Jeffrey Iliff

Associate Professor

  • 5886 Citations
  • 27 h-Index
20032020

Research output per year

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Research Output

  • 5886 Citations
  • 27 h-Index
  • 44 Article
  • 5 Review article
  • 2 Comment/debate
  • 1 Chapter
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Article
2019

Analysis of convective and diffusive transport in the brain interstitium

Ray, L., Iliff, J. J. & Heys, J. J., Mar 6 2019, In : Fluids and Barriers of the CNS. 16, 1, 6.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
Open Access
1 Scopus citations

Pericyte constriction underlies capillary derecruitment during hyperemia in the setting of arterial stenosis

Methner, C., Mishra, A., Golgotiu, K., Li, Y., Wei, W., Yanez, N., Zlokovic, B., Wang, R. K., Alkayed, N., Kaul, S. & Iliff, J., Aug 1 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 317, 2, p. H255-H263

Research output: Contribution to journalArticle

1 Scopus citations

Rebuttal from Matthew Simon and Jeffrey Iliff

Simon, M. & Iliff, J., Sep 1 2019, In : Journal of Physiology. 597, 17, p. 4425-4426 2 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Aquaporin-4-dependent glymphatic solute transport in the rodent brain

Mestre, H., Hablitz, L. M., Xavier, A. L. R., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Rivera, R. M. C., Simon, M. J., Pike, M. M., Plá, V., Du, T., Kress, B. T., Wang, X., Plog, B. A., Thrane, A. S., Lundgaard, I., Abe, Y., Yasui, M. & 6 others, Thomas, J. H., Xiao, M., Hirase, H., Asokan, A., Iliff, J. J. & Nedergaard, M., Dec 1 2018, In : eLife. 7, e40070.

Research output: Contribution to journalArticle

39 Scopus citations

Characterization of dural sinus-associated lymphatic vasculature in human Alzheimer's dementia subjects

Goodman, J. R., Adham, Z. O., Woltjer, R. R., Lund, A. & Iliff, J., Jan 1 2018, (Accepted/In press) In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

9 Scopus citations
8 Scopus citations
2 Scopus citations

Transcriptional network analysis of human astrocytic endfoot genes reveals region-specific associations with dementia status and tau pathology

Simon, M. J., Wang, M. X., Murchison, C. F., Roese, N. E., Boespflug, E., Woltjer, R. R. & Iliff, J., Dec 1 2018, In : Scientific Reports. 8, 1, 12389.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Association of perivascular localization of aquaporin-4 with cognition and Alzheimer disease in aging brains

Zeppenfeld, D. M., Simon, M., Haswell, J. D., D'Abreo, D., Murchison, C., Quinn, J., Grafe, M., Woltjer, R. R., Kaye, J. & Iliff, J., Jan 1 2017, In : JAMA Neurology. 74, 1, p. 91-99 9 p.

Research output: Contribution to journalArticle

73 Scopus citations

A transcriptome-based assessment of the astrocytic dystrophin-associated complex in the developing human brain

Simon, M. J., Murchison, C. & Iliff, J., 2017, (Accepted/In press) In : Journal of Neuroscience Research.

Research output: Contribution to journalArticle

4 Scopus citations

Focal solute trapping and global glymphatic pathway impairment in a murine model of multiple microinfarcts

Wang, M., Ding, F., Deng, S. Y., Guo, X., Wang, W., Iliff, J. J. & Nedergaard, M., Mar 15 2017, In : Journal of Neuroscience. 37, 11, p. 2870-2877 8 p.

Research output: Contribution to journalArticle

38 Scopus citations
22 Scopus citations
30 Scopus citations
2016

Methamphetamine induces the release of endothelin

Seo, J. W., Jones, S. M., Hostetter, T. A., Iliff, J. & West, G. A., Feb 1 2016, In : Journal of Neuroscience Research. 94, 2, p. 170-178 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
87 Scopus citations
2014

A novel technique for morphometric quantification of subarachnoid hemorrhage-induced microglia activation

Plog, B. A., Moll, K. M., Kang, H., Iliff, J. J., Dashnaw, M. L., Nedergaard, M. & Vates, G. E., May 30 2014, In : Journal of Neuroscience Methods. 229, p. 44-52 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effects of traumatic brain injury on reactive astrogliosis and seizures in mouse models of Alexander disease

Cotrina, M. L., Chen, M., Han, X., Iliff, J., Ren, Z., Sun, W., Hagemann, T., Goldman, J., Messing, A. & Nedergaard, M., Sep 25 2014, In : Brain research. 1582, p. 211-219 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury

Iliff, J. J., Chen, M. J., Plog, B. A., Zeppenfeld, D. M., Soltero, M., Yang, L., Singh, I., Deane, R. & Nedergaard, M., Dec 3 2014, In : Journal of Neuroscience. 34, 49, p. 16180-16193 14 p.

Research output: Contribution to journalArticle

287 Scopus citations

Impairment of paravascular clearance pathways in the aging brain

Kress, B. T., Iliff, J. J., Xia, M., Wang, M., Wei Bs, H. S., Zeppenfeld, D., Xie, L., Hongyi Kang, B. S., Xu, Q., Liew, J. A., Plog, B. A., Ding, F., PhD, R. D. & Nedergaard, M., Dec 1 2014, In : Annals of Neurology. 76, 6, p. 845-861 17 p.

Research output: Contribution to journalArticle

329 Scopus citations

The pathophysiology underlying repetitive mild traumatic brain injury in a novel mouse model of chronic traumatic encephalopathy

Petraglia, A., Plog, B., Dayawansa, S., Dashnaw, M., Czerniecka, K., Walker, C., Chen, M., Hyrien, O., Iliff, J., Deane, R., Huang, J. & Nedergaard, M., Jan 1 2014, In : Surgical Neurology International. 5, 1

Research output: Contribution to journalArticle

70 Scopus citations

The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: A novel mouse model of chronic traumatic encephalopathy

Petraglia, A. L., Plog, B. A., Dayawansa, S., Chen, M., Dashnaw, M. L., Czerniecka, K., Walker, C. T., Viterise, T., Hyrien, O., Iliff, J. J., Deane, R., Nedergaard, M. & Huang, J. H., Jul 1 2014, In : Journal of neurotrauma. 31, 13, p. 1211-1224 14 p.

Research output: Contribution to journalArticle

109 Scopus citations
2013

Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

Iliff, J. J., Lee, H., Yu, M., Feng, T., Logan, J., Nedergaard, M. & Benveniste, H., Mar 1 2013, In : Journal of Clinical Investigation. 123, 3, p. 1299-1309 11 p.

Research output: Contribution to journalArticle

348 Scopus citations

Cerebral arterial pulsation drives paravascular CSF-Interstitial fluid exchange in the murine brain

Iliff, J. J., Wang, M., Zeppenfeld, D. M., Venkataraman, A., Plog, B. A., Liao, Y., Deane, R. & Nedergaard, M., Nov 15 2013, In : Journal of Neuroscience. 33, 46, p. 18190-18199 10 p.

Research output: Contribution to journalArticle

325 Scopus citations

Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer

Yang, L., Kress, B. T., Weber, H. J., Thiyagarajan, M., Wang, B., Deane, R., Benveniste, H., Iliff, J. J. & Nedergaard, M., May 1 2013, In : Journal of translational medicine. 11, 1, 107.

Research output: Contribution to journalArticle

142 Scopus citations

'Hit & Run' model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation

Ren, Z., Iliff, J. J., Yang, L., Yang, J., Chen, X., Chen, M. J., Giese, R. N., Wang, B., Shi, X. & Nedergaard, M., Jun 1 2013, In : Journal of Cerebral Blood Flow and Metabolism. 33, 6, p. 834-845 12 p.

Research output: Contribution to journalArticle

104 Scopus citations

Is there a cerebral lymphatic system?

Iliff, J. J. & Nedergaard, M., Jan 1 2013, In : Stroke. 44, SUPPL. 1, p. S93-S95

Research output: Contribution to journalArticle

147 Scopus citations

Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain

Thrane, V. R., Thrane, A. S., Plog, B. A., Thiyagarajan, M., Iliff, J. J., Deane, R., Nagelhus, E. A. & Nedergaard, M., Sep 17 2013, In : Scientific Reports. 3, 2582.

Research output: Contribution to journalArticle

70 Scopus citations

Sleep drives metabolite clearance from the adult brain

Xie, L., Kang, H., Xu, Q., Chen, M. J., Liao, Y., Thiyagarajan, M., O'Donnell, J., Christensen, D. J., Nicholson, C., Iliff, J. J., Takano, T., Deane, R. & Nedergaard, M., Jan 1 2013, In : Science. 342, 6156, p. 373-377 5 p.

Research output: Contribution to journalArticle

1419 Scopus citations
2012

A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β

Iliff, J. J., Wang, M., Liao, Y., Plogg, B. A., Peng, W., Gundersen, G. A., Benveniste, H., Vates, G. E., Deane, R., Goldman, S. A., Nagelhus, E. A. & Nedergaard, M., Aug 15 2012, In : Science translational medicine. 4, 147, 147ra111.

Research output: Contribution to journalArticle

1391 Scopus citations

Cognitive deficits and delayed neuronal loss in a mouse model of multiple microinfarcts

Wang, M., Iliff, J. J., Liao, Y., Chen, M. J., Shinseki, M. S., Venkataraman, A., Cheung, J., Wang, W. & Nedergaard, M., Dec 12 2012, In : Journal of Neuroscience. 32, 50, p. 17948-17960 13 p.

Research output: Contribution to journalArticle

69 Scopus citations
2010
20 Scopus citations
2009
15 Scopus citations

Epoxyeicosanoids as mediators of neurogenic vasodilation in cerebral vessels

Iliff, J. J., Wang, R., Zeldin, D. C. & Alkayed, N. J., May 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 5, p. H1352-H1363

Research output: Contribution to journalArticle

54 Scopus citations

Role of soluble epoxide hydrolase in the sex-specific vascular response to cerebral ischemia

Zhang, W., Iliff, J. J., Campbell, C. J., Wang, R. K., Hurn, P. D. & Alkayed, N. J., Aug 1 2009, In : Journal of Cerebral Blood Flow and Metabolism. 29, 8, p. 1475-1481 7 p.

Research output: Contribution to journalArticle

54 Scopus citations
2008

In vivo cerebrovascular effects of cocaine- and amphetamine-regulated transcript (CART) peptide

Iliff, J. J., Alkayed, N. J., Golshani, K. J., Weinstein, J., Traystman, R. J. & West, G. A., Jul 1 2008, In : Journal of Cardiovascular Pharmacology. 52, 1, p. 82-89 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia.

Zhang, W., Otsuka, T., Sugo, N., Ardeshiri, A., Alhadid, Y. K., Iliff, J. J., DeBarber, A. E., Koop, D. R. & Alkayed, N. J., Jul 2008, In : Stroke; a journal of cerebral circulation. 39, 7, p. 2073-2078 6 p.

Research output: Contribution to journalArticle

142 Scopus citations

Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo

Motoki, A., Merkel, M. J., Packwood, W. H., Cao, Z., Liu, L., Iliff, J., Alkayed, N. J. & Van Winkle, D. M., Nov 1 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 295, 5, p. H2128-H2134

Research output: Contribution to journalArticle

80 Scopus citations
2007

A novel role for P450 eicosanoids in the neurogenic control of cerebral blood flow in the rat

Iliff, J. J., Close, L. N., Selden, N. R. & Alkayed, N. J., Jul 2007, In : Experimental physiology. 92, 4, p. 653-658 6 p.

Research output: Contribution to journalArticle

45 Scopus citations

Soluble epoxide hydrolase: Sex differences and role in estrogen-mediated neuroprotection

Zhang, W., Iliff, J. J., Alhadid, Y. K., Ardeshiri, A., Koerner, I. P., Hurn, P. D. & Alkayed, N. J., Nov 13 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, SUPPL. 1, p. BP37-03H

Research output: Contribution to journalArticle

2005

Cocaine- and amphetamine-regulated transcript (CART) peptide: A vasoactive role in the cerebral circulation

Iliff, J. J., Alkayed, N. J., Gloshani, K. J., Traystman, R. J. & West, G. A., Oct 1 2005, In : Journal of Cerebral Blood Flow and Metabolism. 25, 10, p. 1376-1385 10 p.

Research output: Contribution to journalArticle

20 Scopus citations
2003

Adenosine receptors mediate glutamate-evoked arteriolar dilation in the rat cerebral cortex

Iliff, J. J., D'Ambrosio, R., Ngai, A. C. & Winn, H. R., May 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 5 53-5, p. H1631-H1637

Research output: Contribution to journalArticle

44 Scopus citations