James (Jim) Rosenbaum

Professor

  • 17990 Citations
  • 67 h-Index
1974 …2021
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Research Output 1974 2020

2007
63 Citations (Scopus)

NOD2 Transgenic Mice Exhibit Enhanced MDP-Mediated Down-Regulation of TLR2 Responses and Resistance to Colitis Induction

Yang, Z., Fuss, I. J., Watanabe, T., Asano, N., Davey, M., Rosenbaum, J. J., Strober, W. & Kitani, A., Nov 2007, In : Gastroenterology. 133, 5, p. 1510-1521 12 p.

Research output: Contribution to journalArticle

Colitis
Peptidoglycan
Transgenic Mice
Trinitrobenzenes
Down-Regulation
6 Citations (Scopus)

Phenotypes, distribution, and morphological features of antigen-presenting cells in the murine cornea following intravitreal injection

Meng, Q., Yang, P., Jin, H., Rosenbaum, J. J., Li, B., Zhang, H., Zhou, H., Huang, X. & Planck, S., 2007, In : Molecular Vision. 13, p. 475-486 12 p.

Research output: Contribution to journalArticle

Intravitreal Injections
Antigen-Presenting Cells
Cornea
Phenotype
Ovalbumin
1 Citation (Scopus)

Possible association between scleritis and lymphoma.

Smith, L. K., Suhler, E., Lim, L. L., Choi, D., Cioffi, G. A. & Rosenbaum, J. J., Dec 2007, In : British Journal of Ophthalmology. 91, 12, p. 1728-1729 2 p.

Research output: Contribution to journalArticle

Factual Databases
Scleritis
Remission Induction
Hodgkin Disease
Lymphoma
1 Citation (Scopus)

Possible association between scleritis and lymphoma [18]

Smith, L. K., Suhler, E., Lim, L. L., Choi, D., Cioffi, G. A. & Rosenbaum, J. J., Dec 2007, In : British Journal of Ophthalmology. 91, 12, p. 1727-1729 3 p.

Research output: Contribution to journalArticle

Scleritis
Lymphoma
1 Citation (Scopus)

Primary Sclerosing Cholangitis and Uveitis: A Case Series

Hoang, L. T., Lim, L. L., Walton, R. C., Goldstein, D. A., Chalmers, B. & Rosenbaum, J. J., Mar 2007, In : American Journal of Ophthalmology. 143, 3, p. 534-536 3 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Uveitis
Inflammation
Health
40 Citations (Scopus)

Proteomic profiling of human retinal and choroidal endothelial cells reveals molecular heterogeneity related to tissue of origin

Zamora, D. O., Riviere, M., Choi, D., Pan, Y., Planck, S., Rosenbaum, J. J., David, L. & Smith, J. R., Oct 30 2007, In : Molecular Vision. 13, p. 2058-2065 8 p.

Research output: Contribution to journalArticle

Proteomics
Endothelial Cells
Proteins
Two-Dimensional Difference Gel Electrophoresis
Ubiquitin Thiolesterase
51 Citations (Scopus)

Therapy Insight: Scleritis and its relationship to systemic autoimmune disease

Smith, J. R., Mackensen, F. & Rosenbaum, J. J., Apr 2007, In : Nature Clinical Practice Rheumatology. 3, 4, p. 219-226 8 p.

Research output: Contribution to journalArticle

Scleritis
Autoimmune Diseases
Rheumatoid Arthritis
Inflammation
Therapeutics
9 Citations (Scopus)

Two Patients With the von Szily Reaction: Herpetic Keratitis and Contralateral Retinal Necrosis

Smith, L. K., Kurz, P. A., Wilson, D., Flaxel, C. & Rosenbaum, J. J., Mar 2007, In : American Journal of Ophthalmology. 143, 3, p. 536-538 3 p.

Research output: Contribution to journalArticle

Acute Retinal Necrosis Syndrome
Herpetic Keratitis
Retinitis
Necrosis
Human Herpesvirus 2
37 Citations (Scopus)

Unique gene expression profiles of donor-matched human retinal and choroidal vascular endothelial cells

Smith, J. R., Choi, D., Chipps, T. J., Pan, Y., Zamora, D. O., Davies, M. H., Babra, B., Powers, M. M., Planck, S. & Rosenbaum, J. J., Jun 2007, In : Investigative Ophthalmology and Visual Science. 48, 6, p. 2676-2684 9 p.

Research output: Contribution to journalArticle

Retinal Vessels
Transcriptome
Endothelial Cells
Posterior Uveitis
Gene Expression
2006
50 Citations (Scopus)

Alterations in peripheral blood lymphocyte cytokine expression in obesity

O'Rourke, R. W., Kay, T., Lyle, E. A., Traxler, S. A., Deveney, C., Jobe, B. A., Roberts, C., Marks, D. & Rosenbaum, J. J., Oct 2006, In : Clinical and Experimental Immunology. 146, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle

Obesity
Lymphocytes
Cytokines
Blood Cells
Interleukins
17 Citations (Scopus)

Antigen-specific accumulation of naïve, memory and effector CD4 T cells during anterior uveitis monitored by intravital microscopy

Dullforce, P. A., Seitz, G. W., Garman, K. L., Michael, J. A., Crespo, S. M., Fleischman, R. J., Planck, S., Parker, D. & Rosenbaum, J. J., Jan 2006, In : Cellular Immunology. 239, 1, p. 49-60 12 p.

Research output: Contribution to journalArticle

Anterior Uveitis
T-Lymphocytes
Antigens
Uveitis
Ovalbumin
10 Citations (Scopus)

Borrelia Hermsii Causing Relapsing Fever and Uveitis

Lim, L. L. & Rosenbaum, J. J., Aug 2006, In : American Journal of Ophthalmology. 142, 2, p. 348-349 2 p.

Research output: Contribution to journalArticle

Relapsing Fever
Borrelia
Uveitis
Camping
Intermediate Uveitis
45 Citations (Scopus)

Human endothelial cells express NOD2/CARD15 and increase IL-6 secretion in response to muramyl dipeptide

Davey, M., Martin, T., Planck, S., Lee, J., Zamora, D. & Rosenbaum, J. J., Mar 2006, In : Microvascular Research. 71, 2, p. 103-107 5 p.

Research output: Contribution to journalArticle

Acetylmuramyl-Alanyl-Isoglutamine
Endothelial cells
Interleukin-6
Endothelial Cells
Choroid
19 Citations (Scopus)

Human leukocytes express ephrinB2 which activates microvascular endothelial cells

Zamora, D. O., Babra, B., Pan, Y., Planck, S. & Rosenbaum, J. J., Aug 2006, In : Cellular Immunology. 242, 2, p. 99-109 11 p.

Research output: Contribution to journalArticle

Leukocytes
Endothelial Cells
Iris
Ephrins
Lymphocytes

Inflammatory Eye Disease in Spondyloarthritis

Wertheim, M. S., Martin, T. & Rosenbaum, J. J., 2006, Ankylosing Spondylitis and the Spondyloarthropathies. Elsevier Inc., p. 107-116 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Eye Diseases

In reply [2]

Suhler, E. B., Smith, J. R., Wertheim, M. S., Lauer, A. K., Kurz, D. E., Pickard, T. D. & Rosenbaum, J. T., 2006, In : Archives of Ophthalmology. 124, 10, p. 1505-1506 2 p.

Research output: Contribution to journalArticle

In reply [2]

Suhler, E. B., Smith, J. R., Wertheim, M. S., Lauer, A. K., Kurz, D. E., Pickard, T. D. & Rosenbaum, J. T., Aug 2006, In : Archives of Ophthalmology. 124, 8, p. 1211-1212 2 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Intravital microscopy of leukocyte-endothelial dynamics using the Heidelberg confocal laser microscope in scleritis and allergic conjunctivitis

Lim, L. L., Hoang, L., Wong, T., Planck, S., Ronick, M. B., Gould, R. R., Mathers, W. & Rosenbaum, J. J., Oct 26 2006, In : Molecular Vision. 12, p. 1302-1305 4 p.

Research output: Contribution to journalArticle

Scleritis
Allergic Conjunctivitis
Lasers
Leukocytes
Eye Diseases
3 Citations (Scopus)

Modification of the Woodruff-Stamper assay demonstrates binding of Toxoplasma gondii tachyzoites to retinal vascular endothelium

Chipps, T. J., Streeter, P., Franc, D. T., Neumeyer, K., Planck, S., Rosenbaum, J. J. & Smith, J. R., May 30 2006, In : Journal of Immunological Methods. 312, 1-2, p. 209-213 5 p.

Research output: Contribution to journalArticle

Retinal Vessels
Toxoplasma
Vascular Endothelium
Retina
Endothelium
4 Citations (Scopus)

Non-invasive detection of multinucleated giant cells in the conjunctiva of patients with sarcoidosis by in-vivo confocal microscopy

Wertheim, M. S., Mathers, W., Lim, L., Watkins, A. S., Mackensen, F., O'Malley, J. P. & Rosenbaum, J. J., Jul 1 2006, In : Ocular Immunology and Inflammation. 14, 4, p. 203-206 4 p.

Research output: Contribution to journalArticle

Conjunctiva
Giant Cells
Sarcoidosis
Confocal Microscopy
Inflammation
136 Citations (Scopus)

Pediatric granulomatous arthritis: An international registry

Rosé, C. D., Wouters, C. H., Meiorin, S., Doyle, T. M., Davey, M., Rosenbaum, J. J. & Martin, T., Oct 2006, In : Arthritis and Rheumatism. 54, 10, p. 3337-3344 8 p.

Research output: Contribution to journalArticle

Pedigree
Registries
Arthritis
Mutation
Eye Diseases
52 Citations (Scopus)

Primary Treatment of Acute Retinal Necrosis with Oral Antiviral Therapy

Emerson, G. G., Smith, J. R., Wilson, D., Rosenbaum, J. J. & Flaxel, C., Dec 2006, In : Ophthalmology. 113, 12, p. 2259-2261 3 p.

Research output: Contribution to journalArticle

Acute Retinal Necrosis Syndrome
Antiviral Agents
valacyclovir
Acyclovir
Retinal Detachment

Registration of microscopic iris image sequences using probabilistic mesh

Song, X., Myronenko, A., Plank, S. R. & Rosenbaum, J. J., 2006, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Springer Verlag, Vol. 4191 LNCS - II. p. 553-560 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 4191 LNCS - II).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Iris
Image Sequence
Registration
Mesh
Immune system
10 Citations (Scopus)

Registration of microscopic iris image sequences using probabilistic mesh.

Song, X., Myronenko, A., Plank, S. R. & Rosenbaum, J. J., 2006, Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Pt 2 ed. Vol. 9. p. 553-560 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Iris
Artifacts
Immune System
Leukocytes
24 Citations (Scopus)

Retention time for corticosteroid-sparing systemic immunosuppressive agents in patients with inflammatory eye disease

Baker, K. B., Spurrier, N. J., Watkins, A. S., Smith, J. R. & Rosenbaum, J. J., Dec 2006, In : British Journal of Ophthalmology. 90, 12, p. 1481-1485 5 p.

Research output: Contribution to journalArticle

Eye Diseases
Immunosuppressive Agents
Adrenal Cortex Hormones
Mycophenolic Acid
Pharmaceutical Preparations
1 Citation (Scopus)

Wegener's Granulomatosis: More than Meets the Eye

Rosenbaum, J. J., Apr 2006, In : Seminars in Arthritis and Rheumatism. 35, 5, p. 271 1 p.

Research output: Contribution to journalArticle

Granulomatosis with Polyangiitis
Eye Diseases
Differential Diagnosis
2005
51 Citations (Scopus)

A locus on chromosome 9p predisposes to a specific disease manifestation, acute anterior uveitis, in ankylosing spondylitis, a genetically complex, multisystem, inflammatory disease

Martin, T., Zhang, G., Luo, J., Jin, L., Doyle, T. M., Rajska, B. M., Coffman, J. E., Smith, J. R., Becker, M. D., Mackensen, F., Khan, M. A., Levinson, R. D., Schumacher, H. R., Wade, N. K., Rosenbaum, J. J. & Reveille, J. D., Jan 2005, In : Arthritis and Rheumatism. 52, 1, p. 269-274 6 p.

Research output: Contribution to journalArticle

Anterior Uveitis
Ankylosing Spondylitis
Acute Disease
Chromosomes
HLA-B Antigens
239 Citations (Scopus)

A prospective trial of infliximab therapy for refractory uveitis: Preliminary safety and efficacy outcomes

Suhler, E., Smith, J. R., Wertheim, M. S., Lauer, A. A., Kurz, D. E., Pickard, T. D. & Rosenbaum, J. J., Jul 2005, In : Archives of Ophthalmology. 123, 7, p. 903-912 10 p.

Research output: Contribution to journalArticle

Uveitis
Safety
Therapeutics
Inflammation
Patient Outcome Assessment
9 Citations (Scopus)
Uveitis
Homologous Transplantation
Graft vs Host Disease
Bone Marrow Transplantation
Cyclosporine
111 Citations (Scopus)

Blau syndrome mutation of CARD15/NOD2 in sporadic early onset granulomatous arthritis

Rosé, C. D., Doyle, T. M., McIlvain-Simpson, G., Coffman, J. E., Rosenbaum, J. J., Davey, M. & Martin, T., Feb 2005, In : Journal of Rheumatology. 32, 2, p. 373-375 3 p.

Research output: Contribution to journalArticle

Arthritis
Mutation
Cheek
DNA
Amino Acid Substitution
11 Citations (Scopus)

Differential E-selectin expression by iris versus retina microvascular endothelial cells cultured from the same individuals

Silverman, M. D., Babra, B., Pan, Y., Planck, S. & Rosenbaum, J. J., Jul 2005, In : Microvascular Research. 70, 1-2, p. 32-42 11 p.

Research output: Contribution to journalArticle

E-Selectin
Endothelial cells
Iris
Retina
Endothelial Cells
21 Citations (Scopus)

Genetics in uveitis

Martin, T. & Rosenbaum, J. J., Mar 2005, In : International Ophthalmology Clinics. 45, 2, p. 15-30 16 p.

Research output: Contribution to journalArticle

Nod2 Signaling Adaptor Protein
Intracellular Signaling Peptides and Proteins
Uveitis
Major Histocompatibility Complex
Cytokines
11 Citations (Scopus)
Conjunctival Diseases
Giant Cells
Sarcoidosis
Confocal Microscopy
Biopsy
13 Citations (Scopus)

Lack of association of matrix metalloproteinase 3 (MMP3) genotypes with ankylosing spondylitis susceptibility and severity

Jin, L., Weisman, M., Zhang, G., Ward, M., Luo, J., Bruckel, J., Inman, R., Khan, M. A., Schumacher, H. R., Maksymowych, W. P., Mahowald, M., Martin, T., Rosenbaum, J. J., Yu, D. T. Y., Stone, M., Watson, J., Dickman, E., Davis, J. & Reveille, J. D., Jan 2005, In : Rheumatology. 44, 1, p. 55-60 6 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 3
Ankylosing Spondylitis
Genotype
Single Nucleotide Polymorphism
Pedigree
35 Citations (Scopus)

Long-term follow-up of patients with birdshot retinochoroidopathy treated with systemic immunosuppression

Becker, M. D., Wertheim, M. S., Smith, J. R. & Rosenbaum, J. J., Aug 2005, In : Ocular Immunology and Inflammation. 13, 4, p. 289-293 5 p.

Research output: Contribution to journalArticle

Immunosuppression
Uveitis
Adrenal Cortex Hormones
Azathioprine
Cyclosporine
18 Citations (Scopus)

Retisert Bausch & Lomb/control delivery systems

Lim, L. L., Smith, J. R. & Rosenbaum, J. J., Nov 2005, In : Current Opinion in Investigational Drugs. 6, 11, p. 1159-1167 9 p.

Research output: Contribution to journalArticle

Fluocinolone Acetonide
Posterior Eye Segment
Uveitis
41 Citations (Scopus)
Retinal Neovascularization
Hyperoxia
Ephrins
Pathologic Neovascularization
Oxygen
1918 Citations (Scopus)

Standardization of uveitis nomenclature for reporting clinical data. Results of the first international workshop

THE STANDARDIZATION OF UVEITIS NOMENCLATURE (SUN) WORKING GROUP, Sep 1 2005, In : American Journal of Ophthalmology. 140, 3, p. 509-516 8 p.

Research output: Contribution to journalArticle

Uveitis
Terminology
Research Design
Education
Inflammation
15 Citations (Scopus)

The role of choroidal and retinal biopsies in the diagnosis and management of atypical presentations of uveitis

Lim, L. L., Suhler, E. B., Rosenbaum, J. T., Wilson, D. J., Albert, D. M., Thompson, J. T., Elner, S. G., Cox, M. S., Mieler, W. F., Eagle, R. C. & Wilson, D. J., 2005, In : Transactions of the American Ophthalmological Society. 103, p. 84-92 9 p.

Research output: Contribution to journalArticle

Uveitis
Biopsy
Vitrectomy
Pathology
Temazepam
29 Citations (Scopus)

Toxoplasmosis retinochoroiditis and elevated intraocular pressure: A retrospective study

Westfall, A. C., Lauer, A. A., Suhler, E. & Rosenbaum, J. J., Feb 2005, In : Journal of Glaucoma. 14, 1, p. 3-10 8 p.

Research output: Contribution to journalArticle

Toxoplasmosis
Intraocular Pressure
Retrospective Studies
Anterior Uveitis
Anterior Chamber
5 Citations (Scopus)

Treatment of corticosteroid dependent optic neuropathy with intravenous immunoglobulin

Kurz, D., Egan, R. A. & Rosenbaum, J. J., Dec 2005, In : American Journal of Ophthalmology. 140, 6, p. 1132-1133 2 p.

Research output: Contribution to journalArticle

Optic Nerve Diseases
Intravenous Immunoglobulins
Adrenal Cortex Hormones
Mycophenolic Acid
Retinal Hemorrhage
4 Citations (Scopus)

Uveitis seroreactivity to candidate pANCA antigens: Mycobacterial HupB and histone H1(69-171)

Kassan, H., Cohavy, O., Rosenbaum, J. J., Braun, J. & Gordon, L. K., Apr 2005, In : Ocular Immunology and Inflammation. 13, 2-3, p. 191-198 8 p.

Research output: Contribution to journalArticle

Uveitis
Histones
Antigens
Antineutrophil Cytoplasmic Antibodies
Antibodies
28 Citations (Scopus)

β3-Adrenergic receptors mediate choroidal endothelial cell invasion, proliferation, and cell elongation

Steinle, J. J., Zamora, D. O., Rosenbaum, J. J. & Granger, H. J., Jan 2005, In : Experimental Eye Research. 80, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

Adrenergic Receptors
Endothelial Cells
Cell Proliferation
Cyclic GMP-Dependent Protein Kinases
Adrenergic Agonists
2004
36 Citations (Scopus)

APCs in the anterior uveal tract do not migrate to draining lymph nodes

Dullforce, P. A., Garman, K. L., Seitz, G. W., Fleischmann, R. J., Crespo, S. M., Planck, S., Parker, D. & Rosenbaum, J. J., Jun 1 2004, In : Journal of Immunology. 172, 11, p. 6701-6708 8 p.

Research output: Contribution to journalArticle

Lymph Nodes
Anterior Chamber
Video Microscopy
Lymphatic Vessels
Conjunctiva
28 Citations (Scopus)
Antirheumatic Agents
Behcet Syndrome
Uveitis
Tumor Necrosis Factor-alpha
Monoclonal Antibodies
22 Citations (Scopus)

Effect of etanercept on iritis in patients with ankylosing spondylitis [5]

Rosenbaum, J. J., Nov 2004, In : Arthritis and Rheumatism. 50, 11, p. 3736-3737 2 p.

Research output: Contribution to journalArticle

Iritis
Antirheumatic Agents
Tumor Necrosis Factor Receptors
Ankylosing Spondylitis
Immunoglobulin G
101 Citations (Scopus)

Genetic studies in familial ankylosing spondylitis susceptibility

Zhang, G., Luo, J., Bruckel, J., Weisman, M. A., Schumacher, H. R., Khan, M. A., Inman, R. D., Mahowald, M., Maksymowych, W. P., Martin, T., Yu, D. T. Y., Stone, M., Rosenbaum, J. J., Newman, P., Lee, J., McClain, J. A., West, O. C., Jin, L. & Reveille, J. D., Jul 2004, In : Arthritis and Rheumatism. 50, 7, p. 2246-2254 9 p.

Research output: Contribution to journalArticle

Ankylosing Spondylitis
Major Histocompatibility Complex
Alleles
Chromosomes
HLA-DRB1 Chains
5 Citations (Scopus)

How do you know?

Rosenbaum, J. J., Deodhar, A. A., Suhler, E. & Smith, J. R., Aug 2004, In : British Journal of Ophthalmology. 88, 8, p. 980-981 2 p.

Research output: Contribution to journalArticle

Biological Therapy
Uveitis
Visual Acuity
Randomized Controlled Trials

Immunologists ponder glaucoma: A few inflammatory remarks

Rosenbaum, J. J. & Smith, J. R., Dec 2004, In : Journal of Glaucoma. 13, 6, p. 439-440 2 p.

Research output: Contribution to journalArticle

Uveitis
Glaucoma
9 Citations (Scopus)

In vivo confocal microscopy: Increased conjunctival or episcleral leukocyte adhesion in patients who wear contact lenses with lower oxygen permeability (Dk) values

Nguyen, T. H., Dudek, L. T., Krisciunas, T. C., Matiaco, P., Planck, S., Mathers, W. & Rosenbaum, J. J., Oct 2004, In : Cornea. 23, 7, p. 695-700 6 p.

Research output: Contribution to journalArticle

Contact Lenses
Confocal Microscopy
Permeability
Leukocytes
Oxygen