Janice Vranka

Research Assistant Professor

  • 1672 Citations
  • 19 h-Index
19962019

Research output per year

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Research Output

2019

GPR158 in the visual system: Homeostatic role in regulation of intraocular pressure

Itakura, T., Webster, A., Chintala, S. K., Wang, Y., Gonzalez, J. M., Tan, J. C., Vranka, J. A., Acott, T., Craft, C. M., Sibug Saber, M. E., Jeong, S., Stamer, W. D., Martemyanov, K. A. & Fini, M. E., May 2019, In : Journal of Ocular Pharmacology and Therapeutics. 35, 4, p. 203-215 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Biomechanical rigidity and quantitative proteomics analysis of segmental regions of the trabecular meshwork at physiologic and elevated pressures

Vranka, J. A., Staverosky, J. A., Reddy, A. P., Wilmarth, P. A., David, L. L., Acott, T. S., Russell, P. & Raghunathan, V. K., Jan 2018, In : Investigative Ophthalmology and Visual Science. 59, 1, p. 246-259 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Consensus recommendations for trabecular meshwork cell isolation, characterization and culture

Keller, K. E., Bhattacharya, S. K., Borrás, T., Brunner, T. M., Chansangpetch, S., Clark, A. F., Dismuke, W. M., Du, Y., Elliott, M. H., Ethier, C. R., Faralli, J. A., Freddo, T. F., Fuchshofer, R., Giovingo, M., Gong, H., Gonzalez, P., Huang, A., Johnstone, M. A., Kaufman, P. L., Kelley, M. J. & 37 others, Knepper, P. A., Kopczynski, C. C., Kuchtey, J. G., Kuchtey, R. W., Kuehn, M. H., Lieberman, R. L., Lin, S. C., Liton, P., Liu, Y., Lütjen-Drecoll, E., Mao, W., Masis-Solano, M., McDonnell, F., McDowell, C. M., Overby, D. R., Pattabiraman, P. P., Raghunathan, V. K., Rao, P. V., Rhee, D. J., Chowdhury, U. R., Russell, P., Samples, J. R., Schwartz, D., Stubbs, E. B., Tamm, E. R., Tan, J. C., Toris, C. B., Torrejon, K. Y., Vranka, J. A., Wirtz, M. K., Yorio, T., Zhang, J., Zode, G. S., Fautsch, M. P., Peters, D. M., Acott, T. S. & Stamer, W. D., Jun 2018, In : Experimental Eye Research. 171, p. 164-173 10 p.

Research output: Contribution to journalShort survey

46 Scopus citations

Glaucomatous cell derived matrices differentially modulate non-glaucomatous trabecular meshwork cellular behavior

Raghunathan, V. K., Benoit, J., Kasetti, R., Zode, G., Salemi, M., Phinney, B. S., Keller, K. E., Staverosky, J. A., Murphy, C. J., Acott, T. & Vranka, J., Apr 15 2018, In : Acta Biomaterialia. 71, p. 444-459 16 p.

Research output: Contribution to journalArticle

10 Scopus citations
2017

Estimating human trabecular meshwork stiffness by numerical modeling and advanced OCT imaging

Wang, K., Johnstone, M. A., Xin, C., Song, S., Padilla, S., Vranka, J. A., Acott, T. S., Zhou, K., Schwaner, S. A., Wang, R. K., Sulchek, T. & Ethier, C. R., Sep 2017, In : Investigative Ophthalmology and Visual Science. 58, 11, p. 4809-4817 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Pressure-induced expression changes in segmental flow regions of the human trabecular meshwork

Vranka, J. A. & Acott, T. S., May 1 2017, In : Experimental Eye Research. 158, p. 67-72 6 p.

Research output: Contribution to journalReview article

14 Scopus citations
2016

Bone matrix hypermineralization in prolyl-3 hydroxylase 1 deficient mice

Fratzl-Zelman, N., Bächinger, H. P., Vranka, J., Roschger, P., Klaushofer, K. & Rauch, F., Apr 1 2016, In : Bone. 85, p. 15-22 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015
113 Scopus citations
42 Scopus citations
2014

Biological role of prolyl 3-hydroxylation in type IV collagen

Pokidysheva, E., Boudko, S., Vranka, J., Zientek, K., Maddox, K., Moser, M., Fässler, R., Ware, J. & Bächinger, H. P., 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 1, p. 161-166 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Intraocular pressure homeostasis: Maintaining balance in a high-pressure environment

Acott, T. S., Kelley, M. J., Keller, K. E., Vranka, J. A., Abu-Hassan, D. W., Li, X., Aga, M. & Bradley, J. M., Mar 1 2014, In : Journal of Ocular Pharmacology and Therapeutics. 30, 2-3, p. 94-101 8 p.

Research output: Contribution to journalReview article

50 Scopus citations
2013

Posttranslational modifications in type I collagen from different tissues extracted from wild type and prolyl 3-hydroxylase 1 null mice

Pokidysheva, E., Zientek, K. D., Ishikawa, Y., Mizuno, K., Vranka, J. A., Montgomery, N. T., Keene, D. R., Kawaguchi, T., Okuyama, K. & Bächinger, H. P., Aug 23 2013, In : Journal of Biological Chemistry. 288, 34, p. 24742-24752 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

The effects of tenascin C knockdown on trabecular meshwork outflow resistance

Keller, K. E., Vranka, J. A., Haddadin, R. I., Kang, M. H., Oh, D. J., Rhee, D. J., Yang, Y. F., Sun, Y. Y., Kelley, M. J. & Acott, T. S., 2013, In : Investigative Ophthalmology and Visual Science. 54, 8, p. 5613-5623 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
2012

Inhibition of Hyaluronan Synthesis Reduces Versican and Fibronectin Levels in Trabecular Meshwork Cells

Keller, K. E., Sun, Y. Y., Vranka, J. A., Hayashi, L. & Acott, T. S., Nov 5 2012, In : PloS one. 7, 11, e48523.

Research output: Contribution to journalArticle

20 Scopus citations

Mutation in cyclophilin B that causes hyperelastosis cutis in american quarter horse does not affect peptidylprolyl cis-trans isomerase activity but shows altered cyclophilin b-protein interactions and affects collagen folding

Ishikawa, Y., Vranka, J. A., Boudko, S. P., Pokidysheva, E., Mizuno, K., Zientek, K., Keene, D. R., Rashmir-Raven, A. M., Nagata, K., Winand, N. J. & Bächinger, H. P., Jun 22 2012, In : Journal of Biological Chemistry. 287, 26, p. 22253-22265 13 p.

Research output: Contribution to journalArticle

58 Scopus citations
2011
65 Scopus citations
2010

Collagen formation and structure

Bächinger, H. P., Mizuno, K., Vranka, J. A. & Boudko, S. P., Mar 1 2010, Comprehensive Natural Products II: Chemistry and Biology. Elsevier Ltd, Vol. 5. p. 469-530 62 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

27 Scopus citations

Erratum: Prolyl 3-hydroxylase 1 null mice display abnormalities in fibrillar collagen-rich tissues such as tendons, skin, and bones (The Journal of Biological Chemistry (2010) 285, (17253-17262) DOI: 10.1074/jbc.A110.102228)

Vranka, J. A., Pokidysheva, E., Hayashi, L., Zientek, K., Mizuno, K., Ishikawa, Y., Maddox, K., Tufa, S., Keene, D. R., Klein, R. & Bachinger, H. P., Jun 25 2010, In : Journal of Biological Chemistry. 285, 26, 1 p.

Research output: Contribution to journalComment/debate

Prolyl 3-hydroxylase 1 null mice display abnormalities in fibrillar collagen-rich tissues such as tendons, skin, and bones

Vranka, J. A., Pokidysheva, E., Hayashi, L., Zientek, K., Mizuno, K., Ishikawa, Y., Maddox, K., Tufa, S., Keene, D. R., Klein, R. & Bächinger, H. P., May 28 2010, In : Journal of Biological Chemistry. 285, 22, p. 17253-17262 10 p.

Research output: Contribution to journalArticle

58 Scopus citations
2009

Biochemical characterization of the prolyl 3-hydroxylase 1·Cartilage-associated protein·cyclophilin B complex

Ishikawa, Y., Wirz, J., Vranka, J. A., Nagata, K. & Bächinger, H. P., Jun 26 2009, In : Journal of Biological Chemistry. 284, 26, p. 17641-17647 7 p.

Research output: Contribution to journalArticle

84 Scopus citations

Expression of prolyl 3-hydroxylase genes in embryonic and adult mouse tissues

Vranka, J., Scott Stadler, H. & Bächinger, H. P., Nov 9 2009, In : Cell Structure and Function. 34, 2, p. 97-104 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
2008

The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens

Ishikawa, Y., Vranka, J., Wirz, J., Nagata, K. & Bächinger, H. P., Nov 14 2008, In : Journal of Biological Chemistry. 283, 46, p. 31584-31590 7 p.

Research output: Contribution to journalArticle

79 Scopus citations
2006

CRTAP Is Required for Prolyl 3- Hydroxylation and Mutations Cause Recessive Osteogenesis Imperfecta

Morello, R., Bertin, T. K., Chen, Y., Hicks, J., Tonachini, L., Monticone, M., Castagnola, P., Rauch, F., Glorieux, F. H., Vranka, J., Bächinger, H. P., Pace, J. M., Schwarze, U., Byers, P. H., Weis, M. A., Fernandes, R. J., Eyre, D. R., Yao, Z., Boyce, B. F. & Lee, B., Oct 20 2006, In : Cell. 127, 2, p. 291-304 14 p.

Research output: Contribution to journalArticle

351 Scopus citations
2004

Prolyl 3-hydroxylase 1, enzyme characterization and identification of a novel family of enzymes

Vranka, J. A., Sakai, L. Y. & Bächinger, H. P., May 28 2004, In : Journal of Biological Chemistry. 279, 22, p. 23615-23621 7 p.

Research output: Contribution to journalArticle

136 Scopus citations
2001

Selective intracellular retention of extracellular matrix proteins and chaperones associated with pseudoachondroplasia

Vranka, J., Mokashi, A., Keene, D. R., Tufa, S., Corson, G., Sussman, M., Horton, W. A., Maddox, K., Sakai, L. & Bächinger, H. P., Nov 10 2001, In : Matrix Biology. 20, 7, p. 439-450 12 p.

Research output: Contribution to journalArticle

70 Scopus citations
1998

Effect of matrix metalloproteinases activity on outflow in perfused human organ culture

Bradley, J. M. B., Vranka, J., Colvis, C. M., Conger, D. M., Alexander, J. P., Fisk, A. S., Samples, J. R. & Acott, T. S., Dec 1998, In : Investigative Ophthalmology and Visual Science. 39, 13, p. 2649-2658 10 p.

Research output: Contribution to journalArticle

270 Scopus citations
1997

Discrete expression and distribution pattern of TIMP-3 in the human retina and choroid

Vranka, J. A., Johnson, E., Zhu, X., Shepardson, A., Alexander, J. P., Bradley, J. M. B., Wirtz, M. K., Weleber, R. G., Klein, M. L. & Acott, T. S., Mar 17 1997, In : Current Eye Research. 16, 2, p. 102-110 9 p.

Research output: Contribution to journalArticle

57 Scopus citations
1996

Gelatinase a and b inhibition kinetics using inhibitors which cause glaucoma in a model system

Vranka, J. A. & Acott, T. S., Dec 1 1996, In : FASEB Journal. 10, 6, p. A1405

Research output: Contribution to journalArticle

1 Scopus citations

TIMP3 expression in the human retina and choroid

Vranka, J. A., Shepardson, A., Johnson, E. C., Zhu, X. H., Alexander, J. P., Bradley, J. M. B., Wirtz, M. K., Weleber, R. G., Klein, M. L. & Acott, T. S., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3, p. S273

Research output: Contribution to journalArticle

4 Scopus citations