scopus citations

Hippocampal Volume Is Associated with Memory but not Nonmemory Cognitive Performance in Patients with Mild Cognitive Impairment

Grundman, M., Jack, C. R., Petersen, R. C., Kim, H. T., Taylor, C., Datvian, M., Weiner, M. F., DeCarli, C., DeKosky, S. J., Van Dyck, C., Darvesh, S., Yaffe, K., Kaye, J., Ferris, S. H., Thomas, R. G. & Thal, L. J., Dec 1 2003, In : Journal of Molecular Neuroscience. 20, 3, p. 241-248 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

HLA-A2, or a closely linked gene, confers susceptibility to early-onset sporadic alzheimer’s disease in mene

Payami, H., Kaye, J., Becker, W., Norman, D. & Wetzsteon, P., Oct 1991, In : Neurology. 41, 10, p. 1544-1548 5 p.

Research output: Contribution to journalArticle

32 Scopus citations

HLA-A2 homozygosity but not heterozygosity is associated with Alzheimer disease

Zareparsi, S., James, D. M., Kaye, J. A., Bird, T. D., Schellenberg, G. D. & Payami, H., Mar 26 2002, In : Neurology. 58, 6, p. 973-975 3 p.

Research output: Contribution to journalArticle

22 Scopus citations

ICC-dementia (International Centenarian Consortium - dementia): An international consortium to determine the prevalence and incidence of dementia in centenarians across diverse ethnoracial and sociocultural groups

Brodaty, H., Woolf, C., Andersen, S., Barzilai, N., Brayne, C., Cheung, K. S. L., Corrada, M. M., Crawford, J. D., Daly, C., Gondo, Y., Hagberg, B., Hirose, N., Holstege, H., Kawas, C., Kaye, J., Kochan, N. A., Lau, B. H. P., Lucca, U., Marcon, G., Martin, P. & 10 others, Poon, L. W., Richmond, R., Robine, J. M., Skoog, I., Slavin, M. J., Szewieczek, J., Tettamanti, M., Viña, J., Perls, T. & Sachdev, P. S., Apr 21 2016, In : BMC Neurology. 16, 1, 52.

Research output: Contribution to journalArticle

12 Scopus citations

Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease

Perrin, R. J., Craig-Schapiro, R., Malone, J. P., Shah, A. R., Gilmore, P., Davis, A. E., Roe, C. M., Peskind, E. R., Li, G., Galasko, D. R., Clark, C. M., Quinn, J. F., Kaye, J. A., Morris, J. C., Holtzman, D. M., Townsend, R. & Fagan, A. M., 2011, In : PloS one. 6, 1, e16032.

Research output: Contribution to journalArticle

Open Access
129 Scopus citations

Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline

Silbert, L. C., Nelson, C., Howieson, D. B., Moore, M. M. & Kaye, J. A., Jul 8 2008, In : Neurology. 71, 2, p. 108-113 6 p.

Research output: Contribution to journalArticle

158 Scopus citations