Jason Link

Research Assistant Professor

  • 571 Citations
  • 13 h-Index
20022020

Research output per year

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Research Output

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Article
2020

Acidic fibroblast growth factor underlies microenvironmental regulation of myc in pancreatic cancer

Bhattacharyya, S., Oon, C., Kothari, A., Horton, W., Link, J., Sears, R. C. & Sherman, M. H., Aug 3 2020, In : Journal of Experimental Medicine. 217, 8, e20191805.

Research output: Contribution to journalArticle

Open Access
2019

A stromal lysolipid–autotaxin signaling axis promotes pancreatic tumor progression

Auciello, F. R., Bulusu, V., Oon, C., Tait-Mulder, J., Berry, M., Bhattacharyya, S., Tumanov, S., Allen-Petersen, B. L., Link, J., Kendsersky, N. D., Vringer, E., Schug, M., Novo, D., Hwang, R. F., Evans, R. M., Nixon, C., Dorrell, C., Morton, J. P., Norman, J. C., Sears, R. C. & 2 others, Kamphorst, J. J. & Sherman, M. H., May 2019, In : Cancer discovery. 9, 5, p. 617-627 11 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations
2017

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Farrell, A. S., Joly, M. M., Allen-Petersen, B. L., Worth, P. J., Lanciault, C., Sauer, D., Link, J., Pelz, C., Heiser, L. M., Morton, J. P., Muthalagu, N., Hoffman, M. T., Manning, S. L., Pratt, E. D., Kendsersky, N. D., Egbukichi, N., Amery, T. S., Thoma, M. C., Jenny, Z. P., Rhim, A. D. & 5 others, Murphy, D. J., Sansom, O. J., Crawford, H. C., Sheppard, B. C. & Sears, R. C., Dec 1 2017, In : Nature communications. 8, 1, 1728.

Research output: Contribution to journalArticle

20 Scopus citations
2012

A critical role for Mnt in Myc-driven T-cell proliferation and oncogenesis

Link, J. M., Ota, S., Zhou, Z. Q., Daniel, C. J., Sears, R. C. & Hurlin, P. J., Nov 27 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 48, p. 19685-19690 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
2009

The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects

Ota, S., Zhou, Z. Q., Link, J. M. & Hurlin, P. J., 2009, In : Human molecular genetics. 18, 14, p. 2609-2621 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
2007

Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice

Link, J. M., Rich, C. M., Korat, M., Burrows, G. G., Offner, H. & Vandenbark, A. A., Apr 1 2007, In : Clinical Immunology. 123, 1, p. 95-104 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
2006

αB-Crystallin-reactive T cells from knockout mice are not encephalitogenic

Wang, C., Chou, Y. K., Rich, C. M., Link, J. M., Afentoulis, M. E., van Noort, J. M., Wawrousek, E. F., Offner, H. & Vandenbark, A. A., Jul 2006, In : Journal of Neuroimmunology. 176, 1-2, p. 51-62 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
2005

Adult lupus-prone MRL/MpJ2+ mice express a primary antibody repertoire that differs in CDR-H3 length distribution and hydrophobicity from that expressed in the C3H parental strain

Zemlin, M., Ippolito, G. C., Zemlin, C., Link, J., Monestier, M. & Schroeder, H. W., May 2005, In : Molecular Immunology. 42, 7, p. 789-798 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Despite extensive similarity in germline DH and JH sequence, the adult Rhesus macaque CDR-H3 repertoire differs from human

Link, J. M., Larson, J. E. & Schroeder, H. W., May 2005, In : Molecular Immunology. 42, 8, p. 943-955 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Identification of HLA-DRB1*1501-restricted T-cell epitopes from prostate-specific antigen

Klyushnenkova, E. N., Link, J., Oberle, W. T., Kodak, J., Rich, C., Vandenbark, A. A. & Alexander, R. B., Apr 15 2005, In : Clinical Cancer Research. 11, 8, p. 2853-2861 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Rationally designed mutations convert complexes of human recombinant T cell receptor ligands into monomers that retain biological activity

Huan, J. Y., Meza-Romero, R., Mooney, J. L., Chou, Y. K., Edwards, D. M., Rich, C., Link, J. M., Vandenbark, A. A., Bourdette, D. N., Bächinger, H. P. & Burrows, G., Jan 1 2005, In : Journal of Chemical Technology and Biotechnology. 80, 1, p. 2-12 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2004

HLA-DRB1*1501 risk association in multiple sclerosis may not be related to presentation of myelin epitopes

Finn, T. P., Jones, R. E., Rich, C., Dahan, R., Link, J., David, C. S., Chou, Y. K., Offner, H. & Vandenbark, A. A., Oct 1 2004, In : Journal of Neuroscience Research. 78, 1, p. 100-114 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Monomeric Recombinant TCR Ligand Reduces Relapse Rate and Severity of Experimental Autoimmune Encephalomyelitis in SJL/J Mice through Cytokine Switch

Huan, J., Subramanian, S., Jones, R., Rich, C., Link, J., Mooney, J., Bourdette, D. N., Vandenbark, A. A., Burrows, G. & Offner, H., Apr 1 2004, In : Journal of Immunology. 172, 7, p. 4556-4566 11 p.

Research output: Contribution to journalArticle

Open Access
43 Scopus citations

Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice

Rich, C., Link, J. M., Zamora, A., Jacobsen, H., Meza-Romero, R., Offner, H., Jones, R., Burrows, G., Fugger, L. & Vandenbark, A. A., May 1 2004, In : European Journal of Immunology. 34, 5, p. 1251-1261 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

T-cell hybridoma specific for myelin oligodendrocyte glycoprotein-35-55 peptide produced from HLA-DRB1*1501-transgenic mice

Chou, Y. K., Culbertson, N., Rich, C., LaTocha, D., Buenafe, A. C., Huan, J., Link, J., Wands, J. M., Born, W. K., Offner, H., Bourdette, D. N., Burrows, G. & Vandenbark, A. A., Sep 1 2004, In : Journal of Neuroscience Research. 77, 5, p. 670-680 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2003

Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures

Zemlin, M., Klinger, M., Link, J., Zemlin, C., Bauer, K., Engler, J. A., Schroeder, H. W. & Kirkham, P. M., Dec 5 2003, In : Journal of molecular biology. 334, 4, p. 733-749 17 p.

Research output: Contribution to journalArticle

224 Scopus citations
2002

Clues to the etiology of autoimmune diseases through analysis of immunoglobulin genes

Link, J. M. & Schroeder, H. W., Apr 9 2002, In : Arthritis Research. 4, 2, p. 80-83 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

The Rhesus monkey immunoglobulin IGHD and IGHJ germline repertoire

Link, J. M., Hellinger, M. A. & Schroeder, H. W., Aug 8 2002, In : Immunogenetics. 54, 4, p. 240-250 11 p.

Research output: Contribution to journalArticle

24 Scopus citations