Jason Link

Research Assistant Professor

  • 557 Citations
  • 13 h-Index
20022019

Research output per year

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Research Output

2019

A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression

Auciello, F. R., Bulusu, V., Oon, C., Tait-Mulder, J., Berry, M., Bhattacharyya, S., Tumanov, S., Allen-Petersen, B. L., Link, J., Kendsersky, N. D., Vringer, E., Schug, M., Novo, D., Hwang, R. F., Evans, R. M., Nixon, C., Dorrell, C., Morton, J. P., Norman, J. C., Sears, R. & 2 others, Kamphorst, J. J. & Sherman, M., May 1 2019, In : Cancer discovery. 9, 5, p. 617-627 11 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
2017

Deep learning based Nucleus Classification in pancreas histological images

Chang, Y. H., Thibault, G., Madin, O., Azimi, V., Meyers, C., Johnson, B., Link, J., Margolin, A. & Gray, J., Sep 13 2017, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., p. 672-675 4 p. 8036914

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Scopus citations

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Farrell, A. S., Joly, M. M., Allen-Petersen, B. L., Worth, P. J., Lanciault, C., Sauer, D., Link, J., Pelz, C., Heiser, L. M., Morton, J. P., Muthalagu, N., Hoffman, M. T., Manning, S. L., Pratt, E. D., Kendsersky, N. D., Egbukichi, N., Amery, T. S., Thoma, M. C., Jenny, Z. P., Rhim, A. D. & 5 others, Murphy, D. J., Sansom, O. J., Crawford, H. C., Sheppard, B. C. & Sears, R. C., Dec 1 2017, In : Nature communications. 8, 1, 1728.

Research output: Contribution to journalArticle

17 Scopus citations
2016

Quantitative analysis of histological tissue image based on cytological profiles and spatial statistics

Chang, Y. H., Thibault, G., Azimi, V., Johnson, B., Jorgens, D., Link, J., Margolin, A. & Gray, J., Oct 13 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., Vol. 2016-October. p. 1175-1178 4 p. 7590914

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations
2015

The activities of MYC, MNT and the MAX-interactome in lymphocyte proliferation and oncogenesis

Link, J. M. & Hurlin, P. J., May 1 2015, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1849, 5, p. 554-562 9 p.

Research output: Contribution to journalReview article

17 Scopus citations
2013

MYC needs MNT

Link, J. M. & Hurlin, P. J., Feb 1 2013, In : Cell Cycle. 12, 3, p. 385-386 2 p.

Research output: Contribution to journalEditorial

3 Scopus citations
2012

A critical role for Mnt in Myc-driven T-cell proliferation and oncogenesis

Link, J. M., Ota, S., Zhou, Z. Q., Daniel, C. J., Sears, R. C. & Hurlin, P. J., Nov 27 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 48, p. 19685-19690 6 p.

Research output: Contribution to journalArticle

16 Scopus citations
2009

The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects

Ota, S., Zhou, Z. Q., Link, J. M. & Hurlin, P. J., Jul 10 2009, In : Human molecular genetics. 18, 14, p. 2609-2621 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
2008

Erratum to "αB-Crystallin-reactive T cells from knockout mice are not encephalitogenic" [J. Neuroimmunol. 176 (2006) 51-62] (DOI:10.1016/j.jneuroim.2006.04.010)

Wang, C., Chou, Y. K., Rich, C. M., Link, J. M., Afentoulis, M. E., van Noort, J. M., Wawrousek, E. F., Offner, H. & Vandenbark, A. A., Dec 15 2008, In : Journal of Neuroimmunology. 205, 1-2, 1 p.

Research output: Contribution to journalComment/debate

2007

Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice

Link, J. M., Rich, C. M., Korat, M., Burrows, G. G., Offner, H. & Vandenbark, A. A., Apr 1 2007, In : Clinical Immunology. 123, 1, p. 95-104 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
2006

αB-Crystallin-reactive T cells from knockout mice are not encephalitogenic

Wang, C., Chou, Y. K., Rich, C. M., Link, J. M., Afentoulis, M. E., van Noort, J. M., Wawrousek, E. F., Offner, H. & Vandenbark, A. A., Jul 2006, In : Journal of Neuroimmunology. 176, 1-2, p. 51-62 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
2005

Adult lupus-prone MRL/MpJ2+ mice express a primary antibody repertoire that differs in CDR-H3 length distribution and hydrophobicity from that expressed in the C3H parental strain

Zemlin, M., Ippolito, G. C., Zemlin, C., Link, J., Monestier, M. & Schroeder, H. W., May 2005, In : Molecular Immunology. 42, 7, p. 789-798 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Despite extensive similarity in germline DH and JH sequence, the adult Rhesus macaque CDR-H3 repertoire differs from human

Link, J. M., Larson, J. E. & Schroeder, H. W., May 2005, In : Molecular Immunology. 42, 8, p. 943-955 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Identification of HLA-DRB1*1501-restricted T-cell epitopes from prostate-specific antigen

Klyushnenkova, E. N., Link, J., Oberle, W. T., Kodak, J., Rich, C., Vandenbark, A. A. & Alexander, R. B., Apr 15 2005, In : Clinical Cancer Research. 11, 8, p. 2853-2861 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Rationally designed mutations convert complexes of human recombinant T cell receptor ligands into monomers that retain biological activity

Huan, J. Y., Meza-Romero, R., Mooney, J. L., Chou, Y. K., Edwards, D. M., Rich, C., Link, J. M., Vandenbark, A. A., Bourdette, D. N., Bächinger, H. P. & Burrows, G. G., Jan 1 2005, In : Journal of Chemical Technology and Biotechnology. 80, 1, p. 2-12 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2004

HLA-DRB1*1501 risk association in multiple sclerosis may not be related to presentation of myelin epitopes

Finn, T. P., Jones, R. E., Rich, C., Dahan, R., Link, J., David, C. S., Chou, Y. K., Offner, H. & Vandenbark, A. A., Oct 1 2004, In : Journal of Neuroscience Research. 78, 1, p. 100-114 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Monomeric Recombinant TCR Ligand Reduces Relapse Rate and Severity of Experimental Autoimmune Encephalomyelitis in SJL/J Mice through Cytokine Switch

Huan, J., Subramanian, S., Jones, R., Rich, C., Link, J., Mooney, J., Bourdette, D. N., Vandenbark, A. A., Burrows, G. G. & Offner, H., Apr 1 2004, In : Journal of Immunology. 172, 7, p. 4556-4566 11 p.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations

Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice

Rich, C., Link, J. M., Zamora, A., Jacobsen, H., Meza-Romero, R., Offner, H., Jones, R., Burrows, G. G., Fugger, L. & Vandenbark, A. A., May 1 2004, In : European Journal of Immunology. 34, 5, p. 1251-1261 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

T-cell hybridoma specific for myelin oligodendrocyte glycoprotein-35-55 peptide produced from HLA-DRB1*1501-transgenic mice

Chou, Y. K., Culbertson, N., Rich, C., LaTocha, D., Buenafe, A. C., Huan, J., Link, J., Wands, J. M., Born, W. K., Offner, H., Bourdette, D. N., Burrows, G. G. & Vandenbark, A. A., Sep 1 2004, In : Journal of Neuroscience Research. 77, 5, p. 670-680 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2003

Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures

Zemlin, M., Klinger, M., Link, J., Zemlin, C., Bauer, K., Engler, J. A., Schroeder, H. W. & Kirkham, P. M., Dec 5 2003, In : Journal of molecular biology. 334, 4, p. 733-749 17 p.

Research output: Contribution to journalArticle

221 Scopus citations
2002

Clues to the etiology of autoimmune diseases through analysis of immunoglobulin genes

Link, J. M. & Schroeder, H. W., Apr 9 2002, In : Arthritis Research. 4, 2, p. 80-83 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

The Rhesus monkey immunoglobulin IGHD and IGHJ germline repertoire

Link, J. M., Hellinger, M. A. & Schroeder, H. W., Aug 8 2002, In : Immunogenetics. 54, 4, p. 240-250 11 p.

Research output: Contribution to journalArticle

24 Scopus citations